Roliflo OD 2mg Capsule 10'S

Introduction About ROLIFLO OD 2MG CAPSULE

ROLIFLO OD 2MG CAPSULE is a combination of Tamsulosin and Tolterodine which
belongs to the group of medicines called Alpha-blockers and Antimuscarinics
respectively. It is used in men to manage symptoms of benign prostatic
hyperplasia which is a condition marked by an enlarged prostate gland that
pushes against the urethra and the urinary bladder resulting in the blockade of
urine flow which is generally characterized by urinary difficulty.

Avoid taking ROLIFLO OD 2MG CAPSULE, if you suffer from dizziness when you want
to sit up or stand up from a lying position, have urinary retention (inability
to pass urine), uncontrolled narrow-angle glaucoma (high pressure in the eyes
with loss of eyesight), myasthenia gravis (excessive weakness of the muscles)
and severe ulcerative colitis (ulceration and inflammation of the colon).

Before taking ROLIFLO OD 2MG CAPSULE, inform your doctor if you have
difficulties in passing urine, hiatal hernia (a condition marked by the bulging
of the upper part of stomach), planning to undergo cataract or glaucoma (eye
disorder that cause blindness) surgery or have liver, kidney disease.

ROLIFLO OD 2MG CAPSULE is not recommended for use in pregnant and breastfeeding
women since the medicine is indicated only for men. ROLIFLO OD 2MG CAPSULE is
also not recommended for use in children and adolescents (aged below 18 years).

The most common side effects of taking ROLIFLO OD 2MG CAPSULE are dizziness, dry
mouth, tiredness headache, stomach pain and blurred vision. Consult your doctor
if any of these side effects get worse during or after management with ROLIFLO
OD 2MG CAPSULE.

Uses Of ROLIFLO OD 2MG CAPSULE

• Manage symptoms of benign prostatic hyperplasia (such as difficulty in urination, urinary dribbling, urinary urgency and frequent urination)

How ROLIFLO OD 2MG CAPSULE Works

ROLIFLO OD 2MG CAPSULE reduces the need or urge to pass urine more frequently or
urgently by relaxing the muscles in the prostate and urinary bladder, where
Tamsulosin relaxes the muscles in the prostate and urinary bladder and
Tolterodine provides relief by inhibiting the bladder contraction that causes
relaxation of the muscles of the urinary bladder resulting in the management of
frequent, urgent or controlled urination.

How to use ROLIFLO OD 2MG CAPSULE

Take ROLIFLO OD 2MG CAPSULE as advised by your physician. Swallow ROLIFLO OD 2MG
CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor
will decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

Side Effects Of ROLIFLO OD 2MG CAPSULE

Common

• difficulties with ejaculation (sperm expulsion)
• little or no semen ejaculated (expuled) at sexual climax
• cloudy urine following sexual climax
• dizziness, headache
• dry mouth
• sinusitis (inflammation of sinuses)
• sleepiness
• indigestion
• dry eyes, blurred vision
• constipation
• abdominal pain
• excessive air or gas in the stomach or the intestine
• painful or difficult urination
• tiredness
• extra fluid in the body causing swelling (Ex. in the ankles)
• diarrhea

Uncommon

• light-headedness or fainting (due to postural low blood pressure)
• swelling and irritation inside the nose
• nausea, vomiting
• weakness
• signs of allergic reactions such as rash, itching
• nervousness
• prickling and tingling sensation in fingers and toes
• vertigo (spinning sensation)
• signs of heart disease such as sensing fast heartbeat, heart failure, irregular heartbeat
• inability to empty bladder
• chest pain
• memory impairment

Rare

• short-term loss of consciousness

Stop taking ROLIFLO OD 2MG CAPSULE and contact your doctor if you experience any
of the following side effects:

• signs of stevens-johnson syndrome (a serious hypersensitivity reaction) such as purplish spots or patches on the skin, blisters on the skin, peeling of the skin, high fever, joint pain and/or eye inflammation
• signs of angioedema (painless swelling under the skin) such as swollen face, tongue or pharynx, difficulty to swallow, itchy skin rash and difficulty in breathing
• signs of hypersensitivity allergic reaction such as skin rash, itching and difficulty in breathing
• signs of heart failure such as chest pain, difficulty breathing or getting tired easily (even at rest), difficulty breathing at night, and swelling of the legs

How To Manage Side Effects

Diarrhea:

Drink lot of fluids such as water to keep yourself hydrated. Try to avoid taking
any medicine on your own to manage diarrhea and consult your doctor if the
symptom gets worse.

