Solotrate CR 30mg Tablet 10'S

Introduction About SOLOTRATE CR 30MG TABLET

SOLOTRATE CR 30MG TABLET contains Isosorbide Mononitrate which belongs to the
group of medicines called Nitrate vasodilators. It is used to manage chronic
angina pectoris and it is not recommended for use in sudden or acute angina.
Angina pectoris is defined as a sudden, sharp, severe pain originating from the
apex of heart and radiating to the left shoulder. The pain is severe and
crushing, and it is characterized by feeling of pressure and suffocation, behind
breastbone.

SOLOTRATE CR 30MG TABLET is not recommended for use in patients suffering from
lung disease that result in low levels of oxygen in the body (hypoxemia) or
cardiac conditions such as low blood volume, low blood pressure, and thickened
cardiac muscles (cardiac myopathy) or shock (vascular collapse). Before taking
SOLOTRATE CR 30MG TABLET, inform your doctor if you have a history of liver or
kidney diseases, glaucoma, thyroid problems, or if you suffer from low body
temperature.

Your doctor may advise you to follow lifestyle changes such as diet changes
(taking foods low in fat, salt or sugar) and do regular mild exercises to
achieve better results during management with this medicine. It is not
recommended for use in children and should be used with caution in elderly
patients.

SOLOTRATE CR 30MG TABLET should be used with caution in pregnant and
breast-feeding women, so consult your doctor before taking it. The common side
effects of taking SOLOTRATE CR 30MG TABLET are headache, tiredness, dizziness,
nausea, decreased blood pressure (hypotension) and rapid heartbeat
(palpitations). Consult your doctor if any of the above side effects worsen.

Uses Of SOLOTRATE CR 30MG TABLET

• Manage Angina Pectoris (chest pain)

How SOLOTRATE CR 30MG TABLET Works

SOLOTRATE CR 30MG TABLET helps to relax the blood vessels and muscles of the
heart, which causes the space inside the blood vessels to widen. This helps to
ease the flow of blood in the blood vessels of the heart and provides relief
from the pain associated with blockage of vessels as seen in angina.

How to use SOLOTRATE CR 30MG TABLET

Take SOLOTRATE CR 30MG TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration of SOLOTRATE CR 30MG TABLET for you
depending upon your age, body weight and disease condition.

Side Effects Of SOLOTRATE CR 30MG TABLET

Common

• headache
• tiredness
• dizziness
• nausea
• decreased blood pressure (hypotension)
• rapid heartbeat (palpitations)

Uncommon

• reddening of the face due to increased flow of blood (flushing)
• vomiting
• diarrhea

Rare

• fainting or collapsing
• itchy skin
• rash

Stop taking SOLOTRATE CR 30MG TABLET and consult your doctor immediately if you
experience any of the following side effects:

• severe decreased blood pressure (signs include pale and cold skin or skin having blue tinge, rapid and shallow breathing along with elevated heart rate, weak pulse resulting in dizziness, confusion and/or anxiety)
• loss of consciousness indicative of circulatory collapse which can result in insufficient supply of oxygen to the vital body organs like brain and kidneys

How To Manage Side Effects

!### Dizziness Or Drowsiness

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully,
do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid
coffee, cigarettes, alcohol, and drugs. Consult your doctor if the symptom gets
worse.

Headache

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to
be relaxed and stress free. Apply pain relieving balm on your forehead if
necessary. Consult your doctor if the symptom does not improve.

!### Nausea And Vomiting

Take SOLOTRATE CR 30MG TABLET with or just after meals. Stick to simple meals.
Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately
after eating. Consult your doctor if the symptom does not improve.

!### Tiredness

Drink plenty of fluid and eat balanced diet and frequent meals. Do regular
minimal exercise (mild walking) and follow regular sleep schedule. Consult your
doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

Monitoring requiredSOLOTRATE CR 30MG TABLET should be used with caution in pregnant women and who
are planning for pregnancy unless considered clearly considered necessary.
Consult your doctor before taking SOLOTRATE CR 30MG TABLET.

!### Breastfeeding

Use with CautionSOLOTRATE CR 30MG TABLET should be used with caution in breast-feeding women due
to lack of safety data. Consult your doctor before taking SOLOTRATE CR 30MG
TABLET.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel dizzy after taking SOLOTRATE CR
30MG TABLET.

!### Alcohol

Consult your doctorAvoid consum
might increase the risk of dizziness and sometimes fainting also.

!### Kidney

ContraindicatedSOLOTRATE CR 30MG TABLET is not recommended for use if you had or have or
suspect of having disorders of the kidney. Consult your doctor before taking
SOLOTRATE CR 30MG TABLET.

!### Liver

ContraindicatedSOLOTRATE CR 30MG TABLET is not recommended for use if you had or have or
suspect of having disorders of the liver. Consult your doctor before taking
SOLOTRATE CR 30MG TABLET.

