Critifol 1% Infusion 50ml

Introduction About CRITIFOL 1% INFUSION

CRITIFOL 1% INFUSION contains Propofol which belongs to the group of medicines
called General Anaesthetic agents. It is used to cause partial or complete loss
of consciousness in patients so that surgical procedures can be performed.
Unconsciousness caused by propofol is completely reversed once the effect of the
medicine wears off. It can also be used to induce sleep in patients receiving
artificial respiration in an Intensive Care Unit (ICU).

CRITIFOL 1% INFUSION will be given to you only by a doctor or by a trained
anesthesiologist into the vein (intravenously). It is suitable for use both in
adults and in children (aged 1 month or older). It is mostly used in combination
with other local anaesthetics to achieve faster results.

Before receiving CRITIFOL 1% INFUSION inform your doctor if you have any liver,
kidney or heart problems. You must also inform your doctor if you have fits,
high blood cholesterol levels or dehydration as a precaution.

CRITIFOL 1% INFUSION is not recommended for use in pregnant women unless
considered necessary by the physician. Breastfeeding should be stopped for 24
hours or until the effect of the medicine completely wears off, as this medicine
may pass to the nursing infant through the breast milk.

The most common side effects of receiving CRITIFOL 1% INFUSION are pain,
swelling and redness at the site of injection, low blood pressure, slow
heartbeat, nausea, vomiting, headache and flushing. Consult your doctor if any
of these side effect worsens.

Uses Of CRITIFOL 1% INFUSION

• Used to cause partial or complete loss of consciousness prior to surgical procedures
• Induces sleep in patients receiving artificial respiration in an Intensive Care Unit (ICU)

How CRITIFOL 1% INFUSION Works

CRITIFOL 1% INFUSION is a general anaesthetic agent. It produces loss of
consciousness by potentiating the actions of certain brain chemicals (GABA) any
by decreasing the flow of certain ions (chloride) across the nerve cells that is
required to maintain alertness.

How to use CRITIFOL 1% INFUSION

CRITIFOL 1% INFUSION will be given to you only by a doctor or by a trained
anesthesiologist into the vein (intravenously).

Your doctor/ anesthesiologist will decide the correct dose for you depending
upon the age, body weight and disease condition.

Side Effects Of CRITIFOL 1% INFUSION

Common

• injection site reactions (such as pain, redness and swelling)
• low blood pressure
• changes in breathing pattern
• slow heartbeat
• nausea, vomiting
• headache
• withdrawal symptoms (such as abnormal behaviour, increased sweating, shakiness and anxiety)
• flushing

Rare

• twitching and shaking of body
• fits
• unusual colour of urine

How To Manage Side Effects

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

Injection Site Reactions

Place an ice pack on the injected site. Do not move the affected area
frequently. If the symptom worsens, consult your doctor.

!### Nausea And Vomiting

Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if
nausea worsens.

Warning & Precautions

!### Pregnancy

ContraindicatedCRITIFOL 1% INFUSION is not recommended for use in pregnant women unless
considered necessary by the physician. Therefore, inform your doctor before
receiving it.

!### Breastfeeding

ContraindicatedBreastfeeding should be stopped for 24 hours or until the effect of the medicine
completely wears off, as this medicine may pass to the nursing infant through
the breast milk.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines until the effects of the
medicine complete wears off

!### Alcohol

Consult your doctorAvoid consum

!### Kidney

Use with CautionCRITIFOL 1% INFUSION should be used with caution in patients with kidney
problems. Therefore, consult your doctor before receiving it.

!### Liver

Use with CautionCRITIFOL 1% INFUSION should be used with caution in patients with liver
problems. Therefore, consult your doctor before receiving it.

!### Allergy

ContraindicatedInform your doctor before receiving CRITIFOL 1% INFUSION, if you are allergic to
Propofol.

!### Lungs

Use with CautionCRITIFOL 1% INFUSION should be used with caution in patients with breathing
disorders (such as asthma or COPD). Therefore, consult your doctor before
receiving it.

!### Heart Disease

Use with CautionCRITIFOL 1% INFUSION should be used with caution in patients with heart
disorders. Therefore, consult your doctor before receiving it.

Others

Before receiving CRITIFOL 1% INFUSION, inform your physician if you:

• ever had epilepsy (fits)
• have high blood cholesterol levels
• are dehydrated
• have mitochondrial diseases
• are generally unwell

Use in pediatrics:

CRITIFOL 1% INFUSION should be used in children and adolescents (aged below 18
years) only if it is considered necessary by the physician. It is not
recommended for use in neonates aged less than 1 month. Therefore, consult your
doctor for advice before administration.

Use in geriatrics:

CRITIFOL 1% INFUSION should be used with caution in the elderly patients.
Therefore, consult your doctor for advice before receiving it.

Interactions

A. Drug-Drug interactions:

Before receiving CRITIFOL 1% INFUSION, inform your doctor if you are receiving
any of the following medicines:

• Rifampicin (a medicine used to manage tuberculosis)

Overdosage:

CRITIFOL 1% INFUSION will be administered to you only by a doctor or a nurse in
a hospital, and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Propofol
Pharmacological Category	:	Fast Acting Intravenous anesthetics
Therapeutic Indication	:	General Anaesthesia
Dosage Forms	:	Injection, Infusion

More Information

• Keep CRITIFOL 1% INFUSION out of reach of children
• Store CRITIFOL 1% INFUSION at room temperature

FAQs About CRITIFOL 1% INFUSION

Q: What is the use of CRITIFOL 1% INFUSION?

A: CRITIFOL 1% INFUSION is used to cause partial or complete loss of
consciousness in patients so that surgical procedures can be performed. It can
also be used to induce sleep in patients receiving artificial respiration in an
Intensive Care Unit (ICU).

Q: How long will it take for the effects of CRITIFOL 1% INFUSION to wear
off?

A: The effect of CRITIFOL 1% INFUSION may wear off after 24 hours. However, this
period may vary from person-to-person based on the dose administered.

Q: Can CRITIFOL 1% INFUSION be used in children?

A: CRITIFOL 1% INFUSION should be used in children and adolescents (aged below
18 years) only if it is considered necessary by the physician. It is not
recommended for use in neonates aged less than 1 month. Therefore, consult your
doctor for advice before administration.

Q: What are the side effects of receiving CRITIFOL 1% INFUSION?

A: The most common side effects of receiving CRITIFOL 1% INFUSION are pain,
swelling and redness at the site of injection, low blood pressure, slow
heartbeat, nausea, vomiting, headache and flushing. Consult your doctor if any
of these side effect worsens.

Q: Can CRITIFOL 1% INFUSION be used during pregnancy?

A: CRITIFOL 1% INFUSION is not recommended for use in pregnant women unless
considered necessary by the physician. Therefore, inform your doctor before
receiving it.