Soliact 10mg Tablet 10'S

Introduction About SOLIACT

SOLIACT contains Solifenacin which belongs to the group of medicines called
Urinary antispasmodics. It is used to manage the signs of overactive bladder
(such as sudden urge to pass urine, increased frequency of passing urine, unable
to control urine and wetting yourself because you couldn’t go the bathroom).

SOLIACT reduces the activity of an overactive bladder and enables you to wait
longer before having to go to the bathroom. Try to take SOLIACT at the same time
each day to achieve maximum benefits. It can be taken with or without meals.

Before taking SOLIACT inform your doctor if you have any liver, kidney or heart
problems. You must also inform your doctor if you have any other problems in the
bladder that obstructs urine flow or if you have glaucoma, constipation, stomach
problems (such as tear or block in the gut), muscle weakness or urinary tract
infections as a precaution.

SOLIACT is not recommended for use in patients who are not able to pass urine
(urinary retention) and in patients with severe bowel problems (such as toxic
megacolon). It is not suitable for use in pregnant or breastfeeding women and in
children aged below 18 years.

The most common side effects of taking SOLIACT are dry mouth, blurred vision,
constipation, nausea, abdominal fullness, stomach pain, burping, heartburn and
stomach discomfort. Inform your doctor if any of the above side effects worsen.

Uses Of SOLIACT

• Manage signs of overactive bladder (such as sudden urge to pass urine, increased urine frequency, unable to control urine or wetting yourself)

How SOLIACT Works

SOLIACT is a muscle relaxant which relaxes the smooth muscles surrounding the
bladder. This helps your bladder to hold more volume of urine and controls urine
flow. As a result, it reduces the activity of an overactive bladder and enables
you to wait longer before having to go to the bathroom.

How to use SOLIACT

Take SOLIACT as advised by your physician. Swallow the medicine with a glass of
water. Do not crush or chew the medicine. SOLIACT can be taken with or without
food.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition.

Side Effects Of SOLIACT

Common

• dry mouth
• blurred vision
• nausea
• constipation, indigestion, stomach pain
• sense of fullness in the stomach, burping, heartburn

Uncommon

• urinary tract infection, bladder infection
• sleepiness
• changes in taste
• dry eyes, nose or throat
• dry skin
• difficulty in passing urine
• tiredness
• fluid build-up in the lower legs (oedema)

Rare

• accumulation of a large amount of hardened stool in the large intestine (faecal impaction)
• dizziness, headache
• itching, rash

Stop taking SOLIACT and contact your doctor immediately if you experience any of
the following side effects:

• signs of allergic reactions (such as skin rash, itching and swelling of the face, lips, mouth, tongue or throat causing difficulty in swallowing or breathing)
• severe skin rash with blistering and peeling of the skin

How To Manage Side Effects

Nausea:

Take SOLIACT with or just after meals. Stick to simple meals. Avoid eating oil
rich or spicy foods. Consult your doctor if your nausea worsens.

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Do not consume excessive
alcohol, as it could aggravate your dizziness. Consult your doctor if your
dizziness worsens.

Constipation:

Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals.
Drink plenty of fluids. Exercise more regularly. Consult your doctor if this
side effect bothers you.

Blurred vision:

Close your eyes and relax. Do not strain your eyes by looking at mobile phones,
laptops, or television. Avoid driving or operating any heavy tools or machines
while your vision is blur. Consult your doctor if you experience blurred vision
for a prolonged period.

Warning & Precautions

!### Pregnancy

SOLIACT is not recommended for use in pregnant women unless considered necessary
by the physician. Therefore, consult your doctor before taking it.

!### Breastfeeding

SOLIACT is not recommended for use in breastfeeding women as it may pass through
the breast milk. Therefore, consult your doctor before taking it.

!### Driving and Using Machines

Do not drive or operate any machines if you experience sleepiness, tiredness or
blurred vision after taking SOLIACT.

!### Kidney

SOLIACT is not recommended for use in patients with moderate to severe kidney
problems (including in those who undergo dialysis). Therefore, consult your
doctor before taking it.

!### Liver

SOLIACT is not recommended for use in patients with moderate to severe liver
problems. Therefore, consult your doctor before taking it.

!### Allergy

Do not take SOLIACT if you are allergic to Solifenacin.

!### Heart Disease

SOLIACT should be used with caution in patients with heart problems (such as
heart failure). Therefore, consult your doctor before taking it.

Others

SOLIACT is not recommended for use if you:

• have urinary retention (unable to pass urine)
• have a severe stomach or bowel condition (including toxic megacolon, ulcerative colitis)
• have myasthenia gravis (severe muscle weakness)
• have glaucoma

Before taking SOLIACT, inform your doctor if you:

• have any bladder obstruction
• have difficulty in passing urine
• have constipation or any obstruction in the gut
• have a stomach tear (hiatus hernia)
• have heartburn
• have nerve pain (autonomic neurpathy)
• have urinary tract infection

Use in pediatrics:

SOLIACT is not recommended for use in children and adolescents (aged below 18
years of age). Therefore, consult your doctor before taking it.

Use in geriatrics:

SOLIACT should be used with caution in elderly patients. Therefore, consult your
doctor before taking it.

