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by Unison Pharmaceuticals Pvt Ltd· 10s
SKU: 1173273
You save ₹17 on this order
Inclusive of all taxes
TICAPREV 90 TABLET is a prescri
individuals who have had a heart attack or are at risk of stroke. It works by
inhibiting platelets, thus reducing the risk of clot formation in the blood
vessels.
Your doctor may also prescribe aspirin, an additional antiplatelet medication,
alongside TICAPREV 90 TABLET. You can take TICAPREV 90 TABLET with or without
food, and it is important to take it consistently at the same time each day.
Continue taking the medication as prescribed, even if you feel fine. Stopping it
could raise your risk of having another heart attack or stroke.
Common side effect of this medication includes headache, dizziness, shortness of
breath, dyspnea (breathlessness) and bleeding. If you cut or injure yourself, it
might take longer than normal for the bleeding to stop. These bleeding episodes
are typically mild and should resolve on their own. Mild breathlessness caused
by this medication generally improves with ongoing management. However, inform
your doctor if the bleeding continues or if the breathlessness becomes more
severe or does not improve.
TICAPREV 90 TABLETmay not be appropriate for certain individuals. Avoid taking
it if you are experiencing bleeding anywhere in the body, such as from a stomach
ulcer or internal bleeding in the brain. It is also not recommended for those
with liver conditions. Be sure to inform your doctor about any such problems
before taking this medication.
TICAPREV 90 TABLET works by inhibiting platelet aggregation, which helps reduce
blood clots from forming. It is an antiplatelet medication that selectively and
reversibly binds to the P2Y12 receptor on platelets, blocking the action of ADP
(adenosine diphosphate) and thereby reducing platelet activation and
aggregation. This effect helps reduce cardiovascular events like heart attacks
and strokes in patients with a history of acute coronary syndrome or those
undergoing procedures like stent placement. By reducing clot formation, TICAPREV
90 TABLET lowers the risk of further complications related to blood clots in the
arteries.
Follow your doctor's instructions regarding the exact dosage. Do not exceed the
recommended daily dosage. It is important to follow the prescribed dosage for
o
feel the medication is not working or experience side effects, consult your
doctor immediately.
Like all medicines, TICAPREV 90 TABLET may cause certain side effects in some
individuals, although not everybody gets them.
!### Dizziness Or Drowsiness
!### Pregnancy
ContraindicatedTICAPREV 90 TABLET is not recommended for use in pregnant women. It is important
to consult your doctor before taking this medication.
!### Breastfeeding
ContraindicatedTICAPREV 90 TABLET is not recommended for use in breastfeeding women. It is
important to consult your doctor before taking this medication.
!### Driving and Using Machines
Use with CautionDo not drive or operate machines if you experience dizziness or confusion or
vertigo or syncope.
!### Alcohol
Consult your doctorAvoid consum
!### Kidney
Consult your doctorTICAPREV 90 TABLETis not recommended for use in patients with severe kidney
problems and should be used with caution in patients with mild or moderate
kidney problems. Consult your doctor before taking it.
!### Liver
Consult your doctorTICAPREV 90 TABLET is not recommended for use in patients with severe liver
disease and should be used with caution in patients with mild or moderate liver
disease. Consult your doctor before taking it.
!### Allergy
ContraindicatedDo not take this medication if you are allergic to Ticagrelor or any other
ingredients of this medicine.
!### Lungs
Use with CautionTICAPREV 90 TABLET should be used with caution in patients with asthma or other
lung problems or breathing difficulties. It is important to consult your doctor
before taking this medication.
!### Heart Disease
Use with CautionTICAPREV 90 TABLET should be used with caution in patients with abnormal heart
rate. Consult your doctor before taking it.
!### Use In Pediatrics
ContraindicatedTICAPREV 90 TABLET is not recommended for use in children and adolescents (aged
below 18 years).Consult your pediatrician before giving it.
!### Use In Geriatrics
Use with CautionTICAPREV 90 TABLET should be used with caution in elderly patients (aged 65
years and above).Consult your doctor before taking it.
