Lamivir 300mg Syrup 100ml

Introduction About LAMIVIR 300MG SYRUP

LAMIVIR 300MG SYRUP contains Lamivudine which belongs to a group of medicines
called Anti-viral drugs. It is used to manage Human Immunodeficiency Virus (HIV)
infection in adults and children.

HIV is the virus that causes Acquired Immune Deficiency Syndrome (AIDS) and
other related illness. Signs and symptoms include fever, headache, muscle aches
and joint pain, rash, sore throat and painful mouth sores, swollen lymph glands,
mainly on the neck, diarrhea, weight loss, cough and night sweats.

LAMIVIR 300MG SYRUP is not recommended for use in pregnant women unless it is
considered clearly necessary. It is not recommended for use in breastfeeding
women as it passes into breast milk. Consult your doctor before taking it.

LAMIVIR 300MG SYRUP should be used with caution in patients with liver disease,
kidney problem, diabetes, pancreatitis. Consult your doctor before taking it.

LAMIVIR 300MG SYRUP should be used with caution in children with kidney problem.
It should be used with caution in elderly patients. Consult your doctor before
taking it.

The most common side effects of taking LAMIVIR 300MG SYRUP are headache, nausea,
vomiting, stomach pain, diarrhea, tiredness, fever, etc. Contact your doctor if
any of the symptoms worsen.

Uses Of LAMIVIR 300MG SYRUP

• To manage HIV infection

How LAMIVIR 300MG SYRUP Works

LAMIVIR 300MG SYRUP inhibits the activity of enzyme (HIV-1 reverse
transcriptase) which is responsible for virus replication. Thus, it helps to
decrease the amount of HIV in the body.

How to use LAMIVIR 300MG SYRUP

Take LAMIVIR 300MG SYRUP as advised by your physician. Shake well before use. It
can be taken with or without food. Your doctor will decide the correct dose of
LAMIVIR 300MG SYRUP and duration for you depending upon your age, body weight
and disease condition. Do not stop taking LAMIVIR 300MG SYRUP unless your doctor
advice you to stop.

Side Effects Of LAMIVIR 300MG SYRUP

Common

• headache
• nausea, vomiting, diarrhoea, stomach pain
• tiredness, lack of energy
• fever
• feeling generally unwell
• muscle pain and discomfort, joint pain
• difficulty in sleeping
• cough, irritated or runny nose
• rash
• alopecia (hair loss)

Rare

• breakdown of muscle tissue

Stop taking LAMIVIR 300MG SYRUP and consult with your doctor if you experience
any of the following:

• serious allergic reaction such as skin rash, hives, swelling of the face, tongue or throat leading to difficulty in swallowing or breathing, chest pain
• signs and symptoms of lactic acidosis such as feel very weak or tired, unusual muscle pain, difficulty in breathing, stomach pain, nausea and vomiting, feel cold, especially in your arms and legs, feel dizzy or light-headed, fast or irregular heartbeat
• signs and symptoms of liver disease such as yellowish discolouration of skin or the white part of your eyes (jaundice), dark or tea-coloured urine, light-coloured stools, loss of appetite, nausea, vomiting, pain or tenderness on the right side of your stomach area
• signs and symptoms of pancreatitis such as severe upper stomach-area pain, with or without nausea and vomiting

How To Manage Side Effects

Headache:

Rest and relax. Drink plenty of fluids such as water or ORS (Oral Rehydrating
Solution) and apply a pain-relieving balm on the head if necessary. Contact your
doctor if your headache did not improve.

Nausea and vomiting:

Take the medicine, with or just after a meal. Stick to simple meals. Avoid
eating oily or spicy food. Contact your doctor if your nausea and vomiting did
not improve.

Stomach pain:

Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on
your stomach. Contact your doctor if your stomach pain worsens.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated.
Do not take any medicine on your own for managing diarrhoea. Contact your doctor
if your diarrhoea did not improve.

Warning & Precautions

!### Pregnancy

LAMIVIR 300MG SYRUP is not recommended for use in pregnant women unless it is
considered clearly necessary. Consult your doctor before taking it.

!### Breastfeeding

Women who are HIV-positive must not breast-feed, because HIV infection can be
passed on to the baby in breast milk. A small amount of the ingredients in
LAMIVIR 300MG SYRUP can also pass into your breast milk. Hence, nursing mothers
must not breastfeed their infants while taking LAMIVIR 300MG SYRUP. Contact your
doctor immediately if you’re breast-feeding or thinking about breast-feeding.

