TROYCURIUM INJECTION 2.5ML

Introduction About TROYCURIUM

TROYCURIUM contains Atracurium which belongs to the group of medicines called
Muscle relaxants. It relaxes your muscles and keeps your body still (immobile)
during a surgery. It also relaxes the airway muscles which help in artificial
breathing and in facilitating easy insertion of breathing tubes into the
airways.

Before receiving TROYCURIUM inform your doctor if you have any heart problems.
You must also inform your doctor if you have a history of asthma or allergic
conditions, any nerve or muscle disorders, electrolyte imbalance or if you are
severely dehydrated.

TROYCURIUM should be used in pregnant or breastfeeding women only if it is
considered necessary by the physician. However, it may be used during a
caesarean section in pregnant women under close supervision.

TROYCURIUM may cause difficulty in breathing which is due to relaxation of
muscle involved in breathing. In such cases, your doctor might provide you with
additional ventilation support until the effect of TROYCURIUM wears off.

Other most common side effects of receiving TROYCURIUM are pain or irritation at
the site of injection, slow of fast heart rate, low or high blood pressure and
flushing of skin. Inform your doctor if any of these symptoms worsen.

Uses Of TROYCURIUM

• Used during surgeries to relax muscles
• Helps in artificial breathing by relaxing airway muscles
• Facilitates easy insertion of breathing tubes into the airways

How TROYCURIUM Works

TROYCURIUM is a muscle relaxant. It works by blocking the transmission of nerve
signals from the nerve fibers to the muscles. As a result, it causes muscle
relaxation and help you stay immobile during surgeries. TROYCURIUM can also
relax the airway muscles which helps in easy insertion of breathing tubes into
the airways and in artificial breathing.

How to use TROYCURIUM

TROYCURIUM will be given to you only by a doctor or a nurse into the vein
(intravenously) under close monitoring. Your doctor will decide the correct dose
for you depending upon your age, body weight and health condition.

Side Effects Of TROYCURIUM

Common

• slow or very fast heartbeat
• changes in blood pressure (low or high)
• difficulty in breathing
• flushing
• pain, itching or irritation at the site of injection
• redness or itchy rashes of the skin

Rare

• bronchospasm (tightness of airway muscles)

Contact your doctor immediately if you experience any of the following side
effects after receiving TROYCURIUM:

• severe allergic reactions (such as skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue and/or throat with difficulty in breathing or swallowing)
• fits, cardiac arrest

How To Manage Side Effects

!### Injection Site Reactions

Place an ice pack on the injected site. Do not move the affected area
frequently. If the symptom worsens, consult your doctor.

Warning & Precautions

!### Pregnancy

Monitoring requiredTROYCURIUM should be used in pregnant women only if it is considered necessary
by the physician. Therefore, inform your doctor if you are pregnant or think you
may be pregnant before receiving TROYCURIUM. However, TROYCURIUM can be used
during a caesarean section in pregnant women under close medical supervision.

!### Breastfeeding

Monitoring requiredTROYCURIUM should be used in breastfeeding women only if it is considered
necessary by the physician. Therefore, inform your doctor before receiving it.
The nursing infant should be monitored closely when the mother receives this
medicine.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines until the effects of this medicine wears
off completely.

!### Allergy

ContraindicatedTalk to your doctor before receiving TROYCURIUM if you are allergic to
Atracurium or to any other muscle relaxants (such as pancuronium).

!### Lungs

Use with CautionTROYCURIUM should be used with caution in patients with a history of asthma.
Therefore, inform your doctor before receiving it.

!### Heart Disease

Use with CautionTROYCURIUM should be used with caution in patients with heart problems.
Therefore, inform your doctor before receiving it.

!### Use In Pediatrics

Consult your doctorTROYCURIUM should be used in infants, children, and in adolescents (aged above 1
month until 18 years) under close medical supervision. It is not suitable for
use in newborns aged below 1 month of age.

!### Use In Geriatrics

Use with CautionTROYCURIUM should be used with caution in elderly patients. Therefore, consult
your doctor for advice before receiving it.

