Piroxitas DT 20mg Tablet 10'S

Introduction About PIROXITAS DT 20MG TABLET

PIROXITAS DT 20MG TABLET contains Piroxicam, which belongs to the group of
medicines called Non-Steroidal Anti-Inflammatory Drugs. It helps to reduce pain
and swelling affecting the joints. It is also used to relieve the symptoms
caused by osteoarthritis (a joint disease that occurs when the protective
tissues at the end of the bones wear out and is characterised by joint pain in
the hands, neck, and hip), rheumatoid arthritis (autoimmune disease-causing
painful swelling of joints and stiffness), and ankylosing spondylitis
(rheumatism of the spine resulting in a hunched forward posture).

PIROXITAS DT 20MG TABLET is not recommended for use in patients with heart
problems, and it should be used with caution in patients with asthma, liver, and
kidney problems. PIROXITAS DT 20MG TABLET is not recommended for use in pregnant
women, especially during the last three months of pregnancy, and it should be
used with caution during breastfeeding.

The safety and effectiveness of PIROXITAS DT 20MG TABLET in children and
adolescents have not been established. PIROXITAS DT 20MG TABLET is not
recommended for use in elderly patients of 80 years and above. The most common
side effects of this medicine are nausea (feeling sick), vomiting, indigestion,
stomach pain, skin rash, headache, and drowsiness. Consult your physician if any
of the symptoms worsen.

Uses Of PIROXITAS DT 20MG TABLET

• Reduces pain and swelling affecting the joints
• Relieves the symptoms caused by osteoarthritis (joint disease), rheumatoid arthritis, and ankylosing spondylitis (rheumatism of the spine) such as swelling, stiffness and joint pain

How PIROXITAS DT 20MG TABLET Works

PIROXITAS DT 20MG TABLET exerts its anti-inflammatory actions by inhibiting the
enzyme cyclooxygenase-1 thereby, blocking the release of prostaglandins (a
substance produced during injury and inflammation causing pain and swelling) and
other chemical mediators that cause pain and swelling.

How to use PIROXITAS DT 20MG TABLET

Always take PIROXITAS DT 20MG TABLET as directed by your physician. Swallow the
medicine as a whole with a sip of water. Do not crush or chew them. The correct
dose and duration will be decided by your doctor depending on your age, and
health condition.

Side Effects Of PIROXITAS DT 20MG TABLET

Common

• dizziness or drowsiness
• nausea (feeling sick), vomiting
• diarrhea, indigestion
• abdomen pain or discomfort
• changes in the red blood cells which may cause unusual bruising or bleeding
• changes in white blood cell count which may lead to a high risk of infections
• anorexia (eating disorder or inability to eat)
• increase in blood sugar levels
• headache
• vertigo (feeling of spinning)
• ringing in ears (tinnitus)
• constipation
• wind
• itching, skin rash
• swelling of the feet, hands, or other parts of the body (oedema)
• weight gain

Uncommon

• blurred vision
• fast heartbeat
• sore mouth or lips
• low blood sugar level

Rare

• signs of kidney problems such as loss of appetite, decreased urinary output, fatigue
• change in urine output or appearance

Stop taking PIROXITAS DT 20MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• signs of an allergic reaction like asthma or worsening of asthma, irregular raised patches with severe itching (hives), swelling of the face, lips, throat or tongue, blood vessel inflammation, serum sickness (rash, fever, joint pain, enlarged lymph nodes), purple spots on the skin, joint pain, abdominal pain and kidney dysfunction (Henoch-Schoenlein purpura), narrowing of the airways causing difficulty in breathing/wheezing, rash
• signs of skin reactions such as severe rash involving reddening, a severe form of skin rash with flushing, fever, blisters, or ulcers (Stevens-Johnson syndrome), peeling and swelling of the skin as like in severe burns (toxic epidermal necrolysis)
• stomach or intestinal bleeding, ulceration, or perforation, vomit blood or dark particles that look like coffee grounds, blood in faeces (stools/motions), passing black tarry stools
• signs of liver disease include fatigue, weakness, loss of appetite, weight loss, abdominal pain, fever), yellowing of the skin or whites of the eyes (jaundice), inflammation of the liver (hepatitis)
• signs of kidney problems such as loss of appetite, decreased urinary output, fatigue
• signs of heart problems like water retention, high blood pressure, heart failure, increased risk of heart attack (“myocardial infarction”) or stroke
• indigestion or heartburn, abdominal pain, or other abnormal stomach symptoms
• signs of inflamed pancreas like severe pain in the upper abdomen or back
• hallucinations (hearing or seeing things that weren’t there really)

How To Manage Side Effects

Nausea or vomiting:

Take this medicine with meals or just after meals. Stick to simple meals. Try to
avoid oil-rich or spicy foods, sugary snacks, and drinks. Try to drink liquids
slowly along with your meals or in between meals. Consult your doctor if your
symptom is not improving.

Dizziness:

Lie or sit down immediately when you feel dizzy. If you're feeling severe
episodes of spinning (vertigo), lie in a dark and quiet place with your eyes
closed. Try to avoid vehicle driving. Discuss it with your doctor if the symptom
worsens.

Headache:

Apply a hot or cold water bag to your head. Try to take a rest in a quiet, dark
room. Drink tea or coffee. Massage the scalp or head with mild pressure. Consult
your doctor for advice.

Stomach pain:

Try to rest and relax. Try to have smaller and more frequent meals. Keep a
heating pad on your stomach. Take your physician’s advice.

