Zurig 40mg Tablet 7'S

Introduction About ZURIG 40MG TABLET

ZURIG 40MG TABLET is used in the management of gout which is associated with an
excess of a chemical called uric acid in the body. It contains a medicine called
Febuxostat which is used to lower uric acid levels in patients with gout. It
works by blocking the actions of an enzyme called xanthine oxidase, which plays
a key role in the production of uric acid in the body.

Take ZURIG 40MG TABLET as advised by your physician. It can be taken with or
without food. During the initial days of the therapy, febuxostat can cause flare
up of gout attacks in some individuals which is normal. Over the period of use,
these flare ups usually reduce and becomes less painful upon everyday usage. If
these flare ups are not manageable, consult your doctor for advice.

Do not take ZURIG 40MG TABLET if you are allergic to febuxostat, allopurinol and
have an active gout attack. ZURIG 40MG TABLET should be used only when the gout
attack subsides completely.

Before taking ZURIG 40MG TABLET, inform your doctor if you have any pre-existing
liver, kidney or heart diseases or thyroid problems. The most common side
effects of taking ZURIG 40MG TABLET are nausea, diarrhea, headache, dizziness,
sleepiness, flare ups if gout attack, edema and abnormal liver test results.
Consult your doctor if they trouble you.

Uses Of ZURIG 40MG TABLET

• Management of gout and hyperuricemia (increased uric acid levels in the body) in adults

How ZURIG 40MG TABLET Works

ZURIG 40MG TABLET works by selectively inhibiting an enzyme called xanthine
oxidase, which plays a key role in the production of uric acid in the body. By
blocking this enzyme, febuxostat reduces the formation of uric acid, thereby
lowering its levels in the blood. This helps reducing the formation of uric acid
crystals, which can cause painful gout attacks and joint damage.

How to use ZURIG 40MG TABLET

Take ZURIG 40MG TABLET as advised by your physician. It can be taken with or
without food. Swallow the medicine with a glass of water. Do not crush or chew
the medicine.

Your doctor will decide the correct dose and duration of therapy for you based
on your age, body weight and health condition. Do not stop taking ZURIG 40MG
TABLET without consulting your doctor.

During the initial days of the therapy, febuxostat can cause flare up of gout
attacks in some individuals which is normal. Over the period of use, these flare
ups usually reduce and becomes less painful upon everyday usage. If these flare
ups are not manageable, consult your doctor for advice.

Side Effects Of ZURIG 40MG TABLET

Common

• Diarrhea
• Headache
• Skin rashes
• Abnormal liver test results
• Nausea
• Increase in gout symptoms
• Edema (localised swelling)

Uncommon

• decreased appetite
• change in blood sugar levels (diabetes)
• loss of sex drive
• difficulty in sleeping
• sleepiness, dizziness
• numbness and tingling, reduced or altered sensation
• abnormal heartbeat
• hot flushes, increased blood pressure, bleeding
• cough, shortness of breath, chest discomfort or pain
• bronchitis, dry mouth
• flatulence, heartburn/indigestion, constipation, more frequent passing of stools, vomiting, stomach discomfort
• muscle cramps or weakness
• abnormal frequent urination
• tiredness
• gall stones, kidney stones

Stop taking ZURIG 40MG TABLET and inform your doctor immediately, if you
experience any of the following side effects:

• Severe allergic reactions (such as skin rashes, blisters, nodules, itching, swelling of limbs and face, difficulties in breathing, fever, enlargement of lymph nodes)
• Stevens-Johnson-Syndrome (symptoms include reddish target-like spots or circular patches often with central blister on the trunk, ulcers in the mouth, throat, nose, genitals and conjunctivitis, with widespread blistering or peeling of the skin)
• Severe muscle cramps

How To Manage Side Effects

!### Diarrhea

To manage diarrhea caused by medication use, it's important to stay hydrated by
drinking plenty of fluids like water, clear broths, and oral rehydration
solutions to replace lost fluids and electrolytes. Avoid foods that can worsen
diarrhea, such as dairy products, fatty or spicy foods, and high-fiber items.
Instead, opt for a bland diet including bananas, rice, applesauce, and toast
(the BRAT diet). Additionally, probiotics may help restore gut balance. If
diarrhea persists or is accomp
blood in stools, or abdominal pain, seek medical attention promptly.

!### Dizziness Or Drowsiness

To manage dizziness, start by sitting or lying down as soon as you feel dizzy to
avoid falls or injury. Rest in a quiet, safe place until the dizziness passes.
Stay hydrated by drinking plenty of water, as dehydration can worsen dizziness.
Avoid sudden movements, especially when getting up from a seated or lying
position, as this can trigger or worsen symptoms. Consuming light meals and
avoiding alcohol, caffeine, and tobacco can also help. If dizziness persists,
becomes severe, or is accomp
contact your healthcare provider immediately.

