BENITOWA BETA 25mg Tablet 15's

Introduction About BENITOWA BETA 25MG TABLET

BENITOWA BETA 25MG TABLET is a combination of Benidipine and Metoprolol which
belongs to the group of medicines calledAntihypertensives. It is used in the
management of hypertension, a condition in which the force of the blood against
the artery walls is too high for a long-term resulting in blurry or double
vision, light-headedness, fainting, fatigue, headache, palpitations, nosebleeds,
shortness of breath and nausea or vomiting. It may eventually cause health
problems such as heart disease.

Avoid drinking grapefruit juice while taking BENITOWA BETA 25MG TABLET as it may
reduce your blood pressure. BENITOWA BETA 25MG TABLET is not recommended in
patients having severe asthma or severe attack of wheezing and non-cancerous
tumour (phaeochromocytoma) near kidneys, serious heart or blood vessel diseases
and decreased blood pressure.

BENITOWA BETA 25MG TABLET should be used with caution among patients having
liver dysfunction or liver disease. This medicine is also not recommended for
use among pregnant, breast-feeding women, children and adolescents (under 18
years of age). It should be cautiously used among elderly people. Consult your
doctor before taking it.

The most common side effects of taking BENITOWA BETA 25MG TABLET are headache,
dizziness, nausea, vomiting, diarrhoea and stomach pain. Consult your doctor if
any of the side effects worsen.

Uses Of BENITOWA BETA 25MG TABLET

• Manage high blood pressure

How BENITOWA BETA 25MG TABLET Works

BENITOWA BETA 25MG TABLET helps to reduce high blood pressure, where benidipine
works by relaxing the blood vessels supplying the heart to improve the blood
flow by reducing the influx of calcium into cells and metoprolol works by
reducing the force of contraction of the heart muscles by blocking the effects
of certain hormones called adrenaline and making the heart to beat more easily
thus it lowers the blood pressure. These actions together effectively reduce the
high blood pressure.

How to use BENITOWA BETA 25MG TABLET

Take BENITOWA BETA 25MG TABLET as advised by your physician. Swallow the
medicine with a glass of water. Do not crush or chew the medicine. Your doctor
will decide the correct dose and duration for you depending upon your age, body
weight and disease condition. Do not stop taking BENITOWA BETA 25MG TABLET
unless your doctor advice you to stop.

Side Effects Of BENITOWA BETA 25MG TABLET

Common

• palpitation
• dizziness, headache
• skin rash, itching
• sensitivity to sunlight
• enlargement of breasts in men
• unusual weakness
• slow heartbeat
• low blood pressure which may make you faint and dizzy
• shortness of breath especially while exercising
• nausea and vomiting
• stomach pain

Uncommon

• disturbed or lack of sleep
• feeling less alert
• coldness
• depressed mood
• tingling or numb feeling in hands or feet
• muscle cramps
• irregular heartbeat
• fluid retention
• breathlessness, wheeziness
• diarrhoea, constipation

Rare

Stop taking BENITOWA BETA 25MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• signs of liver problems (generalized tiredness, weakness, yellowish discolouration of skin and eyes and loss of appetite)

How To Manage Side Effects

Nausea or vomiting:

Take this medicine with or soon after meals. Stick to simple meals. Avoid eating
oily or spicy foods. If the symptom does not improve, contact your doctor.

Constipation:

Eat plenty of fibre-containing foods such as fresh fruits, vegetables, cereals
and drink lots of water. Exercise more regularly. If the symptom does not
improve, contact your doctor.

Diarrhoea:

Drink lot of fluids such as normal water or fruit juice to keep yourself
hydrated. Do not take any medicine on your own to manage diarrhoea without
seeking the opinion of your doctor.

Stomach pain:

Try to rest and relax. Eat slowly and try to have smaller and more frequent
meals. Keep a heating pad on your stomach. If the symptom does not improve,
contact your doctor.

Headache

Use a cold pack or hot pads to reduce the pressure on your head. Reduce looking
into bright light and try to get adequate sleep. Consult your doctor if the
symptom gets worse.

Skin rash:

Avoid bathing in hot water because hot water can irritate your skin further. Do
not scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if the symptom worsens.

Warning & Precautions

!### Pregnancy

BENITOWA BETA 25MG TABLET is not recommended for use in pregnant women or women
planning to get pregnant. Therefore, consult your doctor before taking BENITOWA
BETA 25MG TABLET.

!### Breastfeeding

BENITOWA BETA 25MG TABLET is not recommended for use in breastfeeding women.
Consult your doctor before taking BENITOWA BETA 25MG TABLET.

!### Driving and Using Machines

Do not drive or operate any machines if you feel dizzy or light-headedness,
sleepy or if you have any problems with your eyes while taking BENITOWA BETA
25MG TABLET.

!### Alcohol

Avoid consum
aggravate your existing condition.

!### Kidney

BENITOWA BETA 25MG TABLET is not recommended for use in patients having
non-cancerous tumour (phaeochromocytoma) near kidneys. Consult your doctor
before taking BENITOWA BETA 25MG TABLET.

!### Liver

GBNKEYWORD] should be taken with caution in patients with severe liver disease
or impaired liver function. Consult your doctor before taking BENITOWA BETA 25MG
TABLET.

!### Allergy

Do not take BENITOWA BETA 25MG TABLET if you are allergic to benidipine,
metoprolol or any other beta-blockers such as acebutolol and atenolol.

