CIPMIDO 5mg Tablet 30's

Introduction About CIPMIDO 5MG TABLET

CIPMIDO 5MG TABLET contains Midodrine which belongs to the group of medicines
called Alpha -1 Selective Adrenergic Receptor Agonist. It is used to manage low
blood pressure (hypotension) in adults. Symptoms of low blood pressure include
blurred or fading vision, dizziness or light-headedness, fainting, feeling sick,
difficult in concentrating.

Midodrine acts on the blood vessels via the sympathetic nervous system (part of
nervous system that cause increase in heart rate, blood pressure, breathing
rate, and dilatation of pupil) to correct imbalances of blood distribution, such
as preventing too much blood pooling in the legs when standing up which may
cause low blood pressure. Your doctor may regularly monitor the blood pressure
when you are lying down and when you are standing up as there may be a risk of
your blood pressure rising when you lie down (Ex. at night).

CIPMIDO 5MG TABLET is not recommended for use in patients having severe heart
disease.CIPMIDO 5MG TABLET should be used with caution in patient having severe
kidney disease, liver problems. Consult your doctor for advice before
takingCIPMIDO 5MG TABLET, if you are pregnant or breast-feeding.CIPMIDO 5MG
TABLET is not recommended for use in children and adolescents below the age of
18 years. The most common side effects of takingCIPMIDO 5MG TABLET are increased
blood pressure when lying down, headache, nausea (feeling sick), vomiting,
heartburn. Consult your doctor if the symptom worsens.

Uses Of CIPMIDO 5MG TABLET

• Used to manage certain severe forms of low blood pressure in adults by increasing the blood pressure

How CIPMIDO 5MG TABLET Works

CIPMIDO 5MG TABLET acts on the blood vessels via the sympathetic nervous system
(part of nervous system that cause increase in heart rate, blood pressure,
breathing rate, and dilatation of pupil) to correct the imbalances of blood
distribution, such as preventing too much blood pooling in the legs when
standing up which may cause low blood pressure.

How to use CIPMIDO 5MG TABLET

TakeCIPMIDO 5MG TABLET as advised by your physician. Swallow this medicine, do
not crush, or chew the medicine. Your doctor will decide the correct dose and
duration for you depending upon your age, body weight and disease condition.

Side Effects Of CIPMIDO 5MG TABLET

Common

• Pain when urinating
• Tingling and itching
• Increased blood pressure when lying down
• Headache
• Nausea (feeling sick), vomiting
• Heartburn
• Inflammation of the lining inside the mouth
• Flushing
• Rash
• Chills
• Difficulty in urinating

Uncommon

• Sleep disturbances including difficulty sleeping
• Restlessness
• Agitation (state of anxiety), irritability
• Slowed heart rate
• Urge to urinate

Rare

• Rapid, irregular or fast heartbeat
• Chest pain
• Signs of increased liver enzymes such stomach pain, dark urine, fatigue (feeling tired), itching, jaundice (yellowing of your skin or eyes)
• Dizziness or light headedness
• Stroke
• Visual disturbances

How To Manage Side Effects

!### Dizziness Or Drowsiness

When you feel dizzy, lie or sit down immediately. If you're experiencing a
severe episode of vertigo, lie in a dark and quite place with eyes closed.
Driving should be avoided, if you experience frequent dizziness without warning.
Talk to your doctor if the symptom worsens.

Headache

Apply hot or cold-water bag on your head. Try taking rest in a quiet and dark
room. Massage with mild pressure on scalp or head.

!### Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid
eating oil rich or spicy foods, sugary snacks, and drinks. Avoid drinking too
much liquid along with your meals, drink slowly in between meals. Consult your
doctor if your symptom does not improve.

Warning & Precautions

!### Pregnancy

ContraindicatedCIPMIDO 5MG TABLET is not recommended for use in pregnant. Consult your doctor
before takingCIPMIDO 5MG TABLET.

!### Breastfeeding

ContraindicatedCIPMIDO 5MG TABLET is not recommended for use during breast-feeding. Discuss
with your doctor before takingCIPMIDO 5MG TABLET.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel dizzy or lightheaded after
takingCIPMIDO 5MG TABLET. Consult your doctor before takingCIPMIDO 5MG TABLET.

!### Kidney

ContraindicatedCIPMIDO 5MG TABLET is not recommended for use in patients with severe kidney
disease. Consult your doctor before takingCIPMIDO 5MG TABLET.

!### Liver

Use with CautionCIPMIDO 5MG TABLET should be used with caution in patients having liver
impairment. Consult your doctor before takingCIPMIDO 5MG TABLET.

!### Allergy

ContraindicatedCIPMIDO 5MG TABLET is not recommended for use if you are allergic to Midodrine.

