AMITRYN 50 Tablet 10's

Introduction About AMITRYN 50 TABLET

AMITRYN 50 TABLET is used in the management of depression, neuropathic pain and
tension type headache or migraine in adults. It contains a medicine
called Amitriptyline which is an antidepressant medicine. It enhances your mood
by boosting the levels of a chemical called serotonin in your brain.

AMITRYN 50 TABLET must be used under medical supervision. Take this medicine for
the duration exactly as advised by your doctor. Do not stop therapy abruptly or
overuse this medicine for prolonged periods without consulting your doctor.
Regularly visit your doctor and perform the medical tests suggested by your
doctor to achieve better results.

Avoid concomitant usage of AMITRYN 50 TABLET with other antidepressants like
MAOIs to avoid potential drug-drug interactions. Do not take if you have taken
any MAOIs within the last 14 days without consulting your doctor. It should not
be used in patients with severe liver problems, recent heart attack, or heart
problems.

Before taking AMITRYN 50 TABLET, inform your doctor if you have imbalances of
potassium and magnesium levels in the body and other mental illness like bipolar
disorder and schizophrenia. You must also inform your doctor if you are
scheduled for any surgery in the upcoming days, have diabetes, thyroid
disorders, epilepsy, narrow angle glaucoma, enlarged prostate and blockage or
stenosis in the gut as a precaution.

AMITRYN 50 TABLET should be used during pregnancy and breastfeeding only if it
is considered clearly necessary by the physician.

The most common side effects of taking AMITRYN 50 TABLET are excessive
sleepiness/drowsiness, dizziness, headache, tiredness, dry mouth, constipation,
excessive thirst, excessive sweating, weight gain, changes in taste, confusion,
lack of attention, unable to walk properly, low sex-drive, problems with
erection, tingling and numbness of arms or legs and problems in urination.
Consult your doctor if they trouble you.

Also, patients or caregivers must close monitor the patients and inform the
doctor immediately if the patients develop suicidal thoughts, m
changes after taking AMITRYN 50 TABLET.

Uses Of AMITRYN 50 TABLET

• Management of depression, neuropathic pain and tension type headache or migraine in adults

How AMITRYN 50 TABLET Works

AMITRYN 50 TABLET is a tricyclic antidepressant. It works by increasing the
levels of certain neurotransmitters in the brain, primarily serotonin and
norepinephrine by inhibiting their reuptake into nerve cells, which helps to
improve mood and relieve symptoms of depression.

How to use AMITRYN 50 TABLET

• Take AMITRYN 50 TABLET as advised by your physician.
• Swallow the medicine with a glass of water.
• Do not crush or chew the medicine.
• Do not stop taking AMITRYN 50 TABLET without consulting your doctor.
• Your doctor will decide the correct dosage and duration of therapy based on your age, body weight and health condition.

Side Effects Of AMITRYN 50 TABLET

Like all medicines, AMITRYN 50 TABLET may cause few side effects although not
everybody gets them

Common side effects of AMITRYN 50 TABLET:

• sleepiness/drowsiness
• shivering or shakiness of hands or other body parts
• dizziness, headache, tiredness
• irregular heartbeat
• dizziness while standing up or changing posture
• dry mouth, constipation, nausea, excessive thirst
• excessive sweating
• weight gain, changes in taste,
• slurred or slow speech
• vision problems, nasal congestion, dilated pupils
• confusion, lack of attention, unable to walk properly
• sexual disturbances (low sex-drive, problems with erection)
• tingling and numbness of arms or legs
• problems in urination

Stop taking AMITRYN 50 TABLET and consult your doctor immediately if you
experience any of the following side effects:

• suicidal thoughts (thoughts of harming or killing themselves), anxiety
• m

Warning & Precautions

!### Pregnancy

Monitoring requiredAMITRYN 50 TABLET should be used during pregnancy only if it is considered
clearly necessary by the physician. Your doctor will prescribe this medicine
only if it benefits the mother and justifies the risk to the fetus.

!### Breastfeeding

Consult your doctorAMITRYN 50 TABLET may pass through breast milk. Therefore, a decision should be
made whether to discontinue nursing or to discontinue the drug, taking into
account the importance of the drug to the mother.

!### Driving and Using Machines

Use with CautionAMITRYN 50 TABLET may cause dizziness and drowsiness. Therefore, do not drive or
handle any heavy tools or machineries until your concentration becomes clear
after taking this medicine.

!### Alcohol

Consult your doctorIt is advised to avoid alcohol consum
50 TABLET as it could increase your drowsiness.

