Myostigmin Injection 5ml

Introduction About MYOSTIGMIN 2.5MG INJECTION

MYOSTIGMIN 2.5MG INJECTION contain Neostigmine which belongs to a group of
medicine called Cholinergic drugs. It is mainly used for the management of
myasthenia gravis (a chronic autoimmune disorder in which antibodies destruct
the communication between nerves and muscle, characterised by weakness in the
arm and leg muscles, double vision, trouble speaking and chewing).

MYOSTIGMIN 2.5MG INJECTION is also used to reverse the effects of muscle
relaxants, normalise intestinal movements and manage urinary retention after
surgery. MYOSTIGMIN 2.5MG INJECTION is not recommended for use if you have
blockage in your intestine or face difficulty urinating, have peritonitis or any
condition where your intestines may no longer be functioning.

Before receiving MYOSTIGMIN 2.5MG INJECTION tell your doctor if you have asthma,
fits, stomach ulcer, Parkinson’s disease or any heart problem. MYOSTIGMIN 2.5MG
INJECTION should be used with caution in pregnant and breast-feeding women.

Your doctor will prescribe the right dose of MYOSTIGMIN 2.5MG INJECTION for your
child depending on their age, body weight and disease condition.The most common
side effects of receiving MYOSTIGMIN 2.5MG INJECTION are slow heartbeat, nausea
and vomiting. Contact your doctor if any of the symptoms get worse over time.

Uses Of MYOSTIGMIN 2.5MG INJECTION

Used to:

• Manage myasthenia gravis
• Reverse the effect of muscle relaxants
• Normalise intestinal movements
• Manage urinary retention after surgery

How MYOSTIGMIN 2.5MG INJECTION Works

MYOSTIGMIN 2.5MG INJECTION increases muscle strength by blocking the action of
an enzyme in the body which blocks nerve impulses to muscles. By stopping this
enzyme from working, it strengthens muscles and thus helps in easing of
intestinal movements and urinary retention.

How to use MYOSTIGMIN 2.5MG INJECTION

MYOSTIGMIN 2.5MG INJECTION will be given to you only by a doctor or a nurse into
a vein as an intravenous infusion. Your doctor will decide the correct dose and
duration of management for you depending upon your age, body weight and disease
condition.

Side Effects Of MYOSTIGMIN 2.5MG INJECTION

Common

• increased or decreased heart rate, low blood pressure
• dry mouth, nausea, vomiting
• throat pain, procedural complication or pain
• dizziness, headache, postoperative shivering, prolonged neuromuscular blockade causing paralysis of the affected skeletal muscles
• difficulty in sleeping
• difficulty in breathing
• pruritus (itchy skin)

Rare

Stop receiving MYOSTIGMIN 2.5MG INJECTION and contact your doctor immediately if
you experience any of the following side effects:

• angioedema or a severe allergic reaction (swelling of the face, lips or throat which makes it difficult to swallow or breathe, rash, itching, hives, dizziness)

How To Manage Side Effects

Nausea or Vomiting:

Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to
simple meals. Avoid eating oily or spicy foods. Get adequate rest. Eat when you
feel like it. If symptoms persist, contact your doctor.

Dizziness:

Lie or sit down immediately when you feel dizzy. If you're feeling severe
episode of spinning (vertigo), lie in a dark and quite place with eyes closed.
Try to avoid vehicle driving. If symptom persists, contact your doctor.

Headache:

Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark
room. Drink tea or coffee. Massage on scalp or head with mild pressure. If
symptom persists, contact your doctor.

Dry mouth:

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard
candies to stimulate the flow of saliva. Sip water at regular intervals of time.
Do not use mouthwashes that contain alcohol because they can be drying. If
symptom persists, contact your doctor.

Skin rash:

Avoid hot showers because hot water can irritate the skin. Do not rub or scratch
the rash area. Use sunscreen and protective clothing when outdoors. Regularly
use moisturizers to soothe and hydrate the affected area. If symptom persists,
contact your doctor.

Warning & Precautions

!### Pregnancy

MYOSTIGMIN 2.5MG INJECTION should be used with caution in women who are pregnant
or planning to become pregnant. Consult your doctor for advice.

!### Breastfeeding

MYOSTIGMIN 2.5MG INJECTION should be used with caution in breastfeeding women.
Consult your doctor for advice.

