MIRAGO S 25 Tablet 10's

Introduction About MIRAGO S 25 TABLET

MIRAGO S 25 TABLET is a combination of Mirabegron and Solifenacin which belongs
to the group of medicines called Urinary Antispasmodics. It is used to manage
the signs of overactive bladder (such as sudden urge to pass urine, increased
frequency of passing urine, unable to control urine or wetting yourself because
you couldn’t go the bathroom). MIRAGO S 25 TABLET reduces the activity of an
overactive bladder and enables you to wait longer before having to go to the
bathroom. Try to take MIRAGO S 25 TABLET at the same time each day to achieve
maximum benefits. It can be taken with or without meals.

Before taking MIRAGO S 25 TABLET inform your doctor if you have any liver,
kidney or heart problems. You must also inform your doctor if you have any other
problems in the bladder that obstructs urine flow or if you have glaucoma,
constipation, stomach problems (such as tear or block in the gut), muscle
weakness or urinary tract infections as a precaution. MIRAGO S 25 TABLET is not
recommended for use in patients who are not able to pass urine (urinary
retention) and in patients with severe bowel problems (such as toxic megacolon).

It is not suitable for use in pregnant or breastfeeding women and in children
aged below 18 years. The most common side effects of taking MIRAGO S 25 TABLET
are dry mouth, blurred vision, constipation, nausea, abdominal fullness, stomach
pain, burping, heartburn, headache and dizziness. Consult your doctor if any of
these side effect worsens.

Uses Of MIRAGO S 25 TABLET

• Used to manage signs of overactive bladder (such as sudden urge to pass urine, increased urine frequency, unable to control urine or wetting yourself)

How MIRAGO S 25 TABLET Works

MIRAGO S 25 TABLET is a urinary muscle relaxant medicine which relaxes the
smooth muscles surrounding the bladder. This helps your bladder to hold more
volume of urine and can control urine flow. As a result, it reduces signs of
overactive bladder and enables you to wait longer before having to go to the
bathroom.

How to use MIRAGO S 25 TABLET

Take MIRAGO S 25 TABLET as advised by your physician. Swallow the medicine with
a glass of water. Do not crush or chew the medicine. MIRAGO S 25 TABLET can be
taken with or without food. Your doctor will decide the correct dose and
duration of therapy for you depending upon your age, body weight and disease
condition.

Side Effects Of MIRAGO S 25 TABLET

Common

• dry mouth
• blurred vision
• nausea
• constipation
• indigestion
• stomach pain
• diarrhea
• sense of fullness in the stomach
• burping, heartburn
• fast heart rate
• urinary tract infection
• headache
• dizziness

Uncommon

• bladder infections
• vaginal infections
• vaginal itching
• sleepiness
• changes in taste
• dry eyes, nose or throat
• dry skin
• difficulty in passing urine
• tiredness
• fluid build-up in the lower legs
• stomach infections
• increased blood pressure
• skin rash, itching

Rare

• accumulation of a large amount of hardened stool in the large intestine (faecal impaction)

Stop taking MIRAGO S 25 TABLET and contact your doctor immediately if you
experience any of the following side effects:

• signs of allergic reactions (such as skin rash, itching and swelling of the face, lips, mouth, tongue or throat causing difficulty in swallowing or breathing)
• severe skin rash with blistering and peeling of the skin
• severe migraine headache
• irregular heart rhythm

Warning & Precautions

!### Pregnancy

Monitoring requiredMIRAGO S 25 TABLET is not recommended for use in pregnant women unless
considered necessary by the physician. Therefore, consult your doctor before
taking it.

!### Breastfeeding

ContraindicatedMIRAGO S 25 TABLET is not recommended for use in breastfeeding women as it may
pass through the breast milk. Therefore, consult your doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you experience sleepiness, tiredness or
blurred vision after taking MIRAGO S 25 TABLET.

!### Kidney

Consult your doctorMIRAGO S 25 TABLET is not recommended for use in patients with moderate to
severe kidney problems (including in those who undergo dialysis). It should be
used with caution in patients with other mild kidney problems. Therefore,
consult your doctor before taking it.

!### Liver

Consult your doctorMIRAGO S 25 TABLET is not recommended for use in patients with moderate to
severe liver problems. It should be used with caution in patients with other
mild liver problems. Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take MIRAGO S 25 TABLET if you are allergic to Solifenacin or Mirabegron
or any other ingredients of this disease.

