Microcid SR 75mg Capsule 10'S

Introduction About MICROCID SR 75MG CAPSULE

MICROCID SR 75MG CAPSULE contains Indomethacin, which belongs to the group of
medicines called Non-Steroidal Anti-Inflammatory Drugs. It is used to reduce
swelling and manage moderate to severe inflammatory diseases of the joints (such
as rheumatoid arthritis, osteoarthritis and degenerative hip disease), pain &
stiffness in the backbone (ankylosing spondylitis).

It also manages sprains & strains, post-operative pain, lower back pain, pain
due to periods, gout (joint pain), and acute painful shoulder (such as bursitis,
tendinitis). During management with MICROCID SR 75MG CAPSULE, your doctor might
advise you to take certain tests.

MICROCID SR 75MG CAPSULE is not recommended for use in patients with
angioneurotic oedema (condition marked by swelling of the face, lips, tongue, or
throat), have or had signs of pe
(black tarry stools), nasal obstruction (due to nasal polyps), severe liver,
kidney, or heart problems.

Before taking MICROCID SR 75MG CAPSULE inform your doctor if you have a history
of high blood pressure or congestive heart failure, bleeding or blood clotting
disorder, mental health problem, epilepsy, Parkinson’s Disease (tremor,
stiffness and shuffling) or severe infection.

Also inform your doctor if you have fluid retention which may be caused by
diseases of the heart or kidneys, history of asthma, gastrointestinal diseases
(ulcerative colitis or Crohn’s disease), systemic lupus erythematosus (SLE),
diabetes, problem with the circulation in the legs, decreased amount of fluid in
body or are going to have surgery.

Avoid consum
MICROCID SR 75MG CAPSULE is not recommended for use in pregnant women
(especially during the last 3 months of pregnancy) and in breastfeeding women.

This medicine is not recommended for use in children aged below 14 years. It
should be used with caution in elderly patients. The most common side effect of
taking MICROCID SR 75MG CAPSULE is a mild headache. Contact your doctor if the
symptoms worsen.

Uses Of MICROCID SR 75MG CAPSULE

It is used to reduce swelling and manage:

• moderate to severe inflammatory diseases of the joints (such as rheumatoid arthritis, osteoarthritis and degenerative hip disease)
• pain & stiffness in the backbone (ankylosing spondylitis)
• sprains & strains (such as acute muscle and bone disorders)
• lower back pain
• pain & swelling following muscle/ bone surgery
• pain due to menstruation
• gout (joint pain)
• acute painful shoulder (such as bursitis, tendinitis)

How MICROCID SR 75MG CAPSULE Works

MICROCID SR 75MG CAPSULE works by managing the function of enzyme
cyclooxygenase-1 and 2 which leads to the stopping of prostaglandins synthesis
(chemical substances responsible for pain & inflammation) that results in
reduced inflammatory reactions and relief from pain.

How to use MICROCID SR 75MG CAPSULE

Take MICROCID SR 75MG CAPSULE as advised by your physician. Swallow MICROCID SR
75MG CAPSULE with a glass of water/milk, with or immediately after food. Do not
crush or chew the medicine. Your doctor will decide the correct dose and
duration for you depending on your age, body weight, and disease condition.

Side Effects Of MICROCID SR 75MG CAPSULE

Common

• mild headache

Uncommon

• ringing or buzzing or other unexplained noise in the ears
• difficulty having a bowel movement
• discouragement, feeling sad or empty
• general feeling of discomfort or illness
• hearing loss
• irritability
• loss of interest or pleasure
• sleepiness, trouble concentrating

Rare

• anxiety
• bloated or full feeling
• excess air or gas in the stomach or intestines
• feeling of constant movement of self or surroundings
• involuntary muscle movements
• light-headedness
• sensation of spinning
• tiredness
• trouble sleeping
• trouble with speaking

Stop taking MICROCID SR 75MG CAPSULE and contact your doctor immediately if you
experience any of the following side effects:

• signs of bleeding in the stomach such as blood in feces, blood vomit or dark particles that look like coffee grounds
• signs of an allergic reaction such as difficulty breathing/swallowing, asthma, sudden decrease in blood pressure, swelling of the face, lips, tongue, or throat
• indigestion/heartburn
• abdominal pain or other abnormal symptoms such as vomit, nausea, constipation, diarrhoea, inflammation of the stomach lining, small intestine or mouth, perforation of previous intestinal damage, blockage in the intestine
• signs of abnormal liver function/liver disease such as jaundice, inflammation of the liver causing weakness, loss of appetite, weight loss, abdominal pain, fever
• serious skin reactions such as itching, pale or red irregular raised patches with severe itching (hives), blood spots, bruising and discolouration of the skin, blisters/red skin, peeling and swelling of the skin that resembles severe burns, erythema multiforme (circular, irregular red patches on the skin of the hands and arms), Stevens-Johnson syndrome (a severe form of skin rash with flushing, fever, blisters or ulcers),
• ase

How To Manage Side Effects

Headache:

Apply a hot or cold-water bag on your head. Try to rest in a quiet and dark
room. Massage on the scalp or head with mild pressure. Consult your doctor if
symptoms do not improve.

