TIMOL Eye Drops 5ml

Introduction About TIMOL EYE DROPS

TIMOL EYE DROPS contains Timolol which belongs to the group of medicines called
Beta-blockers. It is used to manage raised pressure in eyes which occurs in
various conditions including glaucoma and ocular hypertension. Ocular
hypertension is when the pressure inside the eye is higher than normal with no
signs of vision loss. Glaucoma is a group of eye conditions that damage the
o
headache, eye pain and redness, nausea, vomiting, blurred vision and halos
around lights.

Timolol inhibits binding of certain receptors (beta receptors) on the tissues
lining the inner wall of eyeball. These tissues increase the production of
aqueous humor (fluid of the eye). So, by inhibiting beta receptors, there is a
reduction in aqueous humor production and therefore, intraocular pressure
reduces. It is important that your soft contact lenses are removed before using
this medicine and not placed back into your eyes for at least 15 minutes. Prior
to the management, your doctor may want you to take certain eye tests to
understand your existing condition.

TIMOL EYE DROPS is not recommended for use in patients having respiratory
problems like asthma and heart problems. Before using TIMOL EYE DROPS, inform
your doctor if you have or ever had low blood pressure, problems with blood
circulation, thyroid glands, diabetes, or you wear contact lens. TIMOL EYE DROPS
is generally not recommended for use in pregnant and breastfeeding women. There
is only very limited data available on the use of TIMOL EYE DROPS in children.
Consult your doctor before using. The most common side effects of using TIMOL
EYE DROPS are eye irritation, double vision, headache, depression, dizziness,
and nausea. Contact your doctor if any of the symptoms worsen.

Uses Of TIMOL EYE DROPS

• Manage glaucoma and ocular hypertension

How TIMOL EYE DROPS Works

TIMOL EYE DROPS inhibits binding of certain receptors (beta receptors) on the
tissues lining the inner wall of eyeball. These tissues increase the production
of aqueous humor (fluid of the eye). So, by inhibiting beta receptors, there is
a reduction in aqueous humor production and therefore, pressure in the eyes
reduces. The exact mech

How to use TIMOL EYE DROPS

Use TIMOL EYE DROPS as advised by your physician. It is for external use only.
It is important that your soft contact lenses are removed before using this
medicine and not put back into your eyes for at least 15 minutes. Tilt your head
back and pull down your lower eyelid. Make sure you wash your hands and do not
touch any surface while using it. Keep the eyes closed for as long as possible
and apply pressure to the corner of the eye. Your doctor will decide the correct
dose and duration for you depending upon your age, body weight and disease
condition.

Side Effects Of TIMOL EYE DROPS

Common

• eye irritation (Ex. burning, stinging, itching, tearing, redness), inflammation of the eyelid, cornea, blurred vision
• dry eyes, corneal erosion (damage to the front layer of the eyeball), drooping of the upper eyelid (making the eye stay half closed), double vision
• sensitivity to light, discharge from the eye, pain in the eye.
• ringing sound in the ears
• headache
• low blood glucose levels.
• difficulty in sleeping, depression, nightmares, memory loss, hallucination dizziness
• taste disturbances, nausea, diarrhea, dry mouth, abdominal pain, vomiting

Rare

Stop using TIMOL EYE DROPS and contact your doctor immediately if you experience
any of the following side effects:

• allergic reactions including swelling beneath the skin that can occur in the face, limbs and can obstruct the airway which may cause difficulty in swallowing or breathing
• hives or itchy rash, localized and generalized rash, hair loss, skin rash with white silvery colored appearance (psoriasiform rash) or worsening of psoriasis
• slow heart rate, chest pain, palpitations, changes in the rhythm or speed of the heartbeat, shortness of breath, swelling of the feet and legs due to fluid buildup, heart failure, heart attack
• low blood pressure, cold hands and feet, limping
• constriction of the airways in the lungs (predominantly in patients with pre-existing disease), difficulty in breathing, shortness of breath, wheezing, cough
• fainting, stroke, reduced blood supply to the brain, increased signs and symptoms of myasthenia gravis (muscle disorder), dizziness, unusual sensations like tingling and headache
• sexual dysfunction, decreased sex drive, decreased libido in men
• signs and symptoms of systemic lupus erythematosus
• sudden weight gain

How To Manage Side Effects

!### Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated.
Donot consume any medicine on your own without consulting your doctor.

