RABIGEM D 30/20MG TABLET 10'S

Introduction About RABIGEM D 30/20MG TABLET

RABIGEM D 30/20MG TABLET is used to manage Gastro-Esophageal Reflux Disease
(GERD) among patients who have not responded adequately to rabeprazole alone. It
is a combination of Domperidone and Rabeprazole which belongs to the group of
medicines called Dopamine Antagonists and Proton pump inhibitors respectively.
It can also be used to manage pe
NSAIDs use.

Along management with RABIGEM D 30/20MG TABLET, try to eat less spicy foods and
drink plenty of water. Avoid smoking or alcohol consum
your existing condition. Patients receiving long-term management with the
medicine should be kept on regular surveillance to rule out the risk of
hypomagnesaemia (decreased magnesium levels in blood) and bone fracture,
predominantly in the elderly patients and in patients with other recognized risk
factors.

Before taking RABIGEM D 30/20MG TABLET inform your doctor if you have any liver,
kidney or heart problems. Your doctor may reduce the dose or suggest an
alternative therapy. It is not recommended for use in pregnant or breastfeeding
women and in children (aged less than 18 years). It should be used with caution
in elderly patients (above 65 years of age). The most common side effects are
nausea, vomiting, stomach pain, diarrhea or constipation. Consult your doctor if
any of these above side effects worsen.

Uses Of RABIGEM D 30/20MG TABLET

It is used to manage:

• pe
• Gastro-Esophageal Reflux Disease (GERD)

How RABIGEM D 30/20MG TABLET Works

RABIGEM D 30/20MG TABLET reduces stomach ulcers and acid reflux, where
Rabeprazole acts by inhibiting the secretions of stomach acid and Domperidone
acts by increasing bowel movements and facilitating gastric emptying, thus
leading to rapid symptom relief and healing of stomach ulcers and esophageal
lesions.

How to use RABIGEM D 30/20MG TABLET

• Take RABIGEM D 30/20MG TABLET as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition

Side Effects Of RABIGEM D 30/20MG TABLET

Common side effects of RABIGEM D 30/20MG TABLET:

• nausea, vomiting
• diarrhea, constipation, stomach pain, flatulence
• cough, sore throat, runny nose
• back pain
• headache, dizziness
• dry mouth
• benign polyps in the stomach
• indigestion, belching in the stomach (excess air accumulation in the stomach)
• urinary tract infection

Stop taking RABIGEM D 30/20MG TABLET and contact your doctor immediately if you
experience the following side effects:

• severe allergic reaction (sudden wheezing, swelling of lips, face or body, rash, fainting or difficulties swallowing)
• symptoms of liver problems (yellow skin, dark urine and tiredness)
• severe skin reactions such as erythema multiforme, stevens-johnson syndrome or toxic epidermal necrolysis (reddening of skin with blisters or peeling and may be associated with a high fever and joint pains, also severe blisters and bleeding in the lips, eyes, mouth, nose and genitals)
• seizures
• involuntary movements of the face or arms and legs, excessive trembling, excessive muscle stiffness or muscle spasm
• heart rhythm disorders (rapid or irregular heartbeat)

Warning & Precautions

!### Pregnancy

ContraindicatedRABIGEM D 30/20MG TABLET is not recommended for use in pregnant women.

!### Breastfeeding

ContraindicatedRABIGEM D 30/20MG TABLET is not recommended for use in breast-feeding women.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you experience sleepiness, confusion or
less control over your movements.

!### Alcohol

Consult your doctorAvoid consum
aggravate your existing condition.

!### Kidney

ContraindicatedRABIGEM D 30/20MG TABLET is not recommended for use in patients with kidney
impairment.

!### Liver

Consult your doctorRABIGEM D 30/20MG TABLET is not recommended for use in patients with moderate or
severe liver impairment and it should be used with caution in patients with
liver problems.

!### Allergy

ContraindicatedDo not take RABIGEM D 30/20MG TABLET if you are allergic to Domperidone or
Rabeprazole or any other ingredients of this medicine.

!### Heart Disease

ContraindicatedRABIGEM D 30/20MG TABLET is not recommended for use in patients with heart
problems such as prolongation of QT interval or congestive heart failure.

!### Use In Pediatrics

ContraindicatedRABIGEM D 30/20MG TABLET is not recommended for use in children and adolescents
(aged less than 18 years) due to lack of safety and effectiveness.

