RANEX M Tablet 10's

Introduction About RANEX M TABLET

RANEX M TABLET contains a combination of Mefenamic acid and Tranexamic acid,
which belongs to the group of medicines called Non-Steroidal Anti-inflammatory
Drugs (NSAIDs) and antifibrinolytics. It helps to stop/arrest bleeding and
relieve pain and swelling from various parts of the body. It is used to manage,
control and manage heavy menstrual bleeding (menorrhagia) and menstrual pain,
bleeding from the nose or eyes, following a tooth extraction, prostate surgery
etc.

Tranexamic acid works by managing the breakdown of blood clots by blocking the
interaction of plasminogen with fibrin. Mefenamic acid works by managing the
release of a chemical messenger called prostaglandin by inhibiting an enzyme
called cyclooxygenase that causes fever, pain and inflammation in the body
(redness and swelling). Your doctor may suggest you take relevant medical tests
to understand your existing condition.

RANEX M TABLET is not recommended for use if you have severe kidney disease or
failure, blood clots (thrombosis), abnormal body movements such as fits or
seizures, an abnormal or excessive bleeding disorder (consum
etc. RANEX M TABLET should be used with caution. Inform your doctor if you have
blood in the urine, uncontrolled bleeding, blood clots throughout your body,
irregular menstruation, mild to moderate kidney or liver disease, angioneurotic
oedema (HANO), etc.

RANEX M TABLET should be used with caution in pregnant women and nursing mothers
and only if prescribed by a doctor. The most common side effects of RANEX M
TABLET are feeling sick, vomiting, having a headache, having an abnormal
heartbeat, having changes in blood pressure, having difficulty urinating, having
urine leaks, etc. Contact your doctor if the symptoms worsen.

Uses Of RANEX M TABLET

• To manage, control and manage bleeding and pain in conditions such as heavy menstrual bleeding (Menorrhagia), Dysfunctional uterine bleeding (DUB), tooth removal, nose bleeds etc.

How RANEX M TABLET Works

Tranexamic acid works by managing the breakdown of blood clots by blocking the
interaction of plasminogen with fibrin. Mefenamic acid works by managing the
release of a chemical messenger called prostaglandin by inhibiting an enzyme
called cyclooxygenase that causes fever, pain and inflammation in the body
(redness and swelling). As a result, RANEX M TABLET management controls and
manages severe loss of blood and pain.

How to use RANEX M TABLET

Take RANEX M TABLET as advised by your physician. Swallow the medicine with a
glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose, frequency and duration for you depending on your age, body weight
and disease condition.

Side Effects Of RANEX M TABLET

Common

• feeling sick
• vomiting
• heartburn
• ingestion
• stomach pain or discomfort
• loose stools
• nose block
• tiredness
• muscle or joint pain
• pain or swelling of the sinus
• low red blood cells (anaemia)

Rare

Stop taking RANEX M TABLET and contact your doctor immediately if you experience
any of the following side effects:

• severe allergic reactions (such as skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue and/or throat with difficulty in breathing or swallowing).
• chest pain or heaviness in the chest
• difficulty in breathing
• coughing up blood
• fainting
• pain or swelling of the legs or arms
• impaired or blurring of vision
• bleeding in the eyes

How To Manage Side Effects

Nausea (feeling sick) or vomiting:

Take RANEX M TABLET with or just after meals. Stick to simple meals. Avoid
eating rich or spicy food.

Headache:

Take rest and get adequate sleep and stay hydrated. Consult your doctor
immediately if the symptoms persist or worsen.

Diarrhea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated.
Consult your doctor immediately if the symptom did not improve.

Warning & Precautions

!### Pregnancy

RANEX M TABLET should be used with caution in pregnant women, only if
recommended by your doctor. Consult your doctor before taking it.

!### Breastfeeding

RANEX M TABLET should be used with caution in breastfeeding mothers, only if
recommended by your doctor. Consult your doctor before taking it.

!### Driving and Using Machines

Do not drive or operate any heavy tools or machines. If you are experiencing
improper vision, dizziness etc.

