Rebozen DSR Capsule 10'S

Introduction About REBOZEN DSR CAPSULE

REBOZEN DSR CAPSULE is a dual-action formulation designed to support stomach
comfort and digestive balance. It contains Rabeprazole and Domperidone, two
clinically studied components that reduce excessive stomach acid and support
smoother digestion. This combination is widely recommended for individuals
experiencing symptoms linked to acidity, heartburn, or discomfort after meals.

Along management with REBOZEN DSR CAPSULE , try to eat less spicy foods and
drink plenty of water. Avoid smoking or alcohol consum
your existing condition. Patients receiving long-term management with the
medicine should be kept on regular surveillance to rule out the risk of
hypomagnesaemia (decreased magnesium levels in blood) and bone fracture,
predominantly in the elderly patients and in patients with other recognized risk
factors.

Some individuals may experience mild effects such as headache, dry mouth,
abdominal discomfort, constipation, dizziness, or nausea. These effects are
generally temporary. If they persist, contact your healthcare provider for
guidance.

Store REBOZEN DSR CAPSULE in a cool, dry place away from direct sunlight and
moisture. Keep out of reach of children and pets.

Key Composition

• Rabeprazole (20 mg): Helps control the acid produced in the stomach by selectively acting on proton pumps
• Domperidone (30 mg): Aids in faster stomach emptying and minimizes sensations of nausea or bloating

Uses Of REBOZEN DSR CAPSULE

• Used to support stomach comfort and digestive balance

Benefits of REBOZEN DSR CAPSULE

• Supports long-lasting relief from acid-related discomfort
• Improves digestive motility and helps manage fullness or heaviness after eating
• Promotes digestive comfort by neutralising excess gastric acid
• Enhances daily comfort for individuals with frequent acidity or reflux symptoms

How REBOZEN DSR CAPSULE Works

REBOZEN DSR CAPSULE works through a dual mech
acid secretion at its source, ensuring a well-balanced gastric environment.
Meanwhile, Domperidone restores the normal movement of the stomach and
intestines, managing acid backflow and improving food passage for a more
comfortable digestive experience.

Dual Mech

Rabeprazole belongs to the class of proton pump modulators that reduce acid
secretion at its source. Once absorbed in the intestine, it reaches the
acid-producing parietal cells in the stomach lining. Here, it selectively and
irreversibly binds to the H/K ATPase enzyme system, also known as the proton
pump, the final step in acid secretion. By blocking the hydrogen ion exchange
process, Rabeprazole manages excessive acid release into the stomach lumen,
thereby increasing gastric pH. It acts faster than many other molecules in its
class due to its ability to activate at higher pH levels, efficiently reducing
acid production even at minimal acidity. This long-acting acid suppression helps
relieve common signs of acidity and promotes a stable digestive environment.

2. Gut Movement through Domperidone:

Domperidone supports the mech
motility. It selectively blocks dopamine D2 receptors found in the upper
gastrointestinal tract, which normally act to slow stomach contractions. By
inhibiting these receptors, Domperidone increases the tone of the lower
esophageal sphincter (LES), facilitates faster gastric emptying, and decreases
the backward flow of food and acid into the esophagus. It also improves
intestinal motion, reducing sensations of bloating, heaviness, or delayed
digestion after meals, particularly useful for individuals who experience reflux
linked to slow gastric transit.

3. Integrated Digestive Action:

Together, these two mech
acid stability, while Domperidone o
combination supports digestive comfort by minimizing acid build-up while
promoting efficient passage of food through the stomach and intestines. It is
particularly suited for individuals who face recurring symptoms like heartburn,
acid reflux, or post-meal fullness due to poor gastric motility or high acid
output. This science-backed synergy makes REBOZEN DSR CAPSULE effective for
holistic digestive maintenance under medical supervision.