Warning & Precautions

!### Pregnancy

MICROCID SR 75MG CAPSULE is not recommended for use during the last three months
of pregnancy.

It can be used with caution during the first six months of pregnancy if
recommended by your doctor.

!### Breastfeeding

MICROCID SR 75MG CAPSULE is not recommended for use in breastfeeding women.
Consult your doctor before taking MICROCID SR 75MG CAPSULE.

!### Driving and Using Machines

Do not drive or operate any machines while taking MICROCID SR 75MG CAPSULE as it
may cause drowsiness, dizziness, tiredness or vision problems. Consult your
doctor before taking MICROCID SR 75MG CAPSULE.

!### Alcohol

Avoid consum
increase the risk of ulcers and bleeding in the stomach.

!### Kidney

MICROCID SR 75MG CAPSULE is not recommended for use in patients with severe
kidney problems or advanced renal disease.

MICROCID SR 75MG CAPSULE should be used with caution in patients with renal
impairment. Consult your doctor before taking MICROCID SR 75MG CAPSULE.

!### Liver

MICROCID SR 75MG CAPSULE is not recommended for use in patients with severe
liver problems. MICROCID SR 75MG CAPSULE should be used with caution in patients
with hepatic impairment. Consult your doctor before taking MICROCID SR 75MG
CAPSULE.

!### Allergy

Do not take MICROCID SR 75MG CAPSULE if you are allergic to Indomethacin or any
other ingredient of this medicine, or other NSAIDS such as aspirin, ibuprofen.
Consult your doctor before taking MICROCID SR 75MG CAPSULE.

!### Lungs

MICROCID SR 75MG CAPSULE should be used with caution in patients with lung
problems such as asthma. Consult your doctor before taking MICROCID SR 75MG
CAPSULE.

!### Heart Disease

MICROCID SR 75MG CAPSULE is not recommended for use in patients with severe
heart problems. MICROCID SR 75MG CAPSULE should be used with caution in patients
with heart problems such as high blood pressure, congestive heart failure.
Consult your doctor for advice.

Others

MICROCID SR 75MG CAPSULE is not recommended for use if you:

• are suffering from angioneurotic oedema (a condition marked by swelling of the face, lips, tongue, or throat)
• have or had signs of pe
• have nasal obstruction due to nasal polyps

Before taking MICROCID SR 75MG CAPSULE, inform your doctor if you:

• are undergoing investigation for infertility
• have a history of high blood pressure
• have mental health problems
• have signs of Parkinson’s disease, such as tremor, stiffness, and rigidity
• have an infection or sepsis (severe infection)
• have or had a history of gastrointestinal diseases such as ulcerative colitis or Crohn’s disease
• have systemic lupus erythematosus (an allergic skin reaction) or other connective tissue disorders
• have diabetes
• have signs of extracellular volume depletion (reduced amount of fluid around the cells of the body) such as fatigue, confusion, muscle cramps, chest pain
• have peripheral arterial disease (problem with blood circulation in the legs)
• have a history of stomach ulcers
• have high cholesterol
• are a smoker
• are planning to undergo surgery
• have epilepsy
• have bleeding or blood clotting disorder

Use in pediatrics:

MICROCID SR 75MG CAPSULE is not recommended for use in children and adolescents
below 14 years of age. Consult your doctor before taking MICROCID SR 75MG
CAPSULE.

Use in geriatrics:

MICROCID SR 75MG CAPSULE should be taken with caution in elderly patients due to
the increased risk of side effects. The dose will be adjusted by your doctor.
Consult your doctor before taking MICROCID SR 75MG CAPSULE.

