MESTROLYST 40 Tablet 10's

Introduction About MESTROLYST 40 TABLET

MESTROLYST 40 TABLET contains Megestrol which belongs to the group of medicines
called Progestogens. MESTROLYST 40 TABLET is used for hormone dependent cancer
which includes breast and endometrial cancer in affected individuals. MESTROLYST
40 TABLET is also used for reduced appetite and weight-loss in patients passing
through an advanced stage of cancer/HIV. MESTROLYST 40 TABLET is not recommended
for use in patients allergic to Megestrol.

Before taking MESTROLYST 40 TABLET, inform your doctor if you have diabetes,
thrombophlebitis (blood clot due to inflammatory process), intolerance to
certain sugars (such as lactose), kidney problems (such as chronic kidney
disease), and/or severe liver problems. MESTROLYST 40 TABLET is not recommended
for use during pregnancy and in women planning for pregnancy. It is also not
recommended for use in breastfeeding women. MESTROLYST 40 TABLET is not
generally recommended for use in children and adolescents (aged below 18 years)
and is advised to be used with caution in elderly patients (aged 65 years and
above) after consulting the doctor.

The most common side effects of taking MESTROLYST 40 TABLET are increase in
appetite, shortness of breath, high blood pressure, hot flushes, nausea,
vomiting, passing wind, and/or constipation. Consult your doctor if any of these
side effects worsens.

Uses Of MESTROLYST 40 TABLET

It is used:

• For hormone dependent cancer which includes breast and endometrial cancer
• For reduced appetite and weight-loss in patients passing through an advanced stage of cancer or HIV

How MESTROLYST 40 TABLET Works

MESTROLYST 40 TABLET works by changing the hormone balance in the body which
results in interference of growth in hormone dependent cancer cells which leads
to inhibition of growth and spread of cancer cells.

How to use MESTROLYST 40 TABLET

Take MESTROLYST 40 TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

Side Effects Of MESTROLYST 40 TABLET

Common

• Increase in appetite
• Weight gain
• Shortness of breath
• High blood pressure
• Hot flushes, reddening of the face/neck, round face (moon face)
• Increased blood sugar
• Tiredness, feeling weak, nausea, vomiting, passing wind, constipation, diarrhea
• Swelling of a vein (due to blood clot)
• Changes in mood, numbness, pain, and/or tingling sensation in fingers/thumb
• Hair loss
• Impotence
• Needing to urinate often
• Changes in vaginal bleeding (breakthrough bleeding/spotting)
• Buildup of fluid which causes swelling (especially in ankles)
• Pain, rash, red itchy welts

Stop taking MESTROLYST 40 TABLET and contact your doctor immediately if you
experience any of the following side effects:

• Signs of blood clot such as loss of coordination, slurred speech, pain in groin, pain/ numbness in arm/leg, shortness of breath, weakness, headache, and/or fainting
• Signs of allergic reaction such as swelling of face/lips/tongue, skin rash, and/or difficulty in breathing

How To Manage Side Effects

!### Constipation

Eat fiber rich foods such as fresh fruits, vegetables, cereals and drink enough
water. Exercise more regularly. Consult your doctor if the symptom does not
improve.

!### Diarrhea

Drink lot of fluids such as water/fruit juice to keep yourself hydrated. Do not
take any medicine on your own for managing diarrhea. Consult your doctor if the
symptom does not improve.

!### Nausea And Vomiting

Stick to simple meals and avoid eating oily or spicy food. Do not perform any
strenuous activity immediately after eating. If the symptom does not improve,
contact your doctor.

!### Tiredness

Drink plenty of fluids and eat balanced diet and frequent meals. Do regular
minimal exercise and follow regular sleep schedule. If the symptom does not
improve, contact your doctor.

Warning & Precautions

!### Pregnancy

ContraindicatedMESTROLYST 40 TABLET is generally not recommended for use during pregnancy and
in women planning for pregnancy. Consult your doctor before taking the medicine.

