Tiganex 50mg Injection 5ml

Introduction About TIGANEX 50MG INJECTION

TIGANEX 50MG INJECTION contains a medicine Tigecycline which belongs to a group
of medicines called Antibiotics. It is used to manage serious infections such as
complicated infection of the skin and soft tissues (the tissue below the skin),
excluding diabetic foot infections.

TIGANEX 50MG INJECTION is also used to manage complicated infection in the
abdomen. It is used when your doctor thinks that other antibiotics will not suit
you.

Before receiving TIGANEX 50MG INJECTION, inform your doctor if you have liver
diseases, slow or poor wound healing, diarrhoea, blockage of the bile ducts,
allergy to tetracycline antibiotics or bleeding disorders.

TIGANEX 50MG INJECTION should be used with caution in pregnant and
breast-feeding women. TIGANEX 50MG INJECTION is not recommended for use in
children below 8 years of age. TIGANEX 50MG INJECTION can be used in elderly
patients, however, consult with your doctor before receiving.

The most common side effects of receiving TIGANEX 50MG INJECTION are nausea,
vomiting, diarrhoea, headache, injection site pain or inflammation or dizziness.
Contact your doctor if the symptoms worsen or doesn’t improve.

Uses Of TIGANEX 50MG INJECTION

Manage serious infections such as:

• complicated infection of the skin and soft tissues (the tissue below the skin), excluding diabetic foot infections
• complicated infection in the abdomen

How TIGANEX 50MG INJECTION Works

TIGANEX 50MG INJECTION acts on the bacteria and disrupt the important life
functions of the bacteria. It interferes with the present bacteria and disrupts
the cell membrane along with hampering its various cellular function which leads
to bacterial death.

How to use TIGANEX 50MG INJECTION

TIGANEX 50MG INJECTION will be given to you only by a doctor or a nurse into a
vein as an intravenous infusion or injection. Your doctor will decide the
correct dose and duration of TIGANEX 50MG INJECTION for you depending upon your
age, body weight and disease condition.

Side Effects Of TIGANEX 50MG INJECTION

Common

• nausea, vomiting
• diarrhoea
• abscess (collection of pus), infections
• laboratory measurement of decreased ability to form blood clots (low platelets)
• dizziness
• injection site pain, inflammation, swelling and clotting
• abdominal pain, dyspepsia (stomachache and indigestion), anorexia (loss of appetite)
• increases in liver enzymes
• hyperbilirubinaemia (excess of bile pigments in the blood)
• pruritus (itching), rash
• poor or slow wound healing
• headache
• increase in amylase (may cause inflammation of pancreas characterised by pain in abdomen and back)
• increased blood urea nitrogen (frequent urination, fatigue, itching, swelling in ankles and feet)
• pneumonia
• low blood sugar
• sepsis (severe infections in the body and blood stream)/se
• low protein levels in the blood

Uncommon

• jaundice (yellow coloration of the skin)
• inflammation of the liver

Rare

• low fibrinogen levels in the blood (a protein involved in blood clotting)

Stop receiving TIGANEX 50MG INJECTION and contact your doctor immediately if you
experience any of the following side effects:

• pseudomembranous colitis
• serious bowel inflammation symptoms such as bloody diarrhoea, abdominal pain or fever
• severe abdominal pain, nausea and vomiting (pancreatitis)

How To Manage Side Effects

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor. Ask for
your doctor’s advice if diarrhoea doesn’t improve.

Nausea:

Stick to simple meals while receiving TIGANEX 50MG INJECTION. Avoid eating rich
or spicy food. Do not take any medication on your own. Ask for your doctor’s
advice if nausea doesn’t improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Rest in a
quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your
doctor’s advice if headache doesn’t improve.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, oily or
sweet foods. Avoid carbonated drinks. Ask for your doctor’s advice if vomiting
doesn’t improve.

Dizziness:

Lie or sit down immediately when you feel dizzy. If you're feeling severe
episode of spinning(vertigo), lie in a dark and quite place with eyes closed.
Try to avoid vehicle driving. Discuss with your doctor if the symptom worsens.

Stomach pain:

Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad
on your stomach. Take your physic

Loss of appetite:

Eat when you are hungry. Eat a nutritious snack rich in calories and protein,
such as dried fruit and nuts. If the symptom does not show improvement, consult
your doctor.