Interactions

A. Drug - Drug interactions:

Before taking MICROCID SR 75MG CAPSULE, inform your doctor if you are taking any
of the following medicines:

• other non-steroidal anti-inflammatory drugs (medicines used to reduce inflammation and relieve pain) Ex. aspirin, naproxen, celecoxib, diflunisal, methotrexate
• quinolone antibiotics (medicine used to manage infections Ex. ciprofloxacin)
• medicines used for blood thinning or manage blood clotting (Ex. warfarin, clopidogrel)
• medicines used to manage depression, such as selective serotonin reuptake inhibitors (Ex. fluoxetine), haloperidol, lithium (a medicine used to manage mental illness)
• medicines used to manage diabetes (Ex. metformin, gliclazide)
• phenytoin (medicine used to manage epilepsy)
• diazepam (a medicine used to manage anxiety, alcohol withdrawal, seizures and muscle spasm)
• medicines used to manage high blood pressure such as alpha-blockers (Ex. prazosin), beta blockers (Ex. atenolol), ACE inhibitors (Ex. lisinopril), angiotensin II receptor antagonists (Ex. valsartan), hydralazine or nifedipine, diuretics (Ex. triamterene, furosemide), thiazides (Ex. bendroflumethiazide), cardiac glycosides (used to manage heart failure, Ex. digoxin)
• medicines used to manage HIV infection (Ex. zalcitabine, zidovudine or ritonavir)
• medicines used to suppress the immune system and manage graft rejection (Ex. ciclosporin, tacrolimus or muromonab-CD3)
• antacids (medicines used to manage stomach acid and heartburn, Ex. aluminium hydroxide, magnesium hydroxide)
• corticosteroids (used to manage various allergic and inflammatory disorders, Ex. prednisolone)
• methotrexate or cyclophosphamide (medicines used to manage rheumatoid arthritis and certain types of cancer)
• desmopressin (medicine used to manage diabetes insipidus and urinary incontinence)
• mifepristone (a medicine used to terminate pregnancy)
• baclofen (a medicine used as a muscle relaxant)
• pentoxifylline (used to manage blood vessel disease and leg ulcers)
• probenecid (a medicine used to manage gout)
• tiludronic acid (a medicine used to manage Paget’s disease of bone)

Overdosage:

If you or anyone else has accidentally taken too much of MICROCID SR 75MG
CAPSULE, consult your doctor immediately or visit the nearby hospital. Signs and
symptoms of overdose may include headache, nausea, vomiting, stomach pain,
bleeding in the stomach/intestines, diarrhoea, disorientation, excitement, coma,
drowsiness, dizziness, ringing/buzzing in the ears, fainting, fits/seizures,
acute kidney/renal failure, liver damage.

Synopsis

Drug	:	Indomethacin
Pharmacological Category	:	Non-Steroidal Anti-Inflammatory Drugs
Therapeutic Indication	:	Inflammatory disease of the bone and joints
Dosage Forms	:	Tablet, Capsule, Injection, gel, suppository

More Information

• Keep out of reach of children
• Store in a dry place below 25°C

FAQs About MICROCID SR 75MG CAPSULE

Can MICROCID SR 75MG CAPSULE be used for back pain?

Yes. MICROCID SR 75MG CAPSULE can be used to relieve pain from the lower back
area, degenerative hip disease, ankylosing spondylitis, or sprains and strains.
Correct dose will be prescribed by your doctor depending on your age, body
weight and disease condition.

Can MICROCID SR 75MG CAPSULE increase blood pressure?

Yes, MICROCID SR 75MG CAPSULE increases blood pressure in hypertensive patients.
So taking medicines which decrease blood pressure along with MICROCID SR 75MG
CAPSULE might not serve the purpose. Consult your doctor for advice.

How does MICROCID SR 75MG CAPSULE work?

MICROCID SR 75MG CAPSULE works by managing the function of enzyme
cyclooxygenase-1 and 2 which leads to the stopping of prostaglandins synthesis
(chemical substances responsible for pain & inflammation) that results in
reduced inflammatory reactions and relief from pain.

Can MICROCID SR 75MG CAPSULE be used in pregnancy?

MICROCID SR 75MG CAPSULE is not recommended for use during the last three months
of pregnancy. It can be used with caution during the first six months of
pregnancy if recommended by your doctor.

Can MICROCID SR 75MG CAPSULE cause dizziness?

Yes, do not drive or operate any machines while taking MICROCID SR 75MG CAPSULE
as it may cause drowsiness, dizziness, tiredness, or vision problems. Consult
your doctor before taking MICROCID SR 75MG CAPSULE.

Useful Diagnostic Tests

• MRI
• X-Ray
• Uric Acid Test
• Eye tests
• Kidney and liver function tests