Xenosoul Tablet 5'S

Introduction About XENOSOUL TABLET

XENOSOUL TABLET contains Anastrozole, which belongs to the group of medicines
called Anti-cancer drugs. It works by lowering the levels of a female sex
hormone called oestrogen (responsible for the growth and proliferation of tumour
cells in the breast) in women who have undergone menopause.

Along with the management, you might have to undergo some lifestyle changes,
such as maintaining a healthy weight, exercising, and quitting alcohol. Prior to
the management of XENOSOUL TABLET, your doctor might want you to take some
diagnostic tests to better evaluate your condition.

Before taking XENOSOUL TABLET, inform your doctor if you have liver or kidney
problems, lactose intolerance, or osteoporosis (decreased strength of bones).

If you are pregnant or breastfeeding, you should not take XENOSOUL TABLET
without the consultation of your doctor.

XENOSOUL TABLET is not recommended for use in children and adolescents. It
should be used with caution with elderly patients.

The most common side effects of taking XENOSOUL TABLET are hot flushes,
weakness, pain, stiffness or inflammation in joints, nausea, vomiting, and loss
of appetite. Consult your doctor if any of the side effects worsen.

Uses Of XENOSOUL TABLET

• To lower the levels of oestrogen in post-menopausal women

How XENOSOUL TABLET Works

XENOSOUL TABLET works by lowering the levels of a sex hormone called oestrogen
in liver, fat, muscle, and breast cells by inhibiting the aromatase enzyme,
which converts androgens into oestrogen (which stimulates the growth and
proliferation of tumour cells in the breast).

How to use XENOSOUL TABLET

Take XENOSOUL TABLET as advised by your physician. Swallow the medicine with a
glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration for you depending on your age, body weight, and
disease condition.

Side Effects Of XENOSOUL TABLET

Common

• hot flushes
• feeling weak and sleepy
• pain or stiffness in your joints
• inflammation of the joints (arthritis)
• allergic reactions, including face, lips, tongue, or skin rash (hypersensitivity)
• nausea and vomiting
• headache
• bone loss (osteoporosis)
• vaginal dryness, bleeding from the vagina
• thinning of your hair (hair loss)
• diarrhoea
• loss of appetite
• tingling, pain, coldness, and weakness in parts of the hand (carpel tunnel syndrome)
• tickling, tingling, or numbness of the skin
• loss or lack of taste
• muscle pain

Uncommon

• a condition in which your finger or thumb gets stuck in a bent position (trigger finger)
• inflammation of the liver (hepatitis)
• hives or nettle rash (red, itchy, raised bumps on the skin)

Rare

• inflammation of the small blood vessels causing red or purple colouring of the skin

Stop taking XENOSOUL TABLET and contact your doctor immediately if you
experience any of the following side effects:

• severe skin reaction with ulcers or blisters on the skin (Stevens-Johnson syndrome)
• allergic (hypersensitivity) reactions with swelling of the throat that may cause difficulty swallowing or breathing (angioedema)

How To Manage Side Effects

!### Diarrhea

Drink a lot of fluids, such as water or fruit juice, to keep yourself hydrated.
Do not consume any medicine on your own for managing diarrhea without consulting
your doctor. Consult your doctor if the symptoms do not improve.

Headache

Drink an ample amount of water. Get adequate rest. Try to be relaxed and
stress-free. Apply a pain-relieving balm to your forehead if necessary. Consult
your doctor if the symptom does not improve.

!### Loss Of Appetite

Eat when you feel hungry. Eat smaller meals more frequently than usual. Snack
only when you're hungry. Eat a nutritious snack that is rich in calories and
protein, such as dried fruit and nuts. Consult your doctor if the symptoms do
not improve.

!### Muscle Cramps

Try to rest and relax. Keep a heat pad on the affected area. If the symptom does
not improve, contact your doctor.

!### Nausea And Vomiting

Take this medicine with or just after meals. Stick to simple meals. Avoid eating
oily or spicy foods. Consult your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

ContraindicatedXENOSOUL TABLET is not recommended for use by pregnant women. Consult your
doctor before taking it.

!### Breastfeeding

ContraindicatedXENOSOUL TABLET is not recommended for use by breastfeeding women. Consult your
doctor before taking it.

