Nixidox Capsule 10'S

Introduction About NIXIDOX CAPSULE

NIXIDOX CAPSULE is a combination of Doxycycline and Lactic Acid Bacillus, which
belong to the groups of medicines called antibiotics and probiotics,
respectively. It is used in adults prone to intra-abdominal bacterial infection
and to manage antibiotic-associated diarrhoea.

Before taking NIXIDOX CAPSULE, inform your doctor about your pre-existing
conditions, allergies or if you are taking any other medicines. NIXIDOX CAPSULE
is not recommended for use in pregnant women, breastfeeding women or children
(younger than 8 years), so consult your doctor before taking it.

The most common side effects of taking NIXIDOX CAPSULE are loss of appetite,
nausea, vomiting, diarrhoea, rash, light sensitivity, hives and haemolytic
anaemia. Consult your doctor if any of your symptoms get worse.

Uses Of NIXIDOX CAPSULE

• Manage intra-abdominal bacterial infection
• Manage antibiotic-associated diarrhea

How NIXIDOX CAPSULE Works

NIXIDOX CAPSULE improves gastrointestinal symptoms where doxycycline gets
accumulated inside the bacteria, gets attached to the 30S subunit of the
bacterial ribosome and inhibits bacterial protein synthesis; lactobacillus
restores the natural microbial flora within the digestive tract and helps in the
breakdown of food, resulting in the production of lactic acid, hydrogen peroxide
and other by-products.

How to use NIXIDOX CAPSULE

Take NIXIDOX CAPSULE as advised by your physician. Swallow the medicine as a
whole with a glass of water. Do not crush or chew the medicine. Your doctor will
determine your correct dose and duration based on your age, body weight and
disease condition.

Side Effects Of NIXIDOX CAPSULE

Common

• loss of appetite, nausea, vomiting, diarrhea
• rash, light sensitivity, hives
• hemolytic anemia (red blood cells are destroyed faster than they can be restored)

Rare

Stop taking NIXIDOX CAPSULE and contact your doctor immediately if you
experience any of the following side effects:

• permanent discoloration of the teeth to yellow-grey-brown (second half of pregnancy, infancy and childhood up to 8 years of age)
• clostridium difficile-associated diarrhea
• light sensitivity causing extreme sunburn reaction

How To Manage Side Effects

Loss of appetite:

Eat when you are hungry. Eat smaller meals more often than usual. Snack only
when you're hungry. Eat a nutritious snack rich in calories and protein, such as
dried fruit and nuts. Consult your doctor if your symptom does not improve or
persist.

Nausea:

Take NIXIDOX CAPSULE with or just after, meals. Stick to simple meals. Avoid
eating oily or spicy foods. Consult your doctor if your symptom does not improve
or persist.

Vomiting:

Get adequate rest. Drink lots of fluids, especially water. Have small sips if
you feel sick. Eat when you feel like eating; you don't have to eat or avoid any
specific foods. Do not take any medicine for vomiting without your doctor's
consultation. Consult your doctor if your symptom does not improve or persist.

Diarrhoea:

Drink lots of fluids, like water or fruit juice, to keep yourself hydrated.
Check with your doctor before taking any medicine for diarrhoea. Consult your
doctor if your symptom does not improve or persist.

Warning & Precautions

!### Pregnancy

NIXIDOX CAPSULE is not recommended for use by pregnant women. Consult your
doctor before taking it.

!### Breastfeeding

NIXIDOX CAPSULE is not recommended for use by breastfeeding women. Consult your
doctor before taking it.

!### Driving and Using Machines

Consult your doctor if you feel any side effects during management with NIXIDOX
CAPSULE that may stop you from driving or using machines.

!### Allergy

Do not take NIXIDOX CAPSULE if you are allergic to Doxycycline, Lactic acid
bacillus, other tetracyclines or any of the other ingredients of this medicine.

Others

Before taking NIXIDOX CAPSULE, inform your doctor about your pre-existing
conditions.

Use in Pediatrics:

NIXIDOX CAPSULE is not recommended for use by children under 8 years of age.
Consult your doctor before taking it.

Use in Geriatrics:

Your doctor will prescribe the right dose of NIXIDOX CAPSULE depending on your
age, body weight and health condition. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking NIXIDOX CAPSULE, inform your doctor if you are taking any of the
following medicines:

• medicines used to manage blot clots (Ex. dabigatran, rivaroxaban)
• medicines used to reduce acidity (Ex. aluminum, calcium, magnesium, bismuth subsalicylate)
• iron-containing medicines
• medicines used to manage pregnancy (Ex. norethindrone, ethinyl estradiol)
• medicines used to manage fits (Ex. phenobarbital, carbamazepine, phenytoin)

Overdosage:

If you or anyone else accidentally take too much of NIXIDOX CAPSULE, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Doxycycline, Lactic acid bacillus
Pharmacological Category	:	Tetracycline antibiotics, Probiotics
Therapeutic Indication	:	Intra-abdominal bacterial infection, Antibiotic associated diarrhoea
Dosage Forms	:	Tablet, Capsule

More Information

• Keep NIXIDOX CAPSULE out of reach from children
• Store below 30°C

FAQs About NIXIDOX CAPSULE

Can NIXIDOX CAPSULE be given to children?

NIXIDOX CAPSULE is not recommended for use in children (under 8 years of age) as
it may cause permanent discoloration of teeth. Your doctor will decide on the
correct dose or select a suitable alternative management for your child.

What if I forget to take a dose of NIXIDOX CAPSULE?

If you forget to take a dose of NIXIDOX CAPSULE, take it as soon as you
remember. However, omit the missed dose if it's almost time for the next one. Do
not take the medicine twice to make up for the missed dose.

Can NIXIDOX CAPSULE be stopped?

Continue taking NIXIDOX CAPSULE until your doctor tells you to stop, unless you
experience any unwanted effects, worsening of your condition or new symptoms.
Contact your doctor in such a case.

How should NIXIDOX CAPSULE be taken? Can it be crushed?

No. Do not break, crush or chew NIXIDOX CAPSULE. Take it as advised by your
physician. Swallow it with a glass of water. Your doctor will determine your
correct dose and duration based on your age, body weight and disease condition.

What is NIXIDOX CAPSULE used for?

NIXIDOX CAPSULE is used in adults prone to intra-abdominal bacterial infection
and antibiotic-associated diarrhoea.

Can NIXIDOX CAPSULE cause vomiting?

Vomiting is a common side effect of NIXIDOX CAPSULE. In such cases, get adequate
rest and drink lots of fluids, especially water. Have small sips if you feel
sick. Eat when you feel like eating; you don't have to eat or avoid any specific
foods. Do not take any medicine for vomiting without your doctor's consultation.
If vomiting does not get better, contact your doctor.

What should I tell my doctor before taking NIXIDOX CAPSULE?

Patients taking NIXIDOX CAPSULE must inform their doctor about their
pre-existing conditions or allergies. Patients should also tell their doctor if
they are pregnant or breastfeeding. Consult your doctor if you experience
anything different.

Can NIXIDOX CAPSULE be taken during pregnancy?

NIXIDOX CAPSULE is not recommended for use in pregnancy. If you are pregnant,
think you may be pregnant or are planning to get pregnant, consult your doctor
before taking it. Inform your doctor immediately if you become pregnant during
this management.

Can I take other medicines with NIXIDOX CAPSULE?

Before taking NIXIDOX CAPSULE, inform your doctor if you have taken or might
take any other medicine, including prescri
medicine, as these might cause serious side effects by interacting with each
other.