Trapex Injection 1ml

Introduction About TRAPEX INJECTION

TRAPEX INJECTION contains Lorazepam, which belongs to the group of medicines
called Antianxiety agents. It is used to relieve anxiety, muscle tension, and
excitement or agitation and controls convulsions (fits). TRAPEX INJECTION can
also be used as a pre-medication before any operation or prolonged
investigations.

Anxiety is an emotion characterized by feelings of tension, worried and
intrusive thoughts, and physical changes like increased blood pressure,
sweating, trembling and dizziness. Your doctor might ask you to make some
lifestyle changes, such as having healthy sleeping and eating habits and
managing stress through meditation.

TRAPEX INJECTION is not recommended for use in patients having lung or liver
diseases, myasthenia gravis (very weak or tired muscles), and sleep apnoea
(breathing problems while sleeping). It should be used with caution in patients
who have kidney diseases, habitual excessive use of drugs or alcohol,
personality disorders, depression, history of psychotic illness, history of
convulsions, and glaucoma (increased pressure in the eye).

TRAPEX INJECTION must be used with caution in pregnant women. TRAPEX INJECTION
is not recommended for use in breastfeeding women. TRAPEX INJECTION should be
used with caution in elderly patients. TRAPEX INJECTION should not be used in
children below 12 years of age.

The most common side effects of receiving this medicine are sedation
(sleepiness), drowsiness, lack of energy, confusion dizziness, muscle weakness,
or depression. Consult your doctor if any of your symptoms get worse or persist.

Uses Of TRAPEX INJECTION

Relieves:

• anxiety
• muscle tension
• excitement or agitation

Controls:

• convulsions (fits)

Used as a pre-medication:

• surgery
• prolonged investigations

How TRAPEX INJECTION Works

TRAPEX INJECTION acts on certain centres located in the central nervous system.
It aids in increasing the levels of a calming chemical in the brain which can
make you feel calm, relaxed and relieved.

How to use TRAPEX INJECTION

TRAPEX INJECTION will be given to you only by a doctor or a nurse into a vein or
a muscle as an intravenous or intramuscular infusion respectively. Your doctor
will decide the correct dose and duration for you depending on your age, disease
condition and body weight.

Side Effects Of TRAPEX INJECTION

Common

• sedation (sleepiness)
• drowsiness
• tiredness
• confusion
• dizziness
• muscle weakness
• lack of energy
• depression
• unmasking of depression (revealing the signs of depression which were hidden)
• lack of muscle coordination

Uncommon

• nausea
• change in libido
• impotence
• decreased orgasm

Rare

Stop receiving TRAPEX INJECTION and inform your doctor immediately if you
experience any of the following side effects:

• suicidal thoughts and feelings
• changes in mental state
• anaphylaxis which is a severe allergic reaction characterised by swelling of the tongue or throat, throat closing, shortness of breath, swelling of hands and feet
• angioedema which causes swelling of the throat and face
• breathing problems
• signs of jaundice which include yellowing of skin and whites of the eyes

How To Manage Side Effects

Nausea:

Receive this medicine with, or just after meals. Stick to simple meals. Avoid
eating rich or spicy food. Ask for your doctor’s advice if your symptoms do not
improve.

Drowsiness:

Take adequate sleep. Do not involve in rigorous activities. Do not interfere
with your sleep cycle. Ask for your doctor’s advice if your symptoms do not
improve.

Warning & Precautions

!### Pregnancy

TRAPEX INJECTION should be used with caution in pregnant women. Consult with
your doctor before receiving it.

!### Breastfeeding

TRAPEX INJECTION should be used with caution in breastfeeding women as it may
pass through breast milk. Consult your doctor before receiving it.

!### Driving and Using Machines

Do not drive or use machinery if you feel sleepy or dizzy after receiving TRAPEX
INJECTION.

!### Alcohol

Avoid the use of alcohol for at least 24 to 48 hours after receiving TRAPEX
INJECTION.

!### Kidney

TRAPEX INJECTION should be used with caution in patients with kidney diseases
such as impaired renal function. Your doctor might prescribe lower doses for
you. Consult your doctor before receiving TRAPEX INJECTION.

!### Liver

TRAPEX INJECTION is not recommended for use in patients with liver diseases such
as severe hepatic impairment. Lower doses may be used in patients who have mild
to moderate hepatic insufficiency. Consult your doctor before receiving TRAPEX
INJECTION.

