UNIAZ 16mg Tablet 10's

Introduction About UNIAZ 16MG TABLET

UNIAZ 16MG TABLET contains Azelnidipine which belongs to the group of medicines
called Antihypertensive agents. It is indicated for the management of stage-I
and stage-II hypertension. Hypertension is a condition in which force of the
blood is consistently high against the walls of the arteries which can increase
the risk of heart disease, kidney disease or stroke.

Stage I hypertension has systolic pressure ranging from 130 to 139 mm Hg or a
diastolic pressure ranging from 80 to 89 mm Hg. Stage II hypertension has
systolic pressure ranging from 140 mm Hg or higher or a diastolic pressure
ranging from 90 mm Hg or higher.

Along management with UNIAZ 16MG TABLET, your doctor might advise you to follow
certain lifestyle changes such as eating healthy diet, taking adequate sleep,
weight and stress management and avoid smoking or drinking alcohol.

Before taking UNIAZ 16MG TABLET inform your doctor if you have liver or kidney
diseases or any other medical conditions. Your doctor might ask you to take some
blood tests before initiating the management with UNIAZ 16MG TABLET to
understand the existing condition and for proper use of this medicine.

UNIAZ 16MG TABLET is not recommended for use in pregnant women or women who has
a possibility to conceive, and breast-feeding women. UNIAZ 16MG TABLET should be
used with caution in elderly patients.

Avoid consum
increase the risk of low blood pressure. The most common side effects of taking
UNIAZ 16MG TABLET are dizziness, light-headedness, nausea, constipation, fatigue
and stomach pain. Consult your doctor if any of the side effect worsens.

Uses Of UNIAZ 16MG TABLET

• Management of stage-I and stage-II hypertension

How UNIAZ 16MG TABLET Works

UNIAZ 16MG TABLET works by inhibiting the movement of calcium ions into both
vascular smooth muscle and cardiac muscle resulting in lower blood pressure by
relaxing the blood vessels and improving the flow of blood to the heart muscles.

How to use UNIAZ 16MG TABLET

Take UNIAZ 16MG TABLET as advised by your doctor. Swallow the medicine with a
glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration for you depending upon your age and general health
condition. Do not stop taking UNIAZ 16MG TABLET unless your doctor advises you
to stop.

Side Effects Of UNIAZ 16MG TABLET

Common

• rash, itching
• headache, heavy headed feeling, unsteady
• dizziness, light-headedness, drowsiness
• gastric distress, nausea, constipation, stomach pain, diarrhoea
• palpitation
• sensation of warmth, skin flushing on face portion
• fatigue, abnormal sensation
• frequent urination
• swelling
• numbness

Stop taking UNIAZ 16MG TABLET and inform your doctor immediately if you
experience any of the following side effects:

• jaundice and liver function failure (signs include pain in upper abdomen, abdominal swelling, tremors, disorientation, nausea, vomiting)
• cardiac arrest (signs include chest pain, palpitations, irregular heartbeat and shortness of breath)
• sinus block (heart rhythm disorder)
• slowed heart rate (bradycardia)

How To Manage Side Effects

!### Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and
drink plenty of water. Exercise more regularly. Consult your doctor if the
symptom does not improve.

!### Diarrhea

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Try to avoid taking any medicine on your own to manage
diarrhea and consult your doctor if the symptom gets worse.

!### Dizziness Or Drowsiness

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully,
do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid
coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets
worse.

Headache

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to
be relaxed and stress free. Apply pain relieving balm on your forehead if
necessary. Consult your doctor if the symptom does not improve.

!### Nausea And Vomiting

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried
or spicy foods. Do not lie down or sleep immediately after eating. Consult your
doctor if the symptom does not improve.

!### Stomach Pain

Try to rest and relax. Try to have smaller and frequent meals and have them
slowly. Keep a heat pad on your stomach. Ask for your doctor’s advice if stomach
pain doesn’t improve.

Warning & Precautions

!### Pregnancy

ContraindicatedUNIAZ 16MG TABLET is not recommended for use in pregnant women or women who has
a possibility to conceive because it may affect the developing baby resulting in
death of the fetus, reduced weight of the born child or extension in pregnancy
and delivery period. Consult your doctor before taking UNIAZ 16MG TABLET.

!### Breastfeeding

ContraindicatedUNIAZ 16MG TABLET is not recommended for use in breastfeeding women as it passes
through the breast milk. Consult your doctor before taking UNIAZ 16MG TABLET

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel giddy (whirling or spinning
sensation) after taking UNIAZ 16MG TABLET.

