Ibimero S 1000/500mg Injection 1'S

Introduction About IBIMERO S 1000/500MG INJECTION

IBIMERO S 1000/500MG INJECTION is a combination of Meropenem and Sulbactam which
belong to the group of medicines called Antibiotics. It is used to manage
serious bacterial infections of the respiratory tract (Ex. pneumonia, cystic
fibrosis), urinary tract (Ex. cystitis), stomach, genital tract (Ex. postpartum
infections), skin and soft tissues (Ex. abscess, cuts, wounds), brain (Ex.
meningitis) and blood (Ex. sepsis). It can also be used to reduce fever and
chills that is suspected to be a bacterial infection in patients with a weak
immune system.

IBIMERO S 1000/500MG INJECTION should be used under careful medical supervision.
It will be given to you only by a doctor or a nurse into the vein. Make sure to
receive therapy with IBIMERO S 1000/500MG INJECTION for the stipulated duration
instructed by your doctor. Stopping therapy or skipping doses in between therapy
may not control infection effectively.

Before receiving IBIMERO S 1000/500MG INJECTION inform your doctor if you have
any liver or kidney problems. You must also inform your doctor if you previously
experienced diarrhea after taking any antibiotics as a precaution.

Inform your doctor before receiving IBIMERO S 1000/500MG INJECTION if you are
pregnant, think you may be pregnant or planning to have a baby or breastfeeding.
The most common side effects of receiving IBIMERO S 1000/500MG INJECTION are
stomach pain, nausea, vomiting, diarrhoea, headache, skin rash, pain or
inflammation at the site of injection. Consult your doctor if any of these side
effect worsens.

Uses Of IBIMERO S 1000/500MG INJECTION

It is used to manage the following serious bacterial infections:

• Respiratory tract infections (Ex. bronchitis and pneumonia)
• Urinary tract infections (Ex. cystitis, cystourethritis, pyelonephritis)
• Genital tract infections (Ex. postpartum infections)
• Stomach infections
• Brain infections (Ex. meningitis)
• Blood infections (Ex. sepsis)
• Skin and soft tissue infections (Ex. abscess, cuts, wounds)

How IBIMERO S 1000/500MG INJECTION Works

IBIMERO S 1000/500MG INJECTION contains two medicines namely meropenem and
sulbactam. Meropenem is a powerful antibiotic. It kills the susce
by interfering with the bacterial cell wall synthesis. It is effective against a
wide range of bacteria (including both gram-positive and gram-negative
bacteria).

Sulbactam is a beta-lactamase inhibitor. It sustains the anti-bacterial activity
of meropenem against the toxic bacterial proteins (such as beta lactamases).
Collectively, these actions destroy the susce
further growth and multiplication which in turn reduces the severity of the
infection.

How to use IBIMERO S 1000/500MG INJECTION

IBIMERO S 1000/500MG INJECTION will be given to you only by a doctor or a nurse
into the vein (intravenously).

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and severity of infection.

Side Effects Of IBIMERO S 1000/500MG INJECTION

Common

• stomach pain
• nausea, vomiting
• diarrhoea
• headache
• skin rash, itchy skin
• injection site reactions (pain and inflammation)

Uncommon

• increased numbers of platelets
• tingling sensation
• fungal infection of mouth or vagina (a condition called thrush)
• bowel inflammation with diarrhoea
• swelling at injection site
• fever, sore throat

Rare

• fits
• delirium

Contact your doctor immediately if you experience any of the following side
effects:

• signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
• severe skin reactions (such as widespread skin rash, blistering, peeling or bleeding on any part of the skin with fever, chills, enlarged lymph nodes and malaise or pink or reddish skin lesions on palms or soles)
• fever, skin rash, liver problems, increase in WBC count, enlarged lymph nodes
• breathlessness, red or brown urine

How To Manage Side Effects

!### Diarrhea

Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated.
Consuming ORS can also be beneficial. Do not consume any medicine on your own
without consulting your doctor. If your diarrhea worsens, contact your doctor
immediately.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

!### Injection Site Reactions

Place an ice pack at the site of injection. Do not move the affected area.
Consult your doctor if the symptom worsens.

!### Nausea And Vomiting

Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if
nausea worsens.

!### Skin rash Or Itching

Avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if your skin rash worsens.

Warning & Precautions

!### Pregnancy

ContraindicatedIBIMERO S 1000/500MG INJECTION is generally not recommended for use in pregnant
women. Therefore, consult your doctor before receiving it.

!### Breastfeeding

Monitoring requiredIBIMERO S 1000/500MG INJECTION may pass through the breast milk. Therefore, it
should be used in breastfeeding women only if considered necessary by the
physician.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected
by IBIMERO S 1000/500MG INJECTION.

!### Kidney

Use with CautionIBIMERO S 1000/500MG INJECTION should be used with caution in patients with
kidney problems. Therefore, consult your doctor before receiving it.

Liver

Use with CautionIBIMERO S 1000/500MG INJECTION should be used with caution in patients with
liver problems. Therefore, consult your doctor before receiving it.

!### Allergy

Consult your doctorTalk to doctor before receiving IBIMERO S 1000/500MG INJECTION if you are
allergic to Meropenem, Sulbactam or to any other antibiotics (such as
cephalosporins, penicillin antibiotics etc).

Others

Before receiving IBIMERO S 1000/500MG INJECTION inform your doctor if you:

• previously experienced diarrhea after taking an antibiotic
• are going to undergo blood or urine tests (Coomb’s Test)

Use in Pediatrics:

IBIMERO S 1000/500MG INJECTION is not recommended for children under the age of
3 months. Contact your doctor before receiving.

