Twinox 150mg Injection 5ml

Introduction About TWINOX 150MG INJECTION

TWINOX 150MG INJECTION is used in the management of various bacterial infections
such as respiratory tract infections (pneumonia, acute exacerbation of chronic
bronchitis), urinary tract infections (cystitis, urethritis, pyelonephritis),
bone and joint infections (osteomyelitis), middle ear infections (otitis media),
tonsillitis, sinusitis, skin and soft tissue infections such as cellulitis,
boils, wound infections, intra-abdominal sepsis, dental infections, and
infections of genital organs in females.

TWINOX 150MG INJECTION is also used as prophylaxis against various bacterial
infections associated with major surgeries of the heart, joints, kidney, head
and neck, stomach, biliary tract, intestine, and pelvic region. Along with
management with this medicine, your doctor might order bacterial culture tests
to enhance the outcomes of the management.

It contains a combination of medicines called Amoxicillin and Clavul
which belong to the group of medicines called Penicillins and Beta-Lactamase
Inhibitors. It works by preventing the growth of the bacteria and thus clearing
up the infection.

TWINOX 150MG INJECTION is not recommended for use in patients with severe kidney
impairment who had a history of liver problems or jaundice after taking
penicillin antibiotics. It should be used with caution in patients suffering
from glandular fever (a viral infection causing sore throat, high fever,
swelling of salivary glands, etc.), liver disease, kidney disease, who are not
passing urine daily, convulsions (fits), or large intestine inflammation.

TWINOX 150MG INJECTION is not recommended for use in pregnant women unless
necessary. It should be used with caution in breastfeeding women, as it may pass
through breast milk. TWINOX 150MG INJECTION should be used with caution in
children as it may require dose modification.

The most common side effects after receiving TWINOX 150MG INJECTION are
diarrhea, thrush (fungal infection), etc. Consult your doctor immediately if any
of your symptoms get worse or persist.

Uses Of TWINOX 150MG INJECTION

• Management of various bacterial infections

How TWINOX 150MG INJECTION Works

TWINOX 150MG INJECTION helps in managing bacterial infection, where Amoxicillin
works by inhibiting penicillin-binding proteins (which are involved in the
synthesis of the bacterial cell wall), leading to the activation of autolytic
enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall
and death of the bacterial cell, clavul
bacterial enzymes known as beta-lactamases and hence enhances the antibacterial
activity of amoxicillin.

How to use TWINOX 150MG INJECTION

• This medicine will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or intravenous injection.
• Your doctor will decide the exact dose and duration of management for you depending on your age, body weight, and disease condition.

Side Effects Of TWINOX 150MG INJECTION

Common Side Effects of TWINOX 150MG INJECTION:

• diarrhoea
• thrush (candida fungal infection)

Stop receiving TWINOX 150MG INJECTION and consult your doctor immediately in
case you experience:

• severe allergic reaction, which includes rashes, collapsing or fainting, swelling of the face and throat, which may cause difficulty breathing, fever, joint pain, swollen lymph nodes of the neck, armpits, and groin, and red or purple raised spots on skin due to inflammation of blood vessels
• watery diarrhea with blood or mucus, fever, and abdominal pain that occurs due to inflammation of the large intestine

Warning & Precautions

!### Pregnancy

Monitoring requiredTWINOX 150MG INJECTION is not recommended for use in pregnant women unless
necessary.

!### Breastfeeding

Use with CautionTWINOX 150MG INJECTION should be used with caution in breastfeeding women as it
may pass through breast milk.

!### Driving and Using Machines

ContraindicatedDo not drive or operate machinery after receiving TWINOX 150MG INJECTION.

!### Kidney

Consult your doctorTWINOX 150MG INJECTION is not recommended for use in patients with severe kidney
impairment. It should be used with caution in patients suffering from kidney
problems.

!### Liver

Consult your doctorTWINOX 150MG INJECTION is not recommended for use in patients who had a history
of liver problems or jaundice after taking penicillin antibiotics. It should be
used with caution in patients suffering from liver disease.

!### Allergy

ContraindicatedDo not receive TWINOX 150MG INJECTION if you are allergic to amoxicillin,
clavul

!### Use In Pediatrics

Use with CautionTWINOX 150MG INJECTION should be used with caution in children as it may require
dose modification.

!### Use In Geriatrics

Use with CautionTWINOX 150MG INJECTION should be used with caution in the elderly.