!### Kidney

Use with CautionUNIAZ 16MG TABLET should be taken with caution in patients with kidney problems.
Consult your doctor before taking it.

!### Liver

Use with CautionUNIAZ 16MG TABLET should be taken with caution in patients with liver problems.
Consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take UNIAZ 16MG TABLET if you are allergic to Azelnidipine or any other
ingredients of this medicine.

!### Use In Pediatrics

Consult your doctorSafety of UNIAZ 16MG TABLET in babies with low birth weight, newborn babies,
lactating babies, infants or small children is not yet established. Consult your
child’s doctor for advice.

!### Use In Geriatrics

Use with CautionUNIAZ 16MG TABLET should be used with caution in elderly patients (aged 65 years
and above). Consult your doctor before taking UNIAZ 16MG TABLET.

Interactions

A. Drug-Drug Interactions:

Before taking UNIAZ 16MG TABLET, inform your doctor if you are taking any of the
following medicines:

• medicines used to manage fungal infections (Ex. itraconazole, miconazole)
• medicines used to manage HIV infections (Ex. ritonavir, saquinavir, indinavir, delavirdine)
• cimetidine (used to manage stomach problems)
• imatinib (used to manage cancer)
• medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, rifampicin)
• cyclosporine (used to suppress the immune system to stop organ rejection after transplant)
• medicines used to manage anxiety, insomnia (Ex. diazepam, midazolam, triazolam, tandospirone)
• phenytoin, phenobarbital (used to manage seizures)
• medicines used to inhibit the occurence pregnancy (Ex. estradiol, norethindrone)
• digoxin (used to manage heart diseases)
• simvastatin (used to control high cholesterol levels)

B. Drug-Food Interactions:

Avoid consum
increase the risk of low blood pressure.

Overdosage:

If you or anyone else accidentally take too much of UNIAZ 16MG TABLET, consult
your doctor immediately or visit the nearby hospital. Overdosage symptoms of
UNIAZ 16MG TABLET are abnormally low blood pressure and reflex tachycardia
(rapid heartbeat).

Synopsis

Drug	:	Azelnidipine
Pharmacological Category	:	Calcium channel blocker
Therapeutic Indication	:	Stage-I and Stage-II hypertension
Dosage Forms	:	Tablet

More Information

Storage

• Keep UNIAZ 16MG TABLET out of reach of children
• Store UNIAZ 16MG TABLET at room temperature

FAQs About UNIAZ 16MG TABLET

Q: What is [GBNKEYORD] and why is it prescribed?

A: UNIAZ 16MG TABLET contains Azelnidipine which belongs to the group of
medicines called Antihypertensive agents. It is indicated for the management of
stage-I and stage-II hypertension. Stage I hypertension has systolic pressure
ranging from 130 to 139 mm Hg or a diastolic pressure ranging from 80 to 89 mm
Hg. Stage II hypertension has systolic pressure ranging from 140 mm Hg or higher
or a diastolic pressure ranging from 90 mm Hg or higher.

Q: Can UNIAZ 16MG TABLET affect my ability to drive?

A: UNIAZ 16MG TABLET has an antihypertensive effect (low blood pressure may
result in dizziness or giddiness). Do not drive or operate any machines if you
feel giddy (whirling or spinning sensation) after taking UNIAZ 16MG TABLET. You
can resume with your activities once you feel normal again. Consult your doctor
for advice.

Q: Is UNIAZ 16MG TABLET safe to use in pregnant women?

A: UNIAZ 16MG TABLET is not recommended for use in pregnant women or women who
has a possibility to conceive because it may affect the developing baby
resulting in death of the fetus, reduced weight of the born child or extension
in pregnancy and delivery period. Consult your doctor before taking it.

Q: What if I forget to take a dose of UNIAZ 16MG TABLET?

A: If you forget to take a dose of UNIAZ 16MG TABLET, take it as soon as you
remember. However, omit the missed dose if it is almost time for the next dose.
Do not take UNIAZ 16MG TABLET twice to make up for the forgotten dose.

Q: Is UNIAZ 16MG TABLET safe to use in patients with kidney problems?

A: UNIAZ 16MG TABLET should be taken with caution in patients with kidney
problems. Your doctor may adjust the dose based on functioning of the kidney.
Consult your doctor before taking UNIAZ 16MG TABLET.

Useful Diagnostic Tests

• Cardia Risk Profile