XEPRICH 10mg Capsule 10's

Introduction About XEPRICH 10MG CAPSULE

XEPRICH 10MG CAPSULE contains Doxepin which belongs to the group of medicines
called Tricyclic Antidepressants. It is used to manage depression (mood disorder
with the symptoms of sadness, loss of interest and suicidal thoughts) and
difficulty in sleeping because of depression.

Avoid consum
drowsiness. XEPRICH 10MG CAPSULE is not suitable for use in patients with severe
liver disease, who suffer from a type of mood disorder called m
elevated mood state), have glaucoma (increased eye pressure), or have difficulty
in passing urine.

Before taking XEPRICH 10MG CAPSULE inform your doctor if you have suicidal
thoughts or have attempted suicide in the past, have kidney, heart problems or
had a heart attack recently, intolerant to certain sugars, have epilepsy (fits),
are going to have an operation or dental surgery. If you have thoughts of
harming or killing yourself (increased when first starting antidepressants,
since these medicines take time to work) inform your doctor immediately.

XEPRICH 10MG CAPSULE is not recommended for use in pregnant or breast-feeding
women, consult your doctor for advice. It is not recommended for use in children
and adolescents under 18 years of age and caution to be exercised in elderly
patients. The most common side effects of taking XEPRICH 10MG CAPSULE are
drowsiness, dry mouth and constipation Consult your doctor if the symptom
worsens.

Uses Of XEPRICH 10MG CAPSULE

• it is used to manage depression associated with symptoms of feeling sad, tearful, unable to enjoy life, or difficulty in sleeping

How XEPRICH 10MG CAPSULE Works

XEPRICH 10MG CAPSULE works by increasing the concentration of the
neurotransmitter called serotonin (a chemical that acts as a messenger between
nerve cells of brain and throughout the body) and norepinephrine (a
neurotransmitter that plays an important role in body’s fight-flight response)
in the brain as these substances are found to be low in the depressed and
anxiety patients.

How to use XEPRICH 10MG CAPSULE

Take XEPRICH 10MG CAPSULE as advised by your physician.

For Tablet, Capsule: Swallow XEPRICH 10MG CAPSULE with a glass of water. Do
not crush or chew the medicine.

For Dispersible Tablet: Disperse XEPRICH 10MG CAPSULE in the specified
quantity of water as mentioned on the label. Consume the mixture immediately
after reconstitution.

Take this medicine while standing or sitting upright. Your doctor will decide
the correct dose and duration of therapy for you depending upon your age, body
weight and disease condition.

Side Effects Of XEPRICH 10MG CAPSULE

Common

• drowsiness
• dry mouth
• constipation

Uncommon

• skin rash
• itching
• face swelling
• pink, itchy swellings on the skin, hives
• increased sensitivity of the skin to sun

Rare

• difficulty in passing urine
• breast enlargement in both men and women, breast milk production when not pregnant or breastfeeding
• irregular heartbeat
• jaundice (yellow eyes or skin)
• seizures (fits)
• hallucinations (Seeing, feeling, or hearing things that are not there)
• ataxia (problems with coordination, balance, and speech)
• signs of blood disorders such as fever or chills and painful ulceration in the mouth or rectum, unusual bruising or bleeding, anemia
• ringing or buzzing in the ears
• urinating less than normal (excessive production of antidiuretic hormone)

Stop taking XEPRICH 10MG CAPSULE and contact your doctor immediately if you
experience any of the following side effects:

• thoughts of suicide, harming or killing yourself or worsening of depression or anxiety
• bone fractures

How To Manage Side Effects

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and
drink plenty of water. Exercise more regularly. Consult your doctor if symptoms
don't improve.

Drowsiness:

When you feel drowsy, lie, or sit down immediately. If you're experiencing a
severe episode of vertigo, lie in a dark and quiet place with eyes closed.
Vehicle driving should be avoided if you experience frequent drowsiness without
warning. Talk to your doctor if the symptoms worsen.

Dry mouth:

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard
candies to stimulate the flow of saliva. Sip water at regular intervals of time.
Do not use mouthwashes that contain alcohol because they can be drying. Consult
your doctor if symptoms don't improve.

Warning & Precautions

!### Pregnancy

XEPRICH 10MG CAPSULE is not recommended for use in pregnancy or women planning
to have a baby. Consult your doctor before taking XEPRICH 10MG CAPSULE.

!### Breastfeeding

XEPRICH 10MG CAPSULE is not recommended for use in breastfeeding women. Consult
your doctor for advice before taking it.

!### Driving and Using Machines

Do not drive or operate any machines if you feel sleepy after taking this
medicine. Consult your doctor before taking XEPRICH 10MG CAPSULE.

!### Alcohol

Avoid consum
drowsiness.

