Nitrocontin 6.4mg Tablet 30'S

Introduction About NITROCONTIN 6.4MG TABLET

NITROCONTIN 6.4MG TABLET contains Nitroglycerin that belongs to the group of
medicines called Vasodilators. It is used for the management of angina pectoris
due to coronary artery disease. Angina is a type of chest pain which is caused
by reduced blood flow to the heart as a result of coronary artery disease.
Symptoms are feeling pressure, squeezing, heaviness, tightness or pain in the
chest or a heavy weight is lying on the chest.

Along with NITROCONTIN 6.4MG TABLET your doctor may advise you to make certain
lifestyle changes such as quitting alcohol and smoking, eating a healthy diet,
managing weight and improving your sleep pattern. NITROCONTIN 6.4MG TABLET is
not recommended for use in patients having heart diseases (hypertrophic
obstructive cardiomyopathy), anemia, raised pressure in the head, raised
pressure in the eye (glaucoma), or are taking medicines to manage erectile
dysfunction (sildenafil, vardenafil, tadalafil. NITROCONTIN 6.4MG TABLET should
be used with caution in patients having liver or kidney diseases, underactive
thyroid gland, low body temperature, malnourishment, abnormally low levels of
oxygen in blood, very low blood pressure, low blood volume, disease of the blood
vessels supplying the brain, or conditions that lower blood volume in the heart.

NITROCONTIN 6.4MG TABLET should be used with caution in pregnant and
breast-feeding women. Consult your doctor for advice. NITROCONTIN 6.4MG TABLET
is not recommended for use in children. NITROCONTIN 6.4MG TABLET should be used
with caution in elderly patients. The most common side effects of taking
NITROCONTIN 6.4MG TABLET are throbbing headache, spinning sensation, dizziness,
drowsiness, lack of energy. Consult your doctor if the symptoms worsen or
doesn’t improve.

Uses Of NITROCONTIN 6.4MG TABLET

• It is used for management of angina pectoris due to coronary artery disease

How NITROCONTIN 6.4MG TABLET Works

NITROCONTIN 6.4MG TABLET causes relaxation of smooth muscles within blood
vessels which leads to relaxation and widening of blood vessels. This improves
blood supply to the heart muscles. As a result, it helps to relieve chest pain
and blood pressure.

How to use NITROCONTIN 6.4MG TABLET

Always use NITROCONTIN 6.4MG TABLET exactly as prescribed by your doctor. For
Tablet, Capsule: Swallow NITROCONTIN 6.4MG TABLET with a glass of water. Do
not crush or chew the medicine. For Sublingual Tablet: Place NITROCONTIN
6.4MG TABLET inside your mouth, below the tongue and allow it to dissolve
completely. Do not swallow or chew the medicine. Your doctor will decide the
correct dose and duration of therapy for you depending on your age, body weight
and severity of the disease condition. Continue to take NITROCONTIN 6.4MG TABLET
for the stipulated duration prescribed by your doctor to achieve better results.

Side Effects Of NITROCONTIN 6.4MG TABLET

Common

• throbbing headache
• spinning sensation
• fall in blood pressure when seated or standing up
• dizziness
• drowsiness
• lack of energy

Uncommon

• fainting
• facial flushing
• nausea
• vomiting
• localised burning sensation
• tongue blistering

Rare

• restlessness
• heartburn
• bad breath, red, itchy, or flaky skin, skin rash

Stop taking NITROCONTIN 6.4MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• worsening of angina symptoms, chest pain
• signs of hypoxaemia (low levels of oxygen in the blood) (difficulty breathing, increased rate of breathing)
• signs of methemoglobinemia (breathing problems, tiredness, headache)
• difficulty breathing, bluish discolouration of the lips, fingers or toes (cyanosis)
• rapid or slowed heartbeat
• blindness in one eye
• cerebral ischaemia (impaired blood flow to the brain) which may cause weakness in one leg or arm or weakness in one entire side of the body
• difficulty speaking, slurred speech
• loss of coordination
• allergic skin reactions

How To Manage Side Effects

!### Dizziness Or Drowsiness

Lie, or sit down immediately when you feel dizzy. If you're feeling severe
episodes of spinning(vertigo), lie in a dark and quiet place with your eyes
closed. Try to avoid vehicle driving. Take your doctor’s advice if dizziness
doesn’t improve.