Constipation:

Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and
drink plenty of water. Try doing exercise regularly (going for a daily walk or
run). If this does not help, inform your doctor for receiving alternate
managements for constipation.

Dizziness:

Try to rest and relax and get enough sleep. Try to avoid driving or operating
any tools or machines while you are feeling dizzy. Limit your consum
alcohol, as it can aggravate your dizziness. Consult and inform your doctor if
the symptom does not improve.

Nausea and vomiting:

Try to take ROLIFLO OD 2MG CAPSULE with or just after a meal or a snack. Stick
to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if
the symptom gets worse.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that
contain alcohol because they can make your mouth dry, use mouthwash that is used
only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco
products. Consult your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

ROLIFLO OD 2MG CAPSULE is not recommended for use in pregnant women since it is
used only in men.

!### Breastfeeding

ROLIFLO OD 2MG CAPSULE is not recommended for use in breastfeeding women since
it is used only in men.

!### Driving and Using Machines

Do not drive or operate any tools or machines if you experience dizziness,
tiredness or affect your sight while taking ROLIFLO OD 2MG CAPSULE.

!### Alcohol

Avoid consum
alter the effect of this medicine.

!### Kidney

ROLIFLO OD 2MG CAPSULE should be used with caution in patients with severely
impaired kidney function or patients with kidney problems. Consult your doctor
for advice before taking ROLIFLO OD 2MG CAPSULE.

!### Liver

ROLIFLO OD 2MG CAPSULE is not recommended for use in patients with serious
infection of the liver. It is used with caution in patients with liver
conditions. Consult your doctor for advice before taking ROLIFLO OD 2MG
CAPSULE.

!### Allergy

ROLIFLO OD 2MG CAPSULE is not recommended for use if you are allergic to
Tamsulosin or Tolterodine.

!### Heart Disease

ROLIFLO OD 2MG CAPSULE should be used with caution in patients with heart
problems such as slow heartrate, weak heart muscle, reduced blood flow to the
heart, irregular heartbeat and heart failure. Consult your doctor before taking
ROLIFLO OD 2MG CAPSULE.

Others

ROLIFLO OD 2MG CAPSULE is not recommended for use if you:

• have swelling due to allergic reaction after using some drugs
• suffer from dizziness while sitting or standing up from the lying position
• have or already had malaise (sense of feeling unwell) while you urinate or after urinating
• inability to pass urine from the bladder (urinary retention)
• have an uncontrolled narrow-angle glaucoma (eye disorder that cause blindness)
• suffer from myasthenia gravis (excessive weakness of the muscles)
• suffer from severe ulcerative colitis (inflammation and ulceration of the colon)
• suffer from a toxic megacolon (a type of severe colon disease)

Before taking ROLIFLO OD 2MG CAPSULE, inform your doctor if you:

• are planning to undergo cataract or glaucoma (eye disorder that cause blindness) surgery
• have difficulty while passing urine
• have a gastro-intestinal disease that affects the passage and/or digestion of food
• suffer from neurological disorders that affect your blood pressure, bowel or sexual function
• have a hiatal hernia (condition marked by the bulging of upper part of stomach)
• suffer from severe constipation
• intolerant to certain sugars
• hypokalemia (condition of low levels of potassium in blood)
• hypocalcemia (condition of low levels of calcium in blood)
• hypomagnesaemia (condition of low levels of magnesium in blood)

Use in Pediatrics:

ROLIFLO OD 2MG CAPSULE is not recommended for use in children and adolescents
(aged below 18 years). Consult your child’s doctor for advice.

