DIANORM TOTAL 60 Tablet 15's

Introduction About DIANORM TOTAL 60MG TABLET

DIANORM TOTAL 60MG TABLET is a combination of Gliclazide, Metformin and
Pioglitazone which belongs to the group of medicines called Antidiabetic agents.
It is used in adults to manage type II diabetes mellitus when diet, exercise and
management with single agents does not result in adequate sugar control.

Type II diabetes mellitus is a chronic disease characterized by abnormally high
levels of glucose in the blood. It is caused due to inadequate production of a
hormone called insulin (produced by pancreas to metabolize glucose) in the body
or due to inadequate sensitivity of body cells to the actions of insulin.

Before taking DIANORM TOTAL 60MG TABLET, inform your doctor if you have any
liver, kidney or heart problems. You must also inform your doctor if you have
any eye problems, hormonal imbalance, alcoholism, or if you are malnourished,
starved, on an irregular diet as a precaution.

DIANORM TOTAL 60MG TABLET is strictly not recommended for use in patients with
type I diabetes mellitus, bladder cancer, severe heart failure or lactic
acidosis. It is also not suitable for use in pregnant or breastfeeding women.

Along with the management, follow the diet and lifestyle changes advised by your
doctor to achieve better results. Avoid smoking and consum
taking DIANORM TOTAL 60MG TABLET as it may aggravate your existing condition.

The most common side effects of taking DIANORM TOTAL 60MG TABLET are low blood
sugar levels, nausea, stomach upset, constipation, sore throat, muscle pain,
headache, dizziness and weight gain. Consult your doctor if any of these side
effect worsens.

Uses Of DIANORM TOTAL 60MG TABLET

• Management of Type II diabetes mellitus

How DIANORM TOTAL 60MG TABLET Works

DIANORM TOTAL 60MG TABLET stimulates the pancreas to secrete more insulin (a
hormone involved in glucose metabolism). It also makes our body more sensitive
to insulin which helps in digesting the circulating sugars (glucose) in the
blood, thereby reducing blood sugar levels. Additionally, it can also reduce the
glucose produced by the liver and reduces its absoprtion in the body.

How to use DIANORM TOTAL 60MG TABLET

Take DIANORM TOTAL 60MG TABLET preferably just before meals or during meals or
as advised by your physician. Swallow the medicine with a glass of water. Do not
crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition.

Do not stop taking DIANORM TOTAL 60MG TABLET unless your doctor advice you to
stop.

Side Effects Of DIANORM TOTAL 60MG TABLET

Common

• hypoglycemia (low blood sugar levels)
• nausea, vomiting
• diarrhea, stomach pain, loss of appetite, flatulence
• changes in taste, metallic taste
• headache, dizziness
• joint pain, back pain, muscle pain
• impotence
• respiratory infection, sinus infection, sore throat
• weight gain

Uncommon

• difficulty in sleeping (insomnia)
• proteins in urine
• spinning sensation (vertigo)

Stop taking DIANORM TOTAL 60MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)
• symptoms of heart failure (such as unusual shortness of breath or trouble in breathing, rapid increase in weight or localised swelling (oedema), especially in the ankles or legs, unusual tiredness)
• signs and symptoms of bladder cancer (such as blood in your urine, pain while urinating or urgent need to pee)
• increased risk of fractures (especially in the bones of hand, upper arm, or foot in women)
• blurred vision due to swelling at the back of the eye or worsening of existing blurred vision
• serious allergic reaction (such as hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
• signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)

How To Manage Side Effects

!### Bloating

To manage flatulence, consider dietary adjustments and lifestyle changes.
Identify and limit gas-producing foods such as beans, cabbage, and carbonated
drinks. Chew food thoroughly to aid digestion and reduce the likelihood of
swallowing air. Introduce probiotics through yogurt or supplements to promote a
healthy gut flora. Regular physical activity can also aid digestion. If
persistent, consult a healthcare professional to rule out underlying issues and
discuss potential solutions, such as medications or further dietary
modifications.

!### Dizziness Or Drowsiness

Managing dizziness involves addressing potential underlying causes and making
lifestyle adjustments. If you experience sudden or severe dizziness, it's
important to sit or lie down to manage the risk of falling. Ensure proper
hydration and maintain a balanced diet to regulate blood sugar levels. Avoid
sudden movements and try to rise slowly from a seated or lying position. If
dizziness persists, it's advisable to consult with a healthcare professional to
rule out any serious medical conditions.

