Mirapex ER 1.5mg Tablet 10'S

Introduction About MIRAPEX ER 1.5MG TABLET

MIRAPEX ER 1.5MG TABLET contains Pramipexole which belongs to the group of
medicines called Dopamine agonists. It is used to manage signs and symptoms of
idiopathic Parkinson’s disease.

It is also prescribed to manage conditions such as Restless Legs Syndrome.

A disorder of the central nervous system that affects movement, often including
tremors. Nerve cell damage in the brain causes dopamine levels to drop, leading
to the symptoms of Parkinson's.

MIRAPEX ER 1.5MG TABLET should not be given in patients with kidney diseases and
psychosis. MIRAPEX ER 1.5MG TABLET is not recommended for use in pregnancy and
breastfeeding.

This medicine is strictly for use in adults and should not be used in children
and adolescents under 18 years of age.

The common side effects of taking MIRAPEX ER 1.5MG TABLET include sleepiness,
dizziness, dyskinesia, nausea, hallucinations (seeing, hearing or feeling things
that are not present), abnormal dreams, confusion, behavioural symptoms (Impulse
control and compulsions), headache, double or blurred vision, low blood
pressure, constipation, vomiting, swelling of body usually in the legs,
decreased weight and appetite. Consult your doctor for advice if any of the
above side effects worsen.

Uses Of MIRAPEX ER 1.5MG TABLET

• Used to manage signs and symptoms of idiopathic Parkinson’s disease

How MIRAPEX ER 1.5MG TABLET Works

MIRAPEX ER 1.5MG TABLET is a dopamine agonist which binds to a set of dopamine
receptors in the brain. It relieves Parkinsonism by stimulating dopamine
receptors present in the striatum (part of the brain that is responsible for
cognition, planning, decision-making, motivation, reinforcement, and reward
perce

How to use MIRAPEX ER 1.5MG TABLET

Take MIRAPEX ER 1.5MG TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your physician will
decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

Side Effects Of MIRAPEX ER 1.5MG TABLET

Common

• sleepiness
• dizziness
• uncontrolled, involuntary movement
• nausea
• abnormal dreams
• confusion
• headache
• double or blurred vision
• low blood pressure
• constipation
• vomiting
• swelling of body usually in the legs
• decreased weight and appetite
• fatigue
• insomnia

Uncommon

• paranoia
• delusion
• compulsive shopping, gambling, hypersexuality, delusion, loss of libido, delirium, paranoia, binge eating
• amnesia (loss of memory)
• loss of consciousness
• cardiac failure
• dyspnoea
• hiccups
• rash, itching
• difficulties in breathing
• hyperkinesia (inability to remain still)
• restlessness
• loss of reality (delirium)

Rare

• m

Stop takingMIRAPEX ER 1.5MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• serious allergic reaction such as sudden wheezing, rash, itching, hives, swelling of the lips, tongue, face or throat causing difficulty in swallowing or breathing
• symptoms of Pneumonia (infection of the lungs) include fever, shivering, sweating, difficulty breathing, chest pain and feeling unwell
• symptoms of heart failure, causing shortness of breath or a persistent cough, extreme tiredness and swelling of the ankles
• decreased sodium levels in the blood, which may cause weakness, confusion muscle pains
• falling asleep while you are doing activities such as talking, eating, driving, or feel sleepier than normal
• hallucinations or other psychotic-like behaviour (seeing visions, hearing sounds or feeling sensations that are not real, confusion, excessive suspicion, aggressive behaviour, agitation, delusional beliefs and disorg
• withdrawal symptoms such as fever, confusion, severe muscle stiffness, apathy, anxiety, depression, fatigue, difficulty sleeping, sweating, and pain

How To Manage Side Effects

Nausea:

Take MIRAPEX ER 1.5MG TABLET during or after meals to minimise effects. Consult
your doctor for advice.

Constipation:

Eat fibre rich food, drink plenty of fluids to avoid constipation. Consult your
doctor for advice.

Warning & Precautions

Pregnancy

Use of MIRAPEX ER 1.5MG TABLET is not recommended in pregnant women. Contact
your doctor before taking.

Breastfeeding

MIRAPEX ER 1.5MG TABLET is not recommended for use in breastfeeding women as it
may pass through the breast milk. Contact your doctor before taking.

!### Driving and Using Machines

Use of MIRAPEX ER 1.5MG TABLET can cause sleepiness, drowsiness, hallucinations
and sudden onset of sleep. Hence, it is not recommended to drive or use machines
after taking this medicine.

Alcohol

Avoid alcohol consum
increase the risk of sleepiness.

!### Kidney

MIRAPEX ER 1.5MG TABLET should be used with caution in patients with kidneys
disease. Contact your doctor before taking.