!### Driving and Using Machines

Consult your doctorDo not drive or operate any machines if you feel weak or sleepy after taking
XENOSOUL TABLET.

!### Kidney

Use with CautionXENOSOUL TABLET should be taken with caution in patients with kidney problems.
Consult your doctor before taking it.

!### Liver

Use with CautionXENOSOUL TABLET should be taken with caution in patients with liver problems.
Consult your doctor before taking it.

!### Allergy

Use with CautionDo not take XENOSOUL TABLET if you are allergic to Anastrozole or any other
ingredients of this medicine.

!### Use In Pediatrics

ContraindicatedXENOSOUL TABLET is not recommended for use in children and adolescents. Consult
your child’s doctor for advice.

!### Use In Geriatrics

Use with CautionXENOSOUL TABLET should be used with caution with elderly patients. Consult your
doctor before taking it.

Others

Before taking XENOSOUL TABLET, inform your doctor if you:

• have menstrual periods
• have osteoporosis or any condition that affects the strength of the bones
• have lactose intolerance

Interactions

A. Drug-drug interactions:

• selective estrogen receptor modulators (used to manage breast cancer) Ex. tamoxifen
• medicines that contain estrogen (used in hormone replacement therapy)
• LHRH analogue (used to manage breast cancer, gynaecological conditions, and infertility) Ex. gonadorelin, buserelin, goserelin, leuprorelin, and triptorelin
• herbal medicines

Overdosage:

If you or anyone else accidentally takes too much of XENOSOUL TABLET, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Anastrozole
Pharmacological Category	:	Aromatase Inhibitors
Therapeutic Indication	:	To lower the levels of oestrogen in post-menopausal women
Dosage Forms	:	Tablet, Capsule

More Information

• Keep XENOSOUL TABLET out of reach of children
• Store away from moisture, at a temperature not above 30°C

FAQs About XENOSOUL TABLET

Q: Does XENOSOUL TABLET affect bone health?

A: Yes, XENOSOUL TABLET acts by lowering the estrogen levels in the body, which
is an important hormone to maintain bone health. Due to this, the mineral
content of the bones decreases, and they may become less strong and more prone
to fracture. Your doctor might ask you to take several tests to better assess
and manage your condition.

Q: Can I stop taking XENOSOUL TABLET on my own?

A: No, do not stop taking XENOSOUL TABLET without the advice of your doctor.
However, not taking the medicine at the recommended time may increase the risk
of your breast cancer recurring.

Q: Is XENOSOUL TABLET a form of chemotherapy?

A: No, XENOSOUL TABLET acts by decreasing the estrogen levels in the body, which
is a hormone. This in turn decreases the growth of cancer cells in breasts.
XENOSOUL TABLET is hormone therapy.

Q: Who should avoid taking XENOSOUL TABLET?

A: XENOSOUL TABLET is not recommended if you still have menstrual periods, are
pregnant or planning to become pregnant, or are allergic to XENOSOUL TABLET.
Consult your doctor before taking XENOSOUL TABLET.

Q: What if I forget to take a dose of XENOSOUL TABLET?

A: If you forget to take a dose of XENOSOUL TABLET, just take your next dose as
normal. Do not take two doses of XENOSOUL TABLET at the same time to make up for
a forgotten dose.

Q: Can alcohol be consumed with XENOSOUL TABLET?

A: It is best to avoid or limit alcohol intake when XENOSOUL TABLET is taken,
since alcohol can raise your risk of experiencing side effects from XENOSOUL
TABLET such as hot flashes or joint pain.

Q: Should calcium be taken with XENOSOUL TABLET?

A: It is advisable to take calcium and vitamin D supplements while XENOSOUL
TABLET is taken since the medicine may cause bone loss as a side effect, which
can be monitored by a bone mineral density (BMD) test if done every 1 to 2
years.

Q: Is XENOSOUL TABLET safe to use with children?

A: XENOSOUL TABLET is not recommended for use in children and adolescents under
18 years of age due to a lack of safety and effectiveness. Generally, breast
cancer occurs in older women. However, consult your doctor for advice before
taking XENOSOUL TABLET.

Useful Diagnostic Tests

• Biopsy
• Mammogram
• Estrogen receptor (ER)
• Progesterone receptor (PR)
• Bone density test