!### Allergy

Before receiving TRAPEX INJECTION, inform your doctor if you are allergic to
Lorazepam.

!### Lungs

TRAPEX INJECTION is not recommended for use in patients having lung diseases
such as severe breathing or chest problems. It should be used with caution in
patients having other breathing issues. Consult with your doctor before
receiving TRAPEX INJECTION.

Others

TRAPEX INJECTION is not recommended for use in patients who have:

• myasthenia gravis (very tired or weak muscles)
• sleep apnoea (breathing problems while sleeping)

Before receiving TRAPEX INJECTION, inform your doctor if you:

• have or had habitual excessive use of drugs or alcohol
• have personality disorders
• have or had depression
• have a history of psychotic illness
• have a history of convulsions
• have glaucoma (increased pressure within the eye)
• are weak
• have lactose intolerance

Use in paediatrics:

TRAPEX INJECTION is not recommended for use in children below 12 years of age.
Consult with your doctor before receiving TRAPEX INJECTION.

Use in geriatrics:

TRAPEX INJECTION should be used with caution in elderly patients. Your doctor
might prescribe you with lower doses. Consult with your doctor before receiving
TRAPEX INJECTION.

Interactions

A. Drug-Drug Interactions:

Inform your physician if you are taking any of the following drugs before
receiving TRAPEX INJECTION:

• sedatives such as zolpidem, eszopiclone, anti-anxiety drugs such as citalopram, antidepressants such as paroxetine, sertraline, chlorpromazine, clozapine and haloperidol (used to manage depression, anxiety, mood disorders, sleep disturbances)
• methadone, opioids such as codeine, oxymorphone (used to manage severe pain)
• sodium valproate (used to manage epilepsy)
• antihistamines such as cetirizine, and loratadine (used to manage allergies)
• theophylline, aminophylline (used to manage respiratory diseases)
• probenecid (used to manage gout)
• scopolamine (used in motion sickness and surgeries)

Overdosage:

TRAPEX INJECTION will be administered to you only by a doctor or a nurse in a
hospital, so it is unlikely to receive an overdose. However, consult your doctor
or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Lorazepam
Pharmacological Category	:	Benzodiazepines
Therapeutic Indication	:	Anxiety, Sleep disturbances, Surgeries
Dosage Forms	:	Tablet, Injection

More Information

• Keep TRAPEX INJECTION out of reach from children
• Store at room temperature below 25°C

FAQs About TRAPEX INJECTION

What is TRAPEX INJECTION and why is it prescribed?

TRAPEX INJECTION contains Lorazepam, which belongs to the group of medicines
called Antianxiety agents. It is used to relieve anxiety, muscle tension, and
excitement or agitation and controls convulsions (fits). TRAPEX INJECTION can
also be used as a pre-medication before any operation or prolonged
investigation.

Can I stop receiving TRAPEX INJECTION if I start to feel better?

You must not stop receiving TRAPEX INJECTION until and unless your doctor asks
you to. TRAPEX INJECTION should be gradually stopped. On stopping TRAPEX
INJECTION you may experience headaches, muscle or stomach pains, tension,
depression, anxiety, restlessness, sweating, sleep problems, confusion, or
irritability. If at all you wish to discontinue the medicine, ask for your
doctor’s advice.

Does TRAPEX INJECTION affects my ability to drive?

TRAPEX INJECTION may make you sleepy or dizzy. Do not drive or use machinery for
24 to 48 hours if you feel sleepy or dizzy after receiving TRAPEX INJECTION. You
can resume your activities once you feel normal again.

Can TRAPEX INJECTION be used in children?

TRAPEX INJECTION is not recommended for use in children below 12 years of age.
Also, it is not recommended for use in children for anxiety and sleeping
problems. Consult with your doctor before using it for your child.

Is TRAPEX INJECTION safe to use in elderly patients?

TRAPEX INJECTION should be used with caution in elderly patients. Your doctor
might prescribe you with lower doses. Consult with your doctor before receiving
TRAPEX INJECTION.

Can TRAPEX INJECTION be given to pregnant and breastfeeding women?

TRAPEX INJECTION should be used with caution in pregnant women as it may cause
damage to the foetus and also in breastfeeding women as it may pass through
breast milk. Consult your doctor before receiving TRAPEX INJECTION.