Before taking TICAPREV 90 TABLET, inform your doctor if you:
TICAPREV 90 TABLET is not recommended for use if you:
| Category | Tips | Purpose/Benefit |
| Dietary Habits | ||
| 1. Heart-Healthy Diet | Focus on fruits, vegetables, whole grains, lean proteins (like fish, poultry, beans), and healthy fats (olive oil, avocados). | These foods provide essential nutrients and antioxidants that help reduce inflammation and maintain healthy blood vessels. |
| 2. Limit Saturated Fats | Avoid foods rich in saturated fats (butter, fatty meats, full-fat dairy products). Opt for plant-based fats like olive oil, nuts, and seeds. | Saturated fats can raise cholesterol levels, increasing the risk of heart disease and stroke. |
| 3. Reduce Sodium Intake | Limit processed and salty foods; aim for less than 2,300 mg of sodium per day. Consider using herbs and spices for flavor. | High sodium intake can contribute to high blood pressure, a major risk factor for heart attacks and strokes. |
| 4. Increase Omega-3 Fatty Acids | Include fatty fish (salmon, mackerel, sardines) and flaxseeds in the diet. Alternatively, consider omega-3 supplements. | Omega-3 fatty acids reduce inflammation, improve blood circulation, and help lower the risk of cardiovascular events. |
| 5. Stay Hydrated | Drink plenty of water throughout the day and limit sugary drinks. | Proper hydration supports o |
| Exercise Routines | ||
| 1. Regular Cardiovascular Exercise | Engage in aerobic activities like walking, jogging, swimming, or cycling for at least 150 minutes per week. | Regular cardiovascular exercise strengthens the heart, improves blood circulation, and helps maintain a healthy weight. |
| 2. Strength Training | Include strength training exercises 2-3 times a week, targeting all major muscle groups. | Strength training increases metabolism, improves muscle mass, and supports overall heart health by reducing body fat. |
| 3. Flexibility & Balance Exercises | Incorporate yoga or Pilates to improve flexibility and balance, 2-3 times a week. | These exercises help reduce stress, improve circulation, and enhance flexibility and posture, all of which support heart health. |
| 4. Daily Physical Activity | Take the stairs instead of the elevator, walk or cycle for short trips, and aim for at least 30 minutes of moderate-intensity exercise daily. | Incorporating more movement into daily activities can reduce sedentary behavior, lower blood pressure, and reduce the risk of heart disease. |
| Preventive Measures | ||
| 1. Manage Stress | Practice stress management techniques such as meditation, mindfulness, deep breathing, or relaxation exercises. | Chronic stress can elevate blood pressure and contribute to heart disease. Managing stress can reduce the risk of heart attacks and strokes. |
| 2. Regular Health Checkups | Schedule regular visits to your healthcare provider for blood pressure checks, cholesterol screening, and blood tests. | Monitoring key health metrics allows for early detection and better management of heart disease risk factors like high blood pressure and cholesterol. |
| 3. Quit Smoking | If you smoke, seek help to quit. Use smoking cessation programs or medications, if necessary. | Smoking is a major risk factor for heart disease, stroke, and other cardiovascular conditions. Quitting significantly reduces these risks. |
| 4. Limit Alcohol Intake | Limit alcohol consum | |
| 5. Maintain a Healthy Weight | Aim for a healthy body mass index (BMI) by combining healthy eating with regular physical activity. | Maintaining a healthy weight reduces the strain on the heart, lowers blood pressure, and helps regulate cholesterol levels. |
| 6. Adequate Sleep | Aim for 7-9 hours of quality sleep each night. Maintain a regular sleep schedule and create a restful environment. | Poor sleep is linked to higher blood pressure, inflammation, and increased risk of heart disease. Proper rest is essential for cardiovascular health. |
Inform your physician if you are taking any of the following medicine before
taking TICAPREV 90 TABLET:
| Drug | : | Ticagrelor |
| Pharmacological Category | : | Antiplatelet agent, P2Y12 receptor antagonist |
| Therapeutic Indication | : | Blood clots |
| Dosage Forms | : | Tablet |
| Aspect | TICAPREV 90 TABLET (Ticagrelor) | Plavix (Clopidogrel) |
| Mech | ||
| Onset of Action | Faster onset (1-3 hours) | Slower onset (2-6 hours) |
| Duration of Action | Shorter duration (approximately 12 hours) | Longer duration (approximately 5-7 days) |
| Metabolism | Primarily metabolized in the liver by CYP3A4 and CYP3A5. | Metabolized in the liver by CYP2C19. |
