Caluran CP 50mg Tablet 30'S

Introduction About CALURAN CP 50MG TABLET

CALURAN CP 50MG TABLET contains Bicalutamide, which belongs to a group of
medicines called Anti-androgens. It is used in the management of prostate cancer
in adult male patients. Prostate cancer is a type of slow-growing cancer that
occurs in the cells of the prostate gland (a small walnut-shaped gland that
provides nourishment to sperm in males) that grows out of control and spreads to
other parts of the body.

Prostate cancer is characterized by symptoms such as troubled urination, blood
in urine, the urge to urinate frequently at night, blood in semen, bone pain,
losing weight without trying, pain while sitting, and erectile dysfunction.
During management with CALURAN CP 50MG TABLET, your doctor may perform blood
tests to check for any changes to your blood.

Avoid direct exposure to excessive sunlight or UV light while you are taking
CALURAN CP 50MG TABLET. Before taking CALURAN CP 50MG TABLET, inform your doctor
if you have any liver or heart problems or diabetes. CALURAN CP 50MG TABLET is
not recommended for use in women, including pregnant women or mothers who are
breast-feeding their babies.

CALURAN CP 50MG TABLET is also not recommended for use in children and
adolescents (less than 18 years of age). The most common side effects of taking
CALURAN CP 50MG TABLET are skin rash, breast swelling or tenderness, weakness,
loss of appetite, dizziness, sleepiness, nausea, etc. Call your doctor if any of
the symptoms get worse over time.

Uses Of CALURAN CP 50MG TABLET

• To manage prostate cancer in adult male patients

How CALURAN CP 50MG TABLET Works

CALURAN CP 50MG TABLET inhibits cell growth and manages the spread of cancer
cells from the prostate gland to other parts of the body by selectively blocking
proteins responsible for the growth and development of the prostate gland
(androgen receptors), which reduces the effect of androgen (the male sex
hormone) in the prostate gland.

How to use CALURAN CP 50MG TABLET

Take CALURAN CP 50MG TABLET as advised by your physician. Swallow it with a
glass of water, and do not chew or crush it. Your doctor will decide the correct
dose and duration of CALURAN CP 50MG TABLET management for you depending upon
your age, body weight, and disease condition. Do not stop taking CALURAN CP 50MG
TABLET unless your doctor advises you to stop.

Side Effects Of CALURAN CP 50MG TABLET

Common

• skin rash, dry skin, itching
• swollen and tender breast tissue
• feeling weak, tired, and pale due to anemia (a decrease in red blood cells).
• reduced appetite, sex drive, and fertility
• depression
• dizziness, sleepiness
• hot flushes, constipation, indigestion, wind, nausea
• hair loss or increased hair growth on the body
• impotence
• chest pain, heart attack, reduced heart function
• swelling
• weight gain

Rare

• increased skin sensitivity to sunlight

Stop taking CALURAN CP 50MG TABLET and contact your doctor if you experience any
of the following side effects:

• signs of allergic reactions (rash, itching, or hives on the skin; swelling of the face, lips, tongue, throat, or other parts of the body; shortness of breath; wheezing or trouble breathing)
• signs of liver disease (yellowing of the skin or whites of your eyes, also called jaundice)
• stomach pain
• blood in your urine
• signs of interstitial lung disease (serious shortness of breath with or without a cough or fever)
• changes in ECG (QT prolongation)

How To Manage Side Effects

!### Constipation

Try to eat more high-fiber foods such as fresh fruit, vegetables, and cereals,
drink plenty of water, and exercise regularly. If this does not help, inform
your doctor about receiving alternate managements for constipation.

!### Dizziness Or Drowsiness

When you feel dizzy, lie down, or sit down immediately. Lie down in a dark and
quiet place with your eyes closed. Vehicle driving should be avoided if you
experience frequent dizziness without warning. If the symptom persists, contact
your doctor.

!### Nausea And Vomiting

Try to take CALURAN CP 50MG TABLET with or just after a meal or a snack. Stick
to simple meals. Avoid eating oily or spicy food. Drink ice-cold drinks. Try to
avoid sugary snacks and drinks. Avoid drinking too much liquid along with your
meals, drink slowly in between meals. If the symptom persists, contact your
doctor.

Warning & Precautions

!### Pregnancy

ContraindicatedCALURAN CP 50MG TABLET is not recommended for use by pregnant women. Patients
and their partners should use birth control while taking CALURAN CP 50MG TABLET
and for 130 days after stopping the> management. Consult your doctor before
taking it.

!### Breastfeeding

ContraindicatedCALURAN CP 50MG TABLET is not recommended for use by breastfeeding women.
Consult your doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel sleepy after taking CALURAN CP
50MG TABLET.