!### Alcohol

Avoid consuming alcohol while using RANEX M TABLET, as it may worsen your
existing condition and increases the risk of bleeding in the stomach. Consult
your doctor before taking it.

!### Kidney

RANEX M TABLET is not recommended for use if are having severe kidney disease
such as kidney failure etc. Consult your doctor before taking it.

!### Liver

RANEX M TABLET should be used with caution if you are having liver disease.
Consult your doctor before taking it.

!### Allergy

Do not take RANEX M TABLET if you are allergic to Tranexamic acid and Mefenamic
acid.

Others

RANEX M TABLET is not recommended for use if you have:

• thrombosis – blood clot or blockage in blood vessels
• fits or seizure
• excessive bleeding disorder such as consum

Before taking RANEX M TABLET, inform your physician if you have:

• blood in the urine
• uncontrolled bleeding
• irregular menstrual period
• angioneurotic oedema (HANO)

Use in Pediatrics:

The safety of the usage of RANEX M TABLET in children is not known. Consult your
doctor for advice.

Use in Geriatrics:

RANEX M TABLET should be used with caution in an elderly patient. Consult your
doctor before taking this medicine.

Interactions

A. Drug-Drug interactions:

Before taking RANEX M TABLET, inform your doctor if you are taking any of the
following medicine.

• birth control medications such as desogestrel, estradiol, dienogest, drospirenone etc.
• streptokinase – used to break down blood clots.
• Ibuprofen, paracetamol, celecoxib – used to manage pain, fever and swelling

B. Drug - Food interaction:

The possible interaction of RANEX M TABLET with foods is not known. Consult your
doctor for advice.

Overdosage:

If you or anyone else accidentally take too much of RANEX M TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose are
feeling sick, vomiting, dizziness or lightheadedness, fits or seizure etc

Synopsis

Drug	:	Mefenamic acid, Tranexamic acid
Pharmacological Category	:	Non-steroidal Anti-inflammatory Drugs (NSAIDs), Anti-fibrinolytics
Therapeutic Indication	:	To manage, manage and control bleeding and relieve pain
Dosage Forms	:	Tablet, Capsule, Injection

More Information

• Keep out of reach of children
• Keep away from sunlight
• Store at room temperature

FAQs About RANEX M TABLET

Q: Can RANEX M TABLET be used for managing heavy menstrual bleeding?

A: Heavy menstrual bleeding is caused by several conditions, such as a fibroid
in the uterus, the unusual shape of the womb, the irregular or abnormal lining
of the uterus, a clotting disorder, etc. They present with bleeding and pain.
RANEX M TABLET helps to stop bleeding and relieve pain.

Q: Who is not recommended for using RANEX M TABLET?

A: RANEX M TABLET is not recommended for use in patients with active diseases
such as severe kidney disease, fits or seizures, excessive bleeding, blood clots
in blood vessels (thrombosis), etc.

Q: What to do if RANEX M TABLET is taken in excess

A: If you or anyone else accidentally takes too much RANEX M TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose are
feeling sick, vomiting, dizziness or light-headedness, stomach pain, etc.

Q: Is RANEX M TABLET safe to use in a kidney disease patient?

A: RANEX M TABLET should be used with caution if you have mild to moderate
kidney disease. It is not recommended for use if you have severe kidney disease,
such as kidney failure. Consult your doctor for advice.

Q: Is it safe to use RANEX M TABLET while taking birth control oral
contrace

A: The use of birth control medicine such as desogestrel, estradiol, dienogest,
drospirenone, etc. may interact when used with RANEX M TABLET, whichresults in
worsening side effects.

Useful Diagnostic Tests

• CBC
• Fasting Blood Sugar Test
• Glucose Tolerance Test
• Random Blood Sugar Test
• HBA1c
• KFT - Kidney function test
• LFT – Liver function test
• RFT – Renal function test
• ECG
• Cardiac ECHO
• Ultrasound
• Hysteroscopy test
• Biopsy
• Bleeding time and clotting time
• D-Dimer test
• ESR
• CRP