“Quick Fact Highlights” explaining why the dual combination is clinically valued

• Clinically synergistic formulation: The combination of Rabeprazole (20 mg) and Domperidone (30 mg SR) works through a dual mech
• Science-backed acid regulation:Rabeprazole acts at the final step of acid production by blocking the H/K ATPase enzyme, also known as the proton pump. This action significantly reduces acid secretion and maintains o
• Enhanced digestion support:Domperidone increases the movement of the stomach and upper intestinal tract, promoting quicker stomach emptying and minimizing post-meal bloating, nausea, and reflux symptoms
• Faster symptom control:Rabeprazole has one of the quickest onset times among proton pump inhibitors, beginning to act within 1 hour of ingestion, offering prompt relief in cases of severe acidity and heartburn
• Persistent gastric balance:The sustained-release form of Domperidone maintains smooth motility throughout the day, managing the recurrence of reflux episodes and late-night acidity, a key benefit for individuals with night-time acid reflux or delayed digestion
• Improved patient quality of life:This dual approach relieves not just acid discomfort but also digestive sluggishness, making it beneficial for individuals who experience post-meal heaviness, belching, or regurgitation along with acidity
• Clinically preferred for complex acid disorders:Physic
• Well-tolerated and safety-monitored:The formulation has a proven safety profile when used as prescribed, with side effects such as mild headache or dizziness typically resolving with continued use

How to use REBOZEN DSR CAPSULE

Take the capsule before meals, preferably in the morning, or as directed by your
healthcare provider. Swallow the capsule whole with water without crushing or
chewing. Regular use under professional guidance ensures o

1. How to Take REBOZEN DSR CAPSULE Safely

Swallow the capsule whole with water without biting, breaking, or crushing it.
The capsule should not be chewed as it is designed for delayed release. It is
best taken on an empty stomach for o
effect. Avoid taking it with caffeinated or acidic drinks.

2. Dosage and Duration

The dosage and duration depend on your medical condition, age, and response to
therapy. Most individuals experience benefits with once-daily use, but in some
cases, the doctor may recommend twice-daily administration. Continue the capsule
for the prescribed duration, even if symptoms improve early.

3. Dosage Guidelines for Adults and Elderly

• For most adult users, the typical dosage is one REBOZEN DSR CAPSULE (Rabeprazole 20 mg + Domperidone 30 mg) taken once daily, ideally 30 minutes before a meal, preferably in the morning. The capsule must be swallowed whole with water, without crushing or chewing, to ensure proper drug release and absor
• Elderly individuals often metabolize medicines more slowly and may have pre-existing heart, kidney, or liver impairments. Therefore, they should only take the prescribed dose once daily, under close medical supervision
• Long-term users may require periodic assessment of magnesium, calcium, and vitamin B12 levels, as prolonged use can mildly affect nutrient absor

What if I forgot to take REBOZEN DSR CAPSULE

If you forget to take a dose, take it as soon as you remember unless it is
almost time for the next one. Do not double the dose to make up for the missed
one. In case of accidental overdose, contact your healthcare provider
immediately.

Overdose

If you or anyone else take too much of REBOZEN DSR CAPSULE , contact your doctor
immediately or go to a hospital straight away. Overdosage symptoms are altered
consciousness, agitation, convulsions, disorientation, sleepiness and
extrapyramidal reactions (such as rigidity, tremor, drooling).

Side Effects Of REBOZEN DSR CAPSULE

Common side effects of REBOZEN DSR CAPSULE:

• headache
• dry mouth
• abdominal discomfort
• constipation
• dizziness
• nausea

When to Seek Medical Attention

Stop using REBOZEN DSR CAPSULE and seek medical attention immediately if you
experience symptoms such as allergic rash, facial swelling, difficulty
breathing, severe diarrhea, or persistent fatigue. Seek urgent attention for
unusual muscle stiffness, tremors, or irregular heartbeat.

How to Manage Mild Side Effects

Drink plenty of water to avoid dehydration and practice balanced eating habits.
If you experience mild stomach discomfort, avoid spicy or acidic food. For dry
mouth, staying hydrated or chewing sugar-free gum can help. If symptoms persist
or worsen, consult your healthcare provider for guidance.

Warning & Precautions

!### Pregnancy

Consult your doctorConsult your doctor before using REBOZEN DSR CAPSULE during pregnancy.

!### Breastfeeding

Consult your doctorConsult your doctor before using REBOZEN DSR CAPSULE during breastfeeding women.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you experience sleepiness, confusion or
less control over your movements.

!### Alcohol

Consult your doctorAvoid consum
aggravate your existing condition.

!### Kidney

ContraindicatedREBOZEN DSR CAPSULE is not recommended for use in patients with kidney
impairment.