!### Liver

MIRAPEX ER 1.5MG TABLET should be used with caution in patients with liver
diseases. Contact your doctor before taking.

!### Allergy

Do not take MIRAPEX ER 1.5MG TABLET if you are allergic to Pramipexole or to
other ingredients of the medicine.

!### Lungs

MIRAPEX ER 1.5MG TABLET should be used with caution in patients with existing
pulmonary diseases. Contact your doctor before taking.

!### Heart Disease

MIRAPEX ER 1.5MG TABLET should be used with caution in patients with severe
heart and blood vessel disease. Contact your doctor before taking.

Others

MIRAPEX ER 1.5MG TABLET is not recommended for use if you have:

• psychosis (schizophrenia)

Use in pediatrics:

Use of MIRAPEX ER 1.5MG TABLET is not advisable in children and adolescents
under 18 years of age. Contact your doctor before taking.

Use in geriatrics:

MIRAPEX ER 1.5MG TABLET should be used with caution in elderly patients over 65
years of age. Contact your doctor to get the correct dose.

Interactions

A. Drug-Drug Interactions:

Before taking MIRAPEX ER 1.5MG TABLET, inform your doctor if you are taking any
of the following medicine:

• cimetidine, r
• amantadine, levodopa, benztropine (medicines used to manage parkinson’s disease)
• mexiletine, procainamide, quinidine (medicines used to manage irregular heartbeats
• zidovudine (medicine used to manage HIV infection)
• cisplatin (medicine used to manage various types of cancers)
• quinine (medicines used to manage malaria)
• any medicines that calm you down (sedative effect)
• phenothiazines, butyrophenones, thioxanthenes (medicines used to manage schizophrenia and psychoses)
• metoclopramide (medicines used to manage nausea and vomiting)
• diltiazem, triamterene, verapamil, hydrochlorothiazide (medicines used to manage high blood pressure and heart diseases)
• cefadroxil, cefaclor, amoxicillin (medicines used for bacterial infections)
• indomethacin (medicines used to manage pain)
• chlorpropamide (medicines used to manage diabetes mellitus)

Overdosage:

If you miss a dose of MIRAPEX ER 1.5MG TABLET, do not take double dose. If you
have accidentally taken too much of this medicine, contact your doctor or
nearest hospital immediately for advice. Symptoms of overdosage are vomiting,
nausea, agitation, low blood pressure, hallucination, restlessness, confusion.

Synopsis

Drug	:	Pramipexol
Pharmacological Category	:	Dopamine agonists
Therapeutic Indication	:	Idiopathic Parkinson’s disease
Dosage Forms	:	Tablet

More Information

• Keep MIRAPEX ER 1.5MG TABLET out of sight and reach of children
• Store MIRAPEX ER 1.5MG TABLET at room temperature

FAQs About MIRAPEX ER 1.5MG TABLET

What is the most important information I should know about MIRAPEX ER 1.5MG
TABLET?

MIRAPEX ER 1.5MG TABLET may cause you to fall asleep while you are doing daily
activities such as driving, talking with other people, watching TV, or eating.
Do not drive a car, operate a machine, or do anything that needs you to be alert
until you know how MIRAPEX ER 1.5MG TABLET affects you. Tell your doctor if this
happens.

When is MIRAPEX ER 1.5MG TABLET used?

MIRAPEX ER 1.5MG TABLET is used to manage Parkinson’s Disease and Restless Legs
Syndrome. Contact your doctor before taking.

Who should not take MIRAPEX ER 1.5MG TABLET?

Do not take MIRAPEX ER 1.5MG TABLET if you are allergic to Pramipexole or its
constituents.

What should I tell my doctor before taking MIRAPEX ER 1.5MG TABLET?

Tell your doctor about all of your medical conditions including kidney problems,
liver and heart problems or any other medical conditions.

How should I take MIRAPEX ER 1.5MG TABLET?

Take MIRAPEX ER 1.5MG TABLET as advised by your physician. Swallow the medicines
with a glass of water. Do not crush or chew the medicine. Your physician will
decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

What should I do if I miss a dose of MIRAPEX ER 1.5MG TABLET?

If you missed a dose, do not double the dose. Skip the missed dose and take your
next dose at regular interval. Be sure to tell your doctor right away if you
stop taking MIRAPEX ER 1.5MG TABLET for any reason. Do not start taking this
medicine again before speaking with your doctor.

What are the possible side effects of taking MIRAPEX ER 1.5MG TABLET?

MIRAPEX ER 1.5MG TABLET can cause side effects such ad dizziness, nausea,
falling asleep during normal daily activities, hallucinations, low blood
pressure, fainting, or sweating. Contact your physician if any of the symptoms
worsen.