Profasi 5000IU Injection 1ml

Introduction About PROFASI 5000IU INJECTION

PROFASI 5000IU INJECTION contains Chorionic gonadotropin, which belongs to the
group of medicines called Gonadotropins. It is used to manage hypogonadism
(deficiency of sex hormones) in men. It also helps in the release of matured
ovum (eggs) from the ovaries (ovulation) among infertile women after undergoing
premanagement with suitable hormonal medicines (such as menotropins or FSH).

It also helps in sustaining pregnancy during the early stages among women who
experience habitual abortions. It can also be used in the management of
prepubertal cryptorchidism (failure of testis to descend into the scrotum)
caused by hormone deficiency in young male children (aged between 4 and 9
years).

During management with PROFASI 5000IU INJECTION, your doctor would monitor your
health condition through several blood tests and ultrasounds to avoid the risk
of side effects like fluid accumulation, abnormally enlarged ovarian follicles,
or multiple pregnancies (pregnant with more than one child), especially if you
are undergoing assisted reproductive techniques.

Before receiving PROFASI 5000IU INJECTION, inform your doctor if you have any
forms of cancer in the ovaries, uterus, breasts, or prostate. You must also
inform your doctor if you have any damage in the fallopian tubes, as management
with PROFASI 5000IU INJECTION may cause ectopic pregnancy (pregnancy outside of
the womb) in such cases.

PROFASI 5000IU INJECTION may cause a false positive pregnancy result in women
who take a pregnancy test using their blood or urine. This effect may last up to
10 days even after discontinuing management with PROFASI 5000IU INJECTION.

PROFASI 5000IU INJECTION may be used to sustain pregnancy during the initial
stages (luteal phase). However, it should not be used in the later stages of
pregnancy. Therefore, consult your doctor for advice. It is also not recommended
for use in breastfeeding women.

The most common side effects of PROFASI 5000IU INJECTION are reaching puberty at
an early age, pain at the injection site, headaches, and irritability. Consult
your doctor if they worsen.

Uses Of PROFASI 5000IU INJECTION

• Manage prepubertal cryptorchidism (failure of testis to descend into the scrotum due to sex hormone deficiency) in male children (aged between 4 and 9 years)
• Manage male hypogonadism (failure of testis to produce male sex hormones)
• Induces ovulation among infertile women
• Supports pregnancy among women who experience habitual abortions

How PROFASI 5000IU INJECTION Works

PROFASI 5000IU INJECTION is a gonadotrophic hormone that stimulates the
production of sex hormones in both men and women. In men, it acts by stimulating
the release of androgens, which are responsible for the development of secondary
sexual characteristics and for regulating the onset of puberty. It also helps to
move down the testicles into the scrotum in children having undescended testis.

In women, it triggers the release of mature eggs from the ovaries and helps to
sustain pregnancy by supplementing enough female sex hormones (estrogen and
progesterone), which are required for maintaining a successful conce

How to use PROFASI 5000IU INJECTION

PROFASI 5000IU INJECTION will be given to you only by a doctor or a nurse into
the muscle (intramuscularly) or under the skin (subcutaneously). Your doctor
will decide the correct dose and duration of therapy for you depending upon your
age, body weight, and health condition.

Side Effects Of PROFASI 5000IU INJECTION

Common

• headache
• irritability, restlessness, depression
• tiredness
• fluid accumulation (edema)
• precocious puberty (reaching puberty at an early age)
• breast enlargement in men
• pain at the injection site

Rare

Consult your doctor immediately if you experience any of the following side
effects after receiving PROFASI 5000IU INJECTION:

• signs of ovarian hyperstimulation syndrome (such as lower stomach pain, breast pain, swollen stomach, rapid weight gain, nausea, vomiting, difficulty breathing, clearly enlarged ovaries in ultrasound, fluid accumulation in the lungs, and decreased urine production)
• rupture of ovarian cysts leading to internal bleeding
• multiple pregnancy
• signs of allergic reactions (such as skin rash, redness, itching, rapid or uneven pulse, swelling of the tongue and throat, sneezing, wheezing, or serious difficulty in breathing)
• serious blood clotting problems which may cause chest pain, breathlessness, stroke, or heart attack
• signs of sexual precocity (development of sexual characters) in very young children

Warning & Precautions

!### Pregnancy

Consult your doctorPROFASI 5000IU INJECTION may be used to sustain pregnancy during the initial
stages (luteal phase). However, it should not be used in the later stages of
pregnancy. Therefore, consult your doctor for advice.