!### Heart Disease

ContraindicatedCIPMIDO 5MG TABLET is not recommended for use in patients with severe heart
disease including slow pulse, heart attack, heart failure, heart rhythm
disorders, widening of the aorta (aortic aneurysm) or other cardiovascular
diseases and also in patients with high blood pressure, or a form of low blood
pressure known as vasovagal hypotension. Consult your doctor before
takingCIPMIDO 5MG TABLET.

!### Use In Pediatrics

ContraindicatedCIPMIDO 5MG TABLET is not recommended for use in children and adolescents (under
18 years of age). Consult your doctor before takingCIPMIDO 5MG TABLET.

!### Use In Geriatrics

Use with CautionCIPMIDO 5MG TABLET is used with caution in patients above 60 years of age.
Usually the management is initiated with the lowest dose and gradually increased
depending upon the clinical condition of the patient. Consult your doctor before
takingCIPMIDO 5MG TABLET.

Others

CIPMIDO 5MG TABLET is not recommended for use if you have:

• Difficulty in urinating
• Have elevated pressure in the eye (glaucoma) or poor vision because of diabetes
• Hyperthyroidism (overactive thyroid gland)
• Hormonal disorders caused by a tumour in the adrenal medulla (pheochromocytoma)
• Enlarged prostate

Before takingCIPMIDO 5MG TABLET, inform your doctor if you have:

• Serious disorder of the nervous system (autonomic nervous system disorders)
• Problems with blood circulation
• Disease of the prostate

Interactions

A. Drug-Drug interactions:

• Reserpine and guanethidine (medicines used to reduce high blood pressure)
• Antihistamines like cetirizine, chlorpheniramine (used to manage allergies)
• Hormones for the thyroid like thyroxine
• Tricyclic antidepressants like clomipramine, amoxapine, amitriptyline and MAO-inhibitors such as selegiline, isocarboxazid, phenelzine, (both used to manage depression)
• Vasoconstrictors like epinephrine, dopamine, phenyl epinephrine (medicines that narrow blood vessels)
• Sympathomimetic agents such as ephedrine, isoproterenol, metaproterenol, (medicines that have a stimulating effect on certain parts of the nervous system)
• Prazosin and phentolamine (medicines used to manage heart disease
• Digitalis preparations such as digitoxin, digoxin (medicines used to manage heart disease)
• Fludrocortisone acetate (medicine used to reduce inflammation)
• Perphenazine (medicine used to manage mental or mood disorders)
• Amiodarone (medicine used to manage irregular heartbeat)
• Metoclopramide (medicine used to prevent vomiting)

Overdosage:

If you or anyone else accidentally take too much ofCIPMIDO 5MG TABLET, consult
your doctor immediately or visit the nearby hospital. The most common symptoms
of overdose are high blood pressure (hypertension), slow heart rate
(bradycardia), difficulty urinating and feeling of coldness.

Synopsis

Drug	:	Midodrine
Pharmacological Category	:	Alpha -1 Selective Adrenergic Receptor Agonist
Therapeutic Indication	:	Low blood pressure
Dosage Forms	:	Tablet

More Information

Storage

• KeepCIPMIDO 5MG TABLET out of reach of children
• Store at room temperature

FAQs About CIPMIDO 5MG TABLET

Q: CanCIPMIDO 5MG TABLET cause heart palpitations?

A: Yes,CIPMIDO 5MG TABLET may cause irregular and fast heartbeat as it is one of
the side effects of this medicine. This may result in the risk of falling down.
Other symptoms include blurred vision, weakness, or tiredness, feeling sick.
Consult your doctor immediately if you experience any abnormal heartbeat or
signs of abnormal heartbeat (such as chest pain, dizziness, fainting).

Q: How doesCIPMIDO 5MG TABLET works?

A: CIPMIDO 5MG TABLET acts on the blood vessels via the sympathetic nervous
system (part of nervous system that cause increase in heart rate, blood
pressure, breathing rate, and dilatation of pupil) to correct the imbalances of
blood distribution, such as preventing too much blood pooling in the legs when
standing up which may cause low blood pressure.

Q: Is it safe to useCIPMIDO 5MG TABLET in older patients?

A: Yes, but it should be used with caution in elderly with regular monitoring of
blood pressure levels and your doctor may monitor your vital organs as it may
cause damage to liver, kidney, and heart.

Q: What happens if I stop takingCIPMIDO 5MG TABLET?

A: Do not stop takingCIPMIDO 5MG TABLET without talking to your doctor first.
Stopping this medicine suddenly can cause your blood pressure to fall and may
increase the risk of blurred vision, dizziness, fainting or death.

Q: Who should not takeCIPMIDO 5MG TABLET?

A: You should not useCIPMIDO 5MG TABLET if you have severe heart disease,
overactive thyroid, an adrenal gland tumour, kidney disease, heart disease,
liver disease, painful urination, or if your blood pressure is high even while
lying down. Consult your doctor immediately if you experience any unusual
effects.

Useful Diagnostic Tests

• Kidney function test