Interactions

A. Drug – Drug Interaction:

Before taking SOLIACT, inform your doctor if you are taking any of the following
medicines such as:

• medicines used to manage fungal infections (Ex. ketoconazole, itraconazole)
• medicines used to manage viral infections (Ex. ritonavir, nelfinavir)
• medicines used to manage high blood pressure (Ex. verapamil, diltiazem)
• other anticholinergic medicines (used to increased heart rate, reduce body secretions and increase body movements) Ex. ipratropium, atropine
• medicines used to manage reflux disease (Ex. metoclopramide and cisapride)
• medicines such as bisphosphonates used to manage bone loss
• rifampicin (a medicine used to manage tuberculosis)
• medicines used to manage fits (Ex. phenytoin, carbamazepine)

B. Drug – Food Interactions:

SOLIACT can be taken with or without food.

Overdosage:

If you or anyone else accidentally took more SOLIACT, consult your doctor
immediately or visit the nearby hospital. Symptoms of overdose are headache, dry
mouth, dizziness, drowsiness, blurred vision, hallucinations, over-excitability,
seizures, difficulty in breathing, increased heart rate, accumulation of urine
in the bladder and dilated pupils.

Synopsis

Drug	:	Solifenacin
Pharmacological Category	:	Anticholinergics
Therapeutic Indication	:	Overactive bladder
Dosage Forms	:	Tablet

More Information

• Keep SOLIACT out of reach of children
• Store SOLIACT at room temperature

FAQs About SOLIACT

Will the use of SOLIACT controls urination?

Yes. SOLIACT helps your bladder to hold more volume of urine and controls urine
flow. It reduces the activity of an overactive bladder and enables you to wait
longer before having to go to the bathroom.

What are the side effects of SOLIACT?

The most common side effects of taking SOLIACT are dry mouth, blurred vision,
constipation, nausea, abdominal fullness, stomach pain, burping, heartburn and
stomach discomfort. Inform your doctor if any of the above side effects worsen.

Can SOLIACT affect blood pressure?

SOLIACT generally did not increase heart rate or blood pressure. But when the
medicine is used in patients with history of heart diseases, it may increase the
risk of heart rate and blood pressure. Therefore, always consult your doctor
before taking the medicine.

What happens if you stop taking SOLIACT?

Do not stop taking SOLIACT without consulting your doctor as it may make your
symptoms reappear. Take SOLIACT for the stipulated duration advised by your
doctor to achieve maximum benefits.

How does SOLIACT help in overactive bladder?

SOLIACT helps your bladder to hold more volume of urine and controls urine flow.
It reduces the activity of an overactive bladder and enables you to wait longer
before having to go to the bathroom.

Can you take SOLIACT every day?

Yes. Generally SOLIACT is prescribed once a day. However, your doctor will
evaluate your health condition and suggest you whether you can take SOLIACT or
not.

Who should not take SOLIACT?

SOLIACT is not recommended for use in patients having severe liver or kidney
diseases, severe stomach or bowel condition (ulcerative colitis), myasthenia
gravis or glaucoma. Therefore, consult your doctor for advice.

What is the use of SOLIACT?

SOLIACT is used to manage the signs of overactive bladder (such as sudden urge
to pass urine, increased frequency of passing urine, unable to control urine and
wetting yourself because you couldn’t go the bathroom).

How SOLIACT works in my body?

SOLIACT is a muscle relaxant which relaxes the smooth muscles surrounding the
bladder. This helps your bladder to hold more volume of urine and controls urine
flow. As a result, it reduces the activity of an overactive bladder and enables
you to wait longer before having to go to the bathroom.

Can SOLIACT cause dry mouth?

SOLIACT may cause dry mouth in some individuals. To manage this, drink plenty of
water to keep yourself hydrated. However, inform your doctor if this side effect
troubles you.

Can SOLIACT be used during pregnancy?

SOLIACT is not recommended for use in pregnant women unless considered necessary
by the physician. Therefore, consult your doctor before taking it.

What is the best time to take SOLIACT?

SOLIACT can be taken at any time of the day. However, consult your doctor for
advice.

Can SOLIACT cause dizziness?

Yes. SOLIACT rarely causes dizziness in some individuals. If you experience
dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating
any tools or machines while you are feeling dizzy. Consult your doctor if your
dizziness worsens.

How and when should I take SOLIACT?

Take SOLIACT as advised by your physician. Swallow the medicine with a glass of
water. Do not crush or chew the medicine. [GBNKEYEORD] can be taken with or
without food. Your doctor will decide right time of administration for you after
analyzing your health condition.

Will SOLIACT affect fertility?

No. SOLIACT does not affect fertility.  It only improves urinary symptoms
associated with overactive bladder by relaxing the smooth muscles surrounding
the bladder.

How long will SOLIACT take to manage my disease?

It may take up to 4 weeks for SOLIACT to show the results. However, this period
varies from person to person based on their disease condition. Consult your
doctor if your symptoms are not relived even after taking SOLIACT for a
prolonged period.

What to do if I forgot to take SOLIACT?

If you forgot to take a dose of SOLIACT take it as soon as you remember.
However, if it is time to take the next dose, skip the missed dose and take the
next dose at regular times. Do not take a double dose to compensate a missed
dose.

Will taking a higher dose of SOLIACT be more effective?

No. Do not take a higher dose of SOLIACT than the prescribed one without
consulting your doctor. Taking a higher dose of SOLIACT may not be beneficial.
Instead, it can cause serious side effects. If the prescribed dose is not
effective for you, consult your doctor. Your doctor may prescribe a suitable
higher dose or suggest an alternative therapy after evaluating your disease
condition.