ETOVERSA MR Tablet 10's

Introduction About ETOVERSA MR TABLET

ETOVERSA MR TABLET is a combination of Etoricoxib and Thiocolchicoside which
belongs to the group of medicines called Non-steroidal anti-inflammatory drugs
(NSAID) and Muscle relaxants. It is used to reduce pain and swelling in the
joints and muscles in osteoarthritis, rheumatoid arthritis, ankylosing
spondylitis, gout and muscle spasm. This medicine is also used for the
short-term management after dental surgery for moderate pain. Muscle spasm is
the rapid spontaneous contractions of the muscle, which can be painful and
uncomfortable. When the nerve impulses are damaged or interrupted that control
muscle movement, it could lead to muscle spasms. Symptoms include muscle
tightness, joint stiffness, unusual posture, difficulty in moving and pain in
affected muscles and joints.

ETOVERSA MR TABLET is not recommended for use in patients having inflammatory
bowel disease, severe congestive heart failure, pe
disease. Consult your doctor for advice. Before taking ETOVERSA MR TABLET,
inform your doctor if you have blood disorders, kidney problems, liver problems
or heart problems.

ETOVERSA MR TABLET is not recommended to use among pregnant and breastfeeding
women. The most common side effects of this medicine are stomach pain, dry
socket, edema, dizziness, headache, palpitations, arrhythmia, constipation,
diarrhea, indigestion, gastritis, nausea and vomiting. Consult your doctor if
the above side effects worsens or persist for a longer duration.

Uses Of ETOVERSA MR TABLET

• Used to reduce pain, swelling in the joints and muscles in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout and muscle spasm

How ETOVERSA MR TABLET Works

ETOVERSA MR TABLET reduces pain and swelling in the joints and muscles, whereas
Etoricoxib works by blocking the release of certain chemical messengers that
cause pain and inflammation and Thiocolchicoside works on the centers in the
brain and spinal cord to relieve muscle stiffness or spasm and improves pain and
movement of muscles.

How to use ETOVERSA MR TABLET

ETOVERSA MR TABLET reduces pain and swelling in the joints and muscles, whereas
Etoricoxib works by blocking the release of certain chemical messengers that
cause pain and inflammation and Thiocolchicoside works on the centers in the
brain and spinal cord to relieve muscle stiffness or spasm and improves pain and
movement of muscles.

Side Effects Of ETOVERSA MR TABLET

Common

• stomach pain
• dry socket
• edema
• dizziness
• headache
• palpitations
• uneven heart rhythm (arrhythmia)
• increase in blood pressure
• wheezing or shortness of breath
• constipation
• gastritis
• flatulence
• diarrhea
• heartburn
• indigestion
• nausea
• vomiting
• inflammation of the esophagus
• mouth ulcers
• changes in blood tests
• bruising
• weakness and fatigue, flu-like illness
• drowsiness

Uncommon

• anorexia
• unusual dark urine
• itching
• fever
• fatigue

Rare

• confusion
• restlessness
• liver problems
• low blood levels of sodium
• liver failure
• severe skin reactions
• urticaria

Stop taking ETOVERSA MR TABLET and contact your doctor immediately if you
experience the following side effects:

• shortness of breath, chest pain, ankle swelling
• yellowing of the skin and eyes
• severe or continual stomach pain or stools become black
• allergic reaction (symptoms include ulcers or blistering, swelling of the face, lips, tongue or throat which may cause difficulty in breathing)

How To Manage Side Effects

!### Constipation

Eat plenty of fiber-rich foods such as fresh fruits, vegetables and cereals and
drink plenty of water. Exercise more regularly.

!### Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor.

!### Loss Of Appetite

Eat when you are hungry. Eat smaller meals more often than usual. Snack only
when you're hungry. Eat a nutritious snack that is rich in calories and protein,
such as dried fruit and nuts.

!### Nausea And Vomiting

Take this medicine with or just after meals. Stick to simple meals. Avoid eating
rich or spicy food. Consult your doctor for advice if you experience nausea for
a long time.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller and frequent
meals. Keep a heat pad on your stomach. If the symptom does not improve, contact
your doctor.

Warning & Precautions

!### Pregnancy

ContraindicatedETOVERSA MR TABLET is not recommended for use in pregnant women. Consult your
doctor for advice.