!### Liver

Consult your doctorREBOZEN DSR CAPSULE is not recommended for use in patients with moderate or
severe liver impairment and it should be used with caution in patients with
liver problems.

!### Allergy

ContraindicatedDo not take REBOZEN DSR CAPSULE if you are allergic to Domperidone or
Rabeprazole or any other ingredients of this medicine.

!### Heart Disease

ContraindicatedREBOZEN DSR CAPSULE is not recommended for use in patients with heart problems
such as prolongation of QT interval or congestive heart failure.

!### Use In Pediatrics

ContraindicatedREBOZEN DSR CAPSULE is not recommended for use in children and adolescents (aged
less than 18 years) due to lack of safety and effectiveness.

!### Use In Geriatrics

Use with CautionREBOZEN DSR CAPSULE should be taken with caution in elderly patients (aged 65
years or above).

Other Warnings for REBOZEN DSR CAPSULE

Before taking REBOZEN DSR CAPSULE , inform your physician if you:

• have osteoporosis
• have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
• are going to test Chromogr

Who should not take REBOZEN DSR CAPSULE

REBOZEN DSR CAPSULE is not recommended for use if you:

• have bloody stools or bleeding in the gut
• have blockage or tear in the intestines
• have severe fluid or electrolyte disturbances
• have prolactinoma
• have phenylketonuria
• have problem that causes low levels of potassium or magnesium or high levels of potassium in the blood
• have hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsor

Safety Advice

• Inform your doctor if you have liver, kidney, or cardiac conditions
• Consult your doctor before using this medicine during pregnancy or breastfeeding
• Avoid alcohol intake as it may reduce the capsule’s effectiveness
• Do not exceed the recommended dosage
• Long-term consum

Who Should Avoid Taking REBOZEN DSR CAPSULE

• Individuals with moderate to severe liver or kidney impairment
• Patients with existing heart conditions like irregular heartbeat or heart failure
• Children under 12 years of age
• People with severe electrolyte imbalance or prolactinoma

Diet and Lifestyle Advice

1. Hydration Habits:

Drink enough plain water throughout the day (6–8 glasses or about 2 liters) to
maintain o
caffeinated beverages with water or calming drinks like chamomile or ginger tea.
Avoid drinking large volumes of water immediately after meals, sip gently
between meals instead.

2. Sleep and Rest Routine:

Ensure at least 7–8 hours of quality sleep daily, as fatigue and irregular rest
can increase stomach acidity. Avoid lying flat immediately after eating, keep
your head slightly elevated using a wedge pillow or sleep with the upper bed end
raised by 6–8 inches to reduce backflow of acid.

Expert Tips for Acid Control Support1. Eat Smart and Early:

Large portions and rushed meals can increase pressure on the stomach, pushing
acid upward. Instead, eat smaller, more frequent meals and chew slowly. Avoid
heavy dinners or lying down within 2–3 hours of eating, which allows gravity to
naturally keep acid in the stomach.

2. Practice Meal Timing Discipline:

The body digests food best during the day. Try to make lunch your largest meal
and keep dinner light. Avoid midnight snacks and does not recline immediately
after eating. A short post-meal walk can help activate digestion before rest.

3. Improve Your Sleep Pattern:

Reflux symptoms tend to worsen at night. Specialists recommend raising the head
of your bed by 6–8 inches or using a wedge pillow to prevent backflow of stomach
contents. Sleeping on your left side can also help reduce reflux episodes. Aim
for 7–8 hours of sleep each night, as fatigue can increase acid sensitivity.

4. Keep Hydration Consistent:

Drink plain water throughout the day to neutralize stomach acid and aid
digestion. However, avoid gulping large quantities at once and skip carbonated,
caffeinated, or citrus-based drinks, which can increase acidity.

5. Maintain Healthy Weight and Posture:

Excess abdominal pressure contributes to reflux. Regular exercise, stretching,
or yoga supports better digestion and prevents acid buildup. Maintain upright
posture after meals and avoid tight clothing or belts that compress the abdomen.

