NOR 4mg Injection 2ml

Introduction About NOR 4MG INJECTION

NOR 4MG INJECTION contains Noradrenaline which belongs to the group of medicines
called Adrenergic and Dopaminergic agents. It is used in emergency conditions to
increase blood pressure to normal levels in adults. During NOR 4MG INJECTION
management, your doctor will monitor your blood pressure, blood volume, heart
rate and the infusion site.

NOR 4MG INJECTION is not recommended for use in patients with low blood pressure
caused by low blood volume. NOR 4MG INJECTION should be used with caution in
patients with liver, heart or kidney disease, blood clots, diabetes or over
active thyroid gland.

NOR 4MG INJECTION will be given in pregnancy only if clearly necessary as it may
cause harm to unborn baby. It is not known whether NOR 4MG INJECTION pass
through the breast milk so it should be used with caution.

The safety and efficacy of NOR 4MG INJECTION in children and adolescents under
18 years of age is not established so, contact your child’s doctor for advice.
The most common side effects of NOR 4MG INJECTION are low blood pressure, slow
heartbeat, anxiety, headache, etc. Call your doctor if any of the symptoms
worsen.

Uses Of NOR 4MG INJECTION

• Used in emergency conditions to increase blood pressure to normal levels

How NOR 4MG INJECTION Works

NOR 4MG INJECTION works by constricting the blood vessels, leading to increase
in blood pressure.

How to use NOR 4MG INJECTION

NOR 4MG INJECTION will be given to you only by a doctor or a nurse into a vein
as an intravenous infusion. Dose and duration will be decided by your physician
depending upon your age, body weight and disease condition.

Side Effects Of NOR 4MG INJECTION

Common

• high blood pressure, slow heartbeat
• lack of blood flow causing injury
• anxiety, headache
• breathing difficulty, excess fluid in the lungs
• blistering and tissue damage at injection site

Rare

Stop receiving NOR 4MG INJECTION and contact your doctor immediately if you
experience any of the following side effects:

• itchy rash (hives), swelling of the hands, feet, ankles, face, lips, mouth or throat causing difficulty in swallowing or breathing
• pain or swelling at injection site
• abnormal heart rhythm
• cold extremities or pain in the extremities

How To Manage Side Effects

Itchy skin:

Avoid hot showers because hot water can irritate the skin. Do not scratch the
affected area. Use sunscreen and protective clothing when outdoors. Use
moisturizers to soothe and hydrate the affected skin area. If symptom persists,
contact your doctor.

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on the head if required. Do not consume too much of alcohol.
If symptom persists, contact your doctor.

Warning & Precautions

!### Pregnancy

NOR 4MG INJECTION will be given in pregnancy only if clearly necessary as it may
cause harm to unborn baby. Consult your doctor for advice.

!### Breastfeeding

NOR 4MG INJECTION should be used with caution in breastfeeding women as it is
not known whether it passes through the breast milk. Consult your doctor for
advice.

!### Driving and Using Machines

Do not drive or operate any machines after receiving NOR 4MG INJECTION.

!### Kidney

NOR 4MG INJECTION should be used with caution in patients with severe kidney
disease. Contact your doctor for advice.

!### Liver

NOR 4MG INJECTION should be used with caution in patients with liver failure.
Contact your doctor for advice.

!### Allergy

Do not receive NOR 4MG INJECTION if you are allergic to Noradrenaline or any of
the other ingredients of this medicine.

!### Heart Disease

NOR 4MG INJECTION is not recommended for use in patients with low blood pressure
caused by low blood volume. NOR 4MG INJECTION should be used with caution in
patients with high blood pressure or blood clots or obstructions in the blood
vessels supplying the heart, low blood pressure following a heart attack,
Prinzmetal’s angina (a type of chest pain), left ventricular dysfunction, heart
attack or irregular heartbeat. Contact your doctor for advice.

