COCOVA L Injection 1ml

Introduction About COCOVA L INJECTION

COCOVA L INJECTION contains Chorionic gonadotropin, which belongs to the group
of medicines called Gonadotropins. It is used to manage hypogonadism (deficiency
of sex hormones) in men. It also helps in the release of matured ovum (eggs)
from the ovaries (ovulation) among infertile women after undergoing
premanagement with suitable hormonal medicines (such as menotropins or FSH).

It also helps in sustaining pregnancy during the early stages among women who
experience habitual abortions. It can also be used in the management of
prepubertal cryptorchidism (failure of testis to descend into the scrotum)
caused by hormone deficiency in young male children (aged between 4 and 9
years).

During management with COCOVA L INJECTION, your doctor would monitor your health
condition through several blood tests and ultrasounds to avoid the risk of side
effects like fluid accumulation, abnormally enlarged ovarian follicles, or
multiple pregnancies (pregnant with more than one child), especially if you are
undergoing assisted reproductive techniques.

Before receiving COCOVA L INJECTION, inform your doctor if you have any forms of
cancer in the ovaries, uterus, breasts, or prostate. You must also inform your
doctor if you have any damage in the fallopian tubes, as management with COCOVA
L INJECTION may cause ectopic pregnancy (pregnancy outside of the womb) in such
cases.

COCOVA L INJECTION may cause a false positive pregnancy result in women who take
a pregnancy test using their blood or urine. This effect may last up to 10 days
even after discontinuing management with COCOVA L INJECTION.

COCOVA L INJECTION may be used to sustain pregnancy during the initial stages
(luteal phase). However, it should not be used in the later stages of pregnancy.
Therefore, consult your doctor for advice. It is also not recommended for use in
breastfeeding women.

The most common side effects of COCOVA L INJECTION are reaching puberty at an
early age, pain at the injection site, headaches, and irritability. Consult your
doctor if they worsen.

Uses Of COCOVA L INJECTION

• Manage prepubertal cryptorchidism (failure of testis to descend into the scrotum due to sex hormone deficiency) in male children (aged between 4 and 9 years)
• Manage male hypogonadism (failure of testis to produce male sex hormones)
• Induces ovulation among infertile women
• Supports pregnancy among women who experience habitual abortions

How COCOVA L INJECTION Works

COCOVA L INJECTION is a gonadotrophic hormone that stimulates the production of
sex hormones in both men and women. In men, it acts by stimulating the release
of androgens, which are responsible for the development of secondary sexual
characteristics and for regulating the onset of puberty. It also helps to move
down the testicles into the scrotum in children having undescended testis.

In women, it triggers the release of mature eggs from the ovaries and helps to
sustain pregnancy by supplementing enough female sex hormones (estrogen and
progesterone), which are required for maintaining a successful conce

How to use COCOVA L INJECTION

COCOVA L INJECTION will be given to you only by a doctor or a nurse into the
muscle (intramuscularly) or under the skin (subcutaneously). Your doctor will
decide the correct dose and duration of therapy for you depending upon your age,
body weight, and health condition.

Side Effects Of COCOVA L INJECTION

Common

• headache
• irritability, restlessness, depression
• tiredness
• fluid accumulation (edema)
• precocious puberty (reaching puberty at an early age)
• breast enlargement in men
• pain at the injection site

Rare

Consult your doctor immediately if you experience any of the following side
effects after receiving COCOVA L INJECTION:

• signs of ovarian hyperstimulation syndrome (such as lower stomach pain, breast pain, swollen stomach, rapid weight gain, nausea, vomiting, difficulty breathing, clearly enlarged ovaries in ultrasound, fluid accumulation in the lungs, and decreased urine production)
• rupture of ovarian cysts leading to internal bleeding
• multiple pregnancy
• signs of allergic reactions (such as skin rash, redness, itching, rapid or uneven pulse, swelling of the tongue and throat, sneezing, wheezing, or serious difficulty in breathing)
• serious blood clotting problems which may cause chest pain, breathlessness, stroke, or heart attack
• signs of sexual precocity (development of sexual characters) in very young children

Warning & Precautions

!### Pregnancy

Consult your doctorCOCOVA L INJECTION may be used to sustain pregnancy during the initial stages
(luteal phase). However, it should not be used in the later stages of pregnancy.
Therefore, consult your doctor for advice.

