VONOMAC 20 Tablet 10's

Introduction About VONOMAC 20 TABLET

VONOMAC 20 TABLET is used in the management of Gastro-intestinal reflux disease
(GERD), reflux or erosive esophagitis, heartburn, acidity, stomach ulcers and
other complications caused due to excessive stomach acid secretions. It can also
be used as an adjunctive therapy for eradication of Helicobacter pylori
infection in combination with antibiotics (like amoxicillin and clarithromycin).

VONOMAC 20 TABLET contains Vonoprazan which is a Potassium Competitive Acid
Blocker (P-CAB). It works by blocking a specific protein in the stomach lining
which is crucial for producing stomach acid. By inhibiting it, vonoprazan
effectively reduces the amount of acid the stomach produces.

Vonoprazan reduces stomach acid more effectively than traditional proton pump
inhibitors (PPIs), creating a less acidic environment which helps the
antibiotics work better by increasing their stability and concentration in the
stomach, making it easier to eradicate the H. pylori bacteria. VONOMAC 20
TABLET is suitable for use only in adults.

Before taking VONOMAC 20 TABLET, inform your doctor if you have any liver or
kidney problems. You must also inform your doctor if you have low blood
magnesium levels, calcium and potassium levels or if you are pregnant or
breastfeeding.

The most common side effects of taking VONOMAC 20 TABLET are stomach pain,
indigestion, diarrhea, constipation, bloating, high blood pressure, headache,
changes in taste sense, vaginal yeast infection and cold-like symptoms. Consult
your doctor if any of these side effects trouble you.

Uses Of VONOMAC 20 TABLET

Management of Gastrointestinal problems such as:

• GERD and its signs like heartburn, acidity, indigestion
• Reflux or erosive esophagitis
• Stomach ulcers and duodenal ulcers
• Adjunctive therapy for H. pylori infection in combination with antibiotics

How VONOMAC 20 TABLET Works

VONOMAC 20 TABLET contains Vonoprazan which works by blocking a specific protein
in the stomach lining called the potassium ion transporter. This protein is
crucial for producing stomach acid. By inhibiting it, vonoprazan effectively
reduces the amount of acid the stomach produces. This helps in managing
conditions like acid reflux, stomach ulcers, and other acid-related disorders by
allowing the stomach and esophagus to heal.

For H. pylori infection eradication, vonoprazan is used as part of a combination
therapy with antibiotics. Vonoprazan reduces stomach acid more effectively than
traditional proton pump inhibitors (PPIs), creating a less acidic environment.
This enhanced acid suppression helps the antibiotics work better by increasing
their stability and concentration in the stomach, making it easier to eradicate
the H. pylori bacteria and promote healing of the stomach lining.

How to use VONOMAC 20 TABLET

Take VONOMAC 20 TABLET as advised by your physician. It can be taken with or
without food. Swallow the medicine with a glass of water. Do not crush or chew
the medicine.

Your doctor will decide the correct dose and duration of therapy for you
depending on your age, body weight, and health condition. Do not stop taking
VONOMAC 20 TABLET without consulting your doctor.

Overdose

If you or anyone else accidentally taken too many doses of VONOMAC 20 TABLET,
contact your doctor immediately or visit the hospital straight away.

Side Effects Of VONOMAC 20 TABLET

Common side effects of VONOMAC 20 TABLET:

• inflammation of stomach, indigestion, diarrhea, constipation
• stomach bloating, stomach pain, nausea
• high blood pressuref
• urinary tract infection
• headache, changes in taste sense
• vaginal yeast infection
• cold-like symptoms

Stop taking VONOMAC 20 TABLET and inform your doctor immediately if you
experience any of the following side effects:

• Kidney problem (such as acute tubulointerstitial nephritis causing low urine output and bloody urine)
• Severe diarrhea with stomach pain and fever
• Bone fractures (hip, wrist, or spine)
• Severe skin reactions causing skin rashes, blistering, peeling, or bleeding on any part of your skin (including your lips, eyes, mouth, nose, genital, hands, or feet) with fever, chills, body aches, breathing difficulties and enlarged lymph nodes
• Low vitamin-B12 levels causing irregular heartbeat, shortness of breath, lightheadedness, tingling or numbness in the arms and legs, muscle weakness, pale skin, feeling tired, or mood changes
• Low magnesium levels in the body (such as seizures, dizziness, irregular heartbeat, jitteriness, muscle aches or weakness, or spasms of the hands, feet, or voice)
• Stomach growths (fundic gland polyps)

How To Manage Side Effects

!### Dizziness Or Drowsiness

Stay hydrated and avoid sudden movements like standing up quickly, which can
worsen the dizziness. Try to move slowly and sit down if you feel lightheaded.
Resting with your head elevated can also help. Eating small, balanced meals
throughout the day can keep your blood sugar stable, reducing dizziness. Ensure
your home is free of tripping hazards and keep a stable object nearby to hold
onto if needed. If dizziness persists or worsens, consult your healthcare
provider for further guidance.

!### Nausea And Vomiting

Eat small, frequent meals instead of large ones, and avoid greasy, spicy, or
strong-smelling foods. Stay hydrated by sipping clear liquids like water, ginger
ale, or herbal teas throughout the day. Ginger, either in tea, candies, or as a
supplement, can help reduce nausea. Resting in an upright position after eating
can also minimize symptoms. If prescribed by your doctor, take anti-nausea
medications as directed. Additionally, relaxation techniques such as deep
breathing, meditation, or gentle distractions like listening to music can help
manage nausea. Always consult your healthcare provider for personalized advice.