Drug - Drug interaction

1. Medicines That May Cause Harmful Interactions:

• Antiviral drugs for HIV such as Atazanavir, Nelfinavir, Rilpivirine, and Saquinavir may lose effectiveness or lead to unwanted effects when taken with Rabeprazole
• Antifungal medicines like Ketoconazole, Itraconazole, Posaconazole, and Fluconazole can have altered absor
• Antibiotics such as Erythromycin, Levofloxacin, Azithromycin, Moxifloxacin, and Telithromycin may increase risk of heart rhythm changes when used with Domperidone
• Heart medicines (cardiac glycosides) including Digoxin should be used cautiously, as Rabeprazole may increase their levels and toxicity risk
• Psychotropic medicines such as Haloperidol, Diazepam, Phenytoin, and Citalopram can interact and intensify neurological side effects
• Blood thinners like Warfarin may have an increased bleeding risk; INR monitoring may be required during co-administration
• Anti-cancer or kinase inhibitor therapy (e.g., Dasatinib, Erlotinib, Gefitinib, Nilotinib) may have reduced absor
• Methotrexate, combining Rabeprazole with high doses of this medicine can raise methotrexate levels and increase side-effect risks

2. Medicines That May Influence Heart Rhythm or Electrolytes:

Avoid combining with drugs known to cause QT interval prolongation such as
Disopyramide, Amiodarone, Dolasetron, Cisapride, Pentamidine, or certain
antimalarial and antihistamine agents (Halofantrine, Mequitazine, Mizolastine).
They may enhance the cardiac side effects of Domperidone

Drug - Food interaction

• Limit caffeine, alcohol, and carbonated beverages, as they may intensify acidity and reduce the medicine’s effectiveness.
• Avoid iron and calcium supplements close to your capsule intake, take them 2 hours apart to maintain absor
• Long-term users should monitor vitamin B12 and magnesium levels through routine testing, as Rabeprazole may reduce their absor

Safe Practice Recommendations:

• Maintain a gap of at least 2 hours between REBOZEN DSR CAPSULE and other oral drugs unless prescribed otherwise
• Seek medical advice immediately if you observe irregular heartbeat, muscle cramps, or severe dizziness while on combination therapy
• Never alter prescribed medication schedules without consulting your doctor or pharmacist

Synopsis

Drug	:	Domperidone, Rabeprazole
Pharmacological Category	:	Dopamine antagonist, Proton pump inhibitor
Therapeutic Indication	:	Pe
Dosage Forms	:	Tablet, Capsule

More Information

Why REBOZEN DSR CAPSULE is Doctor-Recommended for “Digestive Balance.”

Digestive discomfort caused by acidity and reflux is often linked to two
simultaneous problems excess acid formation and slowed stomach movement.REBOZEN
DSR CAPSULE addresses both through a clinically trusted dual mech
Rabeprazole and Domperidone. Doctors recommend this capsule because it supports
digestive balance by managing acid levels and enhancing gastric motility,
offering smoother stomach function throughout the day.

“Did You Know?” Sidebar: Use small fact highlights like: “Over 70% of acidity cases are linked to late-night meals. Following early dinner routines may reduce reflux frequency”

• Over 70% of acidity cases are linked to nighttime eating habits, eating late dinners or snacks within two hours of bedtime significantly increases reflux risk. Having meals earlier in the evening can reduce acid backflow and discomfort.
• Meal timing matters: Studies show that eating dinner 3–4 hours before sleep supports better digestion and reduces nighttime acid episodes. Early dining allows the stomach to empty properly before lying down.
• Late-night meals affect sleep and metabolism: Research indicates that those who regularly eat after 9 p.m. experience disrupted sleep patterns, slower calorie burning, and more frequent heartburn sensations compared to early eaters.
• Fast eating can upset digestive balance: People who eat quickly swallow more air, which increases pressure in the stomach and raises the chance of acid discomfort. Chewing food slowly and mindfully can reduce symptoms and aid smoother digestion.
• Simple posture shifts help: Standing or staying upright after meals even for 15–20 minutes can minimize reflux frequency and relieve heaviness. Avoid lying flat immediately after eating.
• Diet quality counts:Frequent consum
• Hydration supports healthy acid balance:Drinking plain water throughout the day dilutes acid concentration naturally. However, sipping slowly instead of gulping helps avoid trapped air and bloating.

