Cytax 100mg Injection 16.7ml

Introduction About CYTAX 100MG INJECTION

CYTAX 100MG INJECTION contains Paclitaxel which belongs to a group of
anti-cancer medicines called Taxanes. CYTAX 100MG INJECTION is used to manage
ovarian and breast cancer as a first line of therapy and as a second line of
management when platinum containing medicines (such as cisplatin) or
anthracyclines are insufficient to manage the disease in affected individuals.

CYTAX 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung
cancer) when surgery/radiation therapy is not suitable. The medicine is also
indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements
(such as anthracyclines) are insufficient to manage the disease in affected
individuals.

CYTAX 100MG INJECTION is not recommended for use in patients allergic to
paclitaxel and polyoxyethylated castor oil. It is also not recommended for use
in patients with few white blood cells count and serious & uncontrolled
infection. The medicine is also not used in patients suffering from severe liver
disease.

Before receiving CYTAX 100MG INJECTION, inform your doctor if you had previously
received radiation to your chest and/or suffering from thrombocytopenia (low
platelet count)/acute infections (such as herpes zoster, chickenpox, herpes),
kidney problems (such as chronic kidney disease), liver problems (such as
mild/moderate hepatic impairment) and/or heart problems (such as severe coronary
artery disease, myocardial infarction and arrhythmias).

CYTAX 100MG INJECTION is not recommended for use during pregnancy. Women of
child-bearing potential should use effective contrace
receiving CYTAX 100MG INJECTION which should be continued for next-6 months
after completing the management. The medicine is also not recommended for use in
breastfeeding women.

CYTAX 100MG INJECTION is also not recommended for use in children and
adolescents (aged below 18 years). The medicine can be used with caution in
elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of receiving CYTAX 100MG INJECTION are minor
allergic reactions (such as flushing, rash, itching), shortness of breath, sore
throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult
your doctor if any of these symptoms worsen.

Uses Of CYTAX 100MG INJECTION

• Manage ovarian and breast cancer.
• Manage advanced NSCLC (non-small cell lung cancer)
• Manage AIDS-related Kaposi’s sarcoma in affected individuals.

How CYTAX 100MG INJECTION Works

CYTAX 100MG INJECTION works by interfering with the microtubule structures in
the cell (substance which aids cancer cells to divide and multiply) thus
inhibiting the growth of cancer cells and managing its spread in affected
individuals.

How to use CYTAX 100MG INJECTION

CYTAX 100MG INJECTION will be given to you only by a doctor or a nurse into a
vein as an intravenous infusion. Your doctor will decide the correct dose and
duration for you depending upon your age, body weight and disease condition.

Side Effects Of CYTAX 100MG INJECTION

Common

• minor allergic reactions such as flushing, rash and/or itching
• infections such as upper respiratory infection, urinary tract infection
• shortness of breath
• sore throat/mouth ulcers, sore and red mouth
• diarrhea, nausea, vomiting
• loss of hair
• pain in the muscles, cramps, joints
• fever, severe chills, headache, dizziness, tiredness, looking pale
• bleeding, bruising more easily than normal
• signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs
• temporary mild nail change and skin changes
• reactions at injection sites such as localized swelling, pain and/or redness of the skin.

Uncommon

• se
• racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block
• fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat
• back pain, chest pain, pain around hands and feet, chills, abdominal pain.

Rare

• febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection
• motor neuropathy (disease that affects your body’s motor nerves)
• pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest)
• bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis)
• skin redness
• peritonitis (inflammation of abdominal layer)
• fever, dehydration, weakness
• anaphylactic reactions (life threatening allergic reaction).

How To Manage Side Effects

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on
your own to manage diarrhea. Consult your doctor and inform them if the symptom
gets worse.

Nausea and vomiting:

Try to receive CYTAX 100MG INJECTION with or just after a meal or a snack. Stick
to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom
gets worse.

Headache:

If CYTAX 100MG INJECTION causes headache, then take rest and drink plenty of
fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a
painkiller. Headaches should usually go away after the first week of receiving
CYTAX 100MG INJECTION. If it lasts more than a week or severe, inform your
doctor.

Dizziness:

Try to rest and get enough sleep. Try to avoid driving or operating any tools or
machines while you feel dizzy. Limit consum
dizziness. Consult and inform your doctor if the symptom worsens.

Tiredness:

Make sure you take rest and drink plenty of fluids. Avoid or limit the
consum
can sit down (or lie down) when the symptoms are at their worst. Avoid driving
or using tools or machinery until you feel well.

Warning & Precautions

!### Pregnancy

CYTAX 100MG INJECTION is generally not recommended for use in pregnant women.
Women with child-bearing potential should use effective contrace
while receiving CYTAX 100MG INJECTION which should be continued for next-6
months after completing the> management. Consult your doctor before receiving
CYTAX 100MG INJECTION.

!### Breastfeeding

CYTAX 100MG INJECTION is not recommended for use in breastfeeding women as it is
not known whether the medicine pass through breast milk. Consult your doctor
before receiving the medicine.