!### Lungs

BENITOWA BETA 25MG TABLET is not recommended for use in patients having severe
asthma or severe attack of wheezing. It should be used with caution among
patients having asthma, bronchitis (inflammation of bronchi) or any lung
disorders. Consult your doctor before taking BENITOWA BETA 25MG TABLET.

!### Heart Disease

BENITOWA BETA 25MG TABLET is not recommended for use in patients having serious
heart or blood vessel disorders and decreased blood pressure. BENITOWA BETA 25MG
TABLET should be used with caution in patients having heart diseases such as
cardiogenic shock (heart cannot pump blood suddenly), slow heart rate or any
problems with the circulation and if you are suffering from a rare form of
angina (chest pain) called prinzmetal's angina. Consult your doctor before
taking BENITOWA BETA 25MG TABLET.

Others

BENITOWA BETA 25MG TABLET is not recommended for use if you have:

• metabolic acidosis (condition in which your blood become acidic than normal)

Before taking BENITOWA BETA 25MG TABLET, inform your doctor if you:

• require any operations which needs anaesthesia
• have psoriasis (skin disease)
• have diabetes (increased blood sugar levels)
• had severe allergic reactions

Use in paediatrics:

BENITOWA BETA 25MG TABLET is not recommended for use in children and adolescents
(under 18 years of age). Consult your child’s doctor for advice.

Use in geriatrics:

BENITOWA BETA 25MG TABLET should be used with caution in elderly patients.
Consult your doctor before taking BENITOWA BETA 25MG TABLET.

Interactions

A. Drug - Drug interactions:

Before taking BENITOWA BETA 25MG TABLET, inform your doctor if you are taking
any of the following medicines:

• medicines used to reduce blood pressure (Ex atenolol, betaxolol, prazosin and calcium channel blockers such as verapamil or diltiazem)

• medicines used to manage heart diseases (Ex. digoxin, nitrates such as nitroglycerin, and anti-arrhythmic medicines such as amiodarone, flecainide)

• cimetidine (medicine used to manage stomach acidity and ulcers)

• ergotamine (medicine used to manage migraine)

• medicines used to manage depression and other mental illness (Ex. citalopram, paroxetine and lorazepam)

• medicines used to manage HIV infection (Ex. indinavir, ritonavir)

• medicines used to manage allergic conditions such as common cold or other allergies (Ex.  cetirizine, fexofenadine)

• medicine used to manage malaria (Ex. mefloquine)

• medicines used to manage fungal infections (Ex. fluconazole, itraconazole)

• rifampicin (medicine used to manage tuberculosis)

• medicines used to manage diabetes (Ex. glimepiride, insulin)

• medicines used to manage pain and inflammation (Ex. ibuprofen, diclofenac)

• lidocaine (medicine used as a local anaesthetic agent)

B. Drug - Food interaction:

Avoid drinking grapefruit juice while taking BENITOWA BETA 25MG TABLET as it may
cause severe decrease in blood pressure.

Overdosage:

If you or anyone else accidentally take too much of BENITOWA BETA 25MG TABLET,
consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Benidipine and Metoprolol
Pharmacological Category	:	Calcium channel blockers, Beta blockers
Therapeutic Indication	:	High blood pressure
Dosage Forms	:	Tablet

More Information

• Keep BENITOWA BETA 25MG TABLET out of reach of children
• Store at room temperature

FAQs About BENITOWA BETA 25MG TABLET

How does BENITOWA BETA 25MG TABLET work?

BENITOWA BETA 25MG TABLET helps to control high blood pressure, where benidipine
works by relaxing the blood vessels supplying the heart to improve the blood
flow by reducing the influx of calcium ion into cells and metoprolol works by
reducing the force of contraction of the heart muscles by blocking the effects
of certain hormones called adrenaline and making the heart to beat more easily
thus it lowers the blood pressure. These actions together effectively reduce the
high blood pressure.

What to do If I forget to take BENITOWA BETA 25MG TABLET?

You should take BENITOWA BETA 25MG TABLET immediately when you remember. If it
is time for your next dose skip the missed dose and follow your regular dose
schedule. Do not double the dose to match up your missed dose.

For how long should I take BENITOWA BETA 25MG TABLET?

You should continue taking BENITOWA BETA 25MG TABLET unless your doctor tells
you to stop the medicine. Blood pressure medicines will be usually taken for
lifetime to manage complications due to high blood pressure. Your doctor may
change management with other hypertension drug, if you do not attain effective
therapeutic outcome with BENITOWA BETA 25MG TABLET.

What are the common side effects of BENITOWA BETA 25MG TABLET?

The most common side effects of taking BENITOWA BETA 25MG TABLET are palpitation
(rapid heartbeat), dizziness, headache, skin rash, itching, sensitivity to
sunlight, gynecomastia (enlargement of breast in men), unusual weakness, slow
heartbeat, low blood pressure which may make you faint and dizzy, shortness of
breath especially while exercising, nausea, vomiting and stomach pain. Consult
your doctor immediately if any of the side effects bothers you.

Does BENITOWA BETA 25MG TABLET impair my ability to drive?

Do not drive or operate any machines if you experience dizziness,
light-headedness, sleepiness or any problems related to eyes as it may impair
your ability to drive or work. You may ask someone to drive for you or follow
appropriate precautions before driving after consulting with your doctor.

Useful Diagnostic Tests

• Kidney function test
• Liver function test