Lignox 2% Injection 30ml

Introduction About LIGNOX 2% INJECTION

LIGNOX 2% INJECTION contains Lignocaine, which belongs to the group of medicines
called Local anaesthetic agents. It is used to cause numbness (loss of
sensation) of body parts in the regions where it has been administered (local
anesthesia). It is generally used prior to spinal anesthesia or before surgical
procedures to cause a temporary loss of sensation. It also helps to control the
heartbeat in patients with arrythmia (an irregular heartbeat).

LIGNOX 2% INJECTION will be given to you only by a trained anaesthesiologist
around the areas (such as hands, legs, abdomen, pelvis, and spine) locally where
loss of sensation (numbness) is required.

Before receiving LIGNOX 2% INJECTION, inform your doctor if you have any liver,
kidney, or heart problems. You must also inform your doctor if you have any
breathing disorders, blood problems, epilepsy, glaucoma, stroke, dehydration,
low blood potassium levels, or muscle weakness.

LIGNOX 2% INJECTION should be used in pregnant or breastfeeding women only if
considered necessary by the physician. The most common side effects of receiving
LIGNOX 2% INJECTION are nausea, slow heart rate, dizziness, lower back pain,
difficulty walking, and an inability to control urine or bowel movements. Inform
your doctor if any of these side effects worsen.

Uses Of LIGNOX 2% INJECTION

• Causes numbness of body parts when used prior to spinal anesthesia or surgical procedures
• To manage arrythmia (an irregular heartbeat)

How LIGNOX 2% INJECTION Works

LIGNOX 2% INJECTION is an anaesthetic agent. It reduces pain sensation and
causes numbness in body parts by blocking the flow of certain ions (sodium ions)
through the nerves that cause pain sensation. As a result, it limits the
transfer of pain signals from the peripheral parts of the body (i.e., the face,
hands, legs, abdomen, and pelvis) to the brain, which leads to a loss of
sensation. It also normalizes heart rate by blocking the generation of abnormal
electrical signals in the heart.

How to use LIGNOX 2% INJECTION

LIGNOX 2% INJECTION will be given to you only by a doctor or by a trained
anaesthesiologist. Your doctor or anaesthesiologist will decide the correct dose
and site of administration for you depending upon your age, body weight, health
condition, and the type of nerve block that is required to provide anesthesia or
pain relief.

It can be administered locally to the region where loss of sensation (numbness)
is required or can be administered in a vein, around the spinal cord, or a nerve
to cause numbness during surgeries (caesarean section or other major surgeries)
to stop pain sensation.

Side Effects Of LIGNOX 2% INJECTION

Common

• pain at the site of the injection
• low blood pressure causing dizziness, drowsiness, or light-headedness
• nausea, vomiting
• tingling or pricking sensation (pins and needles)
• slow heartbeat, feeling faint
• changes in vision, blurred vision
• difficulty in passing urine
• pain or numbness in the legs or back
• unable to walk properly
• problems in controlling the bowels and bladder

Consult your doctor immediately if you experience any of the following side
effects after receiving LIGNOX 2% INJECTION:

• signs of severe allergic reactions (such as skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue, and/or throat with difficulty breathing or swallowing)
• blood problems (causing bluish discoloration of the skin, headache, tiredness, weakness, and shortness of breath)
• fits or convulsions

How To Manage Side Effects

!### Dizziness Or Drowsiness

Avoid standing or walking after surgery. Try to rest and relax. Get enough
sleep. Consult your doctor if you continue to feel dizzy for a prolonged period
of time.

!### Injection Site Reactions

Place an ice pack on the injected site. Do not move the affected area
frequently. If the symptom worsens, consult your doctor.

Warning & Precautions

!### Pregnancy

Consult your doctorLIGNOX 2% INJECTION should be used in pregnant women only if it is considered
necessary by the physician. Therefore, inform your doctor if you are pregnant or
think you may be pregnant before receiving LIGNOX 2% INJECTION.

!### Breastfeeding

Consult your doctorLIGNOX 2% INJECTION should be used for breastfeeding women only if it is
considered necessary by the physician. Therefore, inform your doctor before
receiving LIGNOX 2% INJECTION if you are breastfeeding.

!### Driving and Using Machines

Use with CautionLIGNOX 2% INJECTION may make you feel dizzy or drowsy for some time after
administration. Therefore, do not drive or operate any heavy tools or machines
if your abilities are affected by LIGNOX 2% INJECTION.

!### Alcohol

Consult your doctorAvoid the consum

!### Kidney

Use with CautionLIGNOX 2% INJECTION should be used with caution in patients with kidney
problems. Therefore, consult your doctor before receiving it.

!### Liver

Use with CautionLIGNOX 2% INJECTION should be used with caution in patients with liver problems.
Therefore, consult your doctor before receiving it.

!### Allergy

ContraindicatedInform your doctor before receiving LIGNOX 2% INJECTION if you are allergic to
lignocaine or to any other local anaesthetics (such as bupivacaine).

!### Lungs

Use with CautionLIGNOX 2% INJECTION should be used with caution in patients with breathing
disorders (such as asthma or COPD). Therefore, consult your doctor before
receiving it.

Heart Disease

Consult your doctorLIGNOX 2% INJECTION is not recommended for use in patients with heart diseases
(such as heart block, an abnormal heartbeat, or a very slow heartbeat). It
should be used with caution in patients with other heart disorders. Therefore,
consult your doctor before receiving it.

!### Use In Pediatrics

Consult your doctorLIGNOX 2% INJECTION should be used in children and adolescents (aged below 18
years) only if it is considered necessary by the physician. It is not
recommended for use in neonates aged less than 1 month. Therefore, consult your
doctor for advice before administration.

