ZOLIDPOS Tablet 10's

Introduction About ZOLIDPOS TABLET

ZOLIDPOS TABLET contains Linezolid, which belongs to the group of medicines
called Antibiotics. It is used to manage bacterial infections like pneumonia
(nosocomial and community-acquired pneumonia), some infections in or under the
skin (complicated skin and soft tissue infections), and blood infections.

Bacterial infections are caused by the multiplication of specific harmful
strains of bacteria anywhere in the body. It is generally characterized by
fever, chills and sweat, swollen lymph nodes, sudden pain or its worsening,
unexplained tiredness, headache, skin flushing or discomfort, nausea, vomiting,
diarrhea, or stomach pain.

Before taking ZOLIDPOS TABLET, inform your doctor if you have liver, kidney, or
heart problems, mental health problems (such as m
schizoaffective disorder), overactive thyroid, anemia, history of seizures,
diarrhea, adrenal gland tumors (phaeochromocytoma), or carcinoid syndrome, and
if you are prone to getting infections.

During management with ZOLIDPOS TABLET, your doctor might perform regular blood
tests to monitor your blood count and your eyesight if you take ZOLIDPOS TABLET
for more than 28 days.

ZOLIDPOS TABLET is not recommended for use in pregnant women unless advised by
the doctor, and it is not recommended for use in breastfeeding women. ZOLIDPOS
TABLET is not recommended for use in children and adolescents (below 18 years of
age), and it should be used with caution in elderly patients (aged 65 years and
above).

The most common side effects of taking ZOLIDPOS TABLET are headache, dizziness,
nausea, vomiting, diarrhea, constipation, stomach pain, and indigestion. Consult
your doctor if any of the side effects worsen.

Uses Of ZOLIDPOS TABLET

Manages bacterial infections like:

• pneumonia (nosocomial and community-acquired)
• complicated skin and soft tissue infections
• blood infections

How ZOLIDPOS TABLET Works

ZOLIDPOS TABLET works by binding to and inhibiting bacterial enzymes required in
DNA synthesis, thus interru
multiplication.

How to use ZOLIDPOS TABLET

Take ZOLIDPOS TABLET as advised by your physician.

For Tablet: Swallow ZOLIDPOS TABLET with a glass of water. Do not crush or
chew the medicine.

For Dispersible Tablet: Disperse ZOLIDPOS TABLET in the specified quantity
of water as mentioned on the label. Consume the mixture immediately after
reconstitution.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition. Continue to take
ZOLIDPOS TABLET for the stipulated duration prescribed by your doctor to achieve
better results.

Side Effects Of ZOLIDPOS TABLET

Common

• vaginal or oral thrush (fungal infection)
• headache, dizziness
• metallic taste in the mouth
• diarrhea, nausea, vomiting, localized or general stomach pain, constipation, indigestion
• difficulty in sleeping
• localized pain
• increased blood pressure

Uncommon

• tingling sensation or feeling numb
• swollen, sore, or discoloured tongue
• dry mouth
• frequent urination
• chills
• feeling thirsty
• increased sweating
• kidney failure
• abdominal bloating
• increased or decreased heart rate
• weakness, sensory changes
• inflammation of the vagina or genital area (women)

Rare

• superficial tooth discolouration

Stop taking ZOLIDPOS TABLET and contact your doctor immediately if you
experience any of the following side effects:

• severe skin disorder and allergic reactions (signs include swelling, particularly around the face and neck, wheezing, difficulty breathing, raised purple rash due to inflammation of blood vessels, red sore skin and flaking, rash, and itching)
• vision problems (like blurred vision, changes in color vision, difficulty in seeing detail, or restricted field of vision)
• severe diarrhea with blood or mucus (it may develop into complications that are life-threatening)
• repeated nausea or vomiting, abdominal pain, or rapid breathing
• fits or seizures or serotonin syndrome (signs include agitation, confusion, mental disturbance, rigidity, shaking, incoordination, seizure, rapid heart rate, and severe breathing problems)
• unexplained bleeding or bruising
• changes in the numbers of certain blood cells that may lead to infection (signs of infection include fever, sore throat, mouth ulcers, and tiredness)
• inflammation of the pancreas
• convulsions
• transient ischemic attacks (temporary disturbance of the flow of blood to the brain causing short-term symptoms such as loss of vision, leg and arm weakness, slurring of speech, and loss of consciousness)
• ringing in the ears (tinnitus)

How To Manage Side Effects

!### Constipation

Try to eat more high-fiber foods such as fresh fruit, vegetables, and cereals,
and drink plenty of water. If this does not help, consult your doctor about
receiving alternate management for constipation.

