Nasocobal 250Mcg Nasal Spray 2.3ml

Introduction About NASOCOBAL 250MCG NASAL SPRAY

NASOCOBAL 250MCG NASAL SPRAY contains Mecobalamin which belongs to the group of
medicines called Vitamins. NASOCOBAL 250MCG NASAL SPRAY is used as a maintenance
therapy in adult patients with pernicious anaemia who are in remission status
(following intramuscular vitamin B12 therapy) without the involvement of nervous
system.

NASOCOBAL 250MCG NASAL SPRAY is also used to manage adult patients with vitamin
B12 deficiency that occurred due to dietary, drug-induced, and/or malabsor
factors. It is also indicated for use to manage vitamin B12 deficiency in adult
patients with vitamin B12 requirements.

NASOCOBAL 250MCG NASAL SPRAY is not recommended for use in patients allergic to
mecobalamin, cobalt, and/or vitamin B12. It is also not recommended for use in
patients suffering from severe Leber hereditary o
form of vision loss), and/or runny nose/nasal blockage.

Before using NASOCOBAL 250MCG NASAL SPRAY, inform your doctor if you have early
Leber’s disease, low levels of folate/iron in your blood (associated with signs
such as extreme tiredness, sore/red tongue, muscle weakness), kidney problems
(such as chronic renal disease), and/or liver problems.

NASOCOBAL 250MCG NASAL SPRAY should be used with caution during pregnancy only
if it is clearly necessary. It is also used with caution in breastfeeding women
and children & adolescents (aged below 18 years).  The medicine is also advised
to be used with caution in elderly patients (aged above 65 years) after
consulting the doctor.

The most common side effects of using NASOCOBAL 250MCG NASAL SPRAY are headache,
weakness, inflamed/swollen tongue, burning/prickling sensation in arms/legs,
nausea, and/or stuffy nose. Consult your doctor if any of these side effects
worsen.

Uses Of NASOCOBAL 250MCG NASAL SPRAY

• As a maintenance therapy in adult patients with pernicious anaemia who are in remission status (following intramuscular vitamin B12 therapy) without the involvement of the nervous system
• Manage adult patients with vitamin B12 deficiency that occurred due to dietary, drug-induced, and/or malabsor
• Prevents vitamin B12 deficiency in adult patients with vitamin B12 requirements

How NASOCOBAL 250MCG NASAL SPRAY Works

NASOCOBAL 250MCG NASAL SPRAY works by increasing and restoring vitamin B12
levels in the blood thus promoting blood cell production and managing the
deficiency of vitamin B12 and the occurrence of pernicious anaemia in affected
individuals.

How to use NASOCOBAL 250MCG NASAL SPRAY

Use NASOCOBAL 250MCG NASAL SPRAY as advised by your physician. It is for
intranasal use only. Gently, blow your nose to clear both nostrils. Hold
NASOCOBAL 250MCG NASAL SPRAY with your thumb on the bottom with your index &
middle finger on either side of the nozzle and gently close one side of your
nostril with your other index finger. Insert the nozzle into the open nostril
about half an inch or as far as it feels comfortable and tilt your head slightly
forward while nozzle insertion. Breathe in gently (from your nostril) and close
your mouth. Press the plunger firmly upwards with your thumb and remove the
nozzle. Keep your head firm for 10 to 20 seconds while gently breathing in
through your nose and breathing out through your mouth. Your doctor will decide
the correct dose and duration for you depending on your age, body weight and
disease condition.

Side Effects Of NASOCOBAL 250MCG NASAL SPRAY

Common

• infection
• inflamed/swollen tongue
• headache, weakness
• burning/prickling sensation in arms/legs
• nausea
• stuffy nose

How To Manage Side Effects

Headache:

If NASOCOBAL 250MCG NASAL SPRAY causes a headache, then take rest and drink
plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a
painkiller. Headaches should usually go away after the first week of taking
NASOCOBAL 250MCG NASAL SPRAY. If it lasts more than a week or is severe, inform
your doctor.

Nausea:

Take NASOCOBAL 250MCG NASAL SPRAY with or just after a meal. Stick to simple
meals. Avoid eating oil-rich or spicy foods, sugary snacks and drinks. Avoid
drinking too much liquid along with your meals, drink slowly in between meals.
Talk with your doctor if the condition worsens.

Warning & Precautions

!### Pregnancy

NASOCOBAL 250MCG NASAL SPRAY should be used with caution in pregnant women only
if it is clearly necessary. Consult your doctor before using NASOCOBAL 250MCG
NASAL SPRAY.

!### Breastfeeding

NASOCOBAL 250MCG NASAL SPRAY should be used with caution in breastfeeding women.
Consult your doctor before using the medicine.

!### Kidney

NASOCOBAL 250MCG NASAL SPRAY should be used with caution in patients with kidney
problems such as chronic kidney disease. Consult your doctor before using
NASOCOBAL 250MCG NASAL SPRAY.