!### Use In Geriatrics

Use with CautionLIGNOX 2% INJECTION should be used with caution with elderly patients.
Therefore, consult your doctor for advice before receiving it.

Others

LIGNOX 2% INJECTION is not recommended for use if you:

• have low blood volume
• have porphyria (an inherited blood disorder)

Before receiving LIGNOX 2% INJECTION, inform your physician if you:

• are feeling sick or tired for no reason
• have epilepsy (fits)
• have glaucoma
• have low potassium levels in the blood, causing muscle cramps and constipation
• recently had vomiting, diarrhea, or excessive blood loss
• are not drinking enough amount of water
• have too much acidity in the blood
• have any skin infection (with pus) in and around the areas where the medicine is planned to be administered
• have problems thinking or reasoning
• have myasthenia gravis (severe muscle weakness or tenderness)
• have stroke
• have an imbalance in the constituents of the blood
• have a blood disorder

Interactions

A. Drug-Drug interactions:

Before receiving LIGNOX 2% INJECTION, inform your doctor if you are receiving
any of the following medicines:

• halothane (used to cause unconsciousness before a surgical procedure)
• medicines used to manage heart problems such as hypertension, angina, or abnormal heart rate (Ex. atenolol, propranolol, verapamil, amlodipine, nifedipine, amiodarone, and mexiletine)
• diuretics (used to reduce edema and blood pressure) Ex. furosemide, spironolactone, and hydrochlorothiazide
• medicines used to manage HIV infection (Ex. ritonavir, nelfinavir)
• medicines used to manage psychotic disorders (such as chlorpromazine, pimozide, sertindole, olanzapine, quetiapine, and zotepine)
• suxamethonium (used to relax muscles)
• opioid analgesics (used for pain relief) Ex. morphine, pethidine, and fentanyl
• dolasetron (used to manage nausea and vomiting)
• cimetidine (used to manage heartburn and stomach ulcers)
• acetazolamide (used to manage increased eye pressure)
• quinupristin and dalfopristin (used to manage bacterial infections)
• oral contrace

Overdosage:

LIGNOX 2% INJECTION will be administered to you only by a doctor or a nurse in a
hospital, and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms. Symptoms of overdosage
might include lightheadedness, numbness of the tongue, or a ringing sound in the
ears.

Synopsis

Drug	:	Lignocaine
Pharmacological Category	:	Voltage Gated Sodium Channel Blockers
Therapeutic Indication	:	Local anesthesia, Arrythmia
Dosage Forms	:	Injection, Gel, Cream, Ointment, Jelly, Topical Solution, Spray, Oral solution, Plaster

More Information

• Keep LIGNOX 2% INJECTION out of reach of children
• Store LIGNOX 2% INJECTION at room temperature

FAQs About LIGNOX 2% INJECTION

Q: How long will it take for LIGNOX 2% INJECTION to induce numbness?

A: It may take around 2–5 minutes for LIGNOX 2% INJECTION to create numbness in
body parts. However, this period may vary from person-to-person based on the
dose and amount of the LIGNOX 2% INJECTION that is administered to you.

Q: Is LIGNOX 2% INJECTION a narcotic medicine?

A: No. LIGNOX 2% INJECTION is not a narcotic. It is a local anaesthetic agent
that is used to create a loss of sensation (numbness) in certain body parts
following administration.

Q: Can LIGNOX 2% INJECTION affect blood pressure?

A: Yes. LIGNOX 2% INJECTION may cause changes in blood pressure (high or low
blood pressure), so if you experience any unusual symptoms, like feeling
extremely dizzy or lightheaded after receiving LIGNOX 2% INJECTION, consult your
doctor.

Q: What are the common side effects of LIGNOX 2% INJECTION?

A: The most common side effects of receiving LIGNOX 2% INJECTION are nausea,
slow heart rate, dizziness, lower back pain, difficulty walking, and an
inability to control urine or bowel movements. Inform your doctor if any of
these side effects worsen.

Q: What are the symptoms that could appear if I received an excessive amount
of LIGNOX 2% INJECTION?

A: LIGNOX 2% INJECTION will be administered to you only by a doctor or a nurse
in a hospital, and so it is unlikely to receive an overdose. However, consult
your doctor or nurse if you experience any unusual symptoms. Symptoms of
overdosage might include light-headedness, numbness of the tongue, or a ringing
sound in the ears.

Q: Can LIGNOX 2% INJECTION be used with children?

A: Yes. LIGNOX 2% INJECTION is used in children and in adolescents (aged between
18 years) only if it is considered necessary by the physician. It is not
recommended for use in neonates aged below 1 month due to a lack of safety data.

Q: Can LIGNOX 2% INJECTION cause nerve damage?

A: Yes. LIGNOX 2% INJECTION may cause nerve damage when administered in excess.
Therefore, inform your doctor if you experience signs of nerve damage (such as
tingling in the hands and feet) while receiving LIGNOX 2% INJECTION.

Q: Is LIGNOX 2% INJECTION safe for use by pregnant women?

A: LIGNOX 2% INJECTION should be used in pregnant women only if it is considered
necessary by the physician. Therefore, inform your doctor if you are pregnant or
think you may be pregnant before receiving LIGNOX 2% INJECTION.

Q: How long do the effects of LIGNOX 2% INJECTION last in the body?

A: The effects of LIGNOX 2% INJECTION may last about 10–20 minutes after
intravenous administration and for about 60–90 minutes after intramuscular
administration. However, the recovery period may vary from person-to-person
based on the dose and amount of the LIGNOX 2% INJECTION that is administered to
you.