Headache

Stay well-hydrated, as dehydration can contribute to headaches. Get adequate
rest and maintain a regular sleep schedule. Practice stress-management
techniques, such as deep breathing or meditation, to alleviate tension.
Over-the-counter pain relievers like acetaminophen or ibuprofen can provide
relief, but it's essential to follow recommended dosages. Applying a cold or
warm compress to the forehead may also ease discomfort. If headaches persist or
worsen, seek medical advice to rule out underlying issues and receive
appropriate> management.

!### Hypoglycemia

Managing hypoglycemia, or low blood sugar, involves prompt action to raise blood
glucose levels and manage complications. When experiencing hypoglycemia,
individuals should quickly consume a source of rapidly-absorbed carbohydrates,
such as glucose tablets, fruit juice, or regular soda. Waiting for about 15
minutes and rechecking blood sugar levels is crucial to ensure they rise to a
safe range. If hypoglycemia persists, additional carbohydrate intake may be
necessary. Once blood sugar levels stabilize, a small snack containing both
carbohydrates and protein can help sustain them. Regular monitoring and
consultation with a healthcare professional are essential for developing a
personalized plan to manage hypoglycemia effectively. In severe cases, emergency
assistance may be required.

!### Nausea And Vomiting

To manage nausea and vomiting, it is essential to focus on hydration, rest, and
dietary adjustments. Stay well-hydrated by sipping on clear fluids like water or
ginger tea. Opt for small, frequent meals to ease the digestive process,
avoiding strong-smelling or heavy foods. Ginger, known for its anti-nausea
properties, can be consumed through tea or candies. Adequate rest is crucial for
recovery, allowing your body to heal. If symptoms persist, consult a healthcare
professional who may recommend medications or other interventions tailored to
the underlying cause of nausea and vomiting.

Warning & Precautions

!### Pregnancy

ContraindicatedDIANORM TOTAL 60MG TABLET is not recommended for use in pregnant women.
Therefore, consult your doctor before taking it.

!### Breastfeeding

ContraindicatedDIANORM TOTAL 60MG TABLET is not recommended for use in breastfeeding women.
Therefore, consult your doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected
by DIANORM TOTAL 60MG TABLET.

!### Alcohol

Consult your doctorAvoid consum
increase the risk of unwanted side effects.

!### Kidney

Consult your doctorDIANORM TOTAL 60MG TABLET is not recommended for use in patients with severe
kidney problems. It should be used with caution in patients with other kidney
problems. Therefore, consult your doctor before taking it.

!### Liver

Consult your doctorDIANORM TOTAL 60MG TABLET is not recommended for use in patients with severe
liver problems. It should be used with caution in patients with other liver
problems. Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take DIANORM TOTAL 60MG TABLET if you are allergic to Gliclazide,
Metformin, Pioglitazone or to any other sulfonylureas (Ex. glyburide,
glimepiride) or sulphonamides (Ex. sulfasalazine).

!### Lungs

ContraindicatedDIANORM TOTAL 60MG TABLET is not recommended for use in patients with breathing
problems (such as asthma or COPD). Therefore, consult your doctor before taking
it.

!### Heart Disease

Consult your doctorDIANORM TOTAL 60MG TABLET is not recommended for use in patients with severe
heart problems (such as heart failure). It should be used with caution in
patients with other heart problems. Therefore, consult your doctor before taking
it.

!### Use In Pediatrics

ContraindicatedDIANORM TOTAL 60MG TABLET is not recommended for use in children and in
adolescents (aged below 18 years). Therefore, consult your doctor before taking
it.

!### Use In Geriatrics

Use with CautionDIANORM TOTAL 60MG TABLET should be used with caution in elderly patients (aged
above 65 years). Therefore, consult your doctor before taking it.