!### Breastfeeding

ContraindicatedPROFASI 5000IU INJECTION is not recommended for use in breastfeeding women.
Therefore, consult your doctor before receiving it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected
by PROFASI 5000IU INJECTION.

!### Alcohol

ContraindicatedAvoid consum

!### Kidney

Use with CautionPROFASI 5000IU INJECTION should be used with caution in patients having or ever
had any kidney diseases. Therefore, consult your doctor before receiving it.

!### Allergy

ContraindicatedDo not receive PROFASI 5000IU INJECTION if you are allergic to chorionic
gonadotropin.

!### Lungs

Use with CautionPROFASI 5000IU INJECTION should be used with caution in patients having or ever
had asthma. Therefore, consult your doctor before receiving it.

!### Heart Disease

Use with CautionPROFASI 5000IU INJECTION should be used with caution in patients having or ever
had heart diseases (such as high blood pressure). Therefore, consult your doctor
before receiving it.

!### Use In Pediatrics

Consult your doctorPROFASI 5000IU INJECTION can be used in children aged between 4 and 9 years. It
is not recommended for use in children aged under 4 years due to a lack of
safety data. However, consult your doctor for advice.

Others

PROFASI 5000IU INJECTION is not recommended for use if you:

• have tumors in the pituitary gland (Ex. pituitary adenoma) or uterus (fibroids)
• have ovarian cancer, uterine cancer, breast cancer, or prostate cancer
• have androgen-dependent neoplasms (any forms of tumors caused by excessive androgen production)
• have any type of uncontrolled hormonal disorders (Ex. dysfunction of thyroid gland, pituitary gland, or adrenal glands)
• have failure of ovaries (due to menopause)
• have failure of testis
• are undergoing any surgical procedures in the female reproductive tract (such as tubal occlusion)
• have signs of reaching puberty at a very early age
• have any blood clot problems (like deep vein thrombosis)
• have malformations of sexual organs
• have prepubertal cryptorchidism caused by anatomical obstruction
• have abnormal vaginal bleeding

Before receiving PROFASI 5000IU INJECTION, inform your physician if you:

• have or ever had migraine (severe throbbing pain usually on one side of the head)
• have or ever had epilepsy (fits or seizures)
• have damaged fallopian tubes
• are going to have a blood/urine test to detect pregnancy or ovulation

Interactions

A. Drug-Drug interactions:

Before receiving PROFASI 5000IU INJECTION, inform your doctor if you are taking:

• other medicines used to manage stimulated ovulation (Ex. menotropin, clomiphene citrate)

Overdosage:

PROFASI 5000IU INJECTION will be given to you only by a doctor or nurse, and so
it is unlikely to receive an overdose. However, if you experience any unusual
symptoms like lower stomach pain, swollen stomach, rapid weight gain, nausea,
vomiting, breast pain, difficulty breathing, fluid accumulation in the chest, or
difficulty passing urine, consult your doctor immediately, as it could be signs
of ovarian hyperstimulation syndrome.

Synopsis

Drug	:	Chorionic Gonadotropin
Pharmacological Category	:	Synthetic Hormones
Therapeutic Indication	:	Male Hypogonadism, Female Infertility, Prepubertal cryptorchidism
Dosage Forms	:	Injection

More Information

Storage

• Keep PROFASI 5000IU INJECTION out of reach of children
• Store PROFASI 5000IU INJECTION in a refrigerator (at 2-8°C)

FAQs About PROFASI 5000IU INJECTION

Q: Can PROFASI 5000IU INJECTION help me lose weight?

A: PROFASI 5000IU INJECTION has no effect on fat metabolism, fat distribution,
or appetite. There is no substantial evidence to prove that PROFASI 5000IU
INJECTION can reduce body weight or has its effects on the therapy of obesity.
Consult your doctor before receiving PROFASI 5000IU INJECTION if you are wishing
to use it for losing weight.

Q: Can PROFASI 5000IU INJECTION be used in men?

A: Yes. PROFASI 5000IU INJECTION can be used to manage hypogonadism and its
related complications in men. It helps in the development of secondary sexual
characteristics in males who experience delayed onset of puberty and moves down
testis into the scrotum among patients having undescended testis. It can also be
used in male children aged between 4 and 9 years. Your doctor will prescribe a
suitable dose for you depending upon your condition.

Q: Can PROFASI 5000IU INJECTION help in getting pregnant?

A: Yes. PROFASI 5000IU INJECTION stimulates the release of eggs from the ovaries
among infertile women. It also helps to sustain pregnancy among women
experiencing habitual abortions by supplementing enough female sex hormones
(estrogen and progesterone), which are required for maintaining a successful
conce

Q: Can PROFASI 5000IU INJECTION cause children to puberty at an early age?

