ZOVIR Cream 15gm

Introduction About ZOVIR CREAM

ZOVIR CREAM contains Acyclovir, which belongs to the group of medicines called
Antivirals. It is used for the management of cold sores associated with the
Herpes simplex virus in immunodeficiency adults and adolescents over 12 years of
age. It can also be used to speed up the healing of sores and shorten the
duration of pain. A cold sore is an infection caused by the herpes simplex virus
most often around the mouth. Symptoms include tiny, fluid-filled lesions called
cold sores, sore lips, ulcers, blisters or rashes on the skin.

Before applying ZOVIR CREAM inform your doctor if you have low immunity, cold
sores in mouth or frequent episodes of cold sores greater than 4 times a year.
ZOVIR CREAM is generally not recommended for use in pregnant women unless it is
considered clearly necessary. ZOVIR CREAM is generally not recommended for use
in breastfeeding women as it may pass through the breast milk.

The most common side effects after applying ZOVIR CREAM are rash, itchy skin,
weal, mild drying or flaking of the skin and dry lips. Contact your doctor if
your side effects gets worse or persists for a longer duration.

Uses Of ZOVIR CREAM

It is used to:

• manage cold sores associated with herpes simplex virus infections
• speeds up the healing process and shortens the duration of pain
• manage recurrent herpes labialis (cold sores) in immunodeficiency adults and adolescents 12 years of age and above

How ZOVIR CREAM Works

ZOVIR CREAM works by against or stopping the growth of viruses (herpes virus).
It has a higher affinity for viral DNA cells than human DNA cells and
incorporates into the viral DNA and causes DNA chain termination and
inactivation, leading to the death of cells.

How to use ZOVIR CREAM

Apply ZOVIR CREAM as directed by your physician. It is for external use only.
Wash your hands with soap and water before applying the medicine. Apply a thin
layer of medicine to the affected area. Do not rub the cold sore because this
may cause the cold sore to spread to other areas or make your cold sore worse.
Use this medicine for up to 5 days.

Side Effects Of ZOVIR CREAM

Common

• burning or stinging feeling
• redness, itching, mild drying or flaking of the skin, skin rashes, hives and weals
• dry or cracked lips
• peeling

Stop applying ZOVIR CREAM and contact your doctor immediately if you experience
any of the following side effects:

• allergic reaction symptoms such as rash, itchy skin, weal, swelling of the lips, face and/or eyelids

How To Manage Side Effects

!### Skin rash Or Itching

Avoid hot showers because hot water can irritate the skin. Do not scratch the
affected area. Use sunscreen and protective clothing when outdoors. Regularly
use unscented moisturizers to soothe and hydrate the affected area. If the
symptom does not improve, contact your doctor.

Warning & Precautions

!### Pregnancy

Consult your doctorInform your doctor if you are pregnant before applying ZOVIR CREAM. Consult your
doctor before applying the medicine.

!### Breastfeeding

ContraindicatedZOVIR CREAM is generally not recommended for use in breastfeeding women as it
may pass through the breast milk. Consult your doctor before applying ZOVIR
CREAM.

!### Allergy

ContraindicatedDo not apply ZOVIR CREAM if you are allergic to Acyclovir, Valacyclovir, or any
of the other ingredients of the medicine.

!### Use In Pediatrics

Use with CautionZOVIR CREAM should be used with caution in children and adolescents under 12
years of age. Consult your doctor before applying ZOVIR CREAM.

!### Use In Geriatrics

Use with CautionZOVIR CREAM should be used with caution in elderly patients (aged above 75
years). Consult your doctor before applying ZOVIR CREAM.

Others

ZOVIR CREAM is not recommended for use if you have:

• mouth ulcers
• herpes infections near the eyes, or in the genital area

Before applying ZOVIR CREAM, inform your doctor:

• if you have low immunity
• if you have frequent episodes of cold sores

Interactions

A. Drug-Drug interactions:

Tell your doctor if you are taking or have recently taken any other medicines,
including medicines obtained without a prescri
herbal products.

Overdosage:

If you or anyone else accidentally use too much of ZOVIR CREAM or if you or a
child accidentally swallow the medicine, consult your doctor immediately or
visit the nearby hospital.

Synopsis

Drug	:	Acyclovir
Pharmacological Category	:	Antivirals
Therapeutic Indication	:	Cold sores
Dosage Forms	:	Tablet, Suspension, Syrup, Infusion, Injection, Cream, Ointment, Eye ointment

More Information

Storage

• Keep ZOVIR CREAM out of the sight and reach from children
• Store ZOVIR CREAM below 25°C

FAQs About ZOVIR CREAM

Q: Can I apply ZOVIR CREAM on genital herpes?

A: No. Do not apply ZOVIR CREAM to any unaffected skin, or genital herpes sores.
Consult your doctor before applying.

Q: Can I use ZOVIR CREAM for impetigo?

A: No. ZOVIR CREAM is used to manage cold sores caused by the herpes simplex
virus. Consult your doctor before applying ZOVIR CREAM.

Q: How long does it take for ZOVIR CREAM to work?

A: ZOVIR CREAM starts working within 24 hours of applying and symptoms gradually
decrease within 3 days. Consult your doctor if the symptom persists.

Q: Can I use ZOVIR CREAM on my lips?

A: Yes. ZOVIR CREAM is used to manage cold sores (fever blisters;blisters that
are caused by a herpes simplex virus) on the face or lips. Consult your doctor
before applying ZOVIR CREAM.

Useful Diagnostic Tests

• Herpes Simplex Virus 1 DNA PCR
• Herpes Simplex Virus 1 IgG
• Herpes Simplex Virus 2 DNA PCR
• Herpes Simplex Virus 2 IgG
• Herpes Simplex Virus 2 IgM