!### Driving and Using Machines

Do not drive or use heavy machines if you feel dizzy/tired after receiving CYTAX
100MG INJECTION.

!### Alcohol

Avoid consum
cause harmful effects to the patient.

!### Kidney

CYTAX 100MG INJECTION should be used with caution in patient with chronic kidney
disease. Consult your doctor before receiving CYTAX 100MG INJECTION.

!### Liver

CYTAX 100MG INJECTION is not recommended for use in patients with severe hepatic
impairment. It should be used with caution in patients with mild to moderate
hepatic impairment. Consult your doctor before receiving the medicine.

!### Allergy

Do not receive CYTAX 100MG INJECTION if you are allergic to paclitaxel,
polyoxyethylated castor oil and/or any other ingredients of this medicine.

!### Heart Disease

CYTAX 100MG INJECTION should be used with caution in patients with heart
conduction problems, severe coronary artery disease, myocardial infarction and
arrhythmias. Consult your doctor before receiving the medicine.

Others

CYTAX 100MG INJECTION is not recommended for use if you:

• have too few white blood cells count
• have serious and uncontrolled infection.

Before receiving CYTAX 100MG INJECTION, inform your doctor if you:

• have signs of bone marrow suppression such as fever, sever chills, sore throat and/or mouth ulcers
• had previous radiation to your chest
• have signs of mucositis such as sore/red mouth
• suffer from thrombocytopenia (low platelet count)
• suffer from acute infections (such as herpes zoster, chickenpox, herpes).

Use in Pediatrics:

CYTAX 100MG INJECTION is not recommended for use in children and adolescents
(aged below 18 years). Consult your doctor before receiving the medicine.

Use in Geriatrics:

CYTAX 100MG INJECTION should be used with caution in elderly patients (aged
above 65 years). Consult your doctor before receiving the medicine.

Interactions

A. Drug - Drug interactions:

Before receiving CYTAX 100MG INJECTION, inform your doctor if you are taking any
of the following medicine:

• erythromycin, rifampicin (medicines used to manage infections)
• ketoconazole (used for fungal infections)
• fluoxetine (used to stabilize mood)
• carbamazepine, phenytoin (used to manage seizures/epilepsy)
• gemfibrozil (used to lower blood lipid levels)
• cimetidine (used for heartburn/stomach ulcers)
• ritonavir, saquinavir, indinavir, nelfinavir, efavirenz, nevirapine (used to manage HIV and AIDS)
• clopidogrel (used to manage blood clots)
• verapamil, quinidine (used to manage irregular heart rhythms)
• diazepam (used to manage anxiety, muscle spasm, seizures)
• cyclosporine (used to manage rejection of transplanted organ)
• cisplatin (used for testicular cancer)
• cimetidine (used to manage gastroesophageal reflux disease)
• r
• dexamethasone (used for inflammation, severe allergies)
• diphenhydramine (used to manage short term sleep problems).

Overdosage:

CYTAX 100MG INJECTION will be administered to you only by a doctor or a nurse in
a hospital and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Paclitaxel
Pharmacological Category	:	Antineoplastic agents
Therapeutic Indication	:	Ovarian cancer, Breast cancer, Kaposi sarcoma, Non-small cell lung cancer (NSCLC)
Dosage Forms	:	Injection

More Information

• Keep CYTAX 100MG INJECTION out of reach of children
• Do not store CYTAX 100MG INJECTION above 25°C

FAQs About CYTAX 100MG INJECTION

What is CYTAX 100MG INJECTION used for?

CYTAX 100MG INJECTION is used to manage ovarian and breast cancer as a first
line of therapy and as a second line of management when platinum containing
medicines (such as cisplatin) or anthracyclines are insufficient to manage the
disease. It is also used to manage advanced NSCLC (non-small cell lung cancer)
and AIDS-related Kaposi’s sarcoma in affected individuals.

How CYTAX 100MG INJECTION works?

CYTAX 100MG INJECTION works by interfering with the microtubule structures in
the cell (substance which aids cancer cells to divide and multiply) thus
inhibiting the growth of cancer cells and managing its spread in affected
individuals.

What are the most common side effects of receiving CYTAX 100MG INJECTION?

The most common side effects of receiving CYTAX 100MG INJECTION are minor
allergic reactions (such as flushing, rash, itching), shortness of breath, sore
throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult
your doctor if any of these symptoms worsen.

How to administer CYTAX 100MG INJECTION?

CYTAX 100MG INJECTION will be given to you only by a doctor or a nurse into a
vein as an intravenous infusion. Your doctor will decide the correct dose and
duration for you depending upon your age, body weight and disease condition.

Can CYTAX 100MG INJECTION be used in pregnant women?

No, CYTAX 100MG INJECTION is not recommended for use in pregnant women. Women
with child-bearing potential should use effective contrace
receiving CYTAX 100MG INJECTION which should be continued for next-6 months
after completing the management. Consult your doctor before receiving CYTAX
100MG INJECTION.

Useful Diagnostic Tests

• Mammogram
• CA-125 blood test