Others

Before receiving NOR 4MG INJECTION, inform your doctor if you have:

• diabetes
• over-active thyroid
• low oxygen levels in the blood
• raised carbon dioxide levels in the blood
• increased pressure inside the brain
• clots or obstructions in the blood vessels supplying the intestines or other parts of the body

Use in Paediatrics:

NOR 4MG INJECTION is not recommended for use in children and adolescents under
18 years of age. Consult your child’s doctor for advice.

Use in Geriatrics:

Use NOR 4MG INJECTION with caution in elderly patients aged 65 years or above.
Consult your doctor for advice.

Interactions

A. Drug-Drug interactions:

Before receiving NOR 4MG INJECTION, inform your doctor if you are taking any of
the following medicines:

• medicines used for depression (Ex. fluoxetine, sertraline, selegiline, moclobemide, iproniazid, phenelzine, amitriptyline, nortriptyline, imipramine, desipramine, trimipramine)
• linezolid (used for bacterial infections)
• medicines used during surgery to numb the pain (Ex. halothane, cyclopropane, chloroform, enflurane, propofol)
• orciprenaline (medicine used in the management of asthma)
• dobutamine (medicine used for heart diseases)
• medicines used for high blood pressure (Ex. guanethidine, guanadrel, reserpine, methyldopa, prazosin, metoprolol, rauwolfia alkaloids)
• medicines used for irregular heartbeats (Ex. amiodarone, quinidine)
• cardiac glycosides like digoxin (used for heart failure)
• levodopa (medicine used for parkinson’s disease)
• medicines used for thyroid diseases (Ex. levothyroxine)
• oxytocin (medicine used to improve uterine contractions)
• medicines used for allergies (Ex. chlorpheniramine, cetirizine)
• amphetamine (used to increase wakefulness)
• doxapram (used for breathing disorders)
• mazindol (used to manage obesity)
• medicines used to manage migraine (Ex. ergotamine, dihydroergotamine)
• lithium (used to manage mental illness)

Overdosage:

NOR 4MG INJECTION will be administered to you only by a doctor or a nurse in a
hospital and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms like severely high blood
pressure, slow heartrate, severe headache, sensitivity to light, chest pain,
pale skin, high fever, intense sweating, vomiting or breathlessness.

Synopsis

Drug	:	Noradrenaline
Pharmacological Category	:	Adrenergic and Dopaminergic agent
Therapeutic Indication	:	Low blood pressure
Dosage Forms	:	Injection

More Information

• Keep NOR 4MG INJECTION out of reach of children
• Store NOR 4MG INJECTION below 25°C

FAQs About NOR 4MG INJECTION

What if I miss a dose of NOR 4MG INJECTION?

It is unlikely that you will miss a dose of NOR 4MG INJECTION, as it will be
given to you in hospital. However, please stick to the prescribed schedule as
agreed with your doctor for o
Tell your doctor whenever you miss to receive any dose.

Does anaesthesia affect NOR 4MG INJECTION use?

Using NOR 4MG INJECTION with propofol (an anaesthetic) may lead to propofol
infusion syndrome (PRIS), which is a serious condition that affects patients who
are being sedated with propofol during surgeries. Your doctor would observe
disorders in your body’s metabolism from blood tests.

Can NOR 4MG INJECTION be used in pregnancy?

NOR 4MG INJECTION may harm the unborn baby so, if you are pregnant, think you
may be pregnant or are planning for a baby, consult your doctor before receiving
it. Inform your doctor immediately if you become pregnant during management with
NOR 4MG INJECTION.

Can NOR 4MG INJECTION be given to children?

No. NOR 4MG INJECTION is used for adults and not recommended for children and
adolescents below 18 years of age. Consult your child’s doctor for advice. The
doctor will decide a proper dose or select a suitable alternative management for
your child.

Can I take other medicines with NOR 4MG INJECTION?

Before receiving NOR 4MG INJECTION, inform your doctor if you are taking, have
taken or might take any other medicine, including prescri
or any herbal medicine, as these might lead to significant side effects by
interacting with each other.

Useful Diagnostic Tests

• Echocardiogram