!### Breastfeeding

ContraindicatedCOCOVA L INJECTION is not recommended for use in breastfeeding women. Therefore,
consult your doctor before receiving it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected
by COCOVA L INJECTION.

!### Alcohol

ContraindicatedAvoid consum

!### Kidney

Use with CautionCOCOVA L INJECTION should be used with caution in patients having or ever had
any kidney diseases. Therefore, consult your doctor before receiving it.

!### Allergy

ContraindicatedDo not receive COCOVA L INJECTION if you are allergic to chorionic gonadotropin.

!### Lungs

Use with CautionCOCOVA L INJECTION should be used with caution in patients having or ever had
asthma. Therefore, consult your doctor before receiving it.

!### Heart Disease

Use with CautionCOCOVA L INJECTION should be used with caution in patients having or ever had
heart diseases (such as high blood pressure). Therefore, consult your doctor
before receiving it.

!### Use In Pediatrics

Consult your doctorCOCOVA L INJECTION can be used in children aged between 4 and 9 years. It is not
recommended for use in children aged under 4 years due to a lack of safety data.
However, consult your doctor for advice.

Others

COCOVA L INJECTION is not recommended for use if you:

• have tumors in the pituitary gland (Ex. pituitary adenoma) or uterus (fibroids)
• have ovarian cancer, uterine cancer, breast cancer, or prostate cancer
• have androgen-dependent neoplasms (any forms of tumors caused by excessive androgen production)
• have any type of uncontrolled hormonal disorders (Ex. dysfunction of thyroid gland, pituitary gland, or adrenal glands)
• have failure of ovaries (due to menopause)
• have failure of testis
• are undergoing any surgical procedures in the female reproductive tract (such as tubal occlusion)
• have signs of reaching puberty at a very early age
• have any blood clot problems (like deep vein thrombosis)
• have malformations of sexual organs
• have prepubertal cryptorchidism caused by anatomical obstruction
• have abnormal vaginal bleeding

Before receiving COCOVA L INJECTION, inform your physician if you:

• have or ever had migraine (severe throbbing pain usually on one side of the head)
• have or ever had epilepsy (fits or seizures)
• have damaged fallopian tubes
• are going to have a blood/urine test to detect pregnancy or ovulation

Interactions

A. Drug-Drug interactions:

Before receiving COCOVA L INJECTION, inform your doctor if you are taking:

• other medicines used to manage stimulated ovulation (Ex. menotropin, clomiphene citrate)

Overdosage:

COCOVA L INJECTION will be given to you only by a doctor or nurse, and so it is
unlikely to receive an overdose. However, if you experience any unusual symptoms
like lower stomach pain, swollen stomach, rapid weight gain, nausea, vomiting,
breast pain, difficulty breathing, fluid accumulation in the chest, or
difficulty passing urine, consult your doctor immediately, as it could be signs
of ovarian hyperstimulation syndrome.

Synopsis

Drug	:	Chorionic Gonadotropin
Pharmacological Category	:	Synthetic Hormones
Therapeutic Indication	:	Male Hypogonadism, Female Infertility, Prepubertal cryptorchidism
Dosage Forms	:	Injection

More Information

Storage

• Keep COCOVA L INJECTION out of reach of children
• Store COCOVA L INJECTION in a refrigerator (at 2-8°C)

FAQs About COCOVA L INJECTION

Q: Can COCOVA L INJECTION help me lose weight?

A: COCOVA L INJECTION has no effect on fat metabolism, fat distribution, or
appetite. There is no substantial evidence to prove that COCOVA L INJECTION can
reduce body weight or has its effects on the therapy of obesity. Consult your
doctor before receiving COCOVA L INJECTION if you are wishing to use it for
losing weight.

Q: Can COCOVA L INJECTION be used in men?

A: Yes. COCOVA L INJECTION can be used to manage hypogonadism and its related
complications in men. It helps in the development of secondary sexual
characteristics in males who experience delayed onset of puberty and moves down
testis into the scrotum among patients having undescended testis. It can also be
used in male children aged between 4 and 9 years. Your doctor will prescribe a
suitable dose for you depending upon your condition.

Q: Can COCOVA L INJECTION help in getting pregnant?

