LCD 250 CR Tablet 10's

Introduction About LCD 250 CR TABLET

LCD 250 CR TABLET is a combination of Carbidopa and Levodopa which belongs to
the group of medicines called Antiparkinsonian drugs. It is used to improve the
signs of Parkinsonism. Parkinsonism is a long-term illness caused due to loss of
nerve cells in the part of the brain which is responsible for producing
dopamine. Dopamine is a chemical messenger that controls body balance and
movements.

Symptoms of parkinsonism include slow and unsteady movements, muscle tightness,
shaking or trembling, difficulty in walking, balance and coordination.

LCD 250 CR TABLET must be used with caution among patients having any form of
glaucoma (increased pressure in the eyes), as it can lead to further damage to
the eye. LCD 250 CR TABLET is not recommended for use in women who are pregnant
or breastfeeding, including children and adolescents (aged below 18 years).

It is important for caregivers to notice and report doctor immediately that if
the patient develops any addictive symptoms like craving for large doses of LCD
250 CR TABLET, unusual behavior, gambling, excessive eating or spending, an
abnormally high sex drive or any other activities that could harm themselves or
others.

Try to avoid eating a heavy meal that includes a lot of protein (such as beef,
pork, cheese, fish and eggs) while taking LCD 250 CR TABLET, as it may interfere
with its absor

The common side effects of taking LCD 250 CR TABLET are nausea, vomiting,
abnormal muscle movements, loss of appetite, dry mouth, bitter taste and
tiredness. Consult your doctor if any of the side effects worsen.

Uses Of LCD 250 CR TABLET

• Used to improve the signs of Parkinsonism

How LCD 250 CR TABLET Works

LCD 250 CR TABLET effectively controls the signs of parkinsonism, where levodopa
acts by converting itself into a substance called dopamine (a chemical messenger
that controls body movement) and carbidopa acts by managing the breakdown of
levodopa outside the brain, thereby allowing greater proportion of levodopa to
enter the brain. Collectively they supplement the brain with sufficient dopamine
levels which ultimately results in improving the signs of parkinsonism.

How to use LCD 250 CR TABLET

Take LCD 250 CR TABLET as advised by your physician. Swallow the medicine as a
whole and do not crush or chew the medicine. Continue to take LCD 250 CR TABLET
unless your doctor tells you to stop because sudden withdrawal of LCD 250 CR
TABLET can cause symptoms like mental changes, fever and muscle tightness.

Your doctor will decide the correct dose and duration of LCD 250 CR TABLET for
you depending upon your age, body weight and disease condition.

Side Effects Of LCD 250 CR TABLET

Common

• abnormal body movements (dyskinesia, chorea, dystonia)
• nausea, vomiting, dry mouth, bitter taste
• loss of appetite
• low blood pressure while standing up from sitting or lying position (orthostatic hypotension), fainting
• confusion, dizziness, nightmares, drowsiness, tiredness, sleeplessness
• feeling euphoria (an extremely strong feeling of happiness)

Uncommon

• weight loss or weight gain
• difficulty in speaking or making abnormal sounds while speaking
• hoarseness, chest pain
• constipation, diarrhea, bloating
• increased saliva secretion, difficulties in swallowing
• fluid accumulation
• muscle spasms, loss of strength
• dark urine
• weakness
• hot flushes

Rare

• excitement, anxiety, disorientation
• headache
• numbness, tingling or prickling sensation, fits
• blurred vision
• breathlessness, abnormal breathing patterns
• indigestion with fullness in upper abdomen or pain, heartburn
• urinary retention, involuntary passing of urine, persistent erection

Stop taking LCD 250 CR TABLET and contact your doctor immediately if you
experience any of the following side effects:

• signs of allergic reactions (such as skin rash, itching, swelling

of your face, lips, tongue or throat, which may cause difficulty in breathing or swallowing)

• chest pain, uneven heartbeat or palpitations
• signs of bleeding in the stomach which may be shown as blood in faeces or darkened faeces
• signs of low blood counts (such as pale skin, fever, tiredness, sore throat or mild bruising and prolonged bleeding after injury)
• signs of neurole
• mental changes including hallucinations, delusions and depression
• fits (convulsions)

How To Manage Side Effects

Nausea and vomiting:

Try to take LCD 250 CR TABLET with or just after a meal or a snack. Stick to
simple meals. Avoid eating rich or spicy food. Consult your doctor if the
symptom does not improve.

Diarrhoea:

Drink lot of fluids such as water or fruit juices to keep yourself hydrated.
Avoid taking any medicine on your own for managing diarrhoea. Consult your
doctor if the symptom does not improve.

Constipation:

Eat fiber rich foods such as fresh fruits, vegetables, cereals and drink plenty
of water. Try to exercise more regularly. Consult your doctor if the symptom
does not improve on its own.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that
contain alcohol because they can make your mouth dry, use mouthwash that is used
only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco
products. Consult your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

LCD 250 CR TABLET is not recommended for use in pregnant women and in women who
think that they might be pregnant. Consult your doctor before taking it.

!### Breastfeeding

LCD 250 CR TABLET is not recommended for use in breastfeeding women. Consult
your doctor before taking it.

!### Driving and Using Machines

Do not drive or operate any heavy tools or machines, as LCD 250 CR TABLET may
cause sudden sleep attacks or can make you feel sleepy suddenly.

!### Alcohol

Avoid consum
you feel dizzier or drowsier.

!### Kidney

LCD 250 CR TABLET should be taken with caution among patients who have or had
any kidney diseases in the past. Consult your doctor before taking it.

!### Liver

LCD 250 CR TABLET should be taken with caution among patients who have or had
any liver diseases in the past. Consult your doctor before taking it.