Others

Before receiving TWINOX 150MG INJECTION, inform your doctor if you have:

• glandular fever (viral infection causing sore throat, high fever, swelling of salivary glands, etc.)
• not been urinating regularly
• convulsions (fits)
• large intestine inflammation
• urine and blood tests

Interactions

A. Drug-Drug interactions:

Before receiving TWINOX 150MG INJECTION, inform your doctor if you are taking
any of the following medicine:

• medicines used to manage gout (Ex. allopurinol, probenecid)
• medicines used to manage blood clots (Ex. warfarin)
• methotrexate (used for the management of cancer, severe psoriasis)
• medicine used to manage organ transplant rejection (Ex. mycophenolate mofetil)
• medicines used for management of pregnancy (oral contrace

Overdosage:

TWINOX 150MG INJECTION will be administered to you only by a doctor or a nurse
in a hospital, and so it is unlikely to receive an overdose. However, consult
your doctor or nurse immediately if you experience any unusual symptoms.
Symptoms of overdose of TWINOX 150MG INJECTION are nausea, diarrhea, fits, and
an upset stomach.

Synopsis

Drug	:	Amoxicillin, Clavul
Pharmacological Category	:	Penicillins and Beta-Lactamase Inhibitors
Therapeutic Indication	:	Bacterial infections
Dosage Forms	:	Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Drops, Injections

FAQs About TWINOX 150MG INJECTION

Q: What are the uses of TWINOX 150MG INJECTION?

A: TWINOX 150MG INJECTION is used in adults and children for the management of
various bacterial infections such as respiratory tract infections, urinary tract
infections, bone and joint infections, middle ear infections, tonsillitis,
sinusitis, skin and soft tissue infections, intra-abdominal sepsis, dental
infections, and infections of genital organs in females. It is also used as
prophylaxis against various bacterial infections associated with major
surgeries.

Q: What are the side effects of TWINOX 150MG INJECTION?

A: The most common side effects after receiving TWINOX 150MG INJECTION are
vomiting, diarrhea, thrush (fungal infection), etc. Consult your doctor
immediately in case any of the side effects worsen.

Q: How does TWINOX 150MG INJECTION work?

A: TWINOX 150MG INJECTION helps in managing bacterial infection, where
Amoxicillin works by inhibiting penicillin-binding proteins (which are involved
in the synthesis of the bacterial cell wall), leading to the activation of
autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the
cell wall and death of the bacterial cell, clavul
of bacterial enzymes known as beta-lactamases, hence enhancing the antibacterial
activity of amoxicillin.

Q: Is TWINOX 150MG INJECTION safe for use in pregnant and breastfeeding women?

A: No, TWINOX 150MG INJECTION is not recommended for use in pregnant women
unless necessary, and TWINOX 150MG INJECTION should be used with caution in
breastfeeding women as it may pass through breastmilk. Consult your doctor
before receiving TWINOX 150MG INJECTION.

Q: How TWINOX 150MG INJECTION is given?

A: This medicine will be given to you only by a doctor or a nurse into a vein as
an intravenous infusion or intravenous injection. Your doctor will decide the
exact dose and duration of management for you depending on your age, body
weight, and disease condition.

Q: Who should avoid using TWINOX 150MG INJECTION?

A: TWINOX 150MG INJECTION is not recommended for use in patients with severe
kidney impairment, a history of liver problems or jaundice after taking
penicillin antibiotics, or who are allergic to amoxicillin or clavul

Q: What precautions must be taken while using TWINOX 150MG INJECTION?

A: Before receiving TWINOX 150MG INJECTION, inform your doctor if you have
glandular fever, not been urinating regularly, convulsions (fits), large
intestine inflammation, or suffering from kidney problems or liver disease.

Q: Is TWINOX 150MG INJECTION safe for kids?

A: TWINOX 150MG INJECTION should be used with caution in children as it may
require dose modification.

Q: What should I do if I experience an allergic reaction after receiving TWINOX 150MG INJECTION?

A: Signs of an allergic reaction include rash, swelling of the face, lips, or
throat, difficulty breathing, and joint pain. If you experience any of these
symptoms, stop receiving the injection and seek immediate medical help.

Q: Can I drive after receiving TWINOX 150MG INJECTION?

A: It is advised not to drive or operate heavy machinery after receiving this
injection, as it may cause dizziness or other side effects that impair your
ability to perform such tasks.

Q: What happens if I miss a dose of TWINOX 150MG INJECTION?

A: Since the injection is administered by a healthcare professional, it’s
unlikely you will miss a dose. However, if you are receiving treatment on an
outpatient basis and miss a scheduled appointment, contact your healthcare
provider for guidance.

Q: What should I do if I accidentally receive an overdose of TWINOX 150MG INJECTION?

A: Although this injection is administered by a healthcare professional, if an
overdose occurs, symptoms such as nausea, diarrhea, or convulsions may appear.
Contact your healthcare provider immediately for further management

User Feedback

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Kidney Function Test (KFT)
• Liver Function Test (LFT)
• Serum Electrolytes/ Electrolytes Profile
• Urine Routine & Microscopy
• Full Body Checkup – Gold
• Full Body Checkup – Silver