A: Yes. PROFASI 5000IU INJECTION can cause prepubertal precocity (reaching
puberty in early age) and sexual precocity (development of sexual characters) in
very young children due to increased production of sex hormones. Proper dose
adjustments and careful monitoring during management with PROFASI 5000IU
INJECTION can overcome this. However, if your child shows any such changes,
consult your doctor immediately. Your doctor might reduce the dose or suggest an
alternative therapy.

Q: Can pregnant women use PROFASI 5000IU INJECTION?

A: Although, PROFASI 5000IU INJECTION helps to sustain pregnancy at the early
stages (preferably from luteal phase to first 2 months), it is not recommended
for use during the later stages. However, consult your doctor for advice.

Q: Can PROFASI 5000IU INJECTION be used to improve sexual performance?

A: No. PROFASI 5000IU INJECTION generally does not improve sexual performance.
It only stimulates the release of sex hormones in men and women, which
ultimately resolves infertility issues and supports better health.

Q: Can PROFASI 5000IU INJECTION be self-administered?

A: No. PROFASI 5000IU INJECTION is generally administered by a doctor or nurse
into the muscle (intramuscularly) or under the skin (subcutaneously). Do not
self-administer PROFASI 5000IU INJECTION without consulting your doctor. In the
case of subcutaneous administration, your doctor may teach you how, when, and
where GBNKEYWORD] should be administered. Kindly follow the instructions advised
by the doctor if requested for self-administration. Consult your doctor if you
have any doubts regarding the administration of PROFASI 5000IU INJECTION.

Q: Can PROFASI 5000IU INJECTION be used to manage PCOD?

A: Before receiving PROFASI 5000IU INJECTION, inform your doctor if you have
polycystic ovarian disease (PCOD). Your doctor will decide whether you can use
PROFASI 5000IU INJECTION or not based on your disease condition.

Q: Can management with PROFASI 5000IU INJECTION cause twin pregnancy?

A: Yes. Usage of PROFASI 5000IU INJECTION has a higher risk of being pregnant
with more than one child at the same time (twin pregnancy or multiple pregnancy)
than if conceived naturally. This risk further increases if management with
PROFASI 5000IU INJECTION is combined with assisted reproductive techniques. To
avoid this, your doctor will carefully monitor you through several blood tests
(for estradiol levels) and ultrasounds.

Q: Will the use of PROFASI 5000IU INJECTION cause breast pain or tenderness?

A: PROFASI 5000IU INJECTION may cause breast pain or tenderness in some
individuals. It is caused by overstimulation of the ovaries. If the symptom
worsens, consult your doctor immediately.

Q: Why am I experiencing positive results in the pregnancy kit after taking
PROFASI 5000IU INJECTION even though I’m not pregnant?

A: It is because PROFASI 5000IU INJECTION contains a medicine that is similar to
the endogenous HCG secreted by the placenta of pregnant women. Because pregnancy
kits are designed in such a way to capture the levels of naturally produced HCG
hormone from the urine of pregnant women, they tend to show a false positive
result after receiving PROFASI 5000IU INJECTION, even if you are not pregnant.

Q: What precautions need to be followed while taking PROFASI 5000IU
INJECTION?

A: Before receiving PROFASI 5000IU INJECTION, inform your doctor if you have any
other problems in reproductive organs like a tumor or cancer, unexplained
vaginal bleeding, PCOD, or damage in fallopian tubes. Regularly monitor your
health condition through blood tests and ultrasounds as instructed by your
doctor. Regularly receive PROFASI 5000IU INJECTION as instructed by your
physician. If you become pregnant while undergoing management with PROFASI
5000IU INJECTION, inform your doctor immediately.

Q: Can PROFASI 5000IU INJECTION be used to induce periods?

A: PROFASI 5000IU INJECTION is a hormone that is primarily used to improve the
chances of getting pregnant in infertile women. Only failure in fertilization or
overstimulation of ovaries during therapy can cause miscarriage or menstruation.
PROFASI 5000IU INJECTION is not a first-line medicine to induce periods among
patients who have amenorrhea (lack of periods). Consult your doctor for some
alternative therapy.

Useful Diagnostic Tests

• Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance – ELISA
• Follicle Stimulating Hormone (Fsh)
• Complete Blood Count (CBC)/ Hemogram
• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Thyroid Stimulating Hormone
• Testosterone
• Testosterone Free