!### Breastfeeding

ContraindicatedMESTROLYST 40 TABLET is not generally recommended for use in breastfeeding
women. Consult your doctor before taking the medicine.

!### Driving and Using Machines

Use with CautionMESTROLYST 40 TABLET is unlikely to affect your ability to drive/operate
machines. Consult your doctor before taking MESTROLYST 40 TABLET.

!### Kidney

Use with CautionMESTROLYST 40 TABLET should be used with caution in patients with kidney
problems such as chronic kidney disease. Consult your doctor before taking
MESTROLYST 40 TABLET.

!### Liver

Use with CautionMESTROLYST 40 TABLET should be used with caution in patients with severe liver
problems. Consult your doctor before taking MESTROLYST 40 TABLET.

!### Allergy

ContraindicatedDo not take MESTROLYST 40 TABLET if you are allergic to Megestrol, and/or any
other ingredients of this medicine.

!### Use In Pediatrics

ContraindicatedMESTROLYST 40 TABLET is not recommended for use in children and adolescents
(aged below 18 years). Consult your doctor for advice.

!### Use In Geriatrics

Use with CautionMESTROLYST 40 TABLET should be used with caution in elderly patients (aged 65
years/above). Consult your doctor before taking MESTROLYST 40 TABLET.

Others

Before taking MESTROLYST 40 TABLET, inform your doctor if you:

• Have diabetes
• Are currently suffer/have a history of thrombophlebitis (blood clot due to inflammatory process)
• Are intolerance to certain sugars such as lactose

Interactions

A. Drug-Drug interactions:

Inform your doctor if you are taking any medicines including prescri
non-prescri
supplements before taking this medicine.

Overdosage:

If you or anyone else accidentally take too much of MESTROLYST 40 TABLET,
consult your doctor immediately or visit the nearby hospital to manage overdose
symptoms.

Synopsis

Drug	:	Megestrol
Pharmacological Category	:	Progestin
Therapeutic Indication	:	Hormone-dependent cancers (Breast cancer, Endometrial Cancer),Reduces appetite and weight-loss in patients (in advanced stage of cancer/HIV)
Dosage Forms	:	Tablet

More Information

Storage

• Keep MESTROLYST 40 TABLET out of reach of children
• Do not store MESTROLYST 40 TABLET above 25°C

FAQs About MESTROLYST 40 TABLET

Q: What is MESTROLYST 40 TABLET used for?

A: MESTROLYST 40 TABLET is used for hormone dependent cancer which includes
breast and endometrial cancer in affected individuals. It is also used for
reduced appetite and weight-loss in patients passing through an advanced stage
of cancer/HIV.

Q: What are the side effects of MESTROLYST 40 TABLET?

A: The most common side effects of taking MESTROLYST 40 TABLET are increase in
appetite, shortness of breath, high blood pressure, hot flushes, nausea,
vomiting, passing wind, and/or constipation. Consult your doctor if any of these
side effects worsens.

Q: Can MESTROLYST 40 TABLET be used in pregnant and breastfeeding women?

A: No, MESTROLYST 40 TABLET is not recommended for use during pregnancy and in
women planning for pregnancy. It is also not recommended for use in
breastfeeding women. Consult your doctor before taking the medicine.

Q: How MESTROLYST 40 TABLET works?

A: MESTROLYST 40 TABLET works by changing the hormone balance in the body which
results in interference of growth in hormone dependent cancer cells which leads
to inhibition of growth and spread of cancer cells.

Q: What happens if MESTROLYST 40 TABLET is taken more than its required dosage?

A: If you or anyone else accidentally take too much of MESTROLYST 40 TABLET,
consult your doctor immediately or visit the nearby hospital to manage overdose
symptoms.

Useful Diagnostic Tests

• Blood tests
• Computerized tomography (CT) scan
• Positron emission tomography (PET) scan