ZYPENEM 1gm Injection 1's

Introduction About ZYPENEM 1GM INJECTION

ZYPENEM 1GM INJECTION contains Meropenem which belongs to the group of medicines
known as Antibiotics. It is used to manage various bacterial infections such as
pneumonia (including community acquired pneumonia and nosocomial pneumonia),
urinary tract infections, intra-abdominal infections, gynaecological infections
such as endometritis and pelvic inflammatory disease, skin and skin structure
infections, meningitis and se
management, for presumed infections in adult patients with febrile neutropenia,
used as monotherapy or in combination with anti-viral or anti-fungal agents.
ZYPENEM 1GM INJECTION is also used in the management of neutropenic patients
with fever that is suspected to be due to a bacterial infection and bacterial
infection of the blood.

During the management, your doctor may do blood tests from time to time. ZYPENEM
1GM INJECTION should be used with caution in patients with liver problems,
kidney problems, and diarrhea. ZYPENEM 1GM INJECTION is generally not
recommended in patients with gastrointestinal problems and hypersensitivity
reactions. Consult your doctor before receiving if you are pregnant or
breastfeeding women.

ZYPENEM 1GM INJECTION should be used with caution in children over 3 months old
and in geriatric patients. The common side effects of ZYPENEM 1GM INJECTION are
abdominal pain, nausea, vomiting, diarrhea, headache, skin rash, itchy skin,
pain, and inflammation. Consult your doctor if the above symptom does not
improve.

Uses Of ZYPENEM 1GM INJECTION

Used to manage bacterial infections such as:

• Pneumonia (including community acquired pneumonia and nosocomial pneumonia)
• Urinary tract infections
• Intra-abdominal infections
• Gynaecological infections such as endometritis and pelvic inflammatory disease
• Skin and skin structure infections
• Meningitis
• Se

How ZYPENEM 1GM INJECTION Works

ZYPENEM 1GM INJECTION is a broad-spectrum carbapenem antibiotic which is active
against gram-positive and gram-negative bacteria. It exerts its action by
penetrating bacterial cells readily and interfering with the synthesis of vital
cell wall components, which leads to cell death.

How to use ZYPENEM 1GM INJECTION

ZYPENEM 1GM INJECTION will be administered intravenously only by a doctor or a
nurse. Your doctor will administer the correct dose and duration for you
depending on your age, body weight, and severity of the infection.

Side Effects Of ZYPENEM 1GM INJECTION

Common

• Abdominal pain
• Nausea
• Vomiting
• Diarrhea
• Headache
• Skin rash, itchy skin
• Pain and inflammation
• Increased platelets in the blood
• Change in blood tests

Uncommon

• Tingling feeling (pins and needles)
• Infections of the mouth or the vagina are caused by a fungus (thrush)
• Diarrhea with bowel inflammation
• Sore veins
• Frequent infections, high temperature, and sore throat
• Sudden beginning of a severe rash or blistering or peeling skin (may be associated with a high fever and joint pains)

Rare

• Fits (seizures)
• Acute disorientation and confusion

Contact your doctor immediately if you experience any of the following side
effects after receiving ZYPENEM 1GM INJECTION:

• Severe allergic reaction (severe rash, itching, or hives on the skin, swelling of the face, lips, tongue, or other parts of the body, shortness of breath, wheezing, or trouble breathing)
• Serious skin reactions (serious hypersensitivity reactions involving fever, skin rash, changes in the blood tests, severe red scaly rash, skin bumps that contain pus, blisters or peeling of the skin, severe skin rashes appearing as reddish circular patches often with central blisters on the trunk, skin peeling, ulcers of mouth, throat, nose, genitals, and eyes)
• Being breathlessness when you do not expect it and red or brown urine (may be a sign of damage to red blood cells)

How To Manage Side Effects

!### Diarrhea

Drink more fluids like water or fruit juice to keep yourself hydrated. Do not
consume any medicine on your own for diarrhea without consulting your doctor.

Headache

Rest and relax. Drink more fluids like water and apply a pain-relieving balm on
the head if needed. Do not consume alcohol. If the symptom does not improve,
contact your doctor.

!### Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid
eating oil-rich or spicy foods.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have lesser and more
frequent meals. Keep a heating pad on your stomach. If the symptom does not
improve, contact your doctor.