!### Heart Disease

Consult your doctorMIRAGO S 25 TABLET is not recommended for use in patients with uncontrolled high
blood pressure. It should be used with caution in patients with heart problems
(such as heart failure or abnormal heart rhythm). Therefore, consult your doctor
before taking it.

!### Use In Pediatrics

ContraindicatedMIRAGO S 25 TABLET is not recommended for use in children and adolescents (aged
below 18 years of age). Therefore, consult your doctor before giving the
medicine.

!### Use In Geriatrics

Use with CautionMIRAGO S 25 TABLET should be used with caution in elderly patients. Therefore,
consult your doctor before taking it.

Others

MIRAGO S 25 TABLET is not recommended for use if you:

• have urinary retention
• have a severe stomach or bowel condition
• have severe muscle weakness
• have glaucoma

Before taking MIRAGO S 25 TABLET, inform your doctor if you:

• have any bladder obstruction
• have difficulty in passing urine or a weak urine stream
• have constipation or any obstruction in the gut
• have a stomach tear
• have heartburn
• have nerve pain
• have urinary tract infection

Interactions

A. Drug-Drug Interaction:

Before taking MIRAGO S 25 TABLET, inform your doctor if you are taking any of
the following medicines such as:

• medicines used to manage fungal infections (Ex. ketoconazole, itraconazole)
• medicines used to manage viral infections (Ex. ritonavir, nelfinavir)
• medicines used to manage high blood pressure (Ex. verapamil, diltiazem)
• other anticholinergic medicines (used to increased heart rate, reduce body secretions and increase body movements) Ex. ipratropium, atropine
• medicines used to manage reflux disease (Ex. metoclopramide, cisapride)
• medicines such as bisphosphonates used to manage bone loss
• rifampicin (a medicine used to manage tuberculosis)
• medicines used to manage fits (Ex. phenytoin, carbamazepine)
• medicines used for mental illness (such as thioridazine, mesoridazine, haloperidol and chlorpromazine)
• medicines used to manage abnormal heart rhythm (such as digoxin, propafenone or flecainide, quinidine, sotalol, procainamide, ibutilide, dofetilide and amiodarone)
• medicines used for depression (Ex. imipramine or desipramine)
• dabigatran (used to reduce the risk of blood clots)
• medicines used to manage allergic rhinitis (Ex. cetirizine, levocetirizine, montelukast)
• medicines used to manage bacterial infections (Ex. pentamidine, moxifloxacin, erythromycin, clarithromycin)

B. Drug-Food Interactions:

MIRAGO S 25 TABLET can be taken with or without food. Consult your doctor for
advice.

Overdosage:

If you or anyone else accidentally took more of MIRAGO S 25 TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose are
headache, dry mouth, dizziness, drowsiness, blurred vision, hallucinations,
over-excitability, seizures, difficulty in breathing, increased heart rate,
increased blood pressure, accumulation of urine in the bladder and dilated
pupils.

Synopsis

Drug	:	Mirabegron, Solifenacin
Pharmacological Category	:	Beta 3-adrenoceptor agonist, Muscarinic Receptor Antagonists
Therapeutic Indication	:	Overactive bladder
Dosage Forms	:	Tablet, Combi pack, Combi kit

More Information

Storage

• Keep MIRAGO S 25 TABLET out of reach of children
• Store MIRAGO S 25 TABLET at room temperature

FAQs About MIRAGO S 25 TABLET

Q: What is the use of MIRAGO S 25 TABLET?

A: MIRAGO S 25 TABLET is used to manage the signs of overactive bladder (such as
sudden urge to pass urine, increased frequency of passing urine, unable to
control urine and wetting yourself because you could not go the bathroom).

Q: Will the use of MIRAGO S 25 TABLET controls urination?

A: Yes. MIRAGO S 25 TABLET helps the bladder to hold more volume of urine and
controls urine flow. It reduces the activity of an overactive bladder and
enables you to wait longer before having to go to the bathroom.

Q: What are the side effects of MIRAGO S 25 TABLET?

A: The most common side effects of taking MIRAGO S 25 TABLET are dry mouth,
blurred vision, headache, dizziness, constipation, nausea, abdominal fullness,
stomach pain, burping, heartburn and stomach discomfort. Inform your doctor if
any of the above side effects worsen.