!### Alcohol

Consult your doctorAvoid consum

!### Kidney

ContraindicatedNo dosage adjustment of CALURAN CP 50MG TABLET is necessary for patients with
kidney impairment. Consult your doctor before taking it.

!### Liver

Use with CautionCALURAN CP 50MG TABLET should be used with caution in patients with liver
problems. Consult your doctor before taking it.

!### Allergy

Consult your doctorDo not take CALURAN CP 50MG TABLET if you are allergic to Bicalutamide or any of
the other ingredients of this medicine.

!### Heart Disease

Consult your doctorCALURAN CP 50MG TABLET should be used with caution in patients having any heart
or blood vessel conditions, including heart rhythm problems (arrhythmia), or who
are being managed with medicines for these conditions. Consult your doctor
before taking it.

!### Use In Pediatrics

ContraindicatedCALURAN CP 50MG TABLET is not recommended for use in children and adolescents
(below 18 years of age). Consult your child’s doctor for advice.

!### Use In Geriatrics

Consult your doctorCALURAN CP 50MG TABLET can be used in elderly patients (aged 70 years or older)
only if the life expectancy exceeds 10 years. Consult your doctor before taking
it.

Others

CALURAN CP 50MG TABLET is not recommended for use if you:

• are a woman

Before taking CALURAN CP 50MG TABLET, inform your doctor if you:

• have diabetes

Interactions

A. Drug- Drug Interactions:

Before taking CALURAN CP 50MG TABLET, inform your doctor if you are taking any
of the following medicines:

• cisapride (used for stomach disorders)
• terfenadine, astemizole (medicines used for hay fever or allergies)
• medicines used to manage heart rhythm problems (Ex. quinidine, procainamide, amiodarone, and sotalol)
• methadone (medicine used for pain relief and drug addiction detoxification)
• moxifloxacin (an antibiotic used in infections)
• medicines used for serious mental illnesses (Ex. clozapine, cariprazine)
• medicines used to manage blood clots (Ex. warfarin, heparin)
• ciclosporin (medicine used to suppress your immune system to manage rejection of a transplanted organ or bone marrow)
• certain medicines used to manage high blood pressure or other heart conditions (Ex. amlodipine, nifedipine)
• cimetidine (used to manage stomach ulcers)
• ketoconazole (used to manage fungal infections of the skin and nails)
• medicines used in certain cancer managements (Ex. buserelin, leuprorelin, and triptorelin)

Overdosage:

If you or anyone else accidentally takes too much of CALURAN CP 50MG TABLET,
contact your doctor immediately or go to a hospital right away.

Synopsis

Drug	:	Bicalutamide
Pharmacological Category	:	Non-Steriodal anti androgens
Therapeutic Indication	:	Metastatic Prostrate Cancer
Dosage Forms	:	Tablet

More Information

• Keep CALURAN CP 50MG TABLET out of reach of children
• Store CALURAN CP 50MG TABLET between 20-25°C

FAQs About CALURAN CP 50MG TABLET

Q: Can CALURAN CP 50MG TABLET affect male fertility?

A: Yes. CALURAN CP 50MG TABLET may influence male fertility, which could be
reversible. Patients and their partners should use birth control while taking
CALURAN CP 50MG TABLET and for 130 days after stopping the management. Consult
your doctor for further queries.

Q: What if I miss a dose of CALURAN CP 50MG TABLET?

A: If you miss a dose of CALURAN CP 50MG TABLET, take it as soon as you
remember. However, skip that dose if it's almost time for the next one. Do not
take CALURAN CP 50MG TABLET two times to make up for the missed dose.

Q: Can I go out in the sun while taking CALURAN CP 50MG TABLET?

A: Avoid direct exposure to excessive sunlight or UV light while you are taking
CALURAN CP 50MG TABLET, as it can increase your skin’s sensitivity to sunlight.
Discuss with your doctor how you can protect your skin from the sun during
management with CALURAN CP 50MG TABLET.

Q: Can CALURAN CP 50MG TABLET be taken during pregnancy?

A: CALURAN CP 50MG TABLET is strictly for use in men and is not recommended for
use in women, including pregnant women. If you are pregnant, think you may be
pregnant, or are planning to have a child, consult your doctor before taking it.

Q: Can CALURAN CP 50MG TABLET be taken by a diabetes patient?

A: CALURAN CP 50MG TABLETshould be used with caution in patients with diabetes
(high blood sugar levels). Consult your doctor before taking it. Your doctor may
advise you to check your blood sugar level before and during CALURAN CP 50MG
TABLET management.

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