!### Breastfeeding

ContraindicatedETOVERSA MR TABLET is not recommended for use in breastfeeding women. Consult
your doctor for advice.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you experience dizziness or sleepiness.
Consult your doctor for advice.

!### Alcohol

Consult your doctorAvoid consum
your existing condition.

!### Kidney

ContraindicatedETOVERSA MR TABLET is not recommended for use in patients having severe kidney
disease. Consult your doctor for advice.

!### Liver

ContraindicatedETOVERSA MR TABLET is not recommended for use in patients having severe liver
problems. Consult your doctor for advice.

!### Allergy

ContraindicatedDo not take ETOVERSA MR TABLET if you are allergic to Etoricoxib,
Thiocolchicoside or to any of the other ingredients of this medicine.

!### Heart Disease

Consult your doctorETOVERSA MR TABLET is not recommended for use if you have or had high blood
pressure that has not been controlled by management, heart problems (heart
failure), angina (chest pain), heart attack or bypass surgery. It should be used
with caution if you have any mild to moderate heart problems. Consult your
doctor for advice.

!### Use In Pediatrics

ContraindicatedETOVERSA MR TABLET is not recommended for use in children and adolescents (below
16 years of age). Consult your doctor before taking the medicine.

!### Use In Geriatrics

Use with CautionETOVERSA MR TABLET should be used with caution in elderly patients (aged above
65 years). Consult your doctor before taking it.

Others

ETOVERSA MR TABLET is not recommended for use if you:

• have stomach ulcer or bleeding in the stomach or intestines
• have Crohn’s disease, Ulcerative colitis, or Colitis (inflammatory bowel disease)
• have any kind of stroke, and muscles problems
• have peripheral arterial disease

Tell your physician before taking this medicine if you:

• had dehydration (a prolonged bout of vomiting or diarrhea)
• had swelling due to fluid retention
• have being managed for an infection
• have high cholesterol, diabetes
• are a smoker
• have epilepsy

Interactions

A. Drug-Drug interactions:

Inform your physician, if you are taking:

• medicines used to thin blood (Ex. warfarin)
• medicines used to manage infections (Ex. rifampicin)
• medicine used for suppressing the immune system, and often used in rheumatoid arthritis (Ex. methotrexate, ciclosporin, or tacrolimus)
• medicine used to manage depression (Ex. lithium)
• medicines used to control high blood pressure and heart failure (Ex. enalapril, ramipril, losartan, valsartan)
• medicine used as diuretics
• medicine used to manage heart failure and irregular heart rhythm (Ex. digoxin)
• medicine used to manage asthma (Ex. salbutamol)
• birth control pills
• hormone replacement therapy
• medicine used to relieve pain and reduce the risk of serious problems like heart attacks and strokes (Ex. aspirin)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your
doctor immediately.

Synopsis

Drug	:	Etoricoxib, Thiocolchicoside
Pharmacological Category	:	Non-steroidal anti-inflammatory drugs (NSAID), Muscle relaxants
Therapeutic Indication	:	Manages inflammatory musculoskeletal disorders associated with painful muscle spasm
Dosage Forms	:	Tablet, Capsule, Soft Gel Capsules

More Information

Storage

• Keep out of reach of children
• Store at room temperature

FAQs About ETOVERSA MR TABLET

Q: Does ETOVERSA MR TABLET cause any dizziness?

A: Yes. This medicine can cause dizziness in some people. Try to rest and relax.
Get enough sleep. Avoid driving or operating any machines while you are feeling
dizzy. Avoid consum
symptom persists for a longer time, contact your doctor for advice.

Q: What precaution to be taken if I miss a dose of ETOVERSA MR TABLET?

A: If a dose of ETOVERSA MR TABLET is missed, then take the next dose at the
usual time. Do not take a double dose to make up for a forgotten missed dose.

Q: Can I stop ETOVERSA MR TABLET if I feel well?

A: Do not stop taking ETOVERSA MR TABLET without consulting with your doctor,
even if you feel better. Stopping may worsen the condition.

Q: How to take ETOVERSA MR TABLET?

A: Take ETOVERSA MR TABLET as advised by your doctor. Swallow the medicine as a
whole and do not crush or chew the medicine.

Q: Is it safe to use ETOVERSA MR TABLET during pregnancy?

A: ETOVERSA MR TABLET is generally not recommended to use in pregnant women.
Consult your doctor before taking it.