IVABID 7.5mg Tablet 14's

Introduction About IVABID 7.5MG TABLET

IVABID 7.5MG TABLET contains Ivabradine which belongs to the group of medicines
called Hyperpolarization-activated cyclic nucleotide-gated channel blockers.
IVABID 7.5MG TABLET is used to manage symptomatic stable angina pectoris (chest
pain) in adult patients who are intolerant/incapable to take heart medicines
(such as beta blockers) and whose heart rate is over/equal to 70 beats per
minute.

It is also used to manage chronic heart failure in adult patients whose heart
rate is over/equal to 75 beats per minute which are used as a combination
therapy with beta-blockers or in adult patients who are contraindicated to use
beta blockers.

IVABID 7.5MG TABLET is not recommended for use in patients allergic to
ivabradine. It is also not recommended for use in patients suffering from very
low blood pressure, heart problems (such as unstable angina, cardiogenic shock),
severe kidney disease, and/or severe liver disease.

Before taking IVABID 7.5MG TABLET, inform your doctor if you have mild to
moderate low blood pressure, chronic eye retinal disease, recent stroke
(cerebral attack), heart rhythm disorders (such as irregular heartbeat,
palpitation, increase in chest pain), and/or moderate liver disease.

IVABID 7.5MG TABLET is generally not recommended for use in pregnant and
breast-feeding women which is also not recommended for use in children and
adolescents (aged below 18 years). The medicine is advised to be used with
caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of taking IVABID 7.5MG TABLET are brief moments of
increased brightness (due to sudden changes in light intensity), slow heart
rate, uncontrolled blood pressure, headache, dizziness, and/or blurred vision.
Consult your doctor if any of these symptoms worsen.

Uses Of IVABID 7.5MG TABLET

• Symptomatic stable angina pectoris (chest pain) in adult patients (with heart rate above/equal to 70 beats/minute)
• Chronic heart failure in adult patients (with heart rate above/equal to 75 beats/minute)

How IVABID 7.5MG TABLET Works

IVABID 7.5MG TABLET works by reducing the heart rate which leads to low oxygen
requirement of the heart resulting in improved blood supply throughout the body
(with each hear beat) thus providing relief from angina pectoris and managing
the occurrence of chronic heart failure in affected individuals.

How to use IVABID 7.5MG TABLET

Tablet:

Take IVABID 7.5MG TABLET as advised by your physician. Swallow the medicines
with a glass of water. Do not crush or chew the medicine. Your physician will
decide the correct dose and duration for you depending on your age, body weight
and disease condition.

Orally Disintegrating Tablet:

Take IVABID 7.5MG TABLET as advised by your physician. Place IVABID 7.5MG
TABLET inside your mouth and allow it to dissolve completely. Do not swallow or
chew the medicine.. Your physician will decide the correct dose and duration for
you depending on your age, body weight and disease condition.

Side Effects Of IVABID 7.5MG TABLET

Common

• brief moments of increased brightness (due to sudden changes in light intensity)
• slow heart rate
• signs of atrial fibrillation (irregular rapid contraction of heart) such as chest pain, pounding heartbeat, tiredness
• uncontrolled blood pressure
• headache, dizziness, blurred vision

Uncommon

• racing heartbeat
• nausea, constipation, diarrhoea, abdominal pain
• sudden internal/external spinning sensation
• difficulty breathing
• muscle spasms
• skin rash
• signs of angioedema such as swollen face, tongue/throat, difficulty in breathing/swallowing
• low blood pressure, fainting, tiredness, weakness
• double vision, impaired vision

Rare

• red itchy welts, itching, skin reddening
• feeling unwell

How To Manage Side Effects

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a
pain-relieving balm on the head if necessary. Do not consume alcohol. Contact
your doctor if the symptom does not improve.

Dizziness:

Try to rest and get enough sleep. Try to avoid driving or operating any tools or
machines while you feel dizzy. Limit consum
dizziness. Consult and inform your doctor if the symptom worsens.

Nausea:

Try to take IVABID 7.5MG TABLET with or just after a meal or a snack. Stick to
simple meals. Avoid eating rich or spicy food. Consult your doctor if the
symptom gets worse.

Constipation:

Try to eat high-fibre foods such as vegetables, cereals, fresh fruit, and drink
plenty of water. Involve in regular exercise (going for a daily walk or run) and
if this does not help, consult and inform your doctor to receive alternate
managements for constipation.

Diarrhoea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on
your own to manage diarrhoea. Consult your doctor and inform them if the symptom
gets worse.

Warning & Precautions

!### Pregnancy

IVABID 7.5MG TABLET is not recommended for use during pregnancy and in women
planning for pregnancy. Women of childbearing potential should use reliable
contrace
before taking the medicine.

!### Breastfeeding

IVABID 7.5MG TABLET is not recommended for use in breastfeeding women. Consult
your doctor before taking the medicine.

!### Driving and Using Machines

Do not drive or operate any machines after taking IVABID 7.5MG TABLET since it
may cause temporary blindness (due to sudden changes in light intensity) which
may after your ability to concentrate while driving or operating machines.

!### Kidney

IVABID 7.5MG TABLET should be used with caution in patients with severe kidney
disease. Consult your doctor before taking the medicine.

