Paniv 20mg Injection 1'S

Introduction About P

P
medicines called Proton pump inhibitors. It is used to manage pe
gastroesophageal reflux disease (GERD) or reflux esophagitis and its associated
symptoms such as acidity, heartburn, acid reflux and pain in swallowing.

Pe
esophagus or intestines. It causes severe stomach pain with sensation of
flatulence, indigestion, vomiting and fatigue.

GERD is a chronic digestive disease in which the acid from the stomach
frequently flows into the esophagus leading to irritation of lining of food
pipe. Symptoms include heartburn, chest pain, nausea, sensation of lump in
throat and stomach discomfort.

Reflux esophagitis can be defined as the inflammation of the food pipe
accomp
Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete
more acid) and other acid related diseases of the gut.

During management with P
your kidney functions, liver functions and blood magnesium levels to avoid the
risk of unwanted side effects.

Before receiving P
kidney or heart problems. You must also inform your doctor if you have weak
bones or any previous history of bleeding in the gut.

Consult your doctor before receiving P
breastfeeding. The most common side effects of receiving P
pain and inflammation at the site of injection. Consult your doctor if this side
effect bothers you.

You must also inform your doctor immediately if you experience severe tiredness
with abnormal muscle movements, dizziness, confusion, disorientation and
irregular heartbeat after receiving P
of low magnesium levels in blood.

Uses Of P

It is used to manage:

• Pe
• Gastrointestinal Reflux disease (GERD)
• Reflux esophagitis (inflammation of the esophagus)
• Acidity, Heartburn, Pain in swallowing
• Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete more acid)

How P

P
secretion by the blocking the actions of a protein membrane called H+K+Atpase
(proton pump) across the stomach lining. As a result, it manages the worsening
of ulcers, heals the existing ulcers and esophageal lesions and provides relief
from the unpleasant symptoms of GI tract (such as acidity, heartburn and acid
reflux).

How to use P

P
into the vein (intravenously). Your doctor will decide the correct dose and
duration of therapy for you depending upon your age, body weight and disease
condition.

Side Effects Of P

Common

• Benign polyps in the stomach
• Injection site reactions (pain and inflammation)

Uncommon

• Headache, dizziness, drowsiness
• Anxiety, sleeplessness
• Breast enlargement in both men and in women
• Feeling weak
• Fragile bones (risk of bone fracture)
• Nausea or vomiting
• Diarrhea, constipation, stomach pain, flatulence
• Dry mouth

Rare

• Blurred vision
• Joint pain, muscle pain
• Raised body temperature
• Swelling of the extremities (peripheral oedema)
• Depression
• Breast enlargement in males
• Low WBC count in blood
• Taste disorders

Contact your doctor immediately if you experience any of the following side
effects after receiving P

• Severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
• Signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
• Severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
• Signs of kidney problem (such as lower back pain, painful urination)
• Signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
• Skin rashes on sun exposed areas
• Sudden weight loss, looking pale and weak (anemia)
• Signs of bleeding in the gut (such as bloody vomits/stools)
• Chest pain
• Severe, persistent diarrhea
• Fast or irregular heartbeat, difficulty in breathing, feeling faint
• Fits
• Uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture

How To Manage Side Effects

!### Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Do not consume excessive
alcohol, as it could aggravate your dizziness. Consult your doctor if your
dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

!### Injection Site Reactions

Place an ice pack on the affected area. Do not move the injection site often.
Consult your doctor if the symptom did not improve.

!### Nausea And Vomiting

Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if
nausea worsens.

Warning & Precautions

!### Pregnancy

Consult your doctorP
necessary by the physician. Therefore, consult your doctor before receiving it.

!### Breastfeeding

Consult your doctorP
in breastfeeding women only if it is considered necessary by the physician.
Consult your doctor for advice.

!### Driving and Using Machines

SafeP
tools or machines. However, do not drive or handle heavy tools or machines if
your ability is affected by P

!### Alcohol

ContraindicatedAvoid consum
aggravate your existing condition.

!### Kidney

Use with CautionP
problems. Therefore, consult your doctor before receiving it.

!### Liver

Use with CautionP
problems. Therefore, consult your doctor before receiving it.

!### Allergy

ContraindicatedDo not receive P

!### Use In Pediatrics

ContraindicatedP
(aged below 18 years). However, consult your doctor before receiving it.

!### Use In Geriatrics

Use with CautionP
years and above). Therefore, consult your doctor before receiving it.

Others

Before receiving P

• Have osteoporosis
• Have a history of bleeding in the gut
• Have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
• Are going to test Chromogr

Interactions

A. Drug-Drug interactions:

Before receiving P
any of the following medicines such as:

• Medicines used to manage fungal infections (such as ketoconazole, itraconazole and Posaconazole)
• Erlotinib (a medicine used to manage cancer)
• Warfarin and phenprocoumon (medicines used for blood thinning)
• Methotrexate (a medicine used to manage cancer and autoimmune diseases)
• Atazanavir (a medicine used to manage HIV infection)
• Fluvoxamine (a medicine used to manage depression)
• Rifampicin (a medicine used to manage tuberculosis)
• St. John’s wort (an herbal medicine used to manage depression)

Overdosage:

P
a hospital, and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Pantoprazole
Pharmacological Category	:	Proton pump inhibitors
Therapeutic Indication	:	Pe
Dosage Forms	:	Tablet, Capsule, Injection, Infusion, Prefilled Syringe, Kit

More Information

Storage

• Keep P
• Store P

FAQs About P

Q: What is P

A: P
disease (GERD) and reflux esophagitis and its associated symptoms such as
acidity, heartburn, acid reflux and pain in swallowing. It can also be used to
manage Zollinger-Ellison syndrome.

Q: How and when to take P

A: P
to you only by a doctor or a nurse into the vein (intravenously).

Q: How long should I take P

A: You need to take P
by your doctor. Your doctor will decide the correct dose and duration of therapy
for you depending upon your age, body weight and disease condition.

Q: What are the most common side effects of receiving P

A: The most common side effects of receiving P
mouth, constipation and flatulence. Consult your doctor if any of these side
effect bothers you.

Q: What precautions do I need to follow while receiving P

A: Before receiving P
liver, kidney or heart problems. You must also inform your doctor if you have
weak bones or a previous history of bleeding in the gut. Consult your doctor
before receiving P
Regularly visit your doctor and take all the blood tests recommended by your
doctor without fail.

Q: Can I take medication for high blood pressure along with P

A: It is not advisable to take medicines to control blood pressure while
receiving P
interactions with P

Q: Can P

A: P
considered necessary by the physician. Therefore, consult your doctor before
receiving it.

Q: How much P

A: P
doctor will decide the correct dose and duration of therapy for you depending
upon your age, body condition and severity of the disease condition.

Q: Can P

A: Yes. Constipation is a common side effect of using P
plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as
drink plenty of water and exercise more regularly when receiving this medicine.
Contact your doctor if this side effect bothers you.

Q: Can P

A: Yes. Dry mouth is a common side effect of using P
your doctor if this side effect bothers you.