Others

DIANORM TOTAL 60MG TABLET is not recommended for use if you:

• have type I diabetes mellitus (insulin dependent diabetes)
• have lactic acidosis (build-up of lactic acid in the body)
• have diabetic ketoacidosis (a diabetic complication causing episodes of fatigue, nausea, frequent urination and muscular stiffness)
• have bladder cancer
• pass bloody urine
• are scheduled for any surgery
• recently met with any accident
• have any serious infection

Before taking DIANORM TOTAL 60MG TABLET, inform your doctor if you:

• are recovering from any injury, operation, infections or from any form of stress
• have G6PD deficiency
• are on fating or malnourished, starved, on an irregular diet, or feeling weak
• perform extreme physical exercises without proper carbohydrate intake
• are severely dehydrated
• have hormonal problems (Ex. disorders of pituitary gland, adrenal cortex or thyroid gland)
• are an alcoholic
• have edema (swelling of body parts)
• smoke
• have special type of diabetic eye disease called macular oedema (swelling of the back of the eye with worsening of your vision)
• have cysts on your ovaries (polycystic ovarian syndrome)
• previously had stroke
• have anemia (low RBC in blood)
• have any bone problems or at risk of developing bone fractures
• are a premenopausal woman
• have thyroid problems

Interactions

A. Drug-Drug Interactions:

Before taking DIANORM TOTAL 60MG TABLET, inform your doctor if you are taking
any of the following medicines:

• other antidiabetic agents (such as teneligli
• pain killers (Ex. aspirin, ibuprofen, celecoxib, phenylbutazone, azopropazone, oxyphenbutazone)
• antibiotics for UTI (amikacin, nitrofurantoin, sulfamethoxazole)
• other antibiotics (such as tetracyclines, chloramphenicol, ciprofloxacin, clarithromycin)
• antifungal agents (Ex. fluconazole, miconazole, isuvaconazole)
• medicines used for male sex hormone replacement therapy (Ex. testosterone)
• antidepressants (such as moclobemide, isocarboxazid, phenelzine, tranylcypromine, fluoxetine, St.John’s Wort)
• H2 receptor antagonist (such as r
• lipid lowering agents (Ex. fenofibrate, nicotinic acid, colesevelam)
• antihypertensive agents (Ex. enalapril, lisinopril, ramipril, atenolol, propranolol, telmisartan, olmesartan, clonidine, guanethidine and reserpine)
• anticancer agents (Ex. cyclophosphamide, ifosfamide, trofosfamide, vandet
• anti-allergic medicines (Ex. tritoqualine)
• hormonal replacement therapy (used to manage menstrual disorders in women) Ex. estradiol
• thiazide diuretics (used to manage edema and high blood pressure) Ex. hydrochlorothiazide
• antipsychotic drugs (such as chlorpromazine, prochlorperazine, lithium)
• corticosteroids (used to manage pain and inflammation) Ex. prednisolone, betamethasone
• anti-asthmatics (Ex. salbutamol, terbutaline)
• anti-epile
• cimetidine (a medicine used to manage stomach ulcers)
• rifampicin (an anti-TB medicine)
• dolutegravir (an antiviral agent)
• ranolazine (a medicine used in the management of chest pain)
• trimethoprim (an antibiotic)
• ritodrine (a medicine used in the management of premature labour)

Overdosage:

If you or anyone else accidentally took more DIANORM TOTAL 60MG TABLET, you may
experience the signs of hypoglycemia (such as increased hunger, sweating,
headache, feeling clammy, restless or aggressive, shakiness, fast heartbeat and
confusion). To manage this, consume any sugary food immediately. If the symptom
did not improve or worsens contact your doctor immediately. Other symptoms of
overdosage might include vomiting, stomach pain with muscle cramps, feeling
generally unwell with severe tiredness and difficulty in breathing.

Synopsis

Drug	:	Gliclazide, Metformin, Pioglitazone
Pharmacological Category	:	Sulfonylureas, Bigu
Therapeutic Indication	:	Type II diabetes mellitus
Dosage Forms	:	Tablet

More Information

• Keep DIANORM TOTAL 60MG TABLET out of reach of children
• Store DIANORM TOTAL 60MG TABLET at room temperature

FAQs About DIANORM TOTAL 60MG TABLET

Q: What is DIANORM TOTAL 60MG TABLET used for?

A: DIANORM TOTAL 60MG TABLET is an antidiabetic medicine used in the management
of Type II diabetes mellitus when diet, exercise and management with single
agents does not result in adequate response.

Q: How and when to take DIANORM TOTAL 60MG TABLET?