| Effect on Platelet Function | More potent and consistent inhibition of platelet aggregation. | Less potent and may have variable effect due to genetic differences. |
| Indications | Acute coronary syndrome (ACS), following heart attacks or stenting. | ACS, stroke prevention, peripheral artery disease. |
| Common Side Effects | Shortness of breath, bleeding, bradycardia, elevated uric acid. | Bleeding, bruising, rash, diarrhea. |
| Risk of Bleeding | Moderate risk of bleeding, though less than some other anticoagulants. | Moderate risk of bleeding. |
| Required Dosing | Twice daily (typically 90mg twice a day) | Once daily (75mg dose) |
| Food and Drug Interactions | Interacts with CYP3A4 inhibitors, which may require dose adjustments. | Interactions with CYP2C19 inhibitors, may require dose adjustments. |
| Efficacy in ACS | Proven to reduce the risk of cardiovascular events in ACS. | Effective but may not be as potent in reducing cardiovascular events in ACS. |
| Reversibility | Reversible platelet inhibition, allowing a quicker return of normal platelet function. | Irreversible platelet inhibition, takes longer to recover normal platelet function. |
| Special Considerations | Not recommended in patients with severe liver disease or significant bleeding risk. | Lower efficacy in patients with poor CYP2C19 metabolism. |
Why TICAPREV 90 TABLET(Ticagrelor) stands out:
| Feature | TICAPREV 90 TABLET | Ecotrin (Aspirin) |
| Active Ingredient | Ticagrelor | Acetylsalicylic Acid (Aspirin) |
| Class of Drug | Antiplatelet agent (P2Y12 receptor inhibitor) | Nonsteroidal anti-inflammatory drug (NSAID) |
| Primary Indication | Prevents blood clots in patients with acute coronary syndrome or those with a history of heart attack | Reduces pain, inflammation, and prevents blood clots |
| Mech | ||
| Formulation | Oral tablet (90mg) | Oral tablet (various doses, typically 81mg, 325mg) |
| Onset of Action | Fast-acting, with peak effects within 1.5 hours | Slow onset, with effects occurring within 30-60 minutes |
| Duration of Effect | Longer duration of platelet inhibition (up to 5 days) | Effects last a few hours, depending on the dose |
| Efficacy in Cardiovascular Events | Highly effective in preventing heart attacks, strokes, and other cardiovascular events in high-risk patients | Effective for general clot prevention, but less potent in preventing recurrent cardiovascular events |
| Side Effects | Higher risk of bleeding, shortness of breath, headache, dizziness, bradycardia | GI irritation, ulcers, bleeding, tinnitus (with high doses) |
| Specific Indication for ACS | Indicated for acute coronary syndrome (ACS) patients (e.g., after heart attack or angioplasty) | Not specifically indicated for ACS; more general clot prevention |
| Patient Group | Used in high-risk cardiovascular patients, including those with ACS or a history of heart attack | Commonly used in general cardiovascular prevention and pain relief, suitable for a broader patient group |
| Bleeding Risk | Higher bleeding risk due to more potent platelet inhibition | Moderate bleeding risk, lower than TICAPREV 90 TABLET |
| Reversible Antiplatelet Effect | Yes, effect is reversible upon discontinuation within a short period | No, effect persists for the duration of platelet life (7-10 days) |
| Drug Interactions | Stronger drug interactions due to CYP3A4 metabolism (e.g., statins, antifungals) | Interactions with other blood thinners, certain antihypertensives, and alcohol |
| FDA Approval for Stroke Prevention | Yes, indicated for reducing the risk of stroke in high-risk patients | Not directly indicated for stroke prevention (primarily used for cardiovascular prevention) |
Why TICAPREV 90 TABLET Stands Out:
02.What are some alternative medications or lifestyle changes to manage
heart disease if TICAPREV 90 TABLET is not suitable due to medical reasons, such
as o
| Condition/Reason | Alternative Medication | Mech | |||
| Inability to tolerate TICAPREV 90 TABLET | Aspirin | Antiplatelet, inhibits COX-1 enzyme to reduce clotting | Widely used, effective in preventing heart attacks and strokes | Healthy diet (low-sodium, low-fat), regular exercise, stress management | First-line treatment for many patients, well-tolerated by most |
| Increased bleeding risk with TICAPREV 90 TABLET | Clopidogrel (Plavix) | Antiplatelet, inhibits ADP receptors to prevent platelets from clumping | Effective alternative, often used for patients who cannot tolerate TICAPREV 90 TABLET | Smoking cessation, weight management, alcohol moderation | Often combined with aspirin in dual antiplatelet therapy |