Q: Can MIRAGO S 25 TABLET affect blood pressure?

A: Yes. MIRAGO S 25 TABLET may raise blood pressure in some individuals.
Therefore, it should be used with caution in patients with history of
hypertension.

Q: What happens if you stop taking MIRAGO S 25 TABLET?

A: Do not stop taking MIRAGO S 25 TABLET without consulting your doctor as it
may make your symptoms reappear. Take MIRAGO S 25 TABLET for the stipulated
duration advised by your doctor to achieve maximum benefits.

Q: How does MIRAGO S 25 TABLET help in overactive bladder?

A: MIRAGO S 25 TABLET helps your bladder to hold more volume of urine and
controls urine flow. It reduces the activity of an overactive bladder and
enables you to wait longer before having to go to the bathroom.

Q: Can you take MIRAGO S 25 TABLET every day?

A: Yes. MIRAGO S 25 TABLET is prescribed once a day. However, your doctor will
evaluate your health condition and suggest you whether you can take MIRAGO S 25
TABLET or not.

Q: Who should not take MIRAGO S 25 TABLET?

A: MIRAGO S 25 TABLET is not recommended for use in patients having severe liver
or kidney diseases, severe stomach or bowel condition (ulcerative colitis),
myasthenia gravis or glaucoma. Therefore, consult your doctor for advice.

Q: How MIRAGO S 25 TABLET works in my body?

A: MIRAGO S 25 TABLET is a muscle relaxant which relaxes the smooth muscles
surrounding the bladder. This helps your bladder to hold more volume of urine
and controls urine flow. As a result, it reduces the activity of an overactive
bladder and enables you to wait longer before having to go to the bathroom.

Q: Can MIRAGO S 25 TABLET cause dry mouth?

A: MIRAGO S 25 TABLET may cause dry mouth in some individuals. To manage this,
drink plenty of water to keep yourself hydrated. However, inform your doctor if
this side effect troubles you.

Q: Can MIRAGO S 25 TABLET be used during pregnancy?

A: MIRAGO S 25 TABLET is not recommended for use in pregnant women unless
considered necessary by the physician. Therefore, consult your doctor before
taking it.

Q: What is the best time to take MIRAGO S 25 TABLET?

A: MIRAGO S 25 TABLET can be taken at any time of the day. However, consult your
doctor for advice.

Q: Can MIRAGO S 25 TABLET cause dizziness?

A: Yes. MIRAGO S 25 TABLET rarely causes dizziness in some individuals. If you
experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or
operating any tools or machines while you are feeling dizzy. Consult your doctor
if your dizziness worsens.

Q: How and when should I take MIRAGO S 25 TABLET?

A: Take MIRAGO S 25 TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. [GBNKEYEORD] can be
taken with or without food. Your doctor will decide the correct dose and
duration of therapy for you depending upon your age, body weight and disease
condition.

Q: Will MIRAGO S 25 TABLET affect fertility?

A: No. MIRAGO S 25 TABLET does not affect fertility. It only improves urinary
symptoms associated with overactive bladder by relaxing the smooth muscles
surrounding the bladder.

Q: How long will MIRAGO S 25 TABLET take to manage my disease?

A: It may take up to 4 weeks for MIRAGO S 25 TABLET to show the results.
However, this period varies from person to person based on their disease
condition. Consult your doctor if your symptoms are not relived even after
taking MIRAGO S 25 TABLET for a prolonged period.

Q: What to do if I forgot to take MIRAGO S 25 TABLET?

A: If you forgot to take a dose of MIRAGO S 25 TABLET take it as soon as you
remember. However, if it is time to take the next dose, skip the missed dose and
take the next dose at regular times. Do not take a double dose to compensate a
missed dose.

Q: Will taking a higher dose of MIRAGO S 25 TABLET be more effective?

A: No. Do not take a higher dose of MIRAGO S 25 TABLET than the prescribed one
without consulting your doctor. Taking a higher dose of MIRAGO S 25 TABLET may
not be beneficial. Instead, it can cause serious side effects. If the prescribed
dose is not effective for you, consult your doctor. Your doctor may prescribe a
suitable higher dose or suggest an alternative therapy after evaluating your
disease condition.

Useful Diagnostic Tests

• Prostate Specific Antigen-Psa (Total)
• Prostate Specific Antigen-Psa (Free)