Use in Geriatrics:

There is no evidence of effects of IBIMERO S 1000/500MG INJECTION on geriatric
patients over the age of 65 years. Therefore, contact your doctor before
receiving.

Interactions

A. Drug-Drug Interactions:

Before receiving IBIMERO S 1000/500MG INJECTION, inform your doctor if you are
taking any of the following medicine:

• Probenecid (medicine used to manage gout)
• Valproic acid, sodium valproate, valpromide (medicines used to manage epilepsy)
• Oral anti-coagulants such as warfarin, acenocoumarin, phenindione, dabigatran (medicines used to manage or manage blood clots)

Overdosage:

IBIMERO S 1000/500MG INJECTION will be given to you only by a doctor or nurse in
a hospital, and so it is unlikely to receive an overdose. However, contact your
doctor if you experience any unusual side effects.

Synopsis

Drug	:	Meropenem, Sulbactam
Pharmacological Category	:	Carbapenems, Beta-lactamase Inhibitors
Therapeutic Indication	:	Serious Bacterial Infection
Dosage Forms	:	Injection

More Information

• Keep IBIMERO S 1000/500MG INJECTION out of the sight and reach of children
• Store IBIMERO S 1000/500MG INJECTION at room temperature or in a refrigerator (2-8°C) based on the instructions given in the product label

FAQs About IBIMERO S 1000/500MG INJECTION

Q: What is the use of IBIMERO S 1000/500MG INJECTION?

A: IBIMERO S 1000/500MG INJECTION is used to manage bacterial infections of the
respiratory tract, urinary tract, genital tract, skin and soft tissues, stomach,
biliary tract, blood and the brain. It can also be used to reduce fever and
chills that is suspected to be a bacterial infection in patients with a weak
immune system.

Q: How IBIMERO S 1000/500MG INJECTION works in my body?

A: IBIMERO S 1000/500MG INJECTION kills the susce
with the bacterial cell wall synthesis. It is effective against a wide range of
bacteria (including both gram-positive and gram-negative bacteria).

Q: Can IBIMERO S 1000/500MG INJECTION be used in patients with kidney
problems?

A: IBIMERO S 1000/500MG INJECTION should be used with caution in patients with
kidney problems. Therefore, consult your doctor before receiving it.

Q: How IBIMERO S 1000/500MG INJECTION is administered?

A: IBIMERO S 1000/500MG INJECTION will be given to you only by a doctor or a
nurse into the vein (intravenously).

Q: For how long should I take IBIMERO S 1000/500MG INJECTION?

A: TakeIBIMERO S 1000/500MG INJECTION for the stipulated duration as prescribed
by your doctor. Do not skip the medicine or stop receiving it on your own as it
may cause the infection to become severe.

Q: Can IBIMERO S 1000/500MG INJECTION be given to pregnant women?

A: IBIMERO S 1000/500MG INJECTION is generally not recommended for use in
pregnant women. Therefore, consult your doctor before receiving it.

Q: What precautions should I follow while receiving IBIMERO S 1000/500MG
INJECTION?

A: Before receiving IBIMERO S 1000/500MG INJECTION inform your doctor if you
have any liver or kidney problems. You must also inform your doctor if you
previously experienced diarrhea after taking any antibiotics or if you are
pregnant or breastfeeding as a precaution

Q: What arethe common side effects of receiving IBIMERO S 1000/500MG
INJECTION?

A: The most common side effects of receiving IBIMERO S 1000/500MG INJECTION are
stomach pain, nausea, vomiting, diarrhoea, headache, skin rash, pain or
inflammation at the site of injection. Consult your doctor if any of these side
effect worsens.

Q: Can I stop receiving IBIMERO S 1000/500MG INJECTION once my symptoms
subside?

A: Do not stop receiving IBIMERO S 1000/500MG INJECTION once your symptoms
subside. It is important to take the full course of IBIMERO S 1000/500MG
INJECTION to achieve better results. Failing to complete the full course of the
therapy or skipping doses in between the therapy may not result in adequate
infection control. It may also cause your symptoms to reappear.

Q: Can the use of IBIMERO S 1000/500MG INJECTION cause diarrhea?

A: IBIMERO S 1000/500MG INJECTION may cause diarrhea in some individuals. If you
experience diarrhea, drink plenty of fluids, such as water or fruit juice to
keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any
medicine on your own without consulting your doctor. If your diarrhea worsens
contact your doctor immediately.

Q: What kind of infections that IBIMERO S 1000/500MG INJECTION can manage?

A: IBIMERO S 1000/500MG INJECTION is an antibiotic. It is used to manage
infections caused by bacteria. It kills harmful bacteria by binding to the
bacterial cell and interfering with cell wall synthesis. It can manage bacterial
infections of the respiratory tract, urinary tract, genital tract, stomach,
brain, blood and skin or soft tissues.

Q: Is IBIMERO S 1000/500MG INJECTION a steroid?

A: No. IBIMERO S 1000/500MG INJECTION is an antibiotic and not a steroid
medicine.

Q: Can IBIMERO S 1000/500MG INJECTION manage viral infections?

A: No. IBIMERO S 1000/500MG INJECTION cannot manage viral infections. It manages
only bacterial infections. It acts by killing the susce
responsible for causing infections, and therefore not effective against any
viral infections.

Useful Diagnostic Tests

• Complete Blood Count (CBC)
• Renal Function Tests (RFT)
• Liver Function Tests (LFT)