!### Allergy

Talk to your doctor if you are allergic to Levodopa or Carbidopa.

!### Heart Disease

LCD 250 CR TABLET should be taken with caution among patients with heart disease
(such as previous history of heart attack, heartbeat problems, circulation or
breathing problems). Consult your doctor before taking it.

Others

LCD 250 CR TABLET is not recommended for use in patients who:

• have ever had any forms of skin cancer
• have any unusual moles in the skin that has not yet been examined by the doctor
• have narrow-angle glaucoma (increased pressure in the eye)
• have a severe mental disorder (Ex. severe p

Before taking LCD 250 CR TABLET, inform your physician if you:

• have a history of fits (epilepsy)
• have had an ulcer in the stomach
• have vomited blood
• have any hormonal problems
• have had depression or any other similar mental problems
• have chronic wide-angle glaucoma (a painless eye condition that can affect your vision)
• feel sleepy or having sudden sleep attacks (Ex. Narcolepsy)
• are due to have a surgery
• are due to have a blood/urine test

Use in pediatrics:

LCD 250 CR TABLET is generally not recommended for use in children and
adolescents (aged below 18 years). However, consult your child’s doctor for
advice.

Use in geriatrics:

LCD 250 CR TABLET is considered safe for use in elderly patients (aged 65 years
or above). However, proper dose adjustment and careful monitoring is required in
such patients.

Interactions

A. Drug-Drug interactions:

Before taking LCD 250 CR TABLET, inform your doctor, if you are taking any of
the following medicines:

• medicines used to manage depression (such as isocarboxazid, phenelzine, selegiline, tranylcypromine)
• medicines used to manage tuberculosis (Ex. rifampicin, isoniazid)
• medicines used to manage high blood pressure (Ex. atenolol, propranolol, captopril, enalapril, olmesartan, telmisartan)
• medicines used to manage epilepsy (Ex. carbamazepine, valproic acid, phenytoin)
• medicines used to manage involuntary movements (such as ataxia, dystonia, myoclonus, tardive dyskinesia) Ex. fluphenazine, haloperidol, chlorpromazine or thioridazine
• medicines used to manage iron deficiency (Ex. ferrous fumarate, iron isomaltoside)
• medicines that can reduce muscle stiffness, strain or spasms (such as trihexyphenidyl, orphenadrine, benzatropine and procyclidine)
• papaverine (a medicine used to manage impotence in men)

B. Drug-Food interaction:

Try to avoid eating a heavy meal that includes a lot of protein (such as beef,
pork, fish and eggs) while taking LCD 250 CR TABLET, as it may interfere with
its absor

Overdosage:

If you or anyone else accidentally take too much of LCD 250 CR TABLET, contact
your doctor immediately or go to a hospital straight away.

Synopsis

Drug	:	Carbidopa, Levodopa
Pharmacological Category	:	Dopamine agonists, Decarboxylase inhibitors
Therapeutic Indication	:	Parkinsonism
Dosage Forms	:	Tablet

More Information

• Keep LCD 250 CR TABLET out of reach of children
• Store at room temperature

FAQs About LCD 250 CR TABLET

What foods need to be avoided while taking LCD 250 CR TABLET?

It is better to avoid eating protein rich foods like beef, chicken, pork, fish
and eggs while taking LCD 250 CR TABLET, as it could interfere with its
absor

Are there any medicines that needs to be avoided while taking LCD 250 CR
TABLET?

Before taking LCD 250 CR TABLET, it is better to inform your doctor about all
the medicines that you are taking, to avoid the risk of unwanted side effects.
It is known that LCD 250 CR TABLET can interact with certain medicines used to
manage depression (such as isocarboxazid, phenelzine, selegiline,
tranylcypromine). These medicines should be stopped for at least two weeks
before taking LCD 250 CR TABLET. Also, consult your doctor for more information
about the medicines that needs to be avoided.

How long does it take for LCD 250 CR TABLET to start working?

LCD 250 CR TABLET will start showing its effect after 24 hours. Although, it can
have an effect after one day, it may take up to 7 days to show its complete
effect and so take this medicine at the same time each day as instructed by your
doctor. Avoid eating a heavy meal rich in protein to enhance the risk of
antiparkinsonian effects.

Can I stop taking LCD 250 CR TABLET when the symptoms subside?

No, do not stop taking LCD 250 CR TABLET unless your doctor tells you, because
sudden withdrawal of LCD 250 CR TABLET can cause excessive muscle tightness,
fever and mental changes in patients. Therefore, continue to take LCD 250 CR
TABLET as informed by your physician.

Can LCD 250 CR TABLET make you feel sleepy?

Yes, LCD 250 CR TABLET can make you feel drowsy suddenly or can cause sudden
sleep attacks (like narcolepsy) while doing your daily activities. You may not
be experiencing any drowsiness or notice any warning signs before falling asleep
suddenly. Avoid driving or operating any tools or heavy machines while taking
LCD 250 CR TABLET. If you experience any unusual episodes of sudden sleepiness
or excessive sleepiness during the daytime, consult your doctor.

Can LCD 250 CR TABLET cause dark urine?

Yes, LCD 250 CR TABLET may alter the color of your urine and make it look
darker. This is usually harmless. However, if you experience any blood in urine
or other unusual symptoms consult your doctor immediately.

Is LCD 250 CR TABLET safe to use in pregnant women?

LCD 250 CR TABLET is not recommended for use in pregnant women and in women who
think that they might be pregnant. Consult your doctor for advice before taking
LCD 250 CR TABLET if you are pregnant or planning to get pregnant.