!### Driving and Using Machines

Do not drive or handle any machines if you are affected in any way after
receiving MYOSTIGMIN 2.5MG INJECTION.

!### Kidney

No dose adjustment of MYOSTIGMIN 2.5MG INJECTION is required in patients having
kidney disease, although, close monitoring maybe needed. Consult your doctor for
advice.

!### Liver

No dose adjustment of MYOSTIGMIN 2.5MG INJECTION is required in patients having
liver disease, although, close monitoring maybe needed. Consult your doctor for
advice.

!### Allergy

Do not receive MYOSTIGMIN 2.5MG INJECTION if you are allergic to Neostigmine or
any of the other ingredients of this medicine.

!### Lungs

MYOSTIGMIN 2.5MG INJECTION should be used with caution in patients having
asthma. Consult your doctor for advice.

!### Heart Disease

MYOSTIGMIN 2.5MG INJECTION should be used with caution in patients having heart
disease or a slow pulse. Consult your doctor for advice.

Others

MYOSTIGMIN 2.5MG INJECTION is not recommended for use if you have:

• an intestinal obstruction or difficulty urinating
• peritonitis (infection or inflammation of the outer layer of your stomach or bowel)
• improper bowel functioning

Before receiving MYOSTIGMIN 2.5MG INJECTION, inform your doctor if you have:

• epilepsy (fits)
• vagotonia (sweating, constipation, involuntary movements)
• an overactive thyroid gland
• stomach ulcer
• Parkinson’s Disease
• an anastomosis (an opening made by surgery, trauma or disease) in your intestine

Use in Pediatrics:

Your doctor will prescribe the right dose of MYOSTIGMIN 2.5MG INJECTION for your
child depending on their age, body weight and disease condition.

Use in Geriatrics:

MYOSTIGMIN 2.5MG INJECTION should be received with caution in elderly patients.
Consult your doctor for advice.

Interactions

A. Drug - Drug interactions:

Before receiving MYOSTIGMIN 2.5MG INJECTION, inform your doctor if you are
taking any of the following medicines:

• certain group of medicines used to manage bacterial infections (Ex. amikacin, gentamycin)
• suxamethonium (used to relax muscle during surgery)

Overdosage:

MYOSTIGMIN 2.5MG INJECTION will be administered to you only by a doctor or a
nurse in a hospital and so it is unlikely to receive an overdose. However,
consult your doctor or nurse if you experience any unusual symptoms like nausea,
vomiting, diarrhea, sweating, increased bronchial and salivary secretions and
slow heartbeat.

Synopsis

Drug	:	Neostigmine
Pharmacological Category	:	Anticholinesterases
Therapeutic Indication	:	Myasthenia gravis, To increase muscle strength
Dosage Forms	:	Tablet, Injection

More Information

• Keep MYOSTIGMIN 2.5MG INJECTIONout of reach of children
• Store MYOSTIGMIN 2.5MG INJECTION below 25°C

FAQs About MYOSTIGMIN 2.5MG INJECTION

What should I do if I forget to receive a dose ofMYOSTIGMIN 2.5MG
INJECTION?

Please stick to the prescribed schedule as agreed with your doctor for o
efficacy of MYOSTIGMIN 2.5MG INJECTION management. Tell your doctor whenever you
forget to receive any dose.Can MYOSTIGMIN 2.5MG INJECTION be taken in pregnancy?

Please tell your doctor if you are or think you may be pregnant or are planning
to become pregnant before receiving MYOSTIGMIN 2.5MG INJECTION. Although there
are no known untoward effects of this medicine, your doctor will advise the
correct course of management.

Can MYOSTIGMIN 2.5MG INJECTION be stopped?

Continue receiving MYOSTIGMIN 2.5MG INJECTION until your doctor tells you to
stop, unless you experience any unwanted effects, worsening of your condition or
any new symptoms. Call your doctor in such case.

Can MYOSTIGMIN 2.5MG INJECTION be used in asthmatic patients?

MYOSTIGMIN 2.5MG INJECTION should be used with caution in patients having a lung
disease called asthma. Consult your doctor for advice. Your doctor will
determine a proper dose or select a suitable alternative management for you.

Can I take other medicines with MYOSTIGMIN 2.5MG INJECTION?

Before receiving MYOSTIGMIN 2.5MG INJECTION, inform your doctor if you are
taking, have taken or might take any other medicine, including prescri
over the counter or any herbal medicine, as these might lead to serious side
effects by interacting with each other.