Low blood sugar:

Eat glucose tablets or another high sugar snack, like sweets, biscuits or fruit
juice (always carry glucose tablets or a high sugar snack). Take enough rest.
Consult your doctor if symptoms don’t improve.

Warning & Precautions

!### Pregnancy

TIGANEX 50MG INJECTION should be used with caution in pregnant women as it may
cause foetal harm. If you are pregnant, think you may be pregnant or are
planning to have a baby, ask your doctor for advice before receiving TIGANEX
50MG INJECTION.

!### Breastfeeding

TIGANEX 50MG INJECTION should be used with caution in breast feeding women as it
is not known if it passes through breast milk. Consult with your doctor before
receiving it.

!### Driving and Using Machines

Do not drive or use machinery if you feel dizzy after receiving TIGANEX 50MG
INJECTION.

!### Liver

TIGANEX 50MG INJECTION should be used with caution in patients suffering from
liver disease. Consult your doctor before receiving it.

!### Allergy

Do not receive TIGANEX 50MG INJECTION if you are allergic to Tigecycline or
tetracycline class antibiotics such as minocycline, doxycycline or any other
ingredients of this medicine.

Others

Before receiving TIGANEX 50MG INJECTION, inform your doctor if you have:

• slow or poor wound healing
• diarrhoea
• blockage of the bile ducts
• allergy to tetracycline antibiotics (skin sensitization to sun light, staining on developing teeth, inflammation of pancreas, decreased ability to form blood clot)
• bleeding disorders

Use in pediatrics:

TIGANEX 50MG INJECTION is not recommended for use in children less than 8 years
of age due to the lack of data on safety and efficacy in this age group. Also,
it may cause permanent dental defects such as staining on the developing teeth.
Consult with your child’s doctor.

Use in geriatrics:

TIGANEX 50MG INJECTION can be used in elderly patients. However, consult your
doctor before receiving it.

Interactions

A. Drug - Drug interactions:

Before receiving TIGANEX 50MG INJECTION, inform your doctor if you are taking
any of the following medicine:

• anticoagulants such as warfarin (used to manage blood clotting)
• contrace
• tacrolimus or cyclosporine (used to suppress the immune system e.g., in organ transplants)

Overdosage:

TIGANEX 50MG INJECTION will be administered to you only by a doctor or a nurse
in a hospital and so it is unlikely to receive an overdose. However, consult
your doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Tigecycline
Pharmacological Category	:	Glycylcycline
Therapeutic Indication	:	Complicated infection of the skin, soft tissues and abdomen
Dosage Forms	:	Injection

More Information

• Keep TIGANEX 50MG INJECTION out of reach of children
• Store TIGANEX 50MG INJECTION below 25°C

FAQs About TIGANEX 50MG INJECTION

Can TIGANEX 50MG INJECTION be used in children?

TIGANEX 50MG INJECTION is not recommended for use in children less than 8 years
of age due to the lack of data on safety and efficacy in this age group. Also,
it may cause permanent dental defects such as staining on the developing teeth.
Consult with your child’s doctor.

Can TIGANEX 50MG INJECTION cause diarrhoea?

Yes, TIGANEX 50MG INJECTION may cause diarrhoea in some individuals. Drink lots
of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking
any medicine on your own for managing diarrheoa. Consult your doctor if the
symptom did not improve.

How much time does it take to administer TIGANEX 50MG INJECTION?

TIGANEX 50MG INJECTION will be given to you only by a doctor or a nurse into a
vein as an intravenous infusion or injection over a period of 30 to 60 minutes.
Your doctor will decide the correct dose and duration of TIGANEX 50MG INJECTION
for you depending upon your age, body weight and disease condition.

Can I take TIGANEX 50MG INJECTION during liver disease?

TIGANEX 50MG INJECTION should be used with caution in patients suffering from
liver disease such as cholestasis (blockage of the bile ducts). Consult your
doctor before receiving this medicine.

Does TIGANEX 50MG INJECTION affects my ability to drive?

Do not drive or operate any machines if you feel dizzy, after receiving TIGANEX
50MG INJECTION. You can continue doing your activities as soon as you feel
normal again.

Do I need to undergo any tests while being managed with TIGANEX 50MG
INJECTION?

Although antibiotics including TIGANEX 50MG INJECTION, fight certain bacteria,
other bacteria and fungi may continue to grow. This is called overgrowth. Your
doctor will monitor you closely for any potential infections and may prescribe a
different antibiotic specific for the type of infection present.

Useful Diagnostic Tests

• Complete Blood Count