!### Kidney

XEPRICH 10MG CAPSULE should be taken with caution in patients with kidney
problems. Dose will be adjusted by your doctor. Consult your doctor before
taking it.

!### Liver

XEPRICH 10MG CAPSULE is not recommended for use in patients with severe liver
problems. Consult your doctor before taking it.

!### Allergy

XEPRICH 10MG CAPSULE is not recommended for use if you are allergic to Doxepin
or any other ingredients of this medicine.

!### Heart Disease

XEPRICH 10MG CAPSULE should be taken with caution in patients who had a heart
attack recently or have any other heart problems. Before taking XEPRICH 10MG
CAPSULE consult with your doctor.

Others

XEPRICH 10MG CAPSULE is not recommended for use if you have:

• mood disorder called m
• glaucoma (increased eye pressure)
• difficulty in passing urine

Before taking XEPRICH 10MG CAPSULE, inform your doctor if you have:

• suicidal thoughts or have attempted suicide in the past
• fits (epilepsy)
• intolerant to certain sugar
• are going to have a surgical operation or dental surgery

Use in pediatrics:

XEPRICH 10MG CAPSULE is not recommended for use in children and adolescents
below 18 years of age. Consult your doctor before taking XEPRICH 10MG CAPSULE.

Use in geriatrics:

XEPRICH 10MG CAPSULE is used with caution in elderly patients. Dose will be
adjusted by your doctor. Before taking XEPRICH 10MG CAPSULE, consult your
doctor.

Interactions

A. Drug - Drug interactions:

Before taking XEPRICH 10MG CAPSULE, inform your doctor if you are taking any of
the following medicines:

• monoamine oxidase inhibitors like isocarboxazid, phenelzine (medicines used to manage depression)
• barbiturates like phenobarbital, pentobarbital (medicines used to manage insomnia) or other sleeping medicines like triazolam, zolpidem
• medicines like telmisartan, losartan. captopril used to lower blood pressure
• sympathomimetics, such as nasal decongestants (Ex. oxymetazoline, phenylephrine, pseudoephedrine) and bronchodilators (Ex. salmeterol, albuterol) both are used for cold and hay fever
• medicines like fluticasone, beclomethasone used to manage asthma
• cimetidine (medicine used to manage ulcers and other stomach complaints)
• thyroid hormones like thyroxine (medicine used to manage thyroid disorders)
• chlorpromazine (medicine used to manage mental illness)
• sublingual nitrates like nitro-glycerine (used to manage angina and heart failure)
• buprenorphine/opioids (medicine used to manage opioid overdose)

Overdosage:

If you or anyone else accidentally takes too much of XEPRICH 10MG CAPSULE,
consult your doctor immediately or visit the nearby hospital. Signs and symptoms
of overdose include drowsiness, stupor (nearly unconscious), blurred vision and
excessive dryness of the mouth. Severe overdose may cause loss of consciousness,
reduced breathing rate, convulsions (fits), low blood pressure, unusually fast
heartbeat, or palpitations.

Synopsis

Drug	:	Doxepin
Pharmacological Category	:	Tricyclic Antidepressants
Therapeutic Indication	:	Depression and difficulty sleeping
Dosage Forms	:	Tablet, Capsule, Cream, Dispersible Tablet

More Information

• Keep XEPRICH 10MG CAPSULE out of reach of children
• Store at room temperature

FAQs About XEPRICH 10MG CAPSULE

How does XEPRICH 10MG CAPSULE work?

XEPRICH 10MG CAPSULE works by increasing the concentration of the
neurotransmitter called serotonin (a chemical that acts as a messenger between
nerve cells of brain and throughout the body) and norepinephrine (a
neurotransmitter that plays an important role in body’s fight-flight response)
in the brain as these substances are found to be low in the depressed and
anxiety patients.

What is XEPRICH 10MG CAPSULE used for?

XEPRICH 10MG CAPSULE is used to manage depression (mood disorder with the
symptoms of sadness, loss of interest and suicidal thoughts) and difficulty in
sleeping because of depression.

Does XEPRICH 10MG CAPSULE cause drowsiness?

Yes, this medicine may cause drowsiness in some people. When you feel drowsy,
lie, or sit down immediately. If you're experiencing a severe episode of
vertigo, lie in a dark and quiet place with eyes closed. Talk to your doctor if
the symptoms worsen.

Can XEPRICH 10MG CAPSULE be taken with Zolpidem?

No, taking XEPRICH 10MG CAPSULE along with Zolpidem may increase side effects
such as dizziness, drowsiness, confusion, and difficulty concentrating. Consult
your doctor before taking this medicine.

Is XEPRICH 10MG CAPSULE addictive?

No, XEPRICH 10MG CAPSULE is one of the few medicines used to manage insomnia
that doesn’t cause addiction or dependency. Consult your doctor for more
information on safety measures.