Headache

Drink lots of water, keep a cold/hot pack and avoid bright lights.

!### Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid
eating oily or spicy foods.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller and frequent
meals. Keep a heat pad on your stomach. If the symptom does not improve, contact
your doctor.

Warning & Precautions

!### Pregnancy

Monitoring requiredTIMOL EYE DROPS is not recommended for pregnant women unless its considered
necessary by the doctor. Consult your doctor before using it.

!### Breastfeeding

ContraindicatedTIMOL EYE DROPS is not recommended for breastfeeding women as it can pass
through the milk. Consult your doctor before using it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines until you feel well, and your vision is
clear while using TIMOL EYE DROPS.

!### Allergy

ContraindicatedDo not use TIMOL EYE DROPS if you are allergic to Timolol.

!### Lungs

ContraindicatedTIMOL EYE DROPS is not recommended for patients with respiratory problems such
as asthma, severe chronic obstructive bronchitis (wheezing, difficulty in
breathing and/or long-standing cough). Consult your doctor before using TIMOL
EYE DROPS.

!### Heart Disease

Consult your doctorTIMOL EYE DROPS is not recommended for patients with a slow heartbeat, heart
problems, heart failure, disorders of heart rhythm or with an episode of
cardiogenic shock. It should be used with caution in patients with coronary
heart disease (chest pain or tightness, breathlessness or choking), low blood
pressure, poor blood circulation disease (such as Raynaud's disease or Raynaud's
syndrome). Consult your doctor before using TIMOL EYE DROPS.

!### Use In Pediatrics

Consult your doctorThere is only limited data available on the use of TIMOL EYE DROPS in newborns,
infants, and younger children. Consult your doctor before using.

Others

Before using TIMOL EYE DROPS, inform your doctor if you:

• have diabetes
• have poor blood circulation disease (such as Raynaud's disease or Raynaud's syndrome)
• overactivity of the thyroid gland
• have to undergo a surgery as it may change effects of some medicines used during anesthesia

Interactions

A. Drug - Drug interactions:

Before using TIMOL EYE DROPS, inform your doctor if you are taking any of the
following medicine:

• medicines used to manage diabetes. (Ex. metformin, glimepiride)
• a calcium antagonist (Ex.  nifedipine, verapamil or diltiazem), catecholamine-depleting agents (Ex. rauwolfia alkaloids/reserpine), clonidine to manage high blood pressure
• digoxin (to manage heart failure or an abnormal heartbeat)
• pressor amines (Ex. adrenaline) to manage allergic reaction
• quinidine (to manage heart conditions and some types of malaria)
• other beta-blockers taken by mouth or used as eye drops
• antidepressants (Ex. fluoxetine and paroxetine)

Overdosage:

If you or anyone else accidentally use too much of TIMOL EYE DROPS, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose of TIMOL
EYE DROPS are headache, light-headedness, difficulty in breathing, chest pain,
feeling that your heart rate has slowed down.

Synopsis

Drug	:	Timolol
Pharmacological Category	:	Beta-blockers
Therapeutic Indication	:	Glaucoma, Ocular hypertension
Dosage Forms	:	Eye drops

More Information

• Keep TIMOL EYE DROPS out of reach of children
• Do not store above 25°C

FAQs About TIMOL EYE DROPS

Q: Can I use TIMOL EYE DROPS with contact lenses?

A: No, you should remove your contact lenses before using TIMOL EYE DROPS. You
can wear the lens 15 minutes after using TIMOL EYE DROPS. Contact your doctor in
case of eye irritation.

Q: Can I stop using TIMOL EYE DROPS if I feel fine?

A: No, you should not stop using TIMOL EYE DROPS without consulting your doctor.
Stopping TIMOL EYE DROPS suddenly can disturb the pressure in your eyes which
may increase the risk of loss of sight.

Q: Who should not use TIMOL EYE DROPS?

A: TIMOL EYE DROPS should not be taken if you have asthma or severe COPD, or a
serious heart condition (severe heart failure, or very slow heartbeats). Consult
your doctor for advice.

Q: What happens if I use more TIMOL EYE DROPS?

A: Overdose of TIMOL EYE DROPS can cause headache, light-headedness, difficulty
in breathing, chest pain, feeling that your heart rate has slowed down. Consult
your doctor immediately.

Useful Diagnostic Tests

• Eye examination