Warning & Precautions

!### Pregnancy

Monitoring requiredZYPENEM 1GM INJECTION should not be used in pregnancy unless the benefit
justifies the potential risk to the foetus. Consult your doctor before
receiving.

!### Breastfeeding

Monitoring requiredZYPENEM 1GM INJECTION should not be used in breast-feeding women unless the
benefit justifies the potential risk to the baby. Consult your doctor before
receiving.

!### Driving and Using Machines

Use with CautionThere is no data available, but it is anticipated that ZYPENEM 1GM INJECTION
will not affect the ability to drive and use machines.

!### Kidney

Use with CautionZYPENEM 1GM INJECTION should be taken with caution in patients with kidney
problems. If needed dose will be adjusted accordingly. Consult your doctor
before receiving.

!### Liver

Use with CautionZYPENEM 1GM INJECTION should be used with caution in patients with liver
problems. Consult your doctor before receiving.

!### Allergy

ContraindicatedDo not receive ZYPENEM 1GM INJECTION if you are allergic to Meropenem,
antibiotics such as penicillins, cephalosporins, or carbapenems or to any
ingredients of this medicine.

!### Use In Pediatrics

ContraindicatedZYPENEM 1GM INJECTION is not recommended to use in children below 3 months. Your
doctor will administer the right dose depends on your child’s age, body weight
and severity of the infection for children above 3 months. Consult your doctor
for advice before receiving ZYPENEM 1GM INJECTION.

!### Use In Geriatrics

Use with CautionZYPENEM 1GM INJECTION should be used with caution in elderly patients. Consult
your physician for advice before receiving ZYPENEM 1GM INJECTION.

Others

ZYPENEM 1GM INJECTION is not recommended if you have or had:

• A history of gastro-intestinal problems like colitis
• Hypersensitivity reactions

Before receiving ZYPENEM 1GM INJECTION, inform your doctor if you have or had:

• Severe diarrhoea

Interactions

A. Drug-Drug interactions:

Before receiving ZYPENEM 1GM INJECTION inform your doctor if you are taking any
of the following medicine:

• Medicine used for the management of gout (Ex. probenecid)
• Medicines used to manage epilepsy (Ex. valproic acid, sodium valproate, valpromide)
• Medicines used to manage or manage blood clots (Ex. warfarin)

Overdosage:

ZYPENEM 1GM INJECTION will be administered to you only by a doctor or a nurse in
a hospital, and so it is unlikely to receive an overdose. However, consult your
physician or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Meropenem
Pharmacological Category	:	Carbapenem Antibiotics
Therapeutic Indication	:	Bacterial infections
Dosage Forms	:	Injection

More Information

Storage

• Keep out of reach of children
• Store below 25°C

FAQs About ZYPENEM 1GM INJECTION

Q: Can ZYPENEM 1GM INJECTION be used in children?

A: ZYPENEM 1GM INJECTION is generally not recommended to use in children below 3
months and it should be used with caution in children 3 months and older. Your
doctor will administer the right dose depends on your child’s age, body weight
and severity of the infection.

Q: Can I stop receiving ZYPENEM 1GM INJECTION if I feel my condition improved?

A: No. You should not stop receiving the management even when you feel your
condition improved. Stopping the management may bring back the infection or you
may develop resistance to ZYPENEM 1GM INJECTION.

Q: What are the common side effects of ZYPENEM 1GM INJECTION?

A: The common side effects of ZYPENEM 1GM INJECTION are abdominal pain, nausea,
vomiting, diarrhea, headache, skin rash, itchy skin, pain, and inflammation.
Consult your doctor if the above symptom does not improve.

Q: Is it safe to receive ZYPENEM 1GM INJECTION during pregnancy and lactating?

A: ZYPENEM 1GM INJECTION should not be used during pregnancy and lactating
unless the benefit justifies the potential risk to the foetus. Consult your
doctor before receiving.

Q: Can I use ZYPENEM 1GM INJECTION in patients having epilepsy?

A: Before using ZYPENEM 1GM INJECTION, consult your doctor regarding epilepsy as
the medicines used for the management of epilepsy may interfere with the effects
of ZYPENEM 1GM INJECTION.

Useful Diagnostic Tests

• Complete blood tests