!### Allergy

ContraindicatedDo not take SOLOTRATE CR 30MG TABLET if you are allergic to isosorbide
mononitrate or other nitrates (such as isosorbide dinitrate).

!### Lungs

ContraindicatedSOLOTRATE CR 30MG TABLET is not recommended for use in patients having lung
disease resulting in low levels of oxygen in the body (hypoxaemia). Consult your
doctor before taking it.

!### Heart Disease

ContraindicatedSOLOTRATE CR 30MG TABLET is not recommended for use in patients with sudden
anginal attack, low blood volume, low blood pressure, thickened cardiac muscles
(cardiac myopathy), hardened heart valves (stenosis), compression of the heart
due to fluid around it (cardiac tamponade) and vascular collapse (shock).
Consult your doctor before taking SOLOTRATE CR 30MG TABLET.

!### Use In Pediatrics

ContraindicatedSOLOTRATE CR 30MG TABLET is not recommended for use in children. Consult child’s
doctor for advice.

!### Use In Geriatrics

Use with CautionSOLOTRATE CR 30MG TABLET should be used with caution in elderly patients. Your
doctor may adjust the dose of SOLOTRATE CR 30MG TABLET due to increased risk of
side effects in elderly individuals. Consult your doctor before taking it

Others

SOLOTRATE CR 30MG TABLET is not recommended for use if you have:

• elevated pressure inside the eyes (glaucoma)
• disease related to increased pressure inside the head (brain haemorrhage)
• a head injury

Before taking SOLOTRATE CR 30MG TABLET, inform your doctor if you:

• are diagnosed with an underactive thyroid gland
• are undernourished
• have a sustained low body temperature (hypothermia)
• have eye disorders

Interactions

A. Drug-Drug Interactions

Before taking SOLOTRATE CR 30MG TABLET, inform your doctor if you are taking any
of the following medicines:

• medicines used to manage male impotency (Ex. sildenafil, tadalafil)
• medicines to manage high blood pressure such as calcium channel blockers (Ex. verapamil)

Overdosage: If you or anyone else accidentally take too much of
SOLOTRATE CR 30MG TABLET, consult your doctor immediately or visit the nearby
hospital. Symptoms of overdosage are pulsating/throbbing headache, reddening of
the skin along with an increase in the temperature, blurred vision, rapid drop
in blood pressure and fainting.

Synopsis

Drug	:	Isosorbide mononitrate
Pharmacological Category	:	Nitrate vasodilators
Therapeutic Indication	:	Angina
Dosage Forms	:	Tablet, Capsule

More Information

• Keep SOLOTRATE CR 30MG TABLET out of reach of children.
• Store at room temperature

FAQs About SOLOTRATE CR 30MG TABLET

Q: What is SOLOTRATE CR 30MG TABLET used for?

A: SOLOTRATE CR 30MG TABLET is used to manage chronic angina pectoris (chest
pain) and it is not recommended for use in sudden or acute angina. Angina
pectoris is defined as a sudden, sharp, severe pain originating from the apex of
heart and radiating to the left shoulder. The pain is severe and crushing, and
it is characterized by feeling of pressure and suffocation, behind
breastbone.

Q: Can SOLOTRATE CR 30MG TABLET be used in elderly patients?

A: Yes, SOLOTRATE CR 30MG TABLET should be used with caution in elderly
patients. Your doctor may adjust the dose of SOLOTRATE CR 30MG TABLET due to
increased risk of side effects in elderly individuals. Consult your doctor
before taking it Q: Is SOLOTRATE CR 30MG TABLET safe to use during
pregnancy?

A: SOLOTRATE CR 30MG TABLET should be used with caution in pregnant women and
who are planning for pregnancy unless considered clearly considered necessary.
Consult your doctor before taking SOLOTRATE CR 30MG TABLET if you are pregnant
or planning to get pregnant

Q: CanSOLOTRATE CR 30MG TABLET be used in patients with heart disease?

A: SOLOTRATE CR 30MG TABLET is not recommended for use in patients with sudden
anginal attack, low blood volume, low blood pressure, thickened cardiac muscles
(cardiac myopathy), hardened heart valves (stenosis), compression of the heart
due to fluid around it (cardiac tamponade) and vascular collapse (shock).
Consult your doctor before taking SOLOTRATE CR 30MG TABLET.

Q: What are the common side effects of SOLOTRATE CR 30MG TABLET?

A: The common side effects of taking SOLOTRATE CR 30MG TABLET are headache,
tiredness, dizziness, nausea, decreased blood pressure (hypotension) and rapid
heartbeat (palpitations). Consult your doctor if any of the side effect worsen
or bothers you.

Useful Diagnostic Tests

• Electrocardiogram (ECG)
• Chest x-ray
• Chest CT
• Coronary CT angiography
• Cardiac MRI
• Coronary angiography
• Echocardiogram