LOPITAR 50 Tablet 10's

Introduction About LOPITAR 50 TABLET

LOPITAR 50 TABLET is used to manage mild to moderate hypertension. It also used
to manage hypertensive patients with left ventricular hypertrophy and
nephropathy in type 2 diabetic patients. It contains Losartan which belongs to
the group of medicines called Antihypertensive agents. It blocks the effects of
Angiotensin II (substance produced in your body which causes narrowing of blood
vessels), which leads to relaxation of blood vessels resulting in low blood
pressure in affected individuals.

LOPITAR 50 TABLET is not recommended for use in patients allergic to losartan.
It is also not recommended for use in patients with severely impaired liver
function and kidney function. Before taking the medicine, inform your doctor if
you have a history of angioedema and/or suffering from excessive
vomiting/diarrhoea, primary hyperaldosteronism kidney problems. LOPITAR 50
TABLET is not recommended for use in early pregnancy and must not be taken when
a woman is more than 3 months pregnant since it may cause serious harm to the
baby if used after 3-months of pregnancy. It is not known whether the medicine
is excreted in human milk, hence consult your doctor before taking the medicine.

It is not recommended for use in children under 6 years of age. The most common
side effects are dizziness, general weakness, tiredness, low blood sugar,
changes in kidney function (associated with signs such as decreased urine
output, edema, shortness of breath) and/or anaemia. Consult your doctor if any
of these symptoms worsens.

Uses Of LOPITAR 50 TABLET

It is used to manage:

• mild to moderate hypertension
• hypertensive patients with left ventricular hypertrophy
• nephropathy in type 2 diabetic patients

How LOPITAR 50 TABLET Works

LOPITAR 50 TABLET blocks the effects of Angiotensin II (substance produced in
your body which causes narrowing of blood vessels), which leads to relaxation of
blood vessels resulting in low blood pressure in affected individuals.

How to use LOPITAR 50 TABLET

• Take LOPITAR 50 TABLET as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of LOPITAR 50 TABLET

Common Side Effects of LOPITAR 50 TABLET:

• dizziness, general weakness, tiredness
• low blood pressure orthostatic hypotension
• signs of low blood sugar such as fast heartbeat, shaking, sweating and/or hunger
• signs of changes in kidney function such as decreased urine output, oedema, shortness of breath
• abdominal pain, constipation, diarrhoea

Stop taking LOPITAR 50 TABLET and contact your doctor immediately if you
experience any of the following side effects:

• signs of severe allergic reactions such as rash, itching, swelling of the face, lips, mouth/throat that may cause difficulty in swallowing or breathing

Warning & Precautions

!### Pregnancy

ContraindicatedLOPITAR 50 TABLET is not recommended in early pregnancy and must not be taken
when more than 3 months pregnant, as it may cause serious harm to the baby if
used after 3 months of pregnancy.

!### Breastfeeding

Consult your doctorIt is not known whether the medicine is excreted in human milk, hence consult
your doctor before taking the medicine.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel dizzy or drowsy after taking
LOPITAR 50 TABLET.

!### Kidney

Consult your doctorLOPITAR 50 TABLET is not recommended for use in patients with impaired kidney
function. It should be taken with caution in patients with narrowing of blood
vessels to one or both the kidneys and in patients who had recently received
kidney transplant.

!### Liver

Consult your doctorLOPITAR 50 TABLET is not recommended for use in patients with severely impaired
liver function. It should be used with caution in patients having impaired liver
function.

!### Allergy

ContraindicatedDo not take LOPITAR 50 TABLET if you are allergic to Losartan and/or any other
ingredients of this medicine.

!### Heart Disease

Use with CautionLOPITAR 50 TABLET should be taken with caution in patients having heart failure,
problems in heart valve and heart muscle, cardiac arrythmia (irregular and fast
heartbeat), coronary heart disease.

!### Use In Pediatrics

Consult your doctorLOPITAR 50 TABLET is not recommended for use in children under 6 years of age
and also in children suffering from kidney and/or liver problems. The medicine
is recommended for used in children and adolescents (aged 6 to 18 years) after
consulting the doctor.

!### Use In Geriatrics

Use with CautionLOPITAR 50 TABLET should be used with caution in patients (aged above 75 years).

Others

LOPITAR 50 TABLET is not recommended for use if you have:

• diabetes and managed with blood pressure lowering medicine containing aliskiren

Before taking LOPITAR 50 TABLET, inform your doctor if you:

• have a history of angioedema (swelling of the face, lips, throat and/or tongue)
• suffer from excessive vomiting/diarrhoea leading to extreme loss of fluid and/or salt in your body
• suffer from primary hyperaldosteronism (a syndrome associated with increased secretion of aldosterone hormone)
• suffer from cerebrovascular disease (caused by a reduced blood circulation to the brain)
• salt-restricted diet

Interactions

A. Drug-Drug Interactions:

Before taking LOPITAR 50 TABLET, inform your doctor if you are taking any of the
following medicine:

• diuretics (Ex. furosemide, bumet
• potassium-sparing diuretics (Ex. amiloride, triamterene, spironolactone)
• angiotensin converting enzyme inhibitors (Ex. enalapril, lisinopril, ramipril)
• aliskiren
• beta blockers (Ex. atenolol, propranolol, carvedilol)
• Anticoagulants (Ex. heparin)
• Antibiotics (Ex. trimethoprim)
• potassium supplements and potassium-containing salt substitutes
• antidepressants (Ex. citalopram, fluoxetine, paroxetine)
• antipsychotic agents (Ex. haloperidol, thioridazine)
• skeletal muscle relaxants (Ex. baclofen)
• cytoprotectants (Ex. amifostine)
• cox-2 inhibitors (Ex. meloxicam, etodolac)
• Antim

Overdosage:

If you or anyone else accidentally take too much of LOPITAR 50 TABLET, consult
your doctor immediately or visit the nearby hospital. The most common symptoms
of overdose are low blood pressure, fast heartbeat and slow heartbeat.