Warning & Precautions

!### Pregnancy

ContraindicatedIt is not known whether febuxostat could affect the growing baby. Therefore, do
not take ZURIG 40MG TABLET if you are pregnant or think you may be pregnant
without medical advice.

!### Breastfeeding

ContraindicatedIt is not known whether febuxostat could pass through the breast milk.
Therefore, do not take ZURIG 40MG TABLET if you are breastfeeding without
medical advice.

!### Driving and Using Machines

Use with CautionDo not drive or handle any heavy tools or machines if you experience blurred
vision, dizziness, sleepiness or any other side effects that can affect your
ability to concentrate while undergoing therapy with ZURIG 40MG TABLET.

!### Kidney

Use with CautionZURIG 40MG TABLET should be used with caution in patients with kidney diseases.
Therefore, consult your doctor for advice before taking it.

!### Liver

Use with CautionZURIG 40MG TABLET should be used with caution in patients with liver diseases.
Therefore, consult your doctor for advice before taking it.

!### Allergy

ContraindicatedDo not take ZURIG 40MG TABLET if you are allergic to Febuxostat or allopurinol.

!### Heart Disease

Use with CautionZURIG 40MG TABLET should be used with caution in patients with heart problems
(such as heart failure). Therefore, consult your doctor for advice before taking
it.

!### Use In Pediatrics

ContraindicatedZURIG 40MG TABLET is not recommended for use in children and adolescents (aged
below 18 years) due to lack of safety data. Therefore, consult your doctor
before taking it.

Others

Before taking ZURIG 40MG TABLET, inform your doctor if you:

• have high uric acid levels as a result of Lesch-Nyhan syndrome (a rare inherited condition in which there is too much uric acid in the blood)
• have thyroid problems

Interactions

A. Drug-Drug interactions:

• Mercaptopurine (used for cancer)
• Azathioprine (used to reduce immune response)
• Theophylline (used to manage asthma)

Overdosage:

If you or anyone else accidentally took too much of ZURIG 40MG TABLET, consult
your doctor immediately for advice.

Synopsis

Drug	:	Febuxostat
Pharmacological Category	:	Xanthine oxidase inhibitors
Therapeutic Indication	:	Gout and Hyperuricemia
Dosage Forms	:	Tablet

More Information

Storage

• Keep ZURIG 40MG TABLET out of reach of children
• Store ZURIG 40MG TABLET at room temperature

FAQs About ZURIG 40MG TABLET

Q: What is ZURIG 40MG TABLET used for?

A: ZURIG 40MG TABLET is used in the management of gout and hyperuricemia.

Q: How ZURIG 40MG TABLET works?

A: ZURIG 40MG TABLET works by selectively inhibiting an enzyme called xanthine
oxidase, which plays a key role in the production of uric acid in the body. By
blocking this enzyme, febuxostat reduces the formation of uric acid, thereby
lowering its levels in the blood. This helps reducing the formation of uric acid
crystals, which can cause painful gout attacks and joint damage.

Q: How to take ZURIG 40MG TABLET?

A: Take ZURIG 40MG TABLET as advised by your physician. It can be taken with or
without food. Swallow the medicine with a glass of water. Do not crush or chew
the medicine. Your doctor will decide the correct dose and duration of therapy
for you based on your age, body weight and health condition. Do not stop taking
ZURIG 40MG TABLET without consulting your doctor.

Q: What are the side effects of taking ZURIG 40MG TABLET?

A: The most common side effects of taking ZURIG 40MG TABLET are nausea,
diarrhea, headache, dizziness, sleepiness, flare ups if gout attack, edema and
abnormal liver test results. Consult your doctor if they trouble you.

Q: Can ZURIG 40MG TABLET be used during pregnancy?

A: It is not known whether febuxostat could affect the growing baby. Therefore,
do not take ZURIG 40MG TABLET if you are pregnant or think you may be pregnant
without medical advice.

Q: How long will it take for ZURIG 40MG TABLET to show results?

A: Febuxostat typically begins to lower uric acid levels within a few days of
starting the medication. However, it may take about two weeks to a month to see
significant reductions in uric acid levels. Full therapeutic effects, including
the prevention of gout attacks, are generally observed after several months of
consistent use. It's important to continue taking febuxostat as prescribed by
your doctor, even if you don't see immediate results, and attend regular
follow-ups to monitor uric acid levels and adjust the dosage if necessary.

Q: Can ZURIG 40MG TABLET cause decrease in sex drive?

A: ZURIG 40MG TABLET may reduce sex drive in few individuals. Consult your
doctor if this side effect troubles you.

Q: Can ZURIG 40MG TABLET increase gout attacks?

A: During the initial days of the therapy, febuxostat can cause flare up of gout
attacks in some individuals which is normal. Over the period of use, these flare
ups usually reduce and becomes less painful upon everyday usage. If these flare
ups are not manageable, consult your doctor for advice.

Useful Diagnostic Tests

• Rheumatoid Factor (RF)/RA Test Rheumatoid Arthritis Factor, Qualitative
• Basic Arthritis Care