A: Yes. COCOVA L INJECTION stimulates the release of eggs from the ovaries among
infertile women. It also helps to sustain pregnancy among women experiencing
habitual abortions by supplementing enough female sex hormones (estrogen and
progesterone), which are required for maintaining a successful conce
However, consult your doctor before receiving it.

Q: Can COCOVA L INJECTION cause children to puberty at an early age?

A: Yes. COCOVA L INJECTION can cause prepubertal precocity (reaching puberty in
early age) and sexual precocity (development of sexual characters) in very young
children due to increased production of sex hormones. Proper dose adjustments
and careful monitoring during management with COCOVA L INJECTION can overcome
this. However, if your child shows any such changes, consult your doctor
immediately. Your doctor might reduce the dose or suggest an alternative
therapy.

Q: Can pregnant women use COCOVA L INJECTION?

A: Although, COCOVA L INJECTION helps to sustain pregnancy at the early stages
(preferably from luteal phase to first 2 months), it is not recommended for use
during the later stages. However, consult your doctor for advice.

Q: Can COCOVA L INJECTION be used to improve sexual performance?

A: No. COCOVA L INJECTION generally does not improve sexual performance. It only
stimulates the release of sex hormones in men and women, which ultimately
resolves infertility issues and supports better health.

Q: Can COCOVA L INJECTION be self-administered?

A: No. COCOVA L INJECTION is generally administered by a doctor or nurse into
the muscle (intramuscularly) or under the skin (subcutaneously). Do not
self-administer COCOVA L INJECTION without consulting your doctor. In the case
of subcutaneous administration, your doctor may teach you how, when, and where
GBNKEYWORD] should be administered. Kindly follow the instructions advised by
the doctor if requested for self-administration. Consult your doctor if you have
any doubts regarding the administration of COCOVA L INJECTION.

Q: Can COCOVA L INJECTION be used to manage PCOD?

A: Before receiving COCOVA L INJECTION, inform your doctor if you have
polycystic ovarian disease (PCOD). Your doctor will decide whether you can use
COCOVA L INJECTION or not based on your disease condition.

Q: Can management with COCOVA L INJECTION cause twin pregnancy?

A: Yes. Usage of COCOVA L INJECTION has a higher risk of being pregnant with
more than one child at the same time (twin pregnancy or multiple pregnancy) than
if conceived naturally. This risk further increases if management with COCOVA L
INJECTION is combined with assisted reproductive techniques. To avoid this, your
doctor will carefully monitor you through several blood tests (for estradiol
levels) and ultrasounds.

Q: Will the use of COCOVA L INJECTION cause breast pain or tenderness?

A: COCOVA L INJECTION may cause breast pain or tenderness in some individuals.
It is caused by overstimulation of the ovaries. If the symptom worsens, consult
your doctor immediately.

Q: Why am I experiencing positive results in the pregnancy kit after taking
COCOVA L INJECTION even though I’m not pregnant?

A: It is because COCOVA L INJECTION contains a medicine that is similar to the
endogenous HCG secreted by the placenta of pregnant women. Because pregnancy
kits are designed in such a way to capture the levels of naturally produced HCG
hormone from the urine of pregnant women, they tend to show a false positive
result after receiving COCOVA L INJECTION, even if you are not pregnant.

Q: What precautions need to be followed while taking COCOVA L INJECTION?

A: Before receiving COCOVA L INJECTION, inform your doctor if you have any other
problems in reproductive organs like a tumor or cancer, unexplained vaginal
bleeding, PCOD, or damage in fallopian tubes. Regularly monitor your health
condition through blood tests and ultrasounds as instructed by your doctor.
Regularly receive COCOVA L INJECTION as instructed by your physician. If you
become pregnant while undergoing management with COCOVA L INJECTION, inform your
doctor immediately.

Q: Can COCOVA L INJECTION be used to induce periods?

A: COCOVA L INJECTION is a hormone that is primarily used to improve the chances
of getting pregnant in infertile women. Only failure in fertilization or
overstimulation of ovaries during therapy can cause miscarriage or menstruation.
COCOVA L INJECTION is not a first-line medicine to induce periods among patients
who have amenorrhea (lack of periods). Consult your doctor for some alternative
therapy.

Useful Diagnostic Tests

• Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance – ELISA
• Follicle Stimulating Hormone (Fsh)
• Complete Blood Count (CBC)/ Hemogram
• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Thyroid Stimulating Hormone
• Testosterone
• Testosterone Free