!### Driving and Using Machines

LAMIVIR 300MG SYRUP is unlikely to affect your ability to drive or use machines.
Consult your doctor before taking it.

!### Kidney

LAMIVIR 300MG SYRUP should be used with caution in patients with kidney problem
and may require dose adjustment. Consult your doctor before taking it.

!### Liver

LAMIVIR 300MG SYRUP should be used with caution if you had liver disease,
including hepatitis B or C. Consult your doctor before taking it.

!### Allergy

Do not take LAMIVIR 300MG SYRUP if you are allergic to lamivudine or any of the
other ingredients of this medicine.

Others

Before taking LAMIVIR 300MG SYRUP, inform your doctor if you:

• are seriously overweight (especially women)
• have diabetes
• have pancreatitis
• have intolerance to sugars

Use inpediatrics:

LAMIVIR 300MG SYRUP should be used with caution in children with kidney problem.
Consult your doctor before taking it.

Use in geriatrics:

LAMIVIR 300MG SYRUP should be used with caution in elderly patients. Consult
your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking LAMIVIR 300MG SYRUP, inform your doctor if you are taking any of
the following medicine:

• medicines (generally liquids) containing sorbitol and other sugar alcohols (Ex. xylitol, mannitol, lactitol or maltitol)
• other medicines containing lamivudine (used to manage HIV infection or hepatitis B infection) Ex. dolutegravir and lamivudine, tenofovir and lamivudine
• emtricitabine (used to manage HIV infection)
• co-trimoxazole (used to manage infections)
• cladribine (used to manage hairy cell leukaemia- a type of bone marrow cancer)
• interferon alfa, ribavirin (medicines used to manage hepatitis B & C)

Overdose:

If you or anyone else accidentally take too much of LAMIVIR 300MG SYRUP, contact
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Lamivudine
Pharmacological Category	:	Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs)
Therapeutic Indication	:	HIV infection
Dosage Forms	:	Tablet, Solution

More Information

• Keep LAMIVIR 300MG SYRUP out of the sight and reach of children
• Store LAMIVIR 300MG SYRUP below 30°C

FAQs About LAMIVIR 300MG SYRUP

DoesLAMIVIR 300MG SYRUPmanage HIV infection?

LAMIVIR 300MG SYRUP does not completely manage HIV infection; it reduces the
amount of virus in your body and keeps a check at it. It also increases the CD4
cell count (important in fighting infection) in your blood.

What does LAMIVIR 300MG SYRUP do to the body?

LAMIVIR 300MG SYRUP inhibits the activity of enzyme (HIV-1 reverse
transcriptase) which is responsible for virus replication. Thus, it helps to
decrease the amount of HIV in the body.

How often do you take LAMIVIR 300MG SYRUP?

Take LAMIVIR 300MG SYRUP according to the physician advice. Generally, it is
used once or twice daily. Your doctor will decide the correct dose and duration
for you depending upon your age, body weight and disease condition.

Does LAMIVIR 300MG SYRUP cause liver damage?

Yes, LAMIVIR 300MG SYRUP is rarely associated with liver damage. Stop taking the
medicine and contact your doctor immediately if you experience signs and
symptoms of liver disease such as yellowish discolouration of skin or the white
part of your eyes (jaundice), dark or tea-coloured urine, light-coloured stools,
loss of appetite, nausea, vomiting, pain or tenderness on the right side of your
stomach area.

IsLAMIVIR 300MG SYRUPsafe in pregnancy?

LAMIVIR 300MG SYRUP is not recommended for use in pregnant women unless it is
considered clearly necessary. It may cause side effects in unborn babies. If you
have taken LAMIVIR 300MG SYRUP during your pregnancy, your doctor may take
regular blood tests and other diagnostic tests to monitor the development of
your child. Consult your doctor before taking it.

Can I pass HIV to other people while taking LAMIVIR 300MG SYRUP?

HIV infection is spread by sexual contact with infected person or by transfer of
infected blood (for example, by sharing injection needles). You can still pass
on HIV when taking LAMIVIR 300MG SYRUP, although the risk is lowered by
effective antiretroviral management. Consult your doctor regarding the
precautions needed to avoid passing the infection to other people.

Useful Diagnostic Tests

• Liver Function Test
• Complete Blood Count (CBC)
• Lipid profile test
• Viral Load Test
• CD4 Count Test