Tazotene 0.10% Gel 15gm

Introduction About TAZOTENE 0.10% GEL

TAZOTENE 0.10% GEL contains Tazarotene which belongs to the group of medicines
called Retinoids. It is used to topically manage plaque psoriasis and acne
vulgaris. Plaque psoriasis is a skin disease that causes dry, itchy, raised skin
patches (plaques) covered with scales. Acne vulgarisis a common, usually
self-limiting disease that causes inflammation of the sebaceous follicles of the
face and upper body.

Before using TAZOTENE 0.10% GEL, inform your doctor if you have liver, kidney,
or heart problems, eczema, or other skin problems. TAZOTENE 0.10% GEL is not
recommended for use among pregnant women. TAZOTENE 0.10% GEL should be used with
caution in breastfeeding women. Consult your doctor before using it.

It is not known if TAZOTENE 0.10% GEL is safe and effective for use in children
and adolescents under 12 years of age. TAZOTENE 0.10% GEL for the management of
acne has not been clinically evaluated in elderly patients (over 65 years).

The most common side effects of using TAZOTENE 0.10% GEL are itching, burning,
redness, worsening of psoriasis, irritation, skin pain, peeling, and dry skin.
Contact your doctor if any of the symptoms worsen.

Uses Of TAZOTENE 0.10% GEL

• Topically manage plaque psoriasis and acne vulgaris

How TAZOTENE 0.10% GEL Works

TAZOTENE 0.10% GEL is converted to its active form, tazarotenic acid, that binds
to all three members of the retinoic acid receptor (RAR) family (RARa, RARβ, and
RARγ) and may modify gene expression.

How to use TAZOTENE 0.10% GEL

Apply TAZOTENE 0.10% GEL as advised by your physician. It is for external use
only. Your doctor will decide the correct dose and duration for you depending
upon your age, body weight and disease condition.

Side Effects Of TAZOTENE 0.10% GEL

Common

• itching
• burning
• redness
• worsening of psoriasis
• irritation
• pain
• peeling
• dryness

Stop using TAZOTENE 0.10% GEL and contact your doctor immediately if you
experience any of the following side effects:

• skin irritation and allergic reactions (hives, itching, burning, redness, blistering, or peeling of your skin)
• sunlight sensitivity and risk of sunburn

Warning & Precautions

!### Pregnancy

ContraindicatedTAZOTENE 0.10% GEL is not recommended for use in pregnancy as it may cause birth
defects. Consult your doctor before using it.

!### Breastfeeding

Use with CautionTAZOTENE 0.10% GEL should be used with caution in breastfeeding women as it is
not known if it passes into breast milk. Consult your doctor before using it.

!### Allergy

ContraindicatedDo not use TAZOTENE 0.10% GEL if you are allergic to Tazarotene.

!### Use In Pediatrics

Consult your doctorIt is not known if TAZOTENE 0.10% GEL is safe and effective in children and
adolescents (under 12 years of age). Consult your doctor before using it.

!### Use In Geriatrics

Consult your doctorTAZOTENE 0.10% GEL for the management of acne has not been clinically evaluated
in elderly patients (over 65 years). Consult your doctor before using it.

Others

Before using TAZOTENE 0.10% GEL, inform your doctor if you:

• eczema or other skin problems

Interactions

A. Drug-Drug interactions:

Before using TAZOTENE 0.10% GEL, inform your doctor if you are using, have used,
or might use any other medicine, including prescri
herbal medicine.

Overdosage:

If you or anyone else accidentally use too much of TAZOTENE 0.10% GEL, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose
include marked redness, peeling, or discomfort.

Synopsis

Drug	:	Tazarotene
Pharmacological Category	:	Acetylenic retinoid
Therapeutic Indication	:	Plaque psoriasis, acne vulgaris
Dosage Forms	:	Cream, Gel

More Information

• Keep TAZOTENE 0.10% GEL out of reach of children
• Store between 20-25°C

FAQs About TAZOTENE 0.10% GEL

Q: Is TAZOTENE 0.10% GEL safe to use during pregnancy?

A: TAZOTENE 0.10% GEL may cause birth defects if used in pregnancy. Women must
not be pregnant when they start using or during management with this medicine.
For women who get pregnant, your doctor will order a pregnancy test within 2
weeks before you begin management with TAZOTENE 0.10% GEL to be sure that you
are not pregnant.

Get safety advice from your doctor for using TAZOTENE 0.10% GEL during a normal
menstrual period. Discuss with your doctor about birth control o
be used during the management. Stop using it and tell your doctor immediately if
you become pregnant while using this medicine.

Q: What if TAZOTENE 0.10% GEL accidentally gets into my eye?

A: Avoidgetting TAZOTENE 0.10% GEL in your eyes or eyelids. If it gets in or
near your eyes, rinse them thoroughly with water. Call your doctor if you have
persistent eye irritation. Wash your hands after applying TAZOTENE 0.10% GEL.

Q: What should I avoid while using TAZOTENE 0.10% GEL?

A: While using TAZOTENE 0.10% GEL, avoid exposure to sunlight, including
sunlamps. Use sunscreen and cover your skin if you have to be in the sun. Avoid
using cosmetics or topical medicines that may make your skin more sensitive to
the sun or dry. Avoid using it on unaffected skin or skin with eczema, as it may
cause severe irritation.

Q: What if I accidentally swallow TAZOTENE 0.10% GEL?

A: Avoidgetting TAZOTENE 0.10% GEL in your mouth. If you or anyone else swallows
it, call your doctor or go to the nearest hospital immediately.

Q: Can TAZOTENE 0.10% GEL cause itching?

A: Yes. TAZOTENE 0.10% GEL may cause itching. In such a case, pat your skin
instead of scratching it and hold something cool, like a damp towel, on it. Wear
loose cotton clothes. Consult your doctor if you have persistent itching.

Useful Diagnostic Tests

• Skin biopsy