Headache

Try to take rest and do not involve yourself in exertive activities. Rest in a
quiet and dark room. Apply a pain-relieving balm on your forehead. Take your
doctor’s advice if the headache doesn’t improve.

!### Nausea And Vomiting

Take this medicine with or after meals. Stick to simple meals while taking this
medicine. Avoid eating rich or spicy food. Do not consume any medication by
yourself. Take your doctor’s advice if the nausea doesn’t improve or
worsen. Drink clear or ice-cold drinks. Eat bland, light foods and avoid fried,
oily, or sweet foods. Avoid carbonated drinks. Take your doctor’s advice if
vomiting doesn’t improve.

Warning & Precautions

!### Pregnancy

Use with CautionNITROCONTIN 6.4MG TABLET should be used with caution in pregnant women. Consult
your doctor before taking NITROCONTIN 6.4MG TABLET.

!### Breastfeeding

Use with CautionNITROCONTIN 6.4MG TABLET should be used with caution in breastfeeding women.
Consult your doctor before taking NITROCONTIN 6.4MG TABLET.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel dizzy after taking NITROCONTIN
6.4MG TABLET.

!### Alcohol

Consult your doctorAvoid consum
as it may increase some effects of the medicine.

!### Kidney

Use with CautionNITROCONTIN 6.4MG TABLET should be taken with caution in patients with severe
kidney disease. Consult your doctor before taking it.

!### Liver

Use with CautionNITROCONTIN 6.4MG TABLET should be used with caution in patients with severe
liver disease. Consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take NITROCONTIN 6.4MG TABLET if you are allergic to Nitroglycerin or any
other components of this medicine.

!### Heart Disease

Consult your doctorNITROCONTIN 6.4MG TABLET is not recommended for use in patients having heart
diseases such as hypertrophic obstructive cardiomyopathy (thickening of heart
muscles). NITROCONTIN 6.4MG TABLET should be used with caution in patients
having other heart diseases such as have had a recent heart attack, narrowing of
heart valves, inflammation of heart, heart failure or fluid build-up around the
heart. Consult your doctor before taking NITROCONTIN 6.4MG TABLET.

!### Use In Pediatrics

ContraindicatedNITROCONTIN 6.4MG TABLET is not recommended for use in children. Ask for the
advice of your child’s doctor before giving it to your child.

!### Use In Geriatrics

Use with CautionNITROCONTIN 6.4MG TABLET should be used with caution in elderly patients. Ask
for your doctor’s advice before taking the medicine.

Others

NITROCONTIN 6.4MG TABLET is not recommended for use if you:

• have anemia
• have raised pressure in head
• are bleeding on brain (pain in eyes, changes in vision, bad headache behind the eyes)
• have raised pressure in the eye

Before taking NITROCONTIN 6.4MG TABLET inform your doctor if you have:

• underactive thyroid gland
• low body temperature
• malnutrition (poor nutrition due to digestion problem or imbalanced diet)
• abnormally decreased levels of oxygen in the blood
• severely low blood pressure
• low blood volume
• conditions that lower the blood volume in the heart
• cerebrovascular diseases (diseases affecting the blood vessels supplying the brain)

Interactions

A. Drug-Drug interactions:

Before taking NITROCONTIN 6.4MG TABLET, inform your doctor if you are taking any
of the following medicine:

• medicines for erectile dysfunction (Ex. sildenafil, vardenafil, tadalafil)
• medicines used to manage paracetamol overdose (Ex. n-acetylcysteine)
• medicines for migraine (Ex. ergotamine)
• other nitrates used to manage heart diseases (Ex. isosorbide dinitrate, isosorbide mononitrate, disopyramide), high blood pressure (Ex. ramipril, atorvastatin)
• medicines used for thinning blood and manage blood clots (Ex. warfarin)
• medicines used to manage Parkinson’s disease (Ex. apomorphine)
• medicines used to manage stomach ulcers (Ex. propantheline)
• medicines used to manage anxiety and depression (Ex. amitriptyline, isocarboxazid)

Overdosage:

If you or anyone else uses too much of NITROCONTIN 6.4MG TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdosage of
NITROCONTIN 6.4MG TABLET may include nausea, low blood pressure, restlessness,
fainting, blue coloration of the skin, methaemoglobin in the blood, breathing
difficulties, lack of oxygen in tissues, slow heartbeat or mental illness.

Synopsis

Drug	:	Nitroglycerin (Glyceryl trinitrate)
Pharmacological Category	:	Vasodilators
Therapeutic Indication	:	Angina pectoris
Dosage Forms	:	Tablet, Capsule, Sublingual Tablet, Injection, Patch, Spray

More Information

Storage

• Keep NITROCONTIN 6.4MG TABLET out of reach in children
• Store NITROCONTIN 6.4MG TABLET at room temperature below 25°C

FAQs About NITROCONTIN 6.4MG TABLET

Q: Why is NITROCONTIN 6.4MG TABLET prescribed?

A: NITROCONTIN 6.4MG TABLET is used for management of angina pectoris due to
coronary artery disease. Angina is a type of chest pain which is caused by
reduced blood flow to the heart as a result of coronary artery disease. Symptoms
are feeling pressure, squeezing, heaviness, tightness or pain in the chest or a
heavy weight is lying on the chest.

Q: Can NITROCONTIN 6.4MG TABLET be used in elderly patients?

A: NITROCONTIN 6.4MG TABLET should be used with caution in elderly patients.
Take the medicines sat down to reduce possible low blood pressure or fainting.
Your doctor may change the dose to suit your condition. If you notice that
NITROCONTIN 6.4MG TABLET is not working as well at relieving pain as they have
done, contact your doctor.

Q: How to use NITROCONTIN 6.4MG TABLET?

A: Always use NITROCONTIN 6.4MG TABLET exactly as prescribed by your doctor. For
Tablet, Capsule: Swallow NITROCONTIN 6.4MG TABLET with a glass of water. Do not
crush or chew the medicine. For Sublingual Tablet: Place NITROCONTIN 6.4MG
TABLET inside your mouth, below the tongue and allow it to dissolve completely.
Do not swallow or chew the medicine.

Q: Can NITROCONTIN 6.4MG TABLET cause headache?

A: Yes. NITROCONTIN 6.4MG TABLET may cause throbbing headache. If it happens,
try to take rest and do not involve yourself in exertive activities. Rest in a
quiet and dark room. Apply a pain-relieving balm on your forehead. Do not
consume any medication without consulting a doctor. Take your doctor’s advice if
headache doesn’t improve.

Q: Is it safe to consume alcohol while being managed with NITROCONTIN 6.4MG TABLET?

A: You are advised not to drink alcohol with NITROCONTIN 6.4MG TABLET, as some
of the effects of this medicine are increased such as dizziness. If you have a
habit of drinking alcohol, take your doctor’s advice before taking NITROCONTIN
6.4MG TABLET.

Q: Can NITROCONTIN 6.4MG TABLET affect my ability to drive?

A: As NITROCONTIN 6.4MG TABLET may cause dizziness, you should make sure you are
not affected before driving or operating machinery, especially if taken with
alcohol. Do not drive or operate any machines if you feel dizzy after taking
NITROCONTIN 6.4MG TABLET. You can resume doing your activities after you feel
normal again.

Useful Diagnostic Tests

• ECG (electrocardiogram)
• Kidney Function Tests
• Liver Function Tests
• Chest Xray