!### Diarrhea

Drink lots of fluids, such as water, to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Try to avoid taking any medicine on your own to manage
diarrhea and consult your doctor if the diarrhea gets worse.

!### Dizziness Or Drowsiness

Lie down until the dizziness is gone, then get up slowly. Move slowly and
carefully; do not hurry. Get adequate rest. Drink plenty of water and other
fluids. Avoid intake of caffeine and its related products. If dizziness does not
improve or worsen, consult your doctor.

Headache

Drink ample amounts of water and avoid skipping meals. Get adequate rest. Try to
be relaxed and stress-free. Apply pain-relieving balm on your forehead if
necessary. Consult your doctor if the headache does not improve.

!### Nausea And Vomiting

Stick to simple meals while taking this medicine. Avoid eating oily, rich,
fried, or spicy foods. Do not lie down or sleep immediately after eating.
Consult your doctor if the nausea and vomiting does not improve.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to eat smaller meals more
frequently. Keep a heat pad on your stomach. Consult your doctor if the stomach
pain does not improve.

Warning & Precautions

!### Pregnancy

Monitoring requiredZOLIDPOS TABLET is not recommended for use in pregnant women unless clearly
advised by the doctor. Consult your doctor before taking ZOLIDPOS TABLET.

!### Breastfeeding

ContraindicatedZOLIDPOS TABLET is not recommended for use in breast-feeding women as it may
pass through the breast milk and could affect the baby. Consult your doctor
before taking ZOLIDPOS TABLET.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you experience dizziness or problems
with your vision after taking ZOLIDPOS TABLET.

!### Alcohol

Use with CautionAvoid consum
ZOLIDPOS TABLET.

!### Kidney

Use with CautionZOLIDPOS TABLET should be taken with caution in patients with kidney problems,
especially if the patient is on dialysis. Consult your doctor before taking
ZOLIDPOS TABLET.

!### Liver

Use with CautionZOLIDPOS TABLET should be taken with caution in patients with liver problems.
Consult your doctor before taking ZOLIDPOS TABLET.

!### Allergy

ContraindicatedDo not take ZOLIDPOS TABLET if you are allergic to Linezolid or any other
ingredients of this medicine.

!### Heart Disease

Use with CautionZOLIDPOS TABLET should be used with caution in patients with high blood
pressure. Consult your doctor before taking ZOLIDPOS TABLET.

!### Use In Pediatrics

ContraindicatedZOLIDPOS TABLET is not recommended for use in children and adolescents (under 18
years of age). Consult your child’s doctor for advice.

!### Use In Geriatrics

Use with CautionZOLIDPOS TABLET should be used with caution in elderly patients (aged 65 years
and above) due to the greater risk of developing blood dyscrasias (a condition
that affects the blood, bone marrow, or lymph tissue). Consult your doctor
before taking ZOLIDPOS TABLET.

Others

Before taking ZOLIDPOS TABLET, inform your doctor if you:

• have an overactive thyroid
• have an adrenal gland tumor (phaeochromocytoma) or carcinoid syndrome (tumors of the hormone system causing diarrhea, flushing of the skin, and wheezing)
• have mental disorders such as m
• bruise and bleed easily
• are anemic (low red blood cells)
• are prone to getting infections
• have a history of seizures
• have diarrhea
• have phenylketonuria (a rare genetic disorder that causes certain amino acids to build up in the body)
• have any scheduled surgery

Interactions

A. Drug-Drug interactions:

Before taking ZOLIDPOS TABLET, inform your doctor if you are taking any of the
following medicines:

• medicines used to manage a cold or flu (Ex. pseudoephedrine, phenylpropanolamine)
• medicines used to manage asthma (Ex. salbutamol, terbutaline, fenoterol)
• medicines used to manage depression (Ex. clomipramine, amitriptyline, doxepin, citalopram, dosulepin, fluoxetine, fluvoxamine, imipramine, lofepramine, paroxetine, and sertraline), monoamine oxidase inhibitors (MAOIs) (used to manage depression or Parkinson’s disease) (Ex. phenelzine, isocarboxazid, selegiline, and moclobemide)
• medicines used to manage migraines (Ex. sumatriptan, zolmitriptan)
• medicines used to manage sudden, severe allergic reactions (Ex. adrenaline (epinephrine))
• medicines that increase blood pressure (Ex. noradrenaline (norepinephrine), dopamine, and dobutamine)
• pethidine (used to manage moderate to severe pain)
• buspirone (used to manage anxiety disorders)
• warfarin (used to stop blood clotting)
• rifampicin (used to manage bacterial infections)

B. Drug-Food interactions:

Avoid eating large amounts of mature cheese, yeast extracts, or soy bean
extracts (Ex. soy sauce) while taking ZOLIDPOS TABLET, as it may react with a
substance called tyramine, which is naturally present in some foods, and cause
an increase in the blood pressure.