Use in Geriatrics:

ROLIFLO OD 2MG CAPSULE should be used with caution in elderly patients (aged 65
years or above). Consult your doctor before taking ROLIFLO OD 2MG CAPSULE.

Interactions

A. Drug-Drug Interactions:

Before taking ROLIFLO OD 2MG CAPSULE, inform your doctor, if you are taking any
of the following medicines:

• diclofenac (medicine used to manage aches and pains)
• warfarin (medicine used to manage blood clotting)
• another alpha 1 adrenergic receptor (medicine used to manage benign prostatic hyperplasia) Ex. prazosin, terazosin and doxazosin
• ketoconazole, itraconazole (medicine used to manage fungal infection)
• antibiotics (medicines used to manage bacterial infections) Ex. erythromycin, clarithromycin
• medicines used in the management of HIV (Ex. indinavir, nelfinavir, ritonavir)
• medicines that affect the passage of food (Ex. metoclopramide and cisapride)
• medicines used to manage irregular heartbeat (Ex. amiodarone, sotalol, quinidine, procainamide)
• other antimuscarinic agents (medicines used to manage post operative nausea and vomiting) Ex. atropine and scopolamine
• medicines used to block the action of a neurotransmitter (chemicals that enable the brain to provide a variety of functions) Ex. donepezil

B. Drug-Food Interactions:

Avoid consum
it may alter the effect of this medicine. Consult your doctor before taking
ROLIFLO OD 2MG CAPSULE.

Overdosage:

If you or anyone else accidentally takes too much of ROLIFLO OD 2MG CAPSULE,
consult your doctor immediately or visit the nearby hospital. Overdosage symptom
of ROLIFLO OD 2MG CAPSULE is drop in blood pressure.

Synopsis

Drug	:	Tamsulosin, Tolterodine
Pharmacological Category	:	Alpha-blocker, Antimuscarinic
Therapeutic Indication	:	Benign prostate enlargement
Dosage Forms	:	Capsule

More Information

• Keep ROLIFLO OD 2MG CAPSULE out of reach of children
• Store ROLIFLO OD 2MG CAPSULE at room temperature

FAQs About ROLIFLO OD 2MG CAPSULE

What is ROLIFLO OD 2MG CAPSULE used for?

ROLIFLO OD 2MG CAPSULEis used in men to manage symptoms of benign prostatic
hyperplasia which is a condition marked by an enlarged prostate gland that
pushes against the urethra and the urinary bladder resulting in the blockade of
urine flow which is generally characterized by urinary difficulty.

What happens if you forget to take ROLIFLO OD 2MG CAPSULE?

If you have forgotten to take ROLIFLO OD 2MG CAPSULE at the scheduled time, take
it anytime later during the day. If you happen to discover this fact only on the
next day, continue with the usual dosage scheme. Try not to take a double dose
to make up for the missed dosage.

What happens if you suddenly stop ROLIFLO OD 2MG CAPSULE?

Do not stop ROLIFLO OD 2MG CAPSULE on your own since the medicine might cause
some side effects. It is advisable to consult your doctor before stopping the
management with ROLIFLO OD 2MG CAPSULE.

Can ROLIFLO OD 2MG CAPSULE be used in patients with kidney problems?

ROLIFLO OD 2MG CAPSULE should be used with caution in patients with severely
impaired kidney function or patients with kidney problems. Consult your doctor
for advice before taking ROLIFLO OD 2MG CAPSULE.

Is it safe to drive after taking ROLIFLO OD 2MG CAPSULE?

ROLIFLO OD 2MG CAPSULE might cause dizziness, tiredness or affect your sight. If
you experience these side effects, try to avoid driving or operating heavy
machines. Consult your doctor before taking ROLIFLO OD 2MG CAPSULE.

Useful Diagnostic Tests

• Urine flow study
• Prostate-specific antigen (PSA) blood test
• Urine analysis test