!### Use In Geriatrics

Use with CautionRABIGEM D 30/20MG TABLET should be taken with caution in elderly patients (aged
65 years or above).

Others

RABIGEM D 30/20MG TABLET is not recommended for use if you:

• Have bloody stools or bleeding in the gut
• Have blockage or tear in the intestines
• Have severe fluid or electrolyte disturbances
• Have prolactinoma
• Have phenylketonuria
• Have problem that causes low levels of potassium or magnesium or high levels of potassium in the blood
• Have hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsor

Before taking RABIGEM D 30/20MG TABLET, inform your physician if you:

• Have osteoporosis
• Have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
• Are going to test Chromogr

Interactions

A. Drug-Drug interactions:

Before taking the medicine, inform to your doctor if you are taking any of these
medicines:

• Prokinetic agent (Ex. Cisapride, dolasetron, prucalopride, diphem
• Cardiac glycosides (Ex. Digoxin, apomorphine, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, diltiazem or verapamil)
• Ant-viral agents (Ex. Atazanavir, nelfinavir, saquinavir, Telaprevir)
• Antipsychotics (Ex. Haloperidol, pimozide, sertindole)
• Antidepressants (Ex. Escitalopram or citalopram)
• Antibiotics (Ex. Moxifloxacin, erythromycin, levofloxacin, clarithromycin, telithromycin or amoxicillin)
• Antimalarials (Ex. Halofantrine, lumefantrine)
• Antihistamines (Ex. Mizolastine, mequitazine)
• Nonsteroidal antiestrogens (Ex. Toremifene, vandet
• Antimetabolites (Ex. Methotrexate)
• Antihypertensives (Ex. Bepridil)
• Opioid narcotics (Ex. Methadone)
• Iron salts
• Immunosuppressants (Ex. Tacrolimus or mycophenolate mofetil)
• Antifungals (Ex. Ketoconazole, itraconazole)
• Anti-infective (Ex. Pentamidine)
• Anticoagulants (Ex. Warfarin)

Overdosage:

If you or anyone else take too much of RABIGEM D 30/20MG TABLET, contact your
doctor immediately or go to a hospital straight away. Overdosage symptoms are
altered consciousness, agitation, convulsions, disorientation, sleepiness and
extrapyramidal reactions (such as rigidity, tremor, drooling).

Synopsis

Drug	:	Domperidone, Rabeprazole
Pharmacological Category	:	Dopamine antagonist, Proton pump inhibitor
Therapeutic Indication	:	Pe
Dosage Forms	:	Tablet, Capsule

More Information

FAQs About RABIGEM D 30/20MG TABLET

Q: Can RABIGEM D 30/20MG TABLET cause diarrhea?

A: Yes. RABIGEM D 30/20MG TABLET may cause diarrhea in some individuals. Keep
yourself hydrated by drinking plenty of fluids, oral electrolytes and juices. Do
not self-manage diarrhea if it persists for a longer period. Contact your doctor
for advice.

Q: Can RABIGEM D 30/20MG TABLET cause acid reflux?

A: No. RABIGEM D 30/20MG TABLET is used to manage Gastro-Esophageal Reflux
Disease (GERD) and does not cause acid reflux. If you experience any unusual
symptoms after taking the medicine, consult your doctor for advice.

Q: Can RABIGEM D 30/20MG TABLET cause kidney damage?

A: RABIGEM D 30/20MG TABLET may rarely cause damage to your kidneys (Ex.
interstitial nephritis). However, inform your doctor immediately if you
experience any signs of kidney damage such as dark urine, blood in urine,
painful urination or lower abdominal discomfort during management with this
medicine.

Q: When and how should I take RABIGEM D 30/20MG TABLET?

A: Take RABIGEM D 30/20MG TABLET on an empty stomach or as advised by your
physician. Swallow the medicine as a whole and do not crush or chew the
medicine.

Q: Can RABIGEM D 30/20MG TABLET be used in children?

A: No. RABIGEM D 30/20MG TABLET is not recommended for use in children and
adolescents (below 18 years) due to lack of safety and effectiveness. Consult
your child’s doctor if your child experiences any symptoms of gastro-esophageal
reflux disease or pe
stomach, stomach pain, heartburn, burping, etc).

Useful Diagnostic Tests

• Complete Blood Count (CBC)
• Stool Complete Analysis