“REBOZEN DSR CAPSULE vs Razo D SR – Key Differences

Feature	REBOZEN DSR CAPSULE	Razo D SR Capsule
Composition	Rabeprazole (20 mg) + Domperidone (10 mg)	Rabeprazole (20 mg) + Domperidone (30 mg SR)
Form Type	Immediate-release combination capsule	Sustained-release capsule for longer activity
Mech
Primary Purpose	Short-term digestive aid for acute acidity, heartburn, and indigestion	Long-acting support for chronic or recurrent acidity and reflux symptoms
Where It Works Best	Suitable for patients experiencing occasional or meal-triggered acidity episodes	Recommended for individuals who need consistent acid control over extended periods
Onset of Action	Acts quickly, often within 1 hour of intake	Gradual onset with sustained relief lasting up to 24 hours
Duration of Action	Shorter duration may require more frequent dose adjustments	Extended duration due to sustained release of Domperidone
Frequency of Use	Taken once daily, before breakfast or as prescribed	Taken once daily before meals for 24-hour coverage
Ideal For	Individuals with irregular eating habits, short-term reflux, or acid flare-ups after meals	Individuals with persistent acidity, slow digestion, or need for long-term digestive balance
Prescribed Duration	Usually for 2–4 weeks, depending on severity	Commonly used for longer regimens (4–8 weeks or as advised)
Common Side Effects	Headache, mild diarrhea, flatulence, and dizziness	Headache, stomach cramps, constipation, and mild drowsiness
Drug Release Control	Immediate release – acts fast but wears off sooner	Sustained release – ensures steady absor
Doctor’s Advice	Often prescribed for quick relief from acid discomfort or after short-term gastric distress	Prescribed when long-term, continuous acid suppression and motility regulation are needed

FAQs About REBOZEN DSR CAPSULE

Q: Can REBOZEN DSR CAPSULE cause diarrhea?

A: Yes. REBOZEN DSR CAPSULE may cause diarrhea in some individuals. Keep
yourself hydrated by drinking plenty of fluids, oral electrolytes and juices. Do
not self-manage diarrhea if it persists for a longer period.

Q: Can REBOZEN DSR CAPSULE cause acid reflux?

A: No. REBOZEN DSR CAPSULE is used to manage Gastro-Esophageal Reflux Disease
(GERD) and does not cause acid reflux. If you experience any unusual symptoms
after taking the medicine, consult your doctor for advice.

Q: Can REBOZEN DSR CAPSULE cause kidney damage?

A: REBOZEN DSR CAPSULE may rarely cause damage to your kidneys (Ex. interstitial
nephritis). However, inform your doctor immediately if you experience any signs
of kidney damage such as dark urine, blood in urine, painful urination or lower
abdominal discomfort during management with this medicine.

Q: Can REBOZEN DSR CAPSULE be used in children?

A: No. REBOZEN DSR CAPSULE is not recommended for use in children and
adolescents (below 18 years) due to lack of safety and effectiveness. Consult
your child’s doctor if your child experiences any symptoms of gastro-esophageal
reflux disease or pe
stomach, stomach pain, heartburn, burping).

Q: When should you take REBOZEN DSR CAPSULE before or after food?

A: According to leading clinical and pharmacy guidance , REBOZEN DSR
CAPSULE should be taken 30 minutes before food, typically before breakfast or
your first meal of the day, for o

Q: Is it safe to use REBOZEN DSR CAPSULE daily?

A: REBOZEN DSR CAPSULE is generally safe for daily use when taken under medical
supervision, but its long-term intake should always be reviewed and monitored by
a healthcare professional.

Q: Can I take REBOZEN DSR CAPSULE with antibiotics/antidepressants?

A: REBOZEN DSR CAPSULE can interact with
several antibiotics and anti-depressants, caution and doctor guidance are
important when using these together.

Q: Is REBOZEN DSR CAPSULE safe with thyroid or diabetes medication?

A: REBOZEN DSR CAPSULE can be generally used safely with thyroid and diabetes
medications, but care and timing are important to avoid interactions and ensure
o

Q: Should I avoid alcohol or coffee while using REBOZEN DSR CAPSULE?

A: Drinking alcohol or coffee while taking REBOZEN DSR CAPSULE is generally
advised against due to several reasons related to safety and medicine
effectiveness.

Useful Diagnostic Tests

• Complete Blood Count (CBC)
• Stool Complete Analysis