!### Liver

ContraindicatedAMITRYN 50 TABLET is not recommended for use in patients with severe liver
disease.

!### Allergy

ContraindicatedDo not take AMITRYN 50 TABLET if you are allergic to Amitriptyline or any other
ingredients of this medicine.

!### Heart Disease

Consult your doctorAMITRYN 50 TABLET is not recommended for use in patients who suffered a recent
heart attack or have heart problems such as disturbances in heart rhythm, or
coronary artery disease. It should be used with caution in patients with heart
problems such as slow heart rate or difficulty in pumping blood, etc.

!### Use In Pediatrics

Consult your doctorAMITRYN 50 TABLET is generally not recommended for use in children and
adolescents (aged below 18 years). However, your doctor may prescribe it to you
after considering the risks and benefits.

!### Use In Geriatrics

Monitoring requiredAMITRYN 50 TABLET should be used with extreme caution in elderly patients as it
could increase of fall due to its tendency to cause dizziness and hypotension.
Therefore, caregivers should closely monitor the elderly patients.

Others

AMITRYN 50 TABLET is not recommended for use if you have:

• taken other antidepressants called MAOIs within the last 14 days
• moclobemide the day before

Before taking AMITRYN 50 TABLET, inform your doctor if you:

• have any underlying health condition that causes low potassium or magnesium levels in the body
• have a high level of potassium in your blood
• are scheduled for any surgery in the upcoming days
• have an overactive thyroid gland or take thyroid medication
• have bipolar disorder
• have narrow angle glaucoma
• have epilepsy or a previous history of fits
• have difficulty in passing urine
• have an enlarged prostate
• have disorders of thyroid gland
• have schizophrenia
• have pylorus stenosis (narrowing of the gastric outlet) and paralytic ileus (blocked intestine)
• have diabetes

Interactions

A. Drug-Drug interactions:

• Monoamine oxidase inhibitors (such as isocarboxazid, phenelzine, selegiline, and tranylcypromine, moclobemide)
• Cisapride (used for gastric ulcers)
• Selegiline (an antiparkinsonian drug)
• Sympathetic agents (such as adrenaline, ephedrine, isoprenaline, noradrenaline, phenylephrine and phenylpropanolamine present in cough or cold medicine)
• Antihypertensive medicines (such as diltiazem, verapamil, guanethidine, bet
• Anticholinergic drugs (such as atropine, hyoscyamine)
• Thioridazine (an antipsychotic agent for schizophrenia)
• Tramadol (a painkiller)
• Antifungal agents (such as fluconazole, terbinafine, ketoconazole, and itraconazole)
• Sedatives and hyponotics
• Other antidepressants (such as SSRIs (fluoxetine, paroxetine, fluvoxamine), duloxetine and bupropion)
• Buprenorphine/Opioids, methadone (pain killers)
• Cardiac drugs (such as beta blockers and antiarrhythmics)
• Cimetidine (used for stomach ulcers)
• Methylphenidate (used for ADHD)
• Ritonavir (an anti-HIV agent)
• Oral contrace
• Rifampicin (used for infections)
• Antiepile
• St. John´s Wort (hypericum perforatum) an herbal antidepressant
• Thyroid medication
• Anti-allergic medicines (such as astemizole and terfenadine)
• Medicines used for some mental illnesses (such as pimozide and sertindole)
• Halofantrine (an antimalarial agent)
• Diuretics (such as furosemide)

Overdosage:

If you or anyone else accidentally taken too much of AMITRYN 50 TABLET consult
your doctor immediately or visit the nearby hospital straight away. Symptoms of
overdosage might include dilated pupils, fast or irregular heartbeats,
difficulties in passing urine, dry mouth, fits, fever, agitation, confusion,
hallucinations, uncontrolled movements, weak pulse, pallor, blue discolouration
of the skin, slow heart rate, extreme drowsiness and abnormal heart rhythm.

Synopsis

Drug	:	Amitriptyline
Pharmacological Category	:	Tricyclic Antidepressants
Therapeutic Indication	:	Depression, Neuropathic pain, Headache
Dosage Forms	:	Tablet, Injection

More Information

Storage

• Keep AMITRYN 50 TABLET out of reach of children
• Store AMITRYN 50 TABLET at room temperature

FAQs About AMITRYN 50 TABLET

Q: What is AMITRYN 50 TABLET used for?

A: AMITRYN 50 TABLET is used in the management of depression, neuropathic pain
and tension type headache or migraine in adults. It contains a medicine called
Amitriptyline which is an antidepressant medicine. It enhances your mood by
boosting the levels of a chemical called serotonin in your brain.