Others

Before receiving TROYCURIUM, inform your physician if you:

• have problems in blood circulation
• have a history of allergic reactions
• have nerve or muscle disorder (such as myasthenia gravis, poliomyelitis, Eaton-Lambert syndrome etc.)
• have severe electrolyte disorders (abnormal levels of sodium, potassium and chloride in blood)
• are suffering from burns

Interactions

A. Drug-Drug interactions:

Before receiving TROYCURIUM, inform your doctor if you are taking any of the
following medicines:

• lithium (a medicine used to manage bipolar disorder)
• quinine (a medicine used to manage malaria)
• neomycin, streptomycin, kanamycin, gentamicin, lincosamide and polype
• medicines used to manage irregular heartbeat (such as quinidine, amiodarone, propafenone, lidocaine, procainamide, digoxin)
• phenytoin, carbamazepine and thiopental (used to manage fits and seizures)
• diuretics (used to improve urine output) Ex. furosemide, chlorothiazide, acetazolamide
• medicines used to manage heart problems (such as propranolol, diltiazem, nifedipine, nicardipine, oxprenolol, trimetaphan, hexamethonium and verapamil)
• medicines used to manage rheumatism (such as chloroquine, d-penicillamine)
• corticosteroids (used to manage pain and inflammation) such as prednisolone, methylprednisolone
• anesthetics (medicines that causes loss of consciousness) such as isoflurane, desflurane, sevoflurane and enflurane, halothane, ketamine
• dantrolene (a muscle relaxant)
• magnesium sulphate (used to manage abnormally high blood pressure in pregnant women)
• chlorpromazine (a medicine used to manage psychiatric disorders)

Overdosage:

TROYCURIUM will be administered to you only by a doctor or a nurse in a
hospital, and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Atracurium
Pharmacological Category	:	Neuromuscular Blocking Agents
Therapeutic Indication	:	Muscle relaxant
Dosage Forms	:	Injection

More Information

• Keep TROYCURIUM out of reach of children.
• Store TROYCURIUM in a refrigerator between 2-8°C

FAQs About TROYCURIUM

Q: What is the use of TROYCURIUM?

A: TROYCURIUM is a muscle relaxant used to relax your muscles and keeps your
body still (immobile) during a surgery. It also helps with artificial breathing
among patients in intensive care unit (ICU) by relaxing the airway muscles and
facilitates easy insertion of breathing tubes into the airways when artificial
breathing is necessary.

Q: What TROYCURIUM does to my body?

A: TROYCURIUM is a muscle relaxant. It works by blocking the transmission of
nerve signals from the nerve fibers to the muscles. As a result, it causes
muscle relaxation and help you stay immobile during surgeries. TROYCURIUM can
also relax the airway muscles which helps in easy insertion of breathing tubes
into the airways and in artificial breathing.

Q: How long does the effects of TROYCURIUM lasts long?

A: The effects of TROYCURIUM may last between 20-40 minutes depending upon the
dosage administered.

Q: What type of drug is TROYCURIUM?

A: TROYCURIUM is a muscle relaxant. It belongs to neuromuscular blocking agents,
where it blocks the transmission of nerve signals from the nerve fibers to the
muscles.

Q: Why is TROYCURIUM used before surgeries?

A: TROYCURIUM is used prior to surgeries to relax your muscles and to make you
stay immobile by reducing involuntary muscle movements.

Q: Why is TROYCURIUM used along with anesthesia?

A: TROYCURIUM is used along with anesthesia prior to the surgeries to relax your
muscles and to make you immobile. It also helps with artificial breathing among
patients in intensive care unit (ICU) by relaxing the airway muscles and
facilitates easy insertion of breathing tubes into the airways when artificial
breathing is necessary.

Q: What are the side effects of TROYCURIUM?

A: The most common side effects of receiving TROYCURIUM are pain and irritation
at the site of injection, slow or fast heart rate, low or high blood pressure
and difficulty in breathing. Inform your doctor if any of these symptoms worsen.

Q: Can TROYCURIUM be reversed?

A: Yes. The effect of TROYCURIUM reverses on its own and 25% of recovery is
expected to occur in 25 to 45 min and 95% of recovery is expected to occur in 45
to 65 min.

Q: Is TROYCURIUM an anesthetic drug?

A: TROYCURIUM is a muscle relaxant, used as an adjuvant with anesthetic medicine
before undergoing a surgical procedure. It is not an anesthetic.

Q: Will I be staying awake after using TROYCURIUM?

A: TROYCURIUM only relaxes your skeletal muscles and does not affect your
consciousness. However, it might make you feel dizzy or faint. However, when
TROYCURIUM is used along with an anesthetic medication to create numbness before
surgery, you may become unconscious for a while. The anesthesia used along with
TROYCURIUM is the reason for unconsciousness.

Q: Is TROYCURIUM safe for use in pregnant women?

A: TROYCURIUM should be used in pregnant women only if it is considered
necessary by the physician. Therefore, inform your doctor if you are pregnant or
planning to become pregnant before receiving TROYCURIUM. Your doctor will decide
the risks and benefits before administrating TROYCURIUM to you. However,
TROYCURIUM can be used during a caesarean section in pregnant women under close
supervision.