!### Liver

NASOCOBAL 250MCG NASAL SPRAY should be used with caution in patients with liver
problems. Consult your doctor before using NASOCOBAL 250MCG NASAL SPRAY.

!### Allergy

Do not use NASOCOBAL 250MCG NASAL SPRAY if you are allergic to mecobalamin,
cobalt, vitamin B12, and/or any other ingredients of this medicine.

Others

NASOCOBAL 250MCG NASAL SPRAY is not recommended for use if you:

• suffer from severe Leber hereditary o
• are suffering from a runny nose or nasal blockage

Before using NASOCOBAL 250MCG NASAL SPRAY, inform your doctor if you:

• suffer from early Leber’s disease
• have signs of low levels of folate/iron in the blood such as extreme tiredness, sore/red tongue, muscle weakness, and/or burning/prickling sensation in arms/legs.

Use in Paediatrics:

NASOCOBAL 250MCG NASAL SPRAY is advised to be used with caution in children and
adolescents (aged below 18 years). Consult your doctor before using the
medicine.

Use in Geriatrics:

NASOCOBAL 250MCG NASAL SPRAY should be used with caution in elderly patients
(aged above 65-years). Consult your doctor before using the medicine.

Interactions

A. Drug - Drug interactions:

Before using NASOCOBAL 250MCG NASAL SPRAY, inform your doctor if you are taking
any of the following medicine:

• chloramphenicol (used to manage bacterial infections).

B. Drug - Food interaction:

Avoid taking hot foods/liquids while administering NASOCOBAL 250MCG NASAL SPRAY
since it may cause nasal secretions and reduce the effect of the medicine. To
manage such effects, administer the medicine one before/after ingesting hot
foods/liquids.

Overdosage:

If you or anyone else accidentally administers too much of NASOCOBAL 250MCG
NASAL SPRAY, consult your doctor immediately or visit the nearby hospital to
manage the overdose symptoms.

Synopsis

Drug	:	Mecobalamin
Pharmacological Category	:	Vitamin B12
Therapeutic Indication	:	Diabetic neuropathy, Peripheral neuropathy, Megaloblastic anaemia, General weakness, Sciatica pain, back pain
Dosage Forms	:	Tablet, Oral disintegrating strip, Injection, Nasal spray

More Information

• Keep NASOCOBAL 250MCG NASAL SPRAY out of reach of children
• Do not store NASOCOBAL 250MCG NASAL SPRAY above 30°C

FAQs About NASOCOBAL 250MCG NASAL SPRAY

What is NASOCOBAL 250MCG NASAL SPRAY used for?

NASOCOBAL 250MCG NASAL SPRAY is used as a maintenance therapy in adult patients
with pernicious anaemia who are in remission status following intramuscular
vitamin B12 therapy.  It is also used to manage adult patients with vitamin B12
deficiency that occurs due to dietary, drug-induced, and/or malabsor
factors. It is also indicated for use to manage vitamin B12 deficiency in adult
patients with vitamin B12 requirements.

How NASOCOBAL 250MCG NASAL SPRAY be used?

Use NASOCOBAL 250MCG NASAL SPRAY as advised by your physician. It is for
intranasal use only. Gently, blow your nose to clear both nostrils and hold
NASOCOBAL 250MCG NASAL SPRAY with your thumb on the bottom with your index &
middle finger on either side of the nozzle. Gently, close one side of your
nostril with your other index finger and insert the nozzle into the open nostril
about half an inch or as far as it feels comfortable keeping your head slightly
forward. Breathe in gently (from your nostril) and close your mouth. Press the
plunger firmly upwards with your thumb and remove the nozzle. Keep your head
firm for 10 to 20 seconds while gently breathing in through your nose and
breathing out through your mouth. Your doctor will decide the correct dose and
duration for you depending on your age, body weight and disease condition.

What are the side effects of NASOCOBAL 250MCG NASAL SPRAY?

The most common side effects of using NASOCOBAL 250MCG NASAL SPRAY are headache,
weakness, inflamed/swollen tongue, burning/prickling sensation in arms/legs,
nausea, and/or stuffy nose. Consult your doctor if any of these side effects
worsen.

How NASOCOBAL 250MCG NASAL SPRAY works?

NASOCOBAL 250MCG NASAL SPRAY works by increasing and restoring vitamin B12
levels in the blood thus promoting blood cell production and managing the
deficiency of vitamin B12 and the occurrence of pernicious anaemia in affected
individuals.

Does NASOCOBAL 250MCG NASAL SPRAY cause headaches?

Yes, NASOCOBAL 250MCG NASAL SPRAY causes headaches as it is the commonest side
effect associated with the use of NASOCOBAL 250MCG NASAL SPRAY. If such side
effects are experienced after receiving the medicine, then try to take rest and
drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to
recommend a painkiller. Headaches should usually go away after the first week of
receiving NASOCOBAL 250MCG NASAL SPRAY. If it lasts more than a week or is
severe, then inform your doctor.

Useful Diagnostic Tests

• Complete blood count
• MMA test