Q: How AMITRYN 50 TABLET works?

A: AMITRYN 50 TABLET is a tricyclic antidepressant. It works by increasing the
levels of certain neurotransmitters in the brain, primarily serotonin and
norepinephrine by inhibiting their reuptake into nerve cells, which helps to
improve mood and relieve symptoms of depression.

Q: Can AMITRYN 50 TABLET be used in children?

A: AMITRYN 50 TABLET is generally not recommended for use in children and
adolescents (aged below 18 years). However, your doctor may prescribe it to you
after considering the risks and benefits. Therefore, consult your doctor for
advice.

Q: Can AMITRYN 50 TABLET be used during pregnancy?

A: AMITRYN 50 TABLET should be used during pregnancy only if it is considered
clearly necessary by the physician. Your doctor will prescribe this medicine
only if it benefits the mother and justifies the risk to the fetus. Therefore,
inform your doctor if you are pregnant, think you may be pregnant or planning
for a baby before starting therapy with this medicine.

Q: Can AMITRYN 50 TABLET cause weight gain?

A: Amitriptyline can cause weight gain as a side effect. This is relatively
common with tricyclic antidepressants, including amitriptyline. The weight gain
may be due to increased appetite, changes in metabolism, or fluid retention. If
you are concerned about weight gain while taking amitriptyline, it is important
to discuss this with your healthcare provider. They can offer strategies to
manage weight, such as dietary changes, increased physical activity, or
potentially adjusting the medication regimen.

Q: Can AMITRYN 50 TABLET cause hair loss?

A: Amitriptyline is not commonly associated with hair loss, but it can occur as
a rare side effect. Hair loss, or alopecia, is listed as a potential side effect
of many medications, including some antidepressants. If you experience hair loss
while taking AMITRYN 50 TABLET, it is important to discuss this with your
healthcare provider. They can determine whether the medication is the likely
cause and discuss possible alternatives or treatments to manage this side
effect.

Q: Can AMITRYN 50 TABLET cause sexual problems?

A: AMITRYN 50 TABLET can cause sexual problems as a side effect. These issues
may include decreased libido, difficulty achieving orgasm, or erectile
dysfunction. These side effects are due to the drug's impact on
neurotransmitters, which can affect sexual function. If you experience sexual
problems while taking AMITRYN 50 TABLET, it is important to talk to your doctor.

Q: When will I start feeling better after taking AMITRYN 50 TABLET?

A: The time it takes to start feeling better after beginning amitriptyline can
vary. Typically, some people may start to notice improvements in their symptoms
within 1 to 2 weeks. However, it often takes 4 to 6 weeks to experience the full
therapeutic effects. It's important to continue taking the medication as
prescribed and to be patient, as antidepressants can take time to work. If you
have any concerns about your progress or side effects, consult your healthcare
provider for guidance.

Q: Can AMITRYN 50 TABLET cause problems in urination?

A: AMITRYN 50 TABLET can cause problems in urination. It may lead to urinary
retention, difficulty starting urination, or a decreased ability to empty the
bladder completely. These side effects occur because amitriptyline has
anticholinergic properties, which can affect the bladder muscles and the signals
that control urination. If you experience any urinary issues while taking
amitriptyline, it is important to discuss them with your doctor at the earliest.

Q: Can I consume alcohol while taking AMITRYN 50 TABLET?

A: It is generally advised to avoid consuming alcohol while taking
amitriptyline. Alcohol can increase the sedative effects of amitriptyline,
leading to enhanced drowsiness, dizziness, and difficulty concentrating.

Q: What precautions must be followed while taking AMITRYN 50 TABLET?

A: GBNKEYWORD] must be used under medical supervision. Take this medicine for
the duration exactly as advised by your doctor. Do not stop therapy abruptly or
overuse this medicine for prolonged periods without consulting your doctor.
Regularly visit your doctor and perform the medical tests suggested by your
doctor to achieve better results. Avoid concomitant usage of AMITRYN 50 TABLET
with other antidepressants like MAOIs to avoid potential drug-drug interactions.
Before taking AMITRYN 50 TABLET, inform your doctor about your current and
previous medical history, presence of neurological and other mental disorders,
pregnancy and breastfeeding. Patients or caregivers must close monitor the
patients and inform the doctor immediately if the patients develop suicidal
thoughts, m

Useful Diagnostic Tests

• Healthy Midlife Checkup
• Full Body Checkup – Gold