Overdosage:

If you or anyone else accidentally takes too much of ZOLIDPOS TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of an overdose
are vomiting, shaking, unsteadiness, or lack of coordination.

Synopsis

Drug	:	Linezolid
Pharmacological Category	:	Oxazolidinone antibiotic
Therapeutic Indication	:	Pneumonia, skin infections, and blood infections
Dosage Forms	:	Tablet, Dispersible Tablet, Injection, Infusion, Dry Syrup, Syrup, Oral suspension

More Information

Storage

• Keep ZOLIDPOS TABLET out of reach of children
• Store below 25°C

FAQs About ZOLIDPOS TABLET

Q: Can ZOLIDPOS TABLET be used in infants?

A: No, ZOLIDPOS TABLET is used for adults, and it is not recommended for
children and adolescents under 18 years of age. Your child’s doctor will select
a suitable alternative therapy for your child to manage the specific infection.

Q: Is ZOLIDPOS TABLET safe to use in patients with kidney problems?

A: ZOLIDPOS TABLET should be used with caution in patients with kidney problems,
especially if the patient is on dialysis. Your doctor may monitor your kidney
function test regularly to manage any unusual effects. Consult your doctor
before taking ZOLIDPOS TABLET.

Q: What if I forget to take a dose of ZOLIDPOS TABLET?

A: If you forget a dose of ZOLIDPOS TABLET, take it as soon as you remember.
However, if it is almost time for the next dose, skip the missed dose and take
the next scheduled dose at the prescribed time. Do not double the dose to make
up for the missed dose, as this may increase the chances of developing side
effects.

Q: Can I stop taking ZOLIDPOS TABLET on my own?

A: Continue taking ZOLIDPOS TABLET until your doctor tells you to stop it or
unless you experience any unwanted effects, worsening of your condition, or any
new symptoms. In such a case, contact your doctor right away. Do not stop taking
ZOLIDPOS TABLET because if you feel better. If you do so, your infection may get
worse again.

Q: Can ZOLIDPOS TABLET be used during pregnancy?

A: ZOLIDPOS TABLET is not recommended for use in pregnant women unless advised
by the doctor. Consult your doctor before taking ZOLIDPOS TABLET if you are
pregnant or planning to get pregnant.

Q: Can I face any problems after stopping ZOLIDPOS TABLET management?

A: ZOLIDPOS TABLET can cause some bacteria to multiply, which are normally
present in the bowel and normally harmless. Inform your doctor if you notice any
side effects occurring several weeks after stopping management with ZOLIDPOS
TABLET like severe stomach cramps, watery and severe diarrhea (which may be
bloody) or fever.

Q: What is ZOLIDPOS TABLET used for?

A: ZOLIDPOS TABLET is used to manage bacterial infections like pneumonia
(nosocomial and community-acquired pneumonia), some infections in or under the
skin (complicated skin and soft tissue infections), and blood infections.

Q: How does ZOLIDPOS TABLET work?

A: ZOLIDPOS TABLET works by binding to and inhibiting bacterial enzymes required
in DNA synthesis, thus interru
multiplication.

Q: What are the side effects of taking ZOLIDPOS TABLET?

A: The most common side effects of taking ZOLIDPOS TABLET are headache,
dizziness, nausea, vomiting, diarrhea, constipation, stomach pain, and
indigestion. Consult your doctor if any of the side effects worsen.

Q: Who should not take ZOLIDPOS TABLET?

A: Do not take ZOLIDPOS TABLET if you are allergic to Linezolid or any other
ingredients of this medicine.

Q: What precautions must be taken while using ZOLIDPOS TABLET?

A: Before taking ZOLIDPOS TABLET, inform your doctor if you have kidney
problems, especially if the patient is on dialysis, liver problems, high blood
pressure, overactive thyroid, adrenal gland tumor (phaeochromocytoma) or
carcinoid syndrome (tumors of the hormone system causing diarrhea, flushing of
the skin, and wheezing), mental disorders such as m
schizoaffective disorder, mental confusion, or other mental problems, bruise and
bleed easily, anemia (low red blood cells), or are prone to getting infections,
history of seizures, or have diarrhea, phenylketonuria (a rare genetic disorder
that causes certain amino acids to build up in the body), or scheduled for any
surgery.

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Liver Function Test (LFT)
• Kidney Function Test (KFT)
• Serum Electrolytes/ Electrolytes Profile
• Peripheral Smear Examination By Pathologist
• Culture & Sensitivity, Blood
• Health
• Health