A: Take DIANORM TOTAL 60MG TABLET preferably just before meals or during meals
or as advised by your physician. Swallow the medicine with a glass of water. Do
not cursh or chew the medicine. Your doctor will decide the correct dose and
duration of therapy for you depending upon your age, body weight and disease
condition.

Q: How long should I take DIANORM TOTAL 60MG TABLET?

A: You need to take DIANORM TOTAL 60MG TABLET as long as your doctor or
physician prescribes you the medicine. Your doctor will decide the correct dose
and duration of therapy for you depending upon your age, body weight and disease
condition.

Q: What is the best time to take DIANORM TOTAL 60MG TABLET?

A: DIANORM TOTAL 60MG TABLET must be just before meals or during meals to avoid
gastrointestinal side effects.

Q: What to do if I forgot to take a dose of DIANORM TOTAL 60MG TABLET?

A: If you forgot to take a dose of DIANORM TOTAL 60MG TABLET, take it as soon as
you remember. However, if it is time for the next dose of DIANORM TOTAL 60MG
TABLET, skip the missed dose and take the next one regularly. Do not take a
double dose of DIANORM TOTAL 60MG TABLET to compensate the missed ones.

Q: Can I stop taking DIANORM TOTAL 60MG TABLET without consulting your doctor?

A: No. You should not stop taking DIANORM TOTAL 60MG TABLET without consulting
your doctor because it may lead to reversal of symptoms. If you feel better
after using DIANORM TOTAL 60MG TABLET, consult your doctor for advice.

Q: Will taking a higher dose of DIANORM TOTAL 60MG TABLET be more effective?

A: No, taking a higher dose of DIANORM TOTAL 60MG TABLET will not be effective
rather it can lead to toxicity. Always take the dose prescribed by your doctor.
If the prescribed dose is not effective for you, consult your doctor for advice.
Your doctor might increase the dose or suggest an alternative therapy.

Q: Can I take medication for high blood pressure along with DIANORM TOTAL 60MG TABLET?

A: It is not advisable to take medicines to control blood pressure while taking
DIANORM TOTAL 60MG TABLET without consulting your doctor, as they have known
interactions with DIANORM TOTAL 60MG TABLET.

Q: How to manage the side effects of DIANORM TOTAL 60MG TABLET?

A: Low blood sugar is a common side effect of taking DIANORM TOTAL 60MG TABLET.
Try to have sugar rich food items such as fruit juice, glucose tablets or gel,
soft drinks, honey or sugary candy. Check your blood sugar after 10 minutes. If
not gained o
blood sugar levels once again. If your condition did not improve, consult your
doctor immediately.

Q: Can DIANORM TOTAL 60MG TABLET be taken with insulin?

A: Co-administration of DIANORM TOTAL 60MG TABLET with insulin is considered
risky as they can increase the chances of hypoglycemia (low blood sugar levels).
Therefore, consult your doctor before taking it.

Q: Can DIANORM TOTAL 60MG TABLET be used in pregnant women?

A: DIANORM TOTAL 60MG TABLET is not recommended for use in pregnant women.
Therefore, consult your doctor for advice before taking it.

Q: Does DIANORM TOTAL 60MG TABLET cause bone fractures?

A: DIANORM TOTAL 60MG TABLET may cause bone fractures in some individuals.
Therefore, it is important for you to inform your doctor before taking DIANORM
TOTAL 60MG TABLET if you have any bone problems or at risk of developing any
bone fractures (such as menopause).

Q: Does DIANORM TOTAL 60MG TABLET cause weight gain?

A: Yes. DIANORM TOTAL 60MG TABLET may cause weight gain in some individuals. To
avoid this, follow a healthy diet and regular physical activity as advised by
your physician. However, if you experience any weight gain due to swelling of
body parts (such as in face, legs, or hands), consult your doctor immediately.

Q: What are the side effects of taking DIANORM TOTAL 60MG TABLET?

A: The most common side effects of taking DIANORM TOTAL 60MG TABLET are low
blood sugar levels, nausea, stomach upset, constipation, sore throat, muscle
pain, headache, dizziness and weight gain. Consult your doctor if any of these
side effect worsens.

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Post Prandial Blood Sugar (PPBS)
• medicalslot Diabetic Checkup
• Advance Diabetes Monitoring (Senior Female)