Synopsis

Drug	:	Losartan
Pharmacological Category	:	Angiotensin II receptor antagonists
Therapeutic Indication	:	Hypertension, Hypertensive patients with left ventricular hypertrophy, Neuropathy in type 2 diabetic patient
Dosage Forms	:	Tablet

More Information

FAQs About LOPITAR 50 TABLET

Q: What is LOPITAR 50 TABLET used for?

A: LOPITAR 50 TABLET is primarily used to manage high blood pressure
(hypertension). It is also prescribed to protect the kidneys in people with
diabetes and to reduce the risk of stroke in individuals with heart disease. By
lowering blood pressure, Losartan helps reduce complications such as heart
attacks, strokes, and kidney damage.

Q: How does LOPITAR 50 TABLET works?

A: LOPITAR 50 TABLET belongs to a class of drugs called angiotensin II receptor
blockers (ARBs). It works by relaxing blood vessels, making it easier for blood
to flow. It blocks the action of angiotensin II, a natural substance that
tightens blood vessels and increases blood pressure. By preventing this
tightening, Losartan lowers blood pressure and reduces strain on the heart.

Q: What is the best time to take LOPITAR 50 TABLET?

A: LOPITAR 50 TABLET is usually taken once a day, with or without food. It is
often recommended to take it at the same time each day to maintain consistent
blood levels. Some people prefer taking it in the morning to avoid nighttime
urination, while others may take it at night if it causes dizziness or tiredness
during the day. Consult your doctor for personalized advice.

Q: How many doses of Losartan can be taken in a day?

A: Most people take one dose of Losartan daily, though the dose may vary
depending on the condition being treated. For example, the typical starting dose
for hypertension is 50 mg once a day, but it can be adjusted to 25–100 mg based
on your response. Taking more than the prescribed dose can cause excessive blood
pressure lowering, so always follow your doctor’s instructions.

Q: Can LOPITAR 50 TABLET be used during pregnancy?

A: No, Losartan is not safe to use during pregnancy. It can harm the developing
baby, especially during the second and third trimesters, potentially leading to
kidney problems or developmental issues. If you are pregnant or planning to
conceive, inform your doctor immediately to switch to a safer alternative.

Q: Can LOPITAR 50 TABLET control blood pressure effectively?

A: Yes, Losartan is highly effective in controlling high blood pressure when
taken as prescribed. However, its effectiveness depends on factors such as
adhering to the prescribed dose, maintaining a healthy diet, limiting salt
intake, and incorporating regular exercise into your routine. Regular blood
pressure monitoring is also essential.

Q: Who should not use Losartan?

A: Losartan should not be used by individuals who are pregnant or breastfeeding,
have severe kidney or liver disease, are allergic to Losartan or its
ingredients, have low blood potassium or sodium levels. Consult your doctor if
you have any underlying medical conditions or are taking other medications.

Q: What are the common side effects of Losartan?

A: The most common side effects of Losartan include dizziness, fatigue, nasal
congestion, and back pain. Some people may also experience diarrhoea or high
potassium levels (hyperkalemia). If any side effects persist or worsen, seek
medical attention.

Q: Is Losartan safe?

A: Losartan is generally considered safe when taken as prescribed by a doctor.
Regular monitoring of blood pressure, kidney function, and potassium levels is
recommended to ensure safety, especially in individuals with pre-existing kidney
or liver conditions. Always inform your doctor about any other medications or
supplements you are using.

Q: Can LOPITAR 50 TABLET be taken on an empty stomach or before food?

A: Yes, LOPITAR 50 TABLET can be taken with or without food. Food does not
significantly affect the absor
time that suits your routine. Ensure you drink plenty of water when taking the
tablet.

Q: Is LOPITAR 50 TABLET safe for kidney patients?

A: Losartan is often prescribed to protect the kidneys, especially in diabetic
patients. However, it may not be suitable for individuals with severe kidney
impairment or those on dialysis. Regular monitoring of kidney function is
essential to ensure its safe use in such cases.

Q: How long will it take for Losartan to work?

A: Losartan starts working within 1–2 hours of taking a dose, but its full blood
pressure-lowering effect may take 3–6 weeks of consistent use. If you are using
it for conditions like diabetic kidney disease, the benefits may take longer to
show, requiring regular follow-ups with your doctor.

Q: Can I stop taking Losartan once my blood pressure is controlled?

A: No, you should not stop taking Losartan without consulting your doctor. High
blood pressure is a chronic condition, and stopping the medication abruptly can
cause blood pressure to rise again, increasing the risk of complications. Your
doctor may adjust your dose or recommend lifestyle changes to complement the
treatment.

Useful Diagnostic Tests

• ECG at Home
• ECG + BP Check at Home
• Full Body Checkup with ECG & BP at Home
• Comprehensive Cardiac Risk Screening with 12 Lead ECG and BP