Warning & Precautions

!### Pregnancy

Consult your doctorIt is not known whether Vonoprazan can harm the unborn baby. Therefore, inform
your doctor if you are pregnant or think you may be pregnant before taking
VONOMAC 20 TABLET as a precaution. If you became pregnant while under therapy
with VONOMAC 20 TABLET, inform your doctor immediately.

!### Breastfeeding

Consult your doctorIt is not known whether Vonoprazan can pass through breast milk. Therefore,
inform your doctor before taking VONOMAC 20 TABLET if you are breastfeeding or
planning to breastfeed.

!### Kidney

Use with CautionVONOMAC 20 TABLET should be used with caution in patients with kidney problems.
Therefore, consult your doctor for advice.

!### Liver

Use with CautionVONOMAC 20 TABLET should be used with caution in patients with liver problems.
Therefore, consult your doctor for advice.

!### Allergy

ContraindicatedDo not take VONOMAC 20 TABLET if you are allergic to Vonoprazan.

!### Use In Pediatrics

Consult your doctorThe safety and effectiveness of VONOMAC 20 TABLET have not been established in
children and adolescents (aged 18 years or below). Therefore, consult your
doctor for advice.

Other Warnings for VONOMAC 20 TABLET

Before taking VONOMAC 20 TABLET, inform your doctor if you:

• Have low magnesium levels in the blood
• Have low calcium or potassium levels in the blood
• Are taking medicines to increase urine output

Drug - Drug interaction

• Rilpivirine (an Anti-HIV medicine)

Synopsis

Drug	Vonoprazan
Pharmacological Category	Potassium-competitive acid blocker (P-CAB)
Therapeutic Indication	Stomach ulcers,GERD, H. Pylori infection
Dosage Forms	Tablet

More Information

Storage

• Keep VONOMAC 20 TABLET out of reach of children
• Store VONOMAC 20 TABLET at room temperature

FAQs About VONOMAC 20 TABLET

Q: What is VONOMAC 20 TABLET used for?

A: VONOMAC 20 TABLET is used in the management of Gastro-intestinal reflux
disease (GERD), reflux or erosive esophagitis, heartburn, acidity, stomach
ulcers and other complications caused due to excessive stomach acid secretions.
It can also be used as an adjunctive therapy for eradication of Helicobacter
pylori infection in combination with antibiotics (like amoxicillin and
clarithromycin).

Q: How long should I take VONOMAC 20 TABLET?

A: You need to take VONOMAC 20 TABLET for the stipulated duration prescribed by
your doctor. Your doctor will decide the correct dose and duration of therapy
for you depending upon your age, body weight and disease condition.

Q: What is the best time to take VONOMAC 20 TABLET?

A: VONOMAC 20 TABLET can be taken with or without meals. If you are doubtful,
consult your doctor for advice.

Q: What to do if I forgot to take a dose of VONOMAC 20 TABLET?

A: If you forgot to take a dose of VONOMAC 20 TABLET, take it as soon as you
remember. However, if it is time for the next dose of VONOMAC 20 TABLET, skip
the missed dose and take the next one regularly. Do not take a double dose of
VONOMAC 20 TABLET to compensate the missed ones.

Q: Can I stop taking VONOMAC 20 TABLET without consulting your doctor?

A: No. You should not stop taking VONOMAC 20 TABLET without consulting your
doctor because it may lead to reversal of symptoms. If you feel better after
using VONOMAC 20 TABLET, consult your doctor for advice.

Q: Will taking a higher dose of VONOMAC 20 TABLET be more effective?

A: No, taking a higher dose of VONOMAC 20 TABLET will not be effective rather it
can lead to toxicity. Always take the dose prescribed by your doctor. If the
prescribed dose is not effective for you, consult your doctor for advice. Your
doctor might increase the dose or suggest an alternative therapy.

Q: What are the most common side effects of taking VONOMAC 20 TABLET?

A: The most common side effects of taking VONOMAC 20 TABLET are stomach pain,
indigestion, diarrhea, constipation, bloating, high blood pressure, headache,
changes in taste sense, vaginal yeast infection and cold-like symptoms. Consult
your doctor if any of these side effects trouble you.

Q: Can VONOMAC 20 TABLET cause constipation?

A: Yes. Constipation is a common side effect of using VONOMAC 20 TABLET. Eat
plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as
drink plenty of water and exercise more regularly when taking this medicine.
Contact your doctor if this side effect bothers you.

Q: Can VONOMAC 20 TABLET be used in pregnant women?

A: It is not known whether Vonoprazan can harm the unborn baby. Therefore,
inform your doctor if you are pregnant or think you may be pregnant before
taking VONOMAC 20 TABLET as a precaution. If you became pregnant while under
therapy with VONOMAC 20 TABLET, inform your doctor immediately.

Q: How to take VONOMAC 20 TABLET?

A: Take VONOMAC 20 TABLET as advised by your physician. It can be taken with or
without food. Swallow the medicine with a glass of water. Do not crush or chew
the medicine.

Q: How much VONOMAC 20 TABLET should I take?

A: VONOMAC 20 TABLET should be used only under medical supervision. Your doctor
will decide the correct dose and duration of therapy for you depending upon your
age, body condition and severity of the disease condition.

Useful Diagnostic Tests

• Complete Blood Count (CBC)
• Healthy Midlife Checkup