!### Liver

IVABID 7.5MG TABLET is not recommended for use in patients with severe liver
disease. It should be used with caution in patients with moderate liver disease.
Consult your doctor before taking the medicine.

!### Allergy

Do not take IVABID 7.5MG TABLET if you are allergic to ivabradine, and/or any
other ingredients of this medicine.

!### Heart Disease

IVABID 7.5MG TABLET is not recommended for use in patients with heart problems
such as slow resting heart rate (beats below 70/minute), cardiogenic shock,
heart rhythm disorders (such as sick sinus syndrome, sino-atrial block, heart
block), heavy heart attack, and/or severe heart failure. It should be used with
caution in patients with other heart rhythm disorders (such as irregular
heartbeat, palpitation, increase in chest pain), sustained atrial fibrillation,
long QT syndrome, slow heartbeat (associated with signs such as tiredness,
dizziness, shortness of breath), and/or bundle branch block (type of severe
heart failure). Consult your doctor before taking the medicine.

Others

IVABID 7.5MG TABLET is not recommended for use if you:

• suffer from very low blood pressure
• have unstable angina (a severe form of chest pain)

Before taking IVABID 7.5MG TABLET, inform your doctor if you:

• had a recent stroke (cerebral attack)
• suffer from mild to moderate low blood pressure (after change in antihypertensive management)
• have chronic eye retinal disease

Use in Paediatrics:

IVABID 7.5MG TABLET is generally not recommended for use in children and
adolescents (aged below 18 years). Consult your doctor before taking the
medicine.

Use in Geriatrics:

IVABID 7.5MG TABLET should be used with caution in elderly patients (aged above
65 years). Consult your doctor before taking the medicine.

Interactions

A.Drug - Drug interactions:

Before taking IVABID 7.5MG TABLET, inform your doctor if you are taking any of
the following medicine:

• medicines used to manage fungal infections (Ex. fluconazole, ketoconazole, itraconazole)
• rifampicin (medicine used to manage tuberculosis)
• barbiturates (medicines used for difficulty sleeping or epilepsy)
• phenytoin (used for epilepsy)
• hypericum perforatum/St John’s Wort (herbal medicines used for depression)
• medicines used to manage heart rhythm disorders (Ex. quinidine, disopyramide, sotalol, ibutilide, amiodarone)
• bepridil (medicine used to manage angina pectoris)
• medicines to manage anxiety, schizophrenia or other psychoses (Ex. pimozide, ziprasidone, sertindole)
• medicines used to manage malaria (Ex. mefloquine,halofantrine)
• intravenous erythromycin (medicine used to manage bacterial infections in different parts of the body)
• pentamidine (medicine used in the management *of pneumocystis pneumonia, leishm
• cisapride (used for acid reflux)
• diuretics (medicines used to manage oedema, high blood pressure) Ex. furosemide, hydrochlorothiazide, indapamide
• clarithromycin, josamycin, telithromycin,erythromycin (medicines used for bacterial infections)
• nelfinavir, ritonavir (medicines used to manage HIV infections)
• nefazodone (medicine used to manage depression)
• diltiazem, verapamil (medicines used to manage high blood pressure/angina pectoris)

B.Drug -Food interaction:

Avoid drinking grapefruit juice while taking IVABID 7.5MG TABLET as it may alter
the effect of the medicine.

Overdosage:

If you or anyone else accidentally take too much of IVABID 7.5MG TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose are
breathlessness and tiredness.

Synopsis

Drug	:	Ivabradine
Pharmacological Category	:	Hyperpolarization-activated cyclic nucleotide-gated channel blockers
Therapeutic Indication	:	Symptomatic stable angina, Chronic Heart failure
Dosage Forms	:	Tablet

More Information

• Keep IVABID 7.5MG TABLET out of the sight and reach of children
• Store at room temperature

FAQs About IVABID 7.5MG TABLET

What is IVABID 7.5MG TABLET used for?

IVABID 7.5MG TABLET is used to manage symptomatic stable angina pectoris (chest
pain) in adult patients who are intolerant/incapable to take heart medicines
(such as beta blockers) which is also used to manage chronic heart failure in
adult patients whose heart rate is over/equal to 75 beats per minute.

How IVABID 7.5MG TABLET works?

IVABID 7.5MG TABLET works by reducing the heart rate which leads to low oxygen
requirement of the heart resulting in improved blood supply throughout the body
(with each hear beat) thus providing relief from angina pectoris and managing
the occurrence of chronic heart failure in affected individuals.

What are the most common side effects of taking IVABID 7.5MG TABLET?

The most common side effects of taking IVABID 7.5MG TABLET are brief moments of
increased brightness (due to sudden changes in light intensity), slow heart
rate, uncontrolled blood pressure, headache, dizziness, and/or blurred vision.
Consult your doctor if any of these symptoms worsen.

How to take IVABID 7.5MG TABLET?

Take IVABID 7.5MG TABLET as advised by your physician. Swallow the medicine with
a glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration for you depending upon your age, body weight and
disease condition.

C

No, IVABID 7.5MG TABLET is not recommended for use during pregnancy and in women
planning for pregnancy as it may cause harm to the foetus. Women of childbearing
potential should use reliable contrace
7.5MG TABLET. Consult your doctor before taking the medicine.

Useful Diagnostic Tests

• Electrocardiogram
• Stress test
• Coronary angiography