Skin rash:

Try to avoid hot showers because they may cause skin irritation. Avoid frequent
contact with and rubbing over the affected area. Use sunscreen and protective
clothing when outdoors. If this symptom does not get better, speak to a doctor.

Warning & Precautions

!### Pregnancy

PIROXITAS DT 20MG TABLET is not recommended for use in pregnant women,
especially during the last three months of pregnancy. Consult your doctor before
taking it.

!### Breastfeeding

PIROXITAS DT 20MG TABLET should be used with caution in breastfeeding women
unless necessary. Consult with your physician.

!### Driving and Using Machines

Do not drive or operate any machinery while taking PIROXITAS DT 20MG TABLET as
it may make you feel dizzy, drowsy, have vision problems, and be tired. Consult
your physician.

!### Kidney

PIROXITAS DT 20MG TABLET should be taken with caution in patients with kidney
disease. Consult your doctor for advice.

!### Liver

PIROXITAS DT 20MG TABLET should be taken with caution in patients with liver
disease. Consult your doctor for advice.

!### Allergy

Do not take PIROXITAS DT 20MG TABLET if you are allergic to Piroxicam.

!### Lungs

PIROXITAS DT 20MG TABLET should be taken with caution in patients with asthma.
Consult your doctor for advice.

!### Heart Disease

PIROXITAS DT 20MG TABLET is not recommended for use in patients with severe
heart failure. It should be used with caution in patients with high blood
pressure and other heart problems. Consult your doctor for advice.

Others

PIROXITAS DT 20MG TABLET is not recommended for use if you:

• have a stomach or intestinal ulcer, bleeding, or perforation
• have stomach or intestines disorders such as ulcerative colitis, Crohn’s disease, gastrointestinal cancers or diverticulitis (inflamed or infected pouches/pockets in the colon)

Before taking PIROXITAS DT 20MG TABLET, inform your doctor if you:

• have stroke
• have high cholesterol or hardening of the blood vessels (arteries)
• have diabetes

Use in pediatrics:

The safety and effectiveness of PIROXITAS DT 20MG TABLET in children and
adolescents have not been established. Consult your doctor for advice.

Use in geriatrics:

PIROXITAS DT 20MG TABLET is not recommended for use in elderly patients of
80years and above. Consult your doctor for advice.

Interactions

A.Drug-Drug interactions:

• aspirin or other non-steroidal anti-inflammatory drugs for pain relief
• anticoagulants such as warfarin (a medicine used to manage blood clots)
• corticosteroids like prednisolone (medicines used to manage a variety of conditions such as allergies and hormone imbalance)
• low dose aspirin (75 mg) (a medicine used to manage heart attack or stroke)
• medicines used to manage heart problems (Ex. cardiac glycosides, such as digoxin)
• lithium or selective serotonin reuptake inhibitors (SSRIs) (medicines for depression)
• antihypertensives like telmisartan, and enalapril to manage high blood pressure
• methotrexate (a medicine used in the management of cancer, psoriasis and rheumatoid arthritis)
• ciclosporin, tacrolimus, (medicines to manage rejection of transplanted organs)
• quinolone antibiotics (Ex. ciprofloxacin) which are used to manage various infections
• mifepristone (a medicine used to terminate pregnancy)
• diuretics such as hydrochlorothiazide (used to manage high blood pressure or kidney problems)

Overdosage:

If you or anyone else accidentally take too much of PIROXITAS DT 20MG TABLET,
consult your doctor immediately or visit the nearby hospital. Signs and symptoms
of overdose include lethargy, nausea (feeling sick), vomiting, drowsiness, and
epigastric pain.

Synopsis

Drug	:	Piroxicam
Pharmacological Category	:	Non-steroidal anti-inflammatory drugs
Therapeutic Indication	:	Joint pain
Dosage Forms	:	Tablet, Capsule, Dispersible tablet, Gel, Injection

More Information

• Keep out of reach of children
• Store at a temperature below 25°C

FAQs About PIROXITAS DT 20MG TABLET

What are the uses of PIROXITAS DT 20MG TABLET?

PIROXITAS DT 20MG TABLET helps to reduce pain and swelling affecting the joints.
It is also used to relieve the symptoms caused by osteoarthritis (joint
disease), rheumatoid arthritis, and ankylosing spondylitis (rheumatism of the
spine), such as swelling, stiffness, and joint pain.

How does PIROXITAS DT 20MG TABLET work?

PIROXITAS DT 20MG TABLET exerts its anti-inflammatory actions by inhibiting the
enzyme cyclooxygenase-1, thereby blocking the release of prostaglandins (a
substance produced during injury and inflammation that causes pain and swelling)
and other chemical mediators that cause pain and swelling.

Can PIROXITAS DT 20MG TABLET be used in patients with heart problems?

PIROXITAS DT 20MG TABLET is not recommended for use in severe heart failure. It
should be used with caution in patients with high blood pressure and other heart
problems. Consult your doctor for advice.

Can PIROXITAS DT 20MG TABLET be used by a pregnant woman?

PIROXITAS DT 20MG TABLET is not recommended for use in pregnant women,
especially during the last three months of pregnancy. Consult your doctor for
advice before taking [GBNKEYEORD].

Does PIROXITAS DT 20MG TABLET cause nausea or vomiting?

Yes, it may cause nausea or vomiting in some patients. Take this medicine with
meals or just after meals. Stick to simple meals. Try to avoid oil-rich or spicy
foods, sugary snacks, and drinks. Try to drink liquids slowly along with your
meals or in between meals. Consult your doctor if your symptom is not improving.