| Chronic Kidney Disease | Prasugrel (Effient) | Antiplatelet, similar to TICAPREV 90 TABLET inhibits ADP receptors | More effective in preventing major cardiovascular events, but may not be suitable in some kidney conditions | Blood pressure management, sodium restriction | Avoid in patients with a history of stroke or TIA |
| Gastric issues or ulcers | Dipyridamole | Antiplatelet, increases the effects of adenosine to inhibit platelet aggregation | Less commonly used but can be effective in stroke prevention | Low-stress activities, proper hydration, sleep hygiene | Often used in combination with aspirin for stroke prevention |
| Risk of thromboembolism after surgery | Warfarin (Coumadin) | Anticoagulant, inhibits vitamin K-dependent clotting factors | Very effective in preventing blood clots but requires monitoring | Regular physical activity, balanced diet, avoiding smoking | Requires frequent INR monitoring and dose adjustments |
| High cardiovascular risk, low tolerance to antiplatelets | Statins (e.g., Atorvastatin, Simvastatin) | Lipid-lowering medication, reduces LDL cholesterol to prevent plaque buildup | Can reduce the risk of heart attacks, strokes, and death | Heart-healthy diet, weight loss, aerobic exercise | Statins reduce the risk of atherosclerosis and improve overall cardiovascular health |
A: TICAPREV 90 TABLET is a prescri
blood clots in patients who have experienced a heart attack, unstable angina, or
have certain types of heart disease. It is also used to reduce the risk of
future heart attacks or strokes in patients with a history of cardiovascular
issues.
A: TICAPREV 90 TABLET works by inhibiting platelet aggregation, which reduce
blood clots from forming. It specifically blocks the P2Y12 receptor on
platelets, reducing the ability of platelets to stick together and form clots
that could lead to heart attacks or strokes.
A: Although TICAPREV 90 TABLET is often referred to as a "blood thinner," it is
not a traditional anticoagulant. It is an antiplatelet drug that reduce
platelets in the blood from sticking together and forming clots, which helps to
reduce the risk of heart attacks and strokes.
A: It is generally not recommended to drink alcohol while taking TICAPREV 90
TABLET. Alcohol can increase the risk of bleeding and may interfere with the
effectiveness of the medication. Always consult your doctor before consuming
alcohol while on TICAPREV 90 TABLET.
A: TICAPREV 90 TABLET is available only by prescri
prescri
medical condition and history.
A: TICAPREV 90 TABLET should be stored at room temperature, away from heat,
moisture, and direct light. Keep the medication in its original packaging and
out of reach of children. Do not store it in the bathroom.
A: It is important to buy TICAPREV 90 TABLET only from a reputable pharmacy.
Purchasing medications online without a prescri
may be unsafe and illegal. Always consult your doctor before buying medication
online.
A: TICAPREV 90 TABLET typically stays in your system for about 48 hours after
the last dose. However, its effects on platelet function can last longer. The
medication has a half-life of around 7 hours, but it may take a few days for it
to be completely eliminated from your body.
A: Do not stop taking TICAPREV 90 TABLET suddenly without consulting your
doctor. Abruptly discontinuing the medication can increase the risk of blood
clots, heart attack, or stroke. Your doctor will guide you on how to safely stop
or adjust your dosage.
A: TICAPREV 90 TABLET can interact with other medications, including
anticoagulants, aspirin, and certain drugs used for epilepsy or fungal
infections. Always inform your doctor about all the medications you are taking,
including over-the-counter drugs, supplements, and herbal remedies, to avoid
potential drug interactions.
A: If you are planning surgery, inform your doctor that you are taking TICAPREV
90 TABLET. You may need to stop taking the medication for a period before the
surgery to reduce the risk of excessive bleeding. Your doctor will provide
specific instructions regarding when to discontinue TICAPREV 90 TABLET prior to
surgery.
A: TICAPREV 90 TABLET should be used during pregnancy only if the potential
benefits outweigh the risks. It is not recommended during breastfeeding as it
may pass into breast milk and affect the baby. Always discuss with your doctor
if you are pregnant, planning to become pregnant, or breastfeeding before taking
TICAPREV 90 TABLET.
A: Long-term use of TICAPREV 90 TABLET may increase the risk of bleeding and
other side effects. However, for many patients, the benefits of reducing the
risk of heart attacks and strokes outweigh the potential risks. Regular
monitoring by a doctor is important to ensure that it remains safe and
effective.
TICAPREV 90 TABLET is a prescri
individuals who have had a heart attack or are at risk of stroke. It works by
inhibiting platelets, thus reducing the risk of clot formation in the blood
vessels.
Your doctor may also prescribe aspirin, an additional antiplatelet medication,
alongside TICAPREV 90 TABLET. You can take TICAPREV 90 TABLET with or without
food, and it is important to take it consistently at the same time each day.
Continue taking the medication as prescribed, even if you feel fine. Stopping it
could raise your risk of having another heart attack or stroke.
Common side effect of this medication includes headache, dizziness, shortness of
breath, dyspnea (breathlessness) and bleeding. If you cut or injure yourself, it
might take longer than normal for the bleeding to stop. These bleeding episodes
are typically mild and should resolve on their own. Mild breathlessness caused
by this medication generally improves with ongoing management. However, inform
your doctor if the bleeding continues or if the breathlessness becomes more
severe or does not improve.
TICAPREV 90 TABLETmay not be appropriate for certain individuals. Avoid taking
it if you are experiencing bleeding anywhere in the body, such as from a stomach
ulcer or internal bleeding in the brain. It is also not recommended for those
with liver conditions. Be sure to inform your doctor about any such problems
before taking this medication.
TICAPREV 90 TABLET works by inhibiting platelet aggregation, which helps reduce
blood clots from forming. It is an antiplatelet medication that selectively and
reversibly binds to the P2Y12 receptor on platelets, blocking the action of ADP
(adenosine diphosphate) and thereby reducing platelet activation and
aggregation. This effect helps reduce cardiovascular events like heart attacks
and strokes in patients with a history of acute coronary syndrome or those
undergoing procedures like stent placement. By reducing clot formation, TICAPREV
90 TABLET lowers the risk of further complications related to blood clots in the
arteries.
Follow your doctor's instructions regarding the exact dosage. Do not exceed the
recommended daily dosage. It is important to follow the prescribed dosage for
o
feel the medication is not working or experience side effects, consult your
doctor immediately.
Like all medicines, TICAPREV 90 TABLET may cause certain side effects in some
individuals, although not everybody gets them.
!### Dizziness Or Drowsiness
!### Pregnancy
ContraindicatedTICAPREV 90 TABLET is not recommended for use in pregnant women. It is important
to consult your doctor before taking this medication.
!### Breastfeeding
ContraindicatedTICAPREV 90 TABLET is not recommended for use in breastfeeding women. It is
important to consult your doctor before taking this medication.
!### Driving and Using Machines
Use with CautionDo not drive or operate machines if you experience dizziness or confusion or
vertigo or syncope.
!### Alcohol
Consult your doctorAvoid consum
!### Kidney
Consult your doctorTICAPREV 90 TABLETis not recommended for use in patients with severe kidney
problems and should be used with caution in patients with mild or moderate
kidney problems. Consult your doctor before taking it.
!### Liver
Consult your doctorTICAPREV 90 TABLET is not recommended for use in patients with severe liver
disease and should be used with caution in patients with mild or moderate liver
disease. Consult your doctor before taking it.
!### Allergy
ContraindicatedDo not take this medication if you are allergic to Ticagrelor or any other
ingredients of this medicine.
!### Lungs
Use with CautionTICAPREV 90 TABLET should be used with caution in patients with asthma or other
lung problems or breathing difficulties. It is important to consult your doctor
before taking this medication.
!### Heart Disease
Use with CautionTICAPREV 90 TABLET should be used with caution in patients with abnormal heart
rate. Consult your doctor before taking it.
!### Use In Pediatrics
ContraindicatedTICAPREV 90 TABLET is not recommended for use in children and adolescents (aged
below 18 years).Consult your pediatrician before giving it.
!### Use In Geriatrics
Use with CautionTICAPREV 90 TABLET should be used with caution in elderly patients (aged 65
years and above).Consult your doctor before taking it.
Before taking TICAPREV 90 TABLET, inform your doctor if you:
TICAPREV 90 TABLET is not recommended for use if you:
| Category | Tips | Purpose/Benefit |
| Dietary Habits | ||
| 1. Heart-Healthy Diet | Focus on fruits, vegetables, whole grains, lean proteins (like fish, poultry, beans), and healthy fats (olive oil, avocados). | These foods provide essential nutrients and antioxidants that help reduce inflammation and maintain healthy blood vessels. |
| 2. Limit Saturated Fats | Avoid foods rich in saturated fats (butter, fatty meats, full-fat dairy products). Opt for plant-based fats like olive oil, nuts, and seeds. | Saturated fats can raise cholesterol levels, increasing the risk of heart disease and stroke. |
| 3. Reduce Sodium Intake | Limit processed and salty foods; aim for less than 2,300 mg of sodium per day. Consider using herbs and spices for flavor. | High sodium intake can contribute to high blood pressure, a major risk factor for heart attacks and strokes. |
| 4. Increase Omega-3 Fatty Acids | Include fatty fish (salmon, mackerel, sardines) and flaxseeds in the diet. Alternatively, consider omega-3 supplements. | Omega-3 fatty acids reduce inflammation, improve blood circulation, and help lower the risk of cardiovascular events. |
| 5. Stay Hydrated | Drink plenty of water throughout the day and limit sugary drinks. | Proper hydration supports o |
| Exercise Routines | ||
| 1. Regular Cardiovascular Exercise | Engage in aerobic activities like walking, jogging, swimming, or cycling for at least 150 minutes per week. | Regular cardiovascular exercise strengthens the heart, improves blood circulation, and helps maintain a healthy weight. |
| 2. Strength Training | Include strength training exercises 2-3 times a week, targeting all major muscle groups. | Strength training increases metabolism, improves muscle mass, and supports overall heart health by reducing body fat. |
| 3. Flexibility & Balance Exercises | Incorporate yoga or Pilates to improve flexibility and balance, 2-3 times a week. | These exercises help reduce stress, improve circulation, and enhance flexibility and posture, all of which support heart health. |
| 4. Daily Physical Activity | Take the stairs instead of the elevator, walk or cycle for short trips, and aim for at least 30 minutes of moderate-intensity exercise daily. | Incorporating more movement into daily activities can reduce sedentary behavior, lower blood pressure, and reduce the risk of heart disease. |
| Preventive Measures | ||
| 1. Manage Stress | Practice stress management techniques such as meditation, mindfulness, deep breathing, or relaxation exercises. | Chronic stress can elevate blood pressure and contribute to heart disease. Managing stress can reduce the risk of heart attacks and strokes. |
| 2. Regular Health Checkups | Schedule regular visits to your healthcare provider for blood pressure checks, cholesterol screening, and blood tests. | Monitoring key health metrics allows for early detection and better management of heart disease risk factors like high blood pressure and cholesterol. |
| 3. Quit Smoking | If you smoke, seek help to quit. Use smoking cessation programs or medications, if necessary. | Smoking is a major risk factor for heart disease, stroke, and other cardiovascular conditions. Quitting significantly reduces these risks. |
| 4. Limit Alcohol Intake | Limit alcohol consum | |
| 5. Maintain a Healthy Weight | Aim for a healthy body mass index (BMI) by combining healthy eating with regular physical activity. | Maintaining a healthy weight reduces the strain on the heart, lowers blood pressure, and helps regulate cholesterol levels. |
| 6. Adequate Sleep | Aim for 7-9 hours of quality sleep each night. Maintain a regular sleep schedule and create a restful environment. | Poor sleep is linked to higher blood pressure, inflammation, and increased risk of heart disease. Proper rest is essential for cardiovascular health. |
Inform your physician if you are taking any of the following medicine before
taking TICAPREV 90 TABLET:
| Drug | : | Ticagrelor |
| Pharmacological Category | : | Antiplatelet agent, P2Y12 receptor antagonist |
| Therapeutic Indication | : | Blood clots |
| Dosage Forms | : | Tablet |
| Aspect | TICAPREV 90 TABLET (Ticagrelor) | Plavix (Clopidogrel) |
| Mech | ||
| Onset of Action | Faster onset (1-3 hours) | Slower onset (2-6 hours) |
| Duration of Action | Shorter duration (approximately 12 hours) | Longer duration (approximately 5-7 days) |
| Metabolism | Primarily metabolized in the liver by CYP3A4 and CYP3A5. | Metabolized in the liver by CYP2C19. |
| Effect on Platelet Function | More potent and consistent inhibition of platelet aggregation. | Less potent and may have variable effect due to genetic differences. |
| Indications | Acute coronary syndrome (ACS), following heart attacks or stenting. | ACS, stroke prevention, peripheral artery disease. |
| Common Side Effects | Shortness of breath, bleeding, bradycardia, elevated uric acid. | Bleeding, bruising, rash, diarrhea. |
| Risk of Bleeding | Moderate risk of bleeding, though less than some other anticoagulants. | Moderate risk of bleeding. |
| Required Dosing | Twice daily (typically 90mg twice a day) | Once daily (75mg dose) |
| Food and Drug Interactions | Interacts with CYP3A4 inhibitors, which may require dose adjustments. | Interactions with CYP2C19 inhibitors, may require dose adjustments. |
| Efficacy in ACS | Proven to reduce the risk of cardiovascular events in ACS. | Effective but may not be as potent in reducing cardiovascular events in ACS. |
| Reversibility | Reversible platelet inhibition, allowing a quicker return of normal platelet function. | Irreversible platelet inhibition, takes longer to recover normal platelet function. |
| Special Considerations | Not recommended in patients with severe liver disease or significant bleeding risk. | Lower efficacy in patients with poor CYP2C19 metabolism. |
Why TICAPREV 90 TABLET(Ticagrelor) stands out:
| Feature | TICAPREV 90 TABLET | Ecotrin (Aspirin) |
| Active Ingredient | Ticagrelor | Acetylsalicylic Acid (Aspirin) |
| Class of Drug | Antiplatelet agent (P2Y12 receptor inhibitor) | Nonsteroidal anti-inflammatory drug (NSAID) |
| Primary Indication | Prevents blood clots in patients with acute coronary syndrome or those with a history of heart attack | Reduces pain, inflammation, and prevents blood clots |
| Mech | ||
| Formulation | Oral tablet (90mg) | Oral tablet (various doses, typically 81mg, 325mg) |
| Onset of Action | Fast-acting, with peak effects within 1.5 hours | Slow onset, with effects occurring within 30-60 minutes |
| Duration of Effect | Longer duration of platelet inhibition (up to 5 days) | Effects last a few hours, depending on the dose |
| Efficacy in Cardiovascular Events | Highly effective in preventing heart attacks, strokes, and other cardiovascular events in high-risk patients | Effective for general clot prevention, but less potent in preventing recurrent cardiovascular events |
| Side Effects | Higher risk of bleeding, shortness of breath, headache, dizziness, bradycardia | GI irritation, ulcers, bleeding, tinnitus (with high doses) |
| Specific Indication for ACS | Indicated for acute coronary syndrome (ACS) patients (e.g., after heart attack or angioplasty) | Not specifically indicated for ACS; more general clot prevention |
| Patient Group | Used in high-risk cardiovascular patients, including those with ACS or a history of heart attack | Commonly used in general cardiovascular prevention and pain relief, suitable for a broader patient group |
| Bleeding Risk | Higher bleeding risk due to more potent platelet inhibition | Moderate bleeding risk, lower than TICAPREV 90 TABLET |
| Reversible Antiplatelet Effect | Yes, effect is reversible upon discontinuation within a short period | No, effect persists for the duration of platelet life (7-10 days) |
| Drug Interactions | Stronger drug interactions due to CYP3A4 metabolism (e.g., statins, antifungals) | Interactions with other blood thinners, certain antihypertensives, and alcohol |
| FDA Approval for Stroke Prevention | Yes, indicated for reducing the risk of stroke in high-risk patients | Not directly indicated for stroke prevention (primarily used for cardiovascular prevention) |
Why TICAPREV 90 TABLET Stands Out:
02.What are some alternative medications or lifestyle changes to manage
heart disease if TICAPREV 90 TABLET is not suitable due to medical reasons, such
as o
| Condition/Reason | Alternative Medication | Mech | |||
| Inability to tolerate TICAPREV 90 TABLET | Aspirin | Antiplatelet, inhibits COX-1 enzyme to reduce clotting | Widely used, effective in preventing heart attacks and strokes | Healthy diet (low-sodium, low-fat), regular exercise, stress management | First-line treatment for many patients, well-tolerated by most |
| Increased bleeding risk with TICAPREV 90 TABLET | Clopidogrel (Plavix) | Antiplatelet, inhibits ADP receptors to prevent platelets from clumping | Effective alternative, often used for patients who cannot tolerate TICAPREV 90 TABLET | Smoking cessation, weight management, alcohol moderation | Often combined with aspirin in dual antiplatelet therapy |
| Chronic Kidney Disease | Prasugrel (Effient) | Antiplatelet, similar to TICAPREV 90 TABLET inhibits ADP receptors | More effective in preventing major cardiovascular events, but may not be suitable in some kidney conditions | Blood pressure management, sodium restriction | Avoid in patients with a history of stroke or TIA |
| Gastric issues or ulcers | Dipyridamole | Antiplatelet, increases the effects of adenosine to inhibit platelet aggregation | Less commonly used but can be effective in stroke prevention | Low-stress activities, proper hydration, sleep hygiene | Often used in combination with aspirin for stroke prevention |
| Risk of thromboembolism after surgery | Warfarin (Coumadin) | Anticoagulant, inhibits vitamin K-dependent clotting factors | Very effective in preventing blood clots but requires monitoring | Regular physical activity, balanced diet, avoiding smoking | Requires frequent INR monitoring and dose adjustments |
| High cardiovascular risk, low tolerance to antiplatelets | Statins (e.g., Atorvastatin, Simvastatin) | Lipid-lowering medication, reduces LDL cholesterol to prevent plaque buildup | Can reduce the risk of heart attacks, strokes, and death | Heart-healthy diet, weight loss, aerobic exercise | Statins reduce the risk of atherosclerosis and improve overall cardiovascular health |
A: TICAPREV 90 TABLET is a prescri
blood clots in patients who have experienced a heart attack, unstable angina, or
have certain types of heart disease. It is also used to reduce the risk of
future heart attacks or strokes in patients with a history of cardiovascular
issues.
A: TICAPREV 90 TABLET works by inhibiting platelet aggregation, which reduce
blood clots from forming. It specifically blocks the P2Y12 receptor on
platelets, reducing the ability of platelets to stick together and form clots
that could lead to heart attacks or strokes.
A: Although TICAPREV 90 TABLET is often referred to as a "blood thinner," it is
not a traditional anticoagulant. It is an antiplatelet drug that reduce
platelets in the blood from sticking together and forming clots, which helps to
reduce the risk of heart attacks and strokes.
A: It is generally not recommended to drink alcohol while taking TICAPREV 90
TABLET. Alcohol can increase the risk of bleeding and may interfere with the
effectiveness of the medication. Always consult your doctor before consuming
alcohol while on TICAPREV 90 TABLET.
A: TICAPREV 90 TABLET is available only by prescri
prescri
medical condition and history.
A: TICAPREV 90 TABLET should be stored at room temperature, away from heat,
moisture, and direct light. Keep the medication in its original packaging and
out of reach of children. Do not store it in the bathroom.
A: It is important to buy TICAPREV 90 TABLET only from a reputable pharmacy.
Purchasing medications online without a prescri
may be unsafe and illegal. Always consult your doctor before buying medication
online.
A: TICAPREV 90 TABLET typically stays in your system for about 48 hours after
the last dose. However, its effects on platelet function can last longer. The
medication has a half-life of around 7 hours, but it may take a few days for it
to be completely eliminated from your body.
A: Do not stop taking TICAPREV 90 TABLET suddenly without consulting your
doctor. Abruptly discontinuing the medication can increase the risk of blood
clots, heart attack, or stroke. Your doctor will guide you on how to safely stop
or adjust your dosage.
A: TICAPREV 90 TABLET can interact with other medications, including
anticoagulants, aspirin, and certain drugs used for epilepsy or fungal
infections. Always inform your doctor about all the medications you are taking,
including over-the-counter drugs, supplements, and herbal remedies, to avoid
potential drug interactions.
A: If you are planning surgery, inform your doctor that you are taking TICAPREV
90 TABLET. You may need to stop taking the medication for a period before the
surgery to reduce the risk of excessive bleeding. Your doctor will provide
specific instructions regarding when to discontinue TICAPREV 90 TABLET prior to
surgery.
A: TICAPREV 90 TABLET should be used during pregnancy only if the potential
benefits outweigh the risks. It is not recommended during breastfeeding as it
may pass into breast milk and affect the baby. Always discuss with your doctor
if you are pregnant, planning to become pregnant, or breastfeeding before taking
TICAPREV 90 TABLET.
A: Long-term use of TICAPREV 90 TABLET may increase the risk of bleeding and
other side effects. However, for many patients, the benefits of reducing the
risk of heart attacks and strokes outweigh the potential risks. Regular
monitoring by a doctor is important to ensure that it remains safe and
effective.