NITRO Capsule 10's

Introduction About NITRO CAPSULE

NITRO CAPSULE contains Nitrofurantoin which belongs to the group of medicines
called Antibiotics. It is used in the management of urinary tract infections. It
is an infection that occurs in any part of the urinary system including bladder,
kidneys, ureters and urethra. It causes symptoms such as strong, continuous urge
to urinate, burning sensation while urinating, decreased flow in urine, cloudy
appearance of urine, blood in urine and pain in pelvic region, especially seen
among women.

Your doctor will regularly test to know how your lungs and liver are working.
NITRO CAPSULE may also interfere with urine tests for sugar, resulting in a
false positive result.

NITRO CAPSULE should be taken with caution in patients with lung or liver
disease, anaemia, diabetes (high blood sugar), any illness causing severe
weakness, electrolyte imbalance and vitamin B deficiency and recommended for use
in patients with severe kidney disease.

NITRO CAPSULE is not recommended for use in pregnant women at the stage of
labour or delivery because of the possibility that use at this stage may harm
the baby and should be used with caution in breast-feeding women.

This medicine is avoided for use in infants below 3 months of age. NITRO CAPSULE
should be used with caution in elderly patients.

The most common side effects of taking NITRO CAPSULE are nausea, vomiting, loss
of appetite and diarrhoea. Talk to your doctor if any of the side effects gets
worsen.

Uses Of NITRO CAPSULE

• Prevents and manage infections of the bladder, kidney and other parts of the urinary tract

How NITRO CAPSULE Works

NITRO CAPSULE effectively manages and manages urinary tract infection by killing
bacteria present in the urethra, bladder and/or kidneys. It mainly acts through
disru

How to use NITRO CAPSULE

Take NITRO CAPSULE as advised by your physician. Swallow NITRO CAPSULE with a
glass of water and do not crush or chew it. Your doctor will decide the correct
dose for you depending upon your age, body weight and the severity of infection.
NITRO CAPSULE should always be taken with food or milk for effective working and
to avoid stomach upset.

Side Effects Of NITRO CAPSULE

Common

• nausea
• vomiting
• loss of appetite
• diarrhoea

Uncommon

• acute pulmonary reaction syndrome (sudden onset of fever, chills, cough, body pain and shortness of breath)
• sub-acute pulmonary reactions (persistent dry cough, shortness of breath and fever)
• chronic pulmonary reaction (gradual onset of persistent dry cough and shortness of breath)

Rare

• loss of consciousness (collapse)
• anemia (fatigue, skin pallor, shortness of breath, dizziness or fast heartbeat due to damage to bone marrow causing deficiency of the red blood cells)
• signs of liver failure which may be fatal (yellow coloured skin and eyes along with stomach pain and swelling)

Stop taking NITRO CAPSULE and consult your doctor immediately if you experience
any of the following side effects:

• any sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching that affects your whole body
• fever, chills, cough and shortness of breath (reaction of lung with the medicine within a week or very slowly, mainly in elderly patients)
• yellowing of the skin or whites of the eyes (inflammation of the liver causing jaundice)
• changes in the sense of feeling and using muscles along with headache, extreme mood changes, confusion, weakness, blurred vision (due to affected nerves outside the spinal cord), which may be severe and permanent in some cases
• severe headaches (raised pressure in the skull)
• severe reduction in blood cells which results in weakness, bruising or more instance of infections
• blue or purple coloration of the skin (cyanosis causing low oxygen levels in the blood)
• signs of cutaneous vasculitis (fever, flu, abdominal pain, diarrhoea, blood in your stool, skin lesions and weakness)
• signs of autoimmune hepatitis (jaundice, fatigue, abdominal pain, joint pain and swelling)

How To Manage Side Effects

Nausea or vomiting:

Take NITRO CAPSULE with or just after meals. Stick to simple meals. Avoid eating
oil rich or spicy foods. If the symptom does not improve, contact your doctor.

Loss of appetite:

Eat when you feel hungry. Eat smaller meals frequently than usual. Snack only
when you're hungry. Eat a nutritious snack which is rich in calories and protein
such as dried fruit and nuts.

Diarrhoea:

Drink lots of fluids such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor. If the
symptom does not improve, contact your doctor.

Warning & Precautions

!### Pregnancy

NITRO CAPSULE is not recommended for use during labour or delivery because of
the possibility that use at this stage may harm the baby. It can be used with
caution in pregnant women or are planning to have a baby. However, consult your
doctor before taking NITRO CAPSULE.

!### Breastfeeding

NITRO CAPSULE should be used with caution for breastfeeding women and should be
avoided particularly for infant with known or suspected with erythrocyte enzyme
deficiency (including G6PD deficiency) as it may pass through the breast milk.
Consult your doctor before taking NITRO CAPSULE.

!### Driving and Using Machines

Do not drive or operate any machines if you feel dizzy or drowsy after taking
NITRO CAPSULE.

!### Alcohol

Avoid consum
you dizzier.

!### Kidney

NITRO CAPSULE is not recommended for use in patients with kidney disease that
severely affects the function of kidneys. It should be used with caution in
patients with kidney problems. Consult your doctor before taking NITRO CAPSULE.

!### Liver

NITRO CAPSULE should be taken with caution in patients with liver disease.
Consult your doctor before taking NITRO CAPSULE.

!### Allergy

Do not take NITRO CAPSULE if you are allergic to nitrofurantoin.

!### Lungs

NITRO CAPSULE should be taken with caution in patients with lung disease.
Consult your doctor before taking NITRO CAPSULE.

Others

NITRO CAPSULE is not recommended for use if you:

• are suffering from a blood disorder called porphyria (build-up of certain chemicals related to red blood cell that affects skin and nerve function)
• are deficient in an enzyme called g6pd (glucose-6-phosphate dehydrogenase) that causes in abdomen or back pain, fatigue, dark urine, pallor or yellow skin and eyes

Before taking NITRO CAPSULE, inform your doctor if you:

• have diabetes (high blood sugar)
• have anaemia (a decrease in red blood cells that causes pale skin, weakness and breathlessness)
• are suffering from any illness causing severe weakness
• lack of vitamin B (especially that results in fatigue, mouth sores, diarrhoea and depression)
• have abnormal electrolyte levels in your blood

Use in Pediatrics:

NITRO CAPSULE should be used with caution in children (under 6 years of age) and
infants above 3 months of age. It is not recommended for infants below three
months of age. However, consult your child’s doctor for advice.

Use in Geriatrics:

NITRO CAPSULE should be used with caution in elderly patients. Consult your
doctor before taking NITRO CAPSULE.

Interactions

A. Drug - Drug interactions:

Before taking NITRO CAPSULE, inform your doctor if you are taking any of the
following medicines:

• medicines used in the management of indigestion (such as antacids like magnesium trisilicate)
• medicines used to manage gout (Ex. probenecid or sulfinpyrazone)
• medicines which slow the passage of food through the stomach (Ex. atropine, hyoscine)
• medicines used to manage raised pressure in the eye known as glaucoma (such as carbonic anhydrase inhibitors Ex. acetazolamide)
• medicines which makes the urine less acidic (Ex. potassium citrate mixture)
• medicines used in the management of bacterial infections (Ex. ciprofloxacin, levofloxacin, moxifloxacin, gemifloxacin, besifloxacin)
• oral contrace
• typhoid vaccine (medicine given for the management of typhoid)

Overdosage:

If you or anyone else accidentally takes too much of NITRO CAPSULE, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose are
gastric irritation, nausea and vomiting.

Synopsis

Drug	:	Nitrofurantoin
Pharmacological Category	:	Antibiotic
Therapeutic Indication	:	Urinary tract infections
Dosage Forms	:	Tablet, Capsule

More Information

• Keep NITRO CAPSULE out of reach of children
• Store at room temperature

FAQs About NITRO CAPSULE

What happens if you don't take NITRO CAPSULE with food?

You should always take NITRO CAPSULE along with food or milk. Taking this
medicine along with food or milk makes it work more effectively against urinary
tract infections. This will also manage stomach upset and help the absor

What to do if I forget to take NITRO CAPSULE?

If you forget to take NITRO CAPSULE, don’t p
that day’s dose as usual. If you miss a whole day’s dose, then take normal dose
on the next day. Do not ever take a double dose to make up for the forgotten
dose. If you are not sure, consult your doctor immediately.

Does NITRO CAPSULE work for other infections?

No, NITRO CAPSULE belongs to a class of medication called antibiotics, which
works by killing bacteria. This medicine is mainly used in the management of
urinary tract infections. It does not work for cold, flu and other viral
infections.

How long does it take for NITRO CAPSULE to work?

NITRO CAPSULE should start working within three to five days, although it may
take up to a week for symptoms of urinary tract infections to clear. Be sure to
complete the full course of medication. That is the only way to ensure the
infection is completely gone.

Can NITRO CAPSULE be used in infants?

Yes, NITRO CAPSULE is generally used in children (under 6 years) and infants
above 3 months of age. It is not recommended for infants below three months.
Your child’s doctor will decide the correct dose or select a suitable
alternative therapy for your child.

Useful Diagnostic Tests

• Urine analysis
• Urine culture test