FLUTOP 40 Tablet 10's

Introduction About FLUTOP 40 TABLET

FLUTOP 40 TABLET contains Fluoxetine which belongs to the group of medicines
called Anti-depressants. It is used to manage major depressive episodes,
obsessive-compulsive disorder (mental disorder) and bulimia nervosa (eating
disorder).

Major depressive disorder is a mental health disorder characterized by a
persistent and intense feeling of sadness for an extended duration of time. It
mainly impacts mood, behavior and other physical functions, such as sleep and
appetite.

Obsessive-compulsive disorder (OCD) is a mental disorder that is associated with
repetitive thoughts (obsessions) and the urge to do things over and again
(compulsions).

Bulimia nervosa is a serious eating disorder that is characterized by binge
eating followed by methods to avoid being overweight such as vomiting, severe
exercise or fasting.

Before taking FLUTOP 40 TABLET, inform your doctor if you have or ever had
epilepsy or fits, history of m
glaucoma.

FLUTOP 40 TABLET is not recommended for use in pregnancy and breastfeeding women
as it may harm the unborn baby. Consult your doctor for advice.

The most common side effects of taking FLUTOP 40 TABLET are insomnia, headache,
diarrhea, feeling sick (nausea) and fatigue. Contact your physician if any of
the above side effects worsen.

Uses Of FLUTOP 40 TABLET

Manage:

• major depressive episodes
• obsessive-compulsive disorder (mental disorder)
• bulimia nervosa (eating disorder)

How FLUTOP 40 TABLET Works

FLUTOP 40 TABLET works by increasing the levels of serotonin, a chemical
messenger in the brain. This improves mood and physical symptoms of depression
and relieves symptoms of p

How to use FLUTOP 40 TABLET

Take FLUTOP 40 TABLET as advised by your physician. Swallow the medicine with a
glass of water. Do not crush or chew the medicine.

Your physician will decide the correct dose and duration for you depending upon
your age, body weight and disease condition. Do not stop taking FLUTOP 40 TABLET
without consulting your doctor.

Side Effects Of FLUTOP 40 TABLET

Common

• insomnia
• headache
• diarrhea
• nausea
• fatigue
• not feeling hungry, weight loss
• nervousness, anxiety
• poor concentration
• sleepiness, unusual dreams, tiredness
• dizziness
• change in taste
• uncontrollable shaking movements
• blurred vision
• rapid and irregular heartbeat sensation
• flushing
• yawning
• indigestion, vomiting
• dry mouth
• rash, urticaria, itching
• excessive sweating
• joint pain
• passing urine more frequently
• unexplained vaginal bleeding
• feeling shaky or chills

Uncommon

• feeling detached from yourself
• strange thinking
• abnormally high mood
• orgasm problems
• teeth grinding
• muscle twitching, problems with balance or coordination
• memory impairment
• enlarged (dilated) pupils
• ringing in the ears
• low blood pressure
• shortness of breath
• nose bleeds
• difficulty swallowing
• hair loss
• increased tendency to bruising or bleeding
• difficulty passing urine
• feeling hot or cold
• abnormal liver function test results
• feeling general discomfort or illness
• memory problems

Rare

• low salt levels in the blood
• reduced platelets in the blood, decrease in white blood cells
• untypical wild behaviour
• hallucinations
• agitation
• p
• confusion
• stuttering
• aggression
• fits
• vasculitis (inflammation of a blood vessel)
• rapid swelling of the tissues around the neck, mouth, face or throat
• pain in the tube that takes food or water to the stomach
• hepatitis (inflammation of the liver)
• lung problems
• sensitivity to sunlight
• muscle pain
• producing breast milk

Stop taking FLUTOP 40 TABLET and contact your doctor immediately if you
experience any of the following side effects:

• self-harming thoughts
• rash or allergic reaction such as itching, swelling of face, neck, lips, tongue, mouth or throat or wheezing/shortness of breath
• restlessness and cannot sit or stand still, may have akathisia
• a combination of symptoms (serotonin syndrome) including unexplained fever with faster breathing or heart rate, sweating, muscle stiffness or tremor, confusion, extreme agitation or sleepiness
• drowsiness, weakness or confusion (mostly in elderly people)
• prolonged and painful erection
• irritability and extreme agitation
• fast or irregular heart rate, collapsing, fainting or dizziness upon standing which may indicate abnormal functioning of the heart rate
• widespread rash, circular, irregular red patches on the hands and arms (Erythema Multiforme), severe skin rash with fever, redness, blisters or ulcers (Stevens-Johnson Syndrome), severe rash involving reddening, peeling and swelling of the skin resembling severe burns (Toxic Epidermal Necrolysis)
• bleeding from stomach or intestines Ex. black tarry stools, unexplained bruise or bleeding and fever, sore throat, tiredness due to decreased blood cells
• yellowing of the skin or eyes (jaundice) or tiredness, pain in abdomen, joints or muscles

How To Manage Side Effects

Nausea or Vomiting:

Take this medicine with or just after meals. Stick to simple meals. Avoid eating
oil-rich or spicy foods. Contact your doctor if nausea and vomiting do not
improve.

Diarrhea:

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not
take any medicine on your own for managing diarrhea. Contact your doctor if your
if it persists for a long time.

Headache:

Rest and relax. Drink plenty of fluids such as water and electrolytes. Apply a
pain-relieving balm on the head if necessary. Do not consume alcohol. Contact
your doctor if your headache did not improve.

Dizziness or Drowsiness:

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines
while you are feeling dizzy. Do not drink alcohol, as it can aggravate your
dizziness. Contact your doctor if your dizziness or drowsiness did not improve.

Warning & Precautions

!### Pregnancy

FLUTOP 40 TABLET is not recommended for use especially in the last 3 months of
pregnancy as it harms the unborn baby. It should be used with caution during
late pregnancy or just before giving birth. Consult your doctor before taking
FLUTOP 40 TABLET.

!### Breastfeeding

FLUTOP 40 TABLET will be excreted through breast milk., hence it should be used
with caution if it is clearly necessary. Your doctor will lower the dose
accordingly. Consult your doctor before taking FLUTOP 40 TABLET.

!### Driving and Using Machines

Do not drive or operate any machines as it may affect your judgement or
coordination after taking FLUTOP 40 TABLET.

!### Alcohol

Avoid consum
before taking.

!### Kidney

FLUTOP 40 TABLET should be used with caution in patients with kidney problems.
Consult your doctor before taking FLUTOP 40 TABLET.

!### Liver

FLUTOP 40 TABLET should be used with caution in patients with liver problems.
Consult your doctor before taking FLUTOP 40 TABLET.

!### Allergy

Do not take FLUTOP 40 TABLET if you are allergic to Fluoxetine or to any other
ingredients of this medicine.

!### Lungs

FLUTOP 40 TABLET should be used with caution in patients with lung problems.
Consult your doctor before taking FLUTOP 40 TABLET.

!### Heart Disease

FLUTOP 40 TABLET should be used with caution in patients with heart problems or
low heart rate. Consult your doctor before taking FLUTOP 40 TABLET.

Others

Before taking FLUTOP 40 TABLET, inform your doctor if you:

• have or ever had epilepsy or fits
• have history of m
• have diabetes
• have glaucoma
• have ongoing ECT (electroconvulsive therapy)
• have a history of bleeding disorder

Use in pediatrics:

Your doctor will give the right dose depends on your child’s age, body weight
and disease condition. Consult your doctor for advice before taking.

Use in geriatrics:

FLUTOP 40 TABLET should be used with caution in elderly patients (above 70 years
of age). Consult your doctor before taking FLUTOP 40 TABLET.

Interactions

A. Drug-Drug interactions:

Before taking FLUTOP 40 TABLET, inform your doctor if you are taking any of the
following medicine:

• medicine used to manage depression (Ex. tranylcypromine, moclobemide iproniazid, nialamide, isocarboxazid, toloxatone)
• linezolid (used for bacterial infections)
• methylthioninium chloride (used to manage methaemoglobinaemia)
• selegiline (used for parkinson's disease)
• lithium (used to m
• L- tryptophan (used to manage premenstrual disorders)
• medicines used to manage epilepsy (Ex. phenytoin, carbamazepine, oxcarbazepine)
• medicine used as a pain killer (Ex. tramadol)
• medicine used to manage migraine (Ex. sumatriptan)
• medicine used to manage heart’s rhythm (Ex. Class IA and III antiarrhythmics like quinidine and amiodarone)
• medicine used as antipsychotics (Ex. phenothiazine derivatives like fluphenazine, pimozide, haloperidol)
• medicine used as antimicrobial agents (Ex. sparfloxacin, moxifloxacin, erythromycin IV, pentamidine)
• medicine used to manage malaria (Ex. halofantrine, mefloquine, chloroquine)
• medicines used to manage allergies (astemizole, mizolastine, mequitazine, cyproheptadine)
• medicine used for heart problems (Ex. flecainide or encainide)
• nebivolol (medicines used for high blood pressure)
• atomoxetine (medicines used to manage attention deficit hyperactivity disorder)
• chlorothiazide (used to remove sodium and water from the body)
• desmopressin (used to reduce the amount of urine produced by the kidneys)
• medicine used for depression (Ex. imipramine, desipramine, amitriptyline and selective serotonin reuptake inhibitors Ex. citalopram, escitalopram) and or St John’s wort (herbal medicine)
• medicine used to manage breast cancer (Ex. tamoxifen)
• medicine used to thin the blood (Ex. warfarin, aspirin)
• ibuprofen, diclofenac, tramadol (medicines used to manage pain)
• medicines used to manage certain mental disorders (Ex. clozapine)
• metoprolol (medicines used for heart failure)
• buprenorphine/naloxone (medicines used for opioid dependence)
• bupropion (medicines helps to stop smoking)

Overdosage:

If you or anyone else accidentally took too much of FLUTOP 40 TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdosage are
nausea, vomiting, seizures, heart problems (ranging from irregular heartbeat
with no symptoms, heart attack (cardiac arrest), lungs not working properly
(pulmonary dysfunction), central nervous system (CNS) alterations (excitation
and an altered level of consciousness or loss of consciousness) or coma.

Synopsis

Drug	:	Fluoxetine
Pharmacological Category	:	Anti-depressants
Therapeutic Indication	:	Major depressive episodes, Obsessive-compulsive disorder, Bulimia nervosa
Dosage Forms	:	Tablet, Capsule, Suspension

More Information

• Keep FLUTOP 40 TABLET out of reach of children
• Store at a temperature below 25°C

FAQs About FLUTOP 40 TABLET

For what conditions FLUTOP 40 TABLET is used?

FLUTOP 40 TABLET is used to manage major depressive episodes,
obsessive-compulsive disorder (mental disorder) and bulimia nervosa (eating
disorder). Contact your before taking FLUTOP 40 TABLET.

Is it safe to use FLUTOP 40 TABLET if I have glaucoma?

Yes. FLUTOP 40 TABLET may cause increased pressure in the eye in patients having
glaucoma. Consult your doctor before taking FLUTOP 40 TABLET.

Is it safe to use FLUTOP 40 TABLET in elder people?

Yes. FLUTOP 40 TABLET should be used with caution in elderly patients (above 70
years of age). Consult your doctor before taking FLUTOP 40 TABLET.

Can I take FLUTOP 40 TABLET if I have diabetes?

Yes. FLUTOP 40 TABLET should be taken with caution in patients with diabetes as
it might fluctuate blood glucose levels. Monitor blood sugar levels frequently.
Consult your doctor before taking FLUTOP 40 TABLET.

What are the common side effects of FLUTOP 40 TABLET?

The most common side effects of taking FLUTOP 40 TABLET are insomnia, headache,
diarrhea